2. Name: Abdul QaharName: Abdul Qahar
Presentation topic:diversity ofPresentation topic:diversity of
hormone receptershormone recepters
Presented to:Presented to:
Sir, bakhtareen khan..Sir, bakhtareen khan..
ABDUL WALI KHAN UNIVERSITY MARDAN
(BUNER CAMPUS)
3. What is hormone?What is hormone?
What is the need of hormoneWhat is the need of hormone
receptersrecepters??
4.
5. 1. a protein molecule,present. on the surface of a cell, that
is capable of binding to a complementary molecule, as a
hormone, antibody, or antigen.
• There are two functional clasess of recepters
1. Ionotropic
2. metabotropic
8. Location for different types ofLocation for different types of
hormone:hormone:
On the surface of the cellOn the surface of the cell
membrane e.g.membrane e.g. proteins andproteins and
polypeptidespolypeptides
In the cell cytoplasmIn the cell cytoplasm steroidsteroid
hormoneshormones
In the cell nucleusIn the cell nucleus TT33 & T& T44
9. Hormone
Receptor
Cell membrane
(surface/ inside)
Inside cell
(Cytoplasm/
Nucleus)
HR Complex (Change in function of cell)
Direct action 2nd
Messenger
System
Action on Genetic Machinery
Ion
channels_
Linked
receptors
G-Proteins-
Linked
Receptors
Enzyme-
linked
receptors
Activation of genes
cAMP
Phspholipase C
Ca++
-Calmodulin
Protein synthesis
Gene transcription
1
2 3
4
5
6
7
10. 1. Ion channel linked receptors are cell membrane bound receptors. They act
through synaptic signaling on electrically excitable cells. The ion channels
opening and closing is controlled by neurotransmitter