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You are a dentist treating a patient with ectodermal dysplasia, a disorder that causes such severe
tooth deformities that patients can require dentures even as small children. Ectodermal dysplasia
can be caused by mutations in over a dozen different genes. Depending on which gene is
mutated, the disorder can segregate as autosomal dominant, autosomal recessive, or X-linked
recessive. You collect a family history (see pedigree below) to try to determine what mutation this
patient carries. Assume that II-1, II4 , and 116 are not carriers. Which modes of inheritance can
you exclude based on this pedigree? A. autosomal dominant and autosomal recessive B.
autosomal dominant and X-linked recessive C. autosomal dominant D. autosomal recessive E. X-
linked recessive

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You are a dentist treating a patient with ectodermal dysplas.pdf

  • 1. You are a dentist treating a patient with ectodermal dysplasia, a disorder that causes such severe tooth deformities that patients can require dentures even as small children. Ectodermal dysplasia can be caused by mutations in over a dozen different genes. Depending on which gene is mutated, the disorder can segregate as autosomal dominant, autosomal recessive, or X-linked recessive. You collect a family history (see pedigree below) to try to determine what mutation this patient carries. Assume that II-1, II4 , and 116 are not carriers. Which modes of inheritance can you exclude based on this pedigree? A. autosomal dominant and autosomal recessive B. autosomal dominant and X-linked recessive C. autosomal dominant D. autosomal recessive E. X- linked recessive