this is a summary of RENIN-ANGIOTENSIN-ALDOSTERONE systeme easy to understand!

1. Prepared by NSANZIMANA VEDASTE
UR-CMHS, BLS Department

3. Angiotensin
 Any of several polypeptides that narrow blood
vessels and thus regulate arterial pressure
Renin
 A circulating enzyme released by mammalian
kidneys that converts angiotensinogen to
angiotensin-I that plays a role in maintaining
blood pressure
Aquaporin
 Any of a class of proteins that form pores in the
membrane of biological cells

5.  Renin,
a hormone produced the
juxtaglomerular apparatus in the kidneys,
converts angiotensinogen (which is made in
the liver) to angiotensin I.
 Angiotensin I is then converted to angiotensin
II by the angiotensin converting enzyme
(ACE), increasing blood pressure by causing
vasoconstriction of the blood vessels.

6.  Angiotensin
II causes the release of aldosterone
which is produced by the adrenal cortex; it
functions to maintain both sodium and water
levels (osmotic balance) in the blood.
 Angiotensin II also causes the release of
antidiuretic hormone (ADH) which functions to
conserve water in the body when volume is low; it
does this by inserting aquaporins in the collecting
duct of the nephron to promote water
reabsorption.
.

7.  The
atrial natriuretic peptide (ANP) is another
hormone that is produced to function as a
vasodilator and lower blood pressure by
preventing sodium reabsorption

8. Thank
you