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Proline (cas 344-25-2) MSDS
1.
1.1

IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product identifiers
Product name

D-Proline

Product Number
Brand
CAS-No.

1.2

:
:
:
:

858919

Relevant identified uses of the substance or mixture and uses advised against
Identified uses

2.
2.1

344-25-2

:

Laboratory chemicals, Manufacture of substances

HAZARDS IDENTIFICATION
Classification of the substance or mixture
Not a dangerous substance according to GHS.
This substance is not classified as dangerous according to Directive 67/548/EEC.

2.2

Label elements

2.3

The product does not need to be labelled in accordance with EC directives or respective national laws.
Other hazards - none

3.
3.1

COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Synonyms

:

(R)-Pyrrolidine-2-carboxylic acid

Formula
Molecular Weight

:
:

C5H9NO2
115,13 g/mol

Component

Concentration

D-(+)-Proline
CAS-No.
EC-No.

344-25-2
206-452-7

-

- 858919

4.
4.1

FIRST AID MEASURES
Description of first aid measures
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.

In case of skin contact
Wash off with soap and plenty of water.

In case of eye contact
Flush eyes with water as a precaution.

If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.

4.2

Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.

4.3

Indication of immediate medical attention and special treatment needed
no data available

5.
5.1

FIRE-FIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2

Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx)

5.3

Precautions for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.

5.4

Further information
no data available

6.
6.1

ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing vapors, mist or gas.

6.2

Environmental precautions
Do not let product enter drains.

6.3

Methods and materials for containment and cleaning up
Sweep up and shovel. Keep in suitable, closed containers for disposal.

6.4

Reference to other sections
For disposal see section 13.

7.
7.1

HANDLING AND STORAGE
Precautions for safe handling
Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
protection.

7.2

Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

7.3

Specific end uses
no data available

- 858919

8.
8.1
8.2

EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
General industrial hygiene practice.

Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards
such as NIOSH (US) or EN 166(EU).

Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the
standard EN 374 derived from it.

Body Protection
Choose body protection in relation to its type, to the concentration and amount of dangerous
substances, and to the specific work-place., The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection
Respiratory protection is not required. Where protection from nuisance levels of dusts are desired,
use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN (EU).

9.
9.1

PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) Appearance

Form: powder
Colour: white

b) Odour
c) Odour Threshold
d) pH

no data available
no data available
no data available
e) Melting/freezing point
Melting point/range: 223 °C - dec.
f) Initial boiling point and
no data available
boiling range
g) Flash point
no data available
h) Evaporation rate
no data available
i) Flammability (solid, gas) no data available
j)

Upper/lower
flammability or
explosive limits
k) Vapour pressure
l) Vapour density
m) Relative density
n) Water solubility

no data available

no data available
no data available
no data available
no data available

- 858919

o) Partition coefficient: noctanol/water
p) Autoignition
temperature
q) Decomposition
temperature
r) Viscosity

no data available

s) Explosive properties
t) Oxidizing properties

9.2

no data available

no data available
no data available

no data available

no data available

Other safety information
no data available

10. STABILITY AND REACTIVITY
10.1 Reactivity
no data available

10.2 Chemical stability
no data available

10.3 Possibility of hazardous reactions
no data available

10.4 Conditions to avoid
no data available

10.5 Incompatible materials
Strong oxidizing agents

10.6 Hazardous decomposition products
Other decomposition products - no data available

11. TOXICOLOGICAL INFORMATION
11.1 Information on toxicological effects
Acute toxicity
no data available

Skin corrosion/irritation
no data available

Serious eye damage/eye irritation
no data available

Respiratory or skin sensitization
no data available

Germ cell mutagenicity
no data available

Carcinogenicity
IARC:

No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.

Reproductive toxicity
no data available

Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
- 858919

Aspiration hazard
no data available

Potential health effects
Inhalation
May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion
May be harmful if swallowed.
Skin
May be harmful if absorbed through skin. May cause skin irritation.
Eyes
May cause eye irritation.
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.

Additional Information
RTECS: Not available

12. ECOLOGICAL INFORMATION
12.1 Toxicity
no data available

12.2 Persistence and degradability
no data available

12.3 Bioaccumulative potential
no data available

12.4 Mobility in soil
no data available

12.5 Results of PBT and vPvB assessment
no data available

12.6 Other adverse effects
no data available

13. DISPOSAL CONSIDERATIONS
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging
Dispose of as unused product.

14. TRANSPORT INFORMATION
14.1 UN-Number
ADR/RID: -

IMDG: -

IATA: -

IMDG: -

IATA: -

IMDG: -

IATA: -

IMDG Marine pollutant: no

IATA: no

14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG:
Not dangerous goods
IATA:
Not dangerous goods

14.3 Transport hazard class(es)
ADR/RID: -

14.4 Packaging group
ADR/RID: -

14.5 Environmental hazards
ADR/RID: no

14.6 Special precautions for users
no data available
- 858919

15.

REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available

15.2 Chemical Safety Assessment
no data available

16.

OTHER INFORMATION
Further information
The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information this document is based on the resent state
of our knowledge and is applicable to the product with regard to appropriate safety precautions.
It does not represent any guarantee of the properties of the product. guidechem shall not be
held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.

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Proline CAS:344 25-2

  • 1. Click http://www.guidechem.com/cas-344/344-25-2.html for suppliers of this product Proline (cas 344-25-2) MSDS 1. 1.1 IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING Product identifiers Product name D-Proline Product Number Brand CAS-No. 1.2 : : : : 858919 Relevant identified uses of the substance or mixture and uses advised against Identified uses 2. 2.1 344-25-2 : Laboratory chemicals, Manufacture of substances HAZARDS IDENTIFICATION Classification of the substance or mixture Not a dangerous substance according to GHS. This substance is not classified as dangerous according to Directive 67/548/EEC. 2.2 Label elements 2.3 The product does not need to be labelled in accordance with EC directives or respective national laws. Other hazards - none 3. 3.1 COMPOSITION/INFORMATION ON INGREDIENTS Substances Synonyms : (R)-Pyrrolidine-2-carboxylic acid Formula Molecular Weight : : C5H9NO2 115,13 g/mol Component Concentration D-(+)-Proline CAS-No. EC-No. 344-25-2 206-452-7 - - 858919 4. 4.1 FIRST AID MEASURES Description of first aid measures If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. In case of skin contact Wash off with soap and plenty of water. In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. 4.2 Most important symptoms and effects, both acute and delayed To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. 4.3 Indication of immediate medical attention and special treatment needed no data available 5. 5.1 FIRE-FIGHTING MEASURES Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  • 2. 5.2 Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx) 5.3 Precautions for fire-fighters Wear self contained breathing apparatus for fire fighting if necessary. 5.4 Further information no data available 6. 6.1 ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Avoid dust formation. Avoid breathing vapors, mist or gas. 6.2 Environmental precautions Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Sweep up and shovel. Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13. 7. 7.1 HANDLING AND STORAGE Precautions for safe handling Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection. 7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. 7.3 Specific end uses no data available - 858919 8. 8.1 8.2 EXPOSURE CONTROLS/PERSONAL PROTECTION Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls General industrial hygiene practice. Personal protective equipment Eye/face protection Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). 9. 9.1 PHYSICAL AND CHEMICAL PROPERTIES Information on basic physical and chemical properties a) Appearance Form: powder Colour: white b) Odour c) Odour Threshold d) pH no data available no data available no data available
  • 3. e) Melting/freezing point Melting point/range: 223 °C - dec. f) Initial boiling point and no data available boiling range g) Flash point no data available h) Evaporation rate no data available i) Flammability (solid, gas) no data available j) Upper/lower flammability or explosive limits k) Vapour pressure l) Vapour density m) Relative density n) Water solubility no data available no data available no data available no data available no data available - 858919 o) Partition coefficient: noctanol/water p) Autoignition temperature q) Decomposition temperature r) Viscosity no data available s) Explosive properties t) Oxidizing properties 9.2 no data available no data available no data available no data available no data available Other safety information no data available 10. STABILITY AND REACTIVITY 10.1 Reactivity no data available 10.2 Chemical stability no data available 10.3 Possibility of hazardous reactions no data available 10.4 Conditions to avoid no data available 10.5 Incompatible materials Strong oxidizing agents 10.6 Hazardous decomposition products Other decomposition products - no data available 11. TOXICOLOGICAL INFORMATION 11.1 Information on toxicological effects Acute toxicity no data available Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization no data available Germ cell mutagenicity no data available Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available
  • 4. Specific target organ toxicity - repeated exposure no data available - 858919 Aspiration hazard no data available Potential health effects Inhalation May be harmful if inhaled. May cause respiratory tract irritation. Ingestion May be harmful if swallowed. Skin May be harmful if absorbed through skin. May cause skin irritation. Eyes May cause eye irritation. Signs and Symptoms of Exposure To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Additional Information RTECS: Not available 12. ECOLOGICAL INFORMATION 12.1 Toxicity no data available 12.2 Persistence and degradability no data available 12.3 Bioaccumulative potential no data available 12.4 Mobility in soil no data available 12.5 Results of PBT and vPvB assessment no data available 12.6 Other adverse effects no data available 13. DISPOSAL CONSIDERATIONS 13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION 14.1 UN-Number ADR/RID: - IMDG: - IATA: - IMDG: - IATA: - IMDG: - IATA: - IMDG Marine pollutant: no IATA: no 14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods 14.3 Transport hazard class(es) ADR/RID: - 14.4 Packaging group ADR/RID: - 14.5 Environmental hazards ADR/RID: no 14.6 Special precautions for users no data available - 858919 15. REGULATORY INFORMATION This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture no data available 15.2 Chemical Safety Assessment no data available 16. OTHER INFORMATION
  • 5. Further information The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information this document is based on the resent state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. guidechem shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.