The document discusses the shift in healthcare towards outcome-based payment models where pharmaceutical companies are paid based on patient outcomes rather than simply selling pills. It notes that non-adherence to medication is a major issue, with 50% of medicines not taken as prescribed, representing a 36% loss in potential sales. The document then introduces a proposed portable medication adherence device that would keep track of medication intake, assess adherence, and integrate with mobile apps and payers to provide data on outcomes in order to better serve patients and payers. It acknowledges challenges startups face compared to large companies and stresses the importance of innovation, both internal and through external partnerships.

2. Outcome-Based
Payment

3. “We’re paying for the treatment and
patients healed,
not for the pills”
Dr. Paulo Macedo
Minister of Health of Portugal,
talking about the treatment of Hepatitis C

4. “It is okay to be tested on that in the process of price-setting, that is fine, we
should only be paid for the value we bring”
Marijn Dekkers, Bayer’s CEO
on Pharma Times
“I really believe that in the future, companies like Novartis are going to be
paid on patient outcomes as opposed to selling the pill”
Joseph Jimenez, Novartis’ CEO
on Forbes

5. 36%
loss in potential sales
for pharma companies*
*Source: “Patient Adherence: The Next Frontier in Patient Care”, CapGemini
Non-Adherence
50%
medicines not taken
as prescribed*
*Source: “Reviving the Primary Care Market”, IMS Health

6. Look
Beyond the Pill

7. State of the Art
- Hard to set-up
- Expensive
- Designed to control the patient
- Centered in the technology or features
(not in the patient)

9. Good for the Patient
Compact
Portable
Visual and audible alarm
Versatile Interior
Treatment-Specific
Dosage instructions
Can integrate with
mobile app
Keep track of medication
intake

10. Assess medication
adherence
Proximity care
Detect missed doses
Better outcome
Compatible with blisters
(easier with regulators)
Good for Payers

11. Alarm fired at 9:00AM.
Snoozed 3 times. Medicine
taken at 9:55AM.
Alarm fired at 7:00PM.
Medicine not taken.
Data-Rich

12. Low cost per unit
Readily available
technology
Energy efficient
(battery lasts ~8 months)
Inexpensive

13. Easy Integration
adherence
data
Patient Support Program anonymized
report
Pharma
Companies

14. How did we get here?

15. Playing with the Big Guys
€50.000

16. Big vs Small
Big Companies
Regulatory Affairs
Investment Capacity
Market Access
Dealing with Payers
Retain Talent
Startups
Innovating
Ability to Adapt
Flexibility
Disruption
Attract Talent

17. Internal Innovation
External Innovation
Innovation Ecosystem

18. Innovation Ecosystem
Internal Innovation
External Innovation

19. Internal Innovation
External Innovation
Innovation Ecosystem

20. Diogo
CEO
Sofia
Operations
Luís
Software
Joana
Design
Mário
Firmware
Francisco
Hardware
Team

21. Diogo Ortega
diogo@pharmassistant.net
+351 918 491 600
Available for Partnerships