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NATURAL COURSE
OF HIV/AIDS
By
ES NYEMBE
Stage 1 - Primary
• Short, flu-like illness - occurs one to six weeks after
infection

• Mild symptoms
• Infected person can infect other people
Stage 2 - Asymptomatic
Stage 4 - HIV AIDS
 The immune system

weakens too much as CD4
cells decrease in number.
TB & HIV CO-INFECTION
TB is the most common opportunistic infection in HIV and the first cause of
mortality in HIV infected patients (10-30%)
10 million patients co-infected in the world.
Immunosuppression induced by HIV modifies the clinical presentation of
TB :
1.
2.
3.

Subnormal clinical and roentgen presentation
High rate of MDR/XDR
High rate of treatment failure and relapse (5% vs < 1% in HIV)

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Natural course of hiv

  • 2. Stage 1 - Primary • Short, flu-like illness - occurs one to six weeks after infection • Mild symptoms • Infected person can infect other people
  • 3.
  • 4. Stage 2 - Asymptomatic
  • 5.
  • 6. Stage 4 - HIV AIDS  The immune system weakens too much as CD4 cells decrease in number.
  • 7. TB & HIV CO-INFECTION TB is the most common opportunistic infection in HIV and the first cause of mortality in HIV infected patients (10-30%) 10 million patients co-infected in the world. Immunosuppression induced by HIV modifies the clinical presentation of TB : 1. 2. 3. Subnormal clinical and roentgen presentation High rate of MDR/XDR High rate of treatment failure and relapse (5% vs < 1% in HIV)