1. By: Emily Bateman

2. What Are They?
 Adult stem cells (ASC)
are undifferentiated cells
that are in the body after
development.

3. The Two Main Properties Of ASC
 Self-renewal-the ability to go through the cycle of cell
division many times while still keeping its
undifferentiated state
 Multipotency (Multidifferentiative Potential)-the
ability to make offspring of many different cell types.

4. Where Are They Found?
 Any where in the body
but are mostly
extracted from the
blood and bone
marrow.

5. Their Uses In Medicine

6. Degenerative and Debilitating
Conditions Therapy:
 ALS (Amyotrophic Lateral  Kidney Failure
Sclerosis)  Liver Disease
 Alzheimer's Disease  Macular Degeneration
 Autism  Muscular Dystrophy
 Cerebral Palsy  Optic Nerve Injuries
 Degenerative Disc Disease  Parkinson’s Disease
 Erectile Dysfunction  Pulmonary Fibrosis,
 Glaucoma Emphysema, COPD
 Hearing Loss  Retinitis Pigmentosa
 Heart Disease  Spinal Cord Injuries
 Huntington's Disease  Stroke

7. Autoimmune Conditions Therapy:
 Diabetes
 Lupus
 Multiple Sclerosis
 Rheumatoid Arthritis

8. Musculoskeletal Injuries Therapy:
 Knee injuries
 Osteoarthritis
 Torn Ligaments
 Sports Injuries

9. Cosmetic and Dermatologic
Therapy:
 Brazilian Buttock Lifts and Coetaneous Radiation
Treatment
 Breast Augmentation
 Facelift
 Hair Loss

10. The Steps To A Blood (Adult Stem
Cell) Transplant For A leukemia
Patient

11. What Is A Transplant?
 In a bone marrow, or blood
transplant for leukemia you are
getting rid of all the unusual
leukocytes in a patient and are
replacing them with the new
ones

12. History Of ASC Transplants
 In 1968 the first successful bone marrow transplant
took place.
 Bone marrow is transplanted everyday to treat a
variety of blood and bone marrow diseases such as
blood cancers and immune disorders.

13. What Is Leukemia?
 Leukemia is a cancer that affects white blood cells
(leukocytes).
 White blood cells are made by adult stem cells and are
released into the blood stream to fight infections.
 When you have leukemia your white blood cells don’t
grow nor function correctly.
 These cells can no longer fight infections and conflict
with functions of other organs.

14. Step 1: Find A Donor
 Autologous-the donor is also infected person
 Synegenic-the donor is a twin sibling of the infected
person
 Allogeneic-the donor is no related/not closely related
to the infected person
 Cordbold-the donor is an umbilical cord

15. Step 2: Extract the Adult Stem Cells
(They’re In the Blood) From The Donor
 The donor is put on a medication for
four to five days before the transplant
that stimulates the production of
adult stem cells in to the blood
stream.
 Next, the donor must be administered
anesthesia while the healthy blood
cells are collected.

16. Step 3:If It Is An Autologous Donation
 The patient’s blood is
put in a freezer
(apheresis).
 After it is cold, it is
taken in a machine that
confines and kills the
leukemia affected cells.

17. Step 3: If It Is Any Other Donation
 The Blood is frozen until needed.

18. Step 4: “Cleaning The Infected Patient”
 Before the patient receives the unaffected blood he/she
goes through en enduring dose of radiation or
chemotherapy to clear their body of any affected cells.
 Also to make sure every last affected cell is killed, doctors
will put an additional drug in their blood stream to get the
few cells chemo or radiation might have missed.
 This process is called purging.
 If the affected cells are not perfectly removed from the
patient the chances are very high that they will have a
relapse.

19. Step 5: Healing The Infected Patient
 After the patient is “clean”, the new blood is given to
them.

20. Here Is A Video On How
Stem Cells Are Used In Burn
Therapy

22. Works Cited
 "Adult Stem Cell." Wikipedia. Wikimedia Foundation, 18 May 2012. Web. 23
May 2012.
http://en.wikipedia.org/wiki/Adult_stem_cell
 "Frequently Asked Questions." What Are Adult Stem Cells? [Stem Cell
Information]. Web. 23 May 2012.
http://stemcells.nih.gov/info/basics/basics4.asp
 "STEM CELLS IN USE." Stem Cells In Use. Web. 23 May 2012.
http://learn.genetics.utah.edu/content/tech/stemcells/sctoday/
 "Stem Cell Transplant Procedure." Stem Cell Transplant Procedure. Web. 23
May 2012.
http://stem-cell-transplant.info/