28. (a)Capsule may be opened and the contents
taken without crushing or chewing; soft
food such as applesauce or pudding may
facilitate administration; contents may
generally be administered via nasogastric
tube using an appropriate fluid provided
entire contents and washed down the tube.
腸溶衣微粒膠囊(錠劑)：
Bokey… (1)鼻胃管：打開膠囊將完整的顆粒倒入管子內。給藥後以酸性果汁
沖洗。可使用蘋果、小紅莓、葡萄、柳橙、鳳梨、李子、蕃茄等。
(2)鼻腸管：打開膠囊將完整的顆粒倒入管子內。給藥後以鹼性液體
沖洗。如開水、牛奶或鹽水。(藥學雜誌No.90)
29. (b) Liquid dosage forms of the product are
available; however, dose, frequency of
administration and manufacturers may
differ from that of the solid dosage form.
Zinnat…
30. (c) Antacids and/or milk may prematurely
dissolve the coating of the tablet.
Bisacodyl…
31. (d) Capsule may be opened and the liquid
contents removed for administration.
32. (e) The taste of this product in a liquid form
would likely be unacceptable to the patient;
administration via nasogastric tube should
be acceptable.
Colace (docusate): a stool softener
33. (f) Effervescent tablets must be dissolved in the
amount of diluent recommended by the
manufacturer.
K-lyte( potassium bicarbonate and potassium
citrate )
• Do not chew the effervescent tablet or swallow it
whole.
• Drop the tablet into a glass and add at least 4 ounces
(one-half cup) of cold water or fruit juice. When the
tablet has completely dissolved, begin drinking the
mixture slowly, over 5 to 10 minutes in all.
34. (g) Tablets are made to disintegrate under the
tongue.
Nitrostat(Nitroglycerin)
35. (h) Tablet is scored and may be broken in half
without affecting release characteristics.
Isoptin SR(verapamil)
36. (i) Skin contact may enhance tumor
production; avoid direct contact.
Cellcept(mycophenolate)(山喜多)
整粒吞服，不可打開膠囊
免疫抑制劑;致畸性
40. 參考資料
• Oral dosage forms that should not be crashed John F.
Mitchell (ISMP)
• Treatment Standards for ADHD: Achieving Optimal
Benefit. Peter S. Jensen, MD
• 北醫藥訊40期
• Blog 快樂小藥師
• 藥學雜誌90期
• Eric S. Rovner, Alan J.Wein: Once-daily Extended-
Release Formulations of Antimuscarinic Agents in
the Treatment of overactive Bladder. European
Urology 2002; 41: 6-14.
