Introduction new ppt!

Synthesis of (±) - Linezolid Abhijeet Patil. M.Sc. Chemistry. Fergusson College, Pune.

INTRODUCTION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical Applications of Linezolid ,[object Object],[object Object],[object Object],[object Object]

Synthesis of (±) – Linezolid: Scheme

Synthesis: 3-Fluoro-4-morpholinylnitrobenzene

Synthesis: 3-Fluoro-4-morpholinylaniline

Synthesis: N-Carboethoxy-3-fluoro-4-morpholinylaniline

Synthesis: Ethyl N-allyl N-(3-fluoro-4-morpholinophenyl) carbamate

Synthesis: 5-(Iodomethyl)-3-(4-morpholinophenyl) oxazolidin-2-one The obtained iodolactone was unstable.

Synthesis: [N-3-(3-Fluoro-4-morphylinyl phenyl)-2-oxo-5-oxazolidinyl] methyl azide

CONCLUSION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

REFERENCES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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THANK YOU ,[object Object],[object Object],[object Object],[object Object]

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