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Immunopharmacology

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IMMUNOPHARMACOLOGY Ma. Janetth B. Serrano, M.D., DPBA
IMMUNOPHARMACOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
IMMUNOPHARMACOLOGY 0psonized bacteria Macrophage APC T lymphocyte IL-2 IL-2 IFN-  Activated Macrophage Activated NK cells Activated Cytotoxic T cell CELL-MEDIATED IMMUNITY B lymphocyte IL-4,IL-5 TH 1 TH 2 Memory B Cells ,[object Object],[object Object],[object Object],HUMORAL IMMUNITY IFN-  TNF-  IFN- 
[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Immunosuppressants IMMUNOPHARMACOLOGY
Corticosteroids IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Corticosteroids IMMUNOPHARMACOLOGY
Cyclosporin IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Cyclosporin IMMUNOPHARMACOLOGY
Tacrolimus IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Tacrolimus IMMUNOPHARMACOLOGY
Sirolimus (rapamycin) IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Sirolimus (rapamycin) IMMUNOPHARMACOLOGY
Interferons IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Interferons IMMUNOPHARMACOLOGY
TNF- α binding drugs IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
TNF- α binding drugs IMMUNOPHARMACOLOGY
Mycophenolate Mofetil IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Mycophenolate Mofetil IMMUNOPHARMACOLOGY
15-Deoxyspergualin IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
15-Deoxyspergualin IMMUNOPHARMACOLOGY
Thalidomide IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Thalidomide IMMUNOPHARMACOLOGY
Glatiramer IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Glatiramer IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY CYTOTOXIC Agents:
Azathioprine IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Azathioprine IMMUNOPHARMACOLOGY
Leflunomide IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Leflunomide IMMUNOPHARMACOLOGY
Cyclophosphamide IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Cyclophosphamide IMMUNOPHARMACOLOGY
Antibodies as Immunosuppressive Agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY MONOCLONAL ANTIBODIES :
Muromonab-CD3 IMMUNOPHARMACOLOGY
[object Object],[object Object],IMMUNOPHARMACOLOGY Muromonab-CD3
Muromonab-CD3 IMMUNOPHARMACOLOGY
[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY MONOCLONAL ANTIBODIES :
[object Object],[object Object],[object Object],IMMUNOPHARMACOLOGY
Interferon-alpha
IMMUNOMODULATORS ,[object Object],- hairy cell leukemia - chronic myelogenous leukemia - malignant melanoma - Kaposi’s sarcoma - anticancer  renal cell CA, carcinoid syndrome, T cell leukemia
Interferon-alpha
IMMUNOMODULATORS ,[object Object],GM-CSF Interferons & IL-2 TNF-alpha Interleukin-2 Interferon-gamma Interferon-beta
IMMUNOMODULATORS ,[object Object],Melanoma and Prostate cancer (+) effects in response to Hep B vaccine Malignant melanoma Soft tissue sarcoma of extremities Metastatic renal cell CA Malignant melanoma Chronic granulomatous disease Relapsing type multiple sclerosis
IMMUNOMODULATORS ,[object Object],GM-CSF Interferons & IL-2 TNF-alpha Interleukin-2 Interferon-gamma Interferon-beta
LEVAMISOLE IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY
IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY - antiparasitic agent - potentiate action of fluorouracil in adjuvant therapy of Dukes class C colorectal CA - other uses: > hodgkin’s lymphoma > RA
LEVAMISOLE IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY
BCG (Bacille-Camille-Guarin) IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY
IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY - immunization against tuberculosis - Adjuvant in intravesical therapy for SF bladder CA
BCG (Bacille-Camille-Guarin) IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY
IMMUNOPHARMACOLOGY IMMUNOMODULATORS IMMUNOPHARMACOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object]

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