Amyloidosis and porphyria

DAPM RV DENTAL COLLEGE DEPARTMENT OF ORAL AND MAXILLOFACIAL PATHOLOGY

REFERENCES ,[object Object],[object Object],[object Object],[object Object]

REFERENCES ,[object Object],[object Object],[object Object],[object Object],[object Object]

AMYLOIDOSIS ,[object Object],[object Object],[object Object],[object Object]

AMYLOIDOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object]

COMPOSITION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

CHEMICAL NATURE OF AMYLOID ,[object Object],[object Object],[object Object]

AL( Amyloid light chain ) PROTEIN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

AA (Amyloid associated) Protein ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Amyloid fibril structure obtained by cryo-electron microscopy with a cross-β structure modeled into the electron density map based on J.L. Jimenez et al., EMBO J , 18: 815–21, 1999

AMYLOIDOSIS OF KIDNEY SOURCE: Pathologic outlines.com

AMYLOIDOSIS OF HEART SOURCE: Pathologic outlines.com

SAGO SPLEEN SOURCE: Altas of pathology

LARDACEOUS SPLEEN SOURCE: Altas of pathology

PRIMARY and MYELOMA ASSOCIATED ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

PRIMARY and MYELOMA ASSOCIATED ,[object Object],[object Object],[object Object],[object Object],[object Object]

Nodularity and ulceration of the tongue. Color atlas of Dental Medicine- Oral Pathology

Primary systemic amyloidosis: deep red nodules on the lips. Google images

Primary systemic amyloidosis: macroglossia, ecchymoses on the tongue. Google images

Patient exhibits a firm, waxy, smooth lesion near the eye. Google images

PRIMARY and MYELOMA ASSOCIATED ,[object Object],[object Object]

SECONDARY AMYLOIDOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object]

HEMODIALYSIS ASSOCIATED AMYLOIDOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object]

HEREDOFAMILIAL AMYLOIDOSIS ,[object Object],[object Object],[object Object],[object Object]

Haematoxylin and Eosin ,[object Object],[object Object],[object Object],[object Object],[object Object]

IODINE STAIN ,[object Object],[object Object],[object Object],[object Object],[object Object]

CONGO RED ,[object Object],[object Object],[object Object],[object Object]

METACHROMATIC STAIN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

FLUORESCENT STAINS ,[object Object],[object Object],[object Object]

DIAGNOSIS ,[object Object],[object Object],[object Object],[object Object]

TREATMENT AND PROGNOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object]

INTRODUCTION ,[object Object],[object Object]

HEPATIC TYPE ,[object Object],[object Object]

ACUTE INTERMITTENT PORPHYRIA ,[object Object],[object Object],[object Object],[object Object]

HEREDITARY COPORPHYRIA ,[object Object],[object Object],[object Object],[object Object]

VARIGATE PORPHYRIA ,[object Object],[object Object],[object Object],[object Object]

PORPHYRIA CUTANEA TARDA ,[object Object],[object Object],[object Object]

ERYTHROPOIETIC PORPHYRIA ,[object Object],[object Object],[object Object]

ERYTHROPOIETIC PROTOPORPHYRIA ,[object Object],[object Object],[object Object],[object Object]

CONGENITAL ERYTHROPIETIC PORPHYRIA ,[object Object],[object Object],[object Object],[object Object],[object Object]

CLINICAL FEATURES ,[object Object],[object Object],[object Object],[object Object]

ORAL MANIFESTATIONS ,[object Object],[object Object],[object Object]

TREATMENT ,[object Object],[object Object]

Amyloidosis and porphyria

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Amyloidosis and porphyria