Poster presented at Nanoinformatics 2011. It describes the work being done at the UCLA Center for Environmental Implications of Nanotechnology

1. Nanoinformatics Collaboration, Data Management
and Analysis Tools for Nanomaterial Characterization,
Toxicity and Environmental Distribution
Yoram Cohen1,2, Taimur Hassan1, Rong Liu1,2
Approach
Web-based data and project management, research collaboration, data mining and tools for nanomaterial hazard ranking,
transport and fate, exposure, toxicity and environmental impact analysis
Data Management Resource and Communication Management
• Metadata enabled • Accessible by Reports and Forms Personal Profiles
• Nanomaterials database Metadata Enhanced Data Repository researchers and
• Enhanced file search capability Document Retrieval administrators
• Workflows for uploading, • External nanoparticle
reviewing and approving data resource directory
documents • Annual and quarterly
• Data archiving and retrieval reports Online quarterly report
• Personal online submission and project Personal web space
NanoCatalog space status overviews for CEIN members
• Newsletters
• Event, Media and Events & Newsletters Online Courses
• Central storage of CEIN data files
Calendaring
• Metadata replaces need for subfolder structures • Help files and videos
• A context menu allows access to various functions
(e.g., editing/viewing file metadata properties and
• Online CEIN nanoparticles library • Search engine that can access metadata version controls for check-in and check-out of files)
• Web-based checking of • Capable of processing custom crawl rules • Dynamic search report generation
nanomaterials availability and • Content-based search of repository files How-to guides and Nanotoxicology lectures
request of samples nanomaterial discussions for distance learning
Web-Based Analysis Tools
Modeling of Nanoparticles Distribution High Throughput Analysis Tool NanoCrawler
• Predict concentrations of
nanoparticles in various Extensible:
Programmable and
environmental media
• Web Services and Web Parts  Support for
• Graphical Interfacecustom web applications via C#
third-party and for
parameter input
and Visual Basic
• “What-if” scenarios SharePoint components
• Access to useful
analysis
• Custom applications have been authored for
bulk file management, report generation and
password reset
• Real-time
visualization • Rapid analysis and visualization of HTS data
of simulation • Standardized HTS plate format
results • Various algorithms for outliers removal, data • Integrates data files stored within the CEIN data repository
• Capability for normalization and hit identification with the NanoCatalog (i.e., nanoparticles library)
creation of user • Visualization of HTS data analysis in terms of • Files can be filtered based on multiple criteria
scenario library heatmaps and self organizing maps • Information specific to data files can be dynamically sorted and reports
and simulation • CEIN data files are directly accessible and analysis generated based on metadata (e.g. particle type, experiment type,
results results stored on remote server experimental conditions, particle properties)
1 UC Center for the Environmental Implications of Nanotechnology (UC CEIN), University of The UC Center for Environmental Implications of Nanotechnology (UC CEIN) at UC Los Angeles (UCLA) is in partnership with UC Santa Barbara (UCSB), UC Davis (UCD), UC Riverside (UCR), Columbia University in New York, the Molecular Foundry at Lawrence Berkeley National Laboratory
California Los Angeles, 6522 CNSI, 570 Westwood Plaza, Los Angeles, CA 90095-7277. (LBNL), the Lawrence Livermore National Laboratory (LLNL), Nanyang Technological University in Singapore (NTU), University of New Mexico (UNM), Sandia National Laboratory (SNL), University of Texas in El Paso (UTEP), University of Bremen (Germany), University of British Columbia (UBC),
2 Department of Chemical and Biomolecular Engineering, 5531 Boelter Hall, University of Cardiff University (Wales), University College Dublin (UCD, Ireland), and Universitat Rovira i Virgili in Spain (URV).
California Los Angeles, Los Angeles, California, USA