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ZRANB2

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rpg7ss

Talk given at the MRC-LMB, Cambridge on 29 Aug 08

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ZRANB2 — a transcriptional regulator? Richard P. Grant MMB, Sydney Thursday, 11 September 2008 1
Splicing • Splicing ubiquitous in eukaryotes • ~70% human genes are alternatively spliced • Aberrant splicing causes genetic disease, e.g. - DMD - CF Thursday, 11 September 2008 2
Consensus sequences direct splicing Exon 1 Intron 1–2 Exon 2 Thursday, 11 September 2008 3
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ZRANB2

  • 1. ZRANB2 — a transcriptional regulator? Richard P. Grant MMB, Sydney Thursday, 11 September 2008 1
  • 2. Splicing • Splicing ubiquitous in eukaryotes • ~70% human genes are alternatively spliced • Aberrant splicing causes genetic disease, e.g. - DMD - CF Thursday, 11 September 2008 2
  • 3. Consensus sequences direct splicing Exon 1 Intron 1–2 Exon 2 Thursday, 11 September 2008 3