Nine sigma grand challenges

GRAND CHALLENGES
ACHIEVE HIGH IMPACT OUTCOMES THROUGH FULLY MANAGED
GRAND CHALLENGES

Rick Wielens CEO Ninesigma Europe

Copyright 2013, NineSigma

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WHAT IS NINESIGMA‟S GRAND CHALLENGE?

A LARGE SCALE TECHNOLOGY SEARCH THAT
ENGAGES TECHNICAL AND STAKEHOLDER
COMMUNITIES TO IDENTIFY TRANSFORMATIVE
TECHNOLOGY DEVELOPMENT OPPORTUNITIES


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NINESIGMA OVERVIEW

OFFICES IN
USA, EUROPE, JAPAN, AUSTRALIA,
KOREA AND CANADA

37,000 + PROPOSALS
RECEIVED FROM 116 COUNTRIES

2,500 + OPEN INNOVATION
PROJECTS COMPLETED

DIVERSE CLIENTS
MULTINATIONALS, MIDDLE
MARKET, NONPROFIT, GOVERNMENT

2 MILLION + SOLUTION
PROVIDERS CONTACTED

PROGRAM MANAGER
EXPERIENCE: 28 YEARS AVERAGE
INDUSTRY EXPERTISE, 150
PROJECTS MANAGED

WE HAVE IDENTIFIED SOLUTIONS IN EVERY
MAJOR INDUSTRY AND TECHNICAL AREA

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OUR GLOBAL TECHNOLOGY NETWORK GROWS
WITH EVERY CHALLENGE

Over 2 million
solution
providers


Industry
Academia
Labs & Institutes
Inventors

Continually
expanding
network

Providers in
virtually every
country

Viral networking
extends our
reach further

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GRAND CHALLENGE APPROACH
OUR DEEP EXPERIENCE ENABLES YOU TO ACHIEVE
YOUR KEY OBJECTIVES QUICKLY AND EFFICIENTLY

Unite diverse Sponsors to develop a
cohesive message and integrated goals

Grand Challenge teams with Program
Management and Technical Managers

Complete management of full
program execution

NineSigma‟s marketing team
complements your marketing program


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WHAT ARE THE ELEMENTS OF SUCCESS?

DUAL “CALL TO ACTION” STIMULATES
TECHNOLOGY EXPERTS & STAKEHOLDERS

INCENTIVES MOTIVATE PARTICIPANTS
AND MAXIMIZE STAKEHOLDER FOCUS

DUAL OUTREACH INCLUDES TECHNICAL
CAMPAIGNS + PR/MARKETING

JUDGING PANEL AND PROCESS
AFFIRM CREDIBILITY AND COMMITMENT

CLEARLY DEFINED TECHNOLOGY
OBJECTIVES ARE RESULTSFOCUSED, ACHIEVABLE, AND TIME-BOUND

NINESIGHTS COLLABORATION PLATFORM
IS THE GRAND CHALLENGE HUB

MANAGING THE COMPLEXITY OF GRAND CHALLENGES
IS NINESIGMA‟S CORE COMPETENCY

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DUAL OUTREACH + CALL TO ACTION

BREAKTHROUGH INNOVATION
GRAND CHALLENGE

Research centers
Corporations
Universities

Suppliers
Start up/
Entrepreneurs


IDENTIFY
SOLUTIONS
Technical
Outreach

MESSAGE,
CAMPAIGN
& PRIZE
STRATEGY

PR
OUTREACH

The “Public”
Customers
Industry

Catalyst to
Stakeholders

Advocates
Government/
Military
NGOs

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WHAT CAN BE ACHIEVED WITH A
GRAND CHALLENGE?
Identify breakthrough, transformative solutions to a complex,
interdisciplinary challenge
Establish the Sponsors as leaders in their industry
Enhance public perception of the Sponsors
Demonstrate the power of uniting diverse Sponsors


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PROGRAM METHODOLOGY

Phase 1

Phase 2

PROGRAM DESIGN
Month 1-3

SUBMISSION PERIOD
Months 4-6

Phase 3
CLOSE AND ASSESS
Month 7-9

Phase 4
AWARD STAGE
Month 10-12

OUTREACH STRATEGY DEVELOPMENT
Identify Targets

Email campaign

Solution provider communication
PR and Advertising

NOTE: Actual timelines depend on program scope and Sponsor goals


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OUR HOLISTIC APPROACH
WE TRANSLATE EACH SPONSOR’S OBJECTIVE INTO AN
INTEGRATED TOPIC AND PRIZE STRATEGY
GOALS

OUTCOMES

STRATEGY
Technical outreach
to Solution Provider
Network
• Multiple

Vision

challenges

Visionary

• New

players

• Technology

focus
• Target

CAMPAIGN &
PRIZE STRATEGY

• Accelerated

• Phased

development

awards
• Diverse

stakeholders

judging
committee

Objectives

• Short &

Prize awards

long term
opportunities

Marketing outreach
to Stakeholder
Community


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GRAND CHALLENGE

HEAD HEALTH CHALLENGE

OVERVIEW & CHALLENGES
• The GE NFL Head Health Grand Challenge is a $60 million program that
includes research and challenges to develop new solutions to help
advance understanding of mild traumatic brain injury.
• The first $10 million Challenge invites proposals for scanning
technologies and biomarkers.
• A second $10 million Challenge with Under Armour launches Fall 2013 to
find, fund, and develop new solutions to diagnose and protect against
traumatic brain injury

APPROACH
• Because GE and the NFL bring distinct resources to their
partnership, NineSigma worked closely with GE and the NFL to align
their goals and design a challenge program that would achieve each of
their objectives
• With two challenge topics, and a diverse judging panel, the prize
strategy was a critical component that had to be defined and clearly
communicated to a broad technical and consumer audience

KEY TAKEAWAYS
• Translating each Sponsor‟s objective into an integrated topic
and prize strategy is a critical first step which determines the
success of the program
• Even a large scale, multi-year Challenge such as this can be
defined, scoped and launched in a short period of time when
there is executive buy-in and support


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GRAND CHALLENGE

NEW CARBON-BASED PRODUCTS & MARKETS

• Climate Change and Emissions Management (CCEMC) Corporation had
been actively running challenges to address incremental advances.

• CCEMC wanted to „elevate the discussion‟ and search for breakthrough
innovation; the Grand Challenge allowed them to do that.

• Grand Challenge is expected to identify multiple technologies that will
provide significant reductions in greenhouse gas emissions by
transforming carbon from a liability into an asset.

APPROACH
• NineSigma worked with CCEMC and its Board to define goals, hone in
on the need, and align all stakeholders around a common vision.
• NineSigma coordinated all aspects of Grand Challenge
messaging, PR, and outreach, coordinating with CCEMC and its
marketing agency partner.

KEY TAKEAWAYS
• Working with an organization that does not have in-house
technical leadership requires a different
approach, particularly in the discovery & strategy phase.
• Alignment around issues like prize strategy, confidentiality
and PR is critical when multiple stakeholders are involved.


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GRAND CHALLENGE

ASSEMBLING TOOLS TO FIGHT
BREAST CANCER

• Aspiration: To fight breast cancer.
• Challenge focused on mapping breast cancer
pathways, specifically to map the molecular/proteomic similarities
between breast cancer and other solid tumors.
• The Challenge was receiving low results and the quantity and
quality of proposals needed to increase.

RESULTS
• NineSigma was brought after Challenge launch and activated best
practices including outreach to broad technical and non-technical
audiences and a detailed communications strategy to ensure
challenge success.
• Ultimately over 500 proposals were received from 40 countries.
• Five winners were selected: each received $100k seed award in
addition to support through mentorships and access to GE
researchers and industry thought leaders.

“It is often challenging for early stage research to
grab the attention of seed investors. The challenge
has shown us that there are a remarkable number
of breakthrough ideas out there that deserve
promotion, investment and incubation.”

KEY TAKEAWAYS
• The right access to technical communities is key. In
addition there are fundamentals that must be followed —
including activities before, during and after the challenge.

— BETH COMSTOCK
CHIEF MARKETING OFFICER


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GRAND CHALLENGE

PROTEIN STABILIZATION FOR AN
EFFECTIVE AIDS VACCINE

• Each day, 7,400 individuals worldwide are newly infected with HIV. This is
one of the greatest medical challenges of the 21st century. IAVI has
focused on AIDS vaccine development for over 10 years.
• Breakthrough discovery: Naturally occurring antibodies neutralize proteins
on the surface of the virus, “disarming” the HIV, but the protein is too
unstable to be effectively targeted and needs to be stabilized.
• IAVI previously ran a search which focused on vaccine specialists only and
didn‟t receive any solutions of value.

RESULTS
• NineSigma identified the challenge as a protein “stabilization” problem, and
more than 30 proposals were submitted from protein researchers globally.
• A result of the quality and volume of responses, IAVI was able to go secure
additional funding from the Gates Foundation.

“NineSigma provided a number of promising new
approaches to protein stabilization that we had not
previously explored. We are confident that the
researchers they helped identify have much to
contribute to the development of an effective AIDS
vaccine.”
— WAYNE KOFF
CHIEF SCIENTIFIC OFFICER
OF IAVI


• The search identified two scientists initially and eventually a third who will
receive a total of $875K to develop solutions for generating stable protein
complexes for use in AIDS vaccines.

KEY TAKEAWAYS
• Defining the problem differently opened up a new audience.
• NineSigma didn‟t go to the „usual suspects‟ — as a result, a
wealth of valuable proposals was generated.

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GRAND CHALLENGE

INNOVATIVE ENERGY TECHNOLOGIES

• Current energy production methods are not sustainable to meet growing
global demand for affordable, reliable and accessible energy.
• LAUNCH was seeking breakthroughs in: energy efficiency, equitable
access, reduced GHGs, increased reliability, reduced cost, reduced
negative impact on human health and the environment, and positive
impact on living standards.

RESULTS
• NineSigma targeted public and private sector energy specialists plus
financial experts in modeling and private institutions.
• More than 160 proposals were submitted.
• 10 “Game Changing” solutions were selected including technologies like
prepaid electric storage units for rural areas.
• Winners received mentoring and access to new business
partners, government and potential funding sources.

KEY TAKEAWAYS
• The Grand Challenge addressed the goals of multiple
stakeholders including government and industry.
• The Challenge topic was broad yet also clearly defined the
need and criteria for solutions being sought which enabled a
high volume of quality proposals.


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GRAND CHALLENGE

SUSTAINABLE PACKAGING FOR
MICRONUTRIENT POWDERS

• Scientists Without Borders, Sackler Institute at the New York Academy of
Sciences, and Sight and Life were seeking sustainable and effective
approaches for delivering micronutrient powders (MNPs).
• MNPs are a critical tool in tackling global malnutrition.

• Current MNP packaging cannot be recycled, re-purposed, burned, or
composted creating large amounts of waste.

RESULTS
• 36 proposals were received from 15 countries over 90 days.
• One-third of the submissions were from solvers in developing countries.
• Scientists Without Borders selected three winners with solutions
involving: double-sack packaging, repurposing condiment
packaging, and the use of Chitosan setting solution.

KEY TAKEAWAYS
• The Challenge topic motivated solution providers, even
though the prize was modest ($25K)
• Engaging the right packaging and material
science, communities produced high quality outcomes


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