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Flanders as a creative innovative region



  Leuven, a region for
innovation & high-tech
   entrepreneurship

              Dr Martin Hinoul
     Business Development Manager KU Leuven

           Leuven , December 12, 2012
M.Hinoul
From a Globe to a Flat World




                                Source:Awex




For thousands of years we were living on a globe where
          innovation was a very slow process


                                                    M.Hinoul
SIR* World Report 2012


                                                                INDICATORS
                                                                • Output
                                                                • International Collaboration
                                                                • Normalized Impact
                                                                • High Quality Publications
                                                                • Specialization Index (Gini
                                                                  index)
                                                                • Excellence Rate


• 3290 Research Institutions (strong criteria)
• more than 80% of the world scientific output (2006-2010)
 (Global Ranking KU Leuven 68 – (universities 32) - European Ranking KU Leuven 5)

*Scimago Institutions Rankings
                                                                                      M.Hinoul
World’s GDP and R&D Budgets !


                                          1,74 tr $

   16,5 tr $               18 tr $                        6,4 tr
                                                            $         5 tr $
  2,8% R&D               2% R&D
                                               1,5 tr $



               2 tr $




                 Source : The World Bank-Reshaping Economic Geography, Hinoul

                                                                                M.Hinoul
The Economist Intelligence Unit Limited
              (Dec. 2011)
   There are few economic policies as popular as research
    parks, incubators and clusters –very hot today.
   It is hard today to find a country, region, or even a city
    that is not trying to develop a network of competitive
    firms (clusters)
   The “political appeal” is therefore obvious, particularly
    now that the world’s economic crisis has put a spotlight
    on “innovation” to diversify economies and create jobs
   However the difficulty lies in turning these “science
    parks”, incubators or “hi-tech”corridors into success
    stories. Not so simple.
                                                                 M.Hinoul
Globally there are more than
       1400 cluster initiatives
   Hollywood


   Bordeaux


   New York & London financial services


   Silicon Valley


   San Diego – Biotech Triangle


   Cambridge Phenomenon                   M.Hinoul
World’s Knowledge 2012 and formation of
      knowledge economy regions




                                      M.Hinoul
Indeed formation of Knowledge Economy
               Regions




                                    M.Hinoul
Globally there are more than 50 well
developed knowledge economy regions




                               Source : Vacature – M.Hinoul



                                                    M.Hinoul
Source : Harvard Business Review July-August2012 – p.26
                                                M.Hinoul
Leuven, a region for
innovation & high-tech
   entrepreneurship



                         M.Hinoul
The Leuven Region
 Close to Brussels

                              Leuven Region: 95.000 habitants




                    Airport   Leuven
         Brussels




                                                      M.Hinoul
An old young city




                    M.Hinoul
Leuven, a region for innovation &
      high-tech entrepreneurship
   Leuven provides the key ingredients for innovation and high-tech
    entrepreneurship:
       Cutting-edge science & technologies
       A long tradition of technology transfer (40 years)
       An innovative business climate with many high-tech companies and state-of-the-
        art incubators & science parks
       Investment capital
       People & networking opportunities
       International affiliations
       Collaboration with Mayor of Leuven




                                                                                   M.Hinoul
Knowledge institutes
   K.U.Leuven Association
   Leuven University Hospitals
   imec
   VIB departments

      Combined R&D budget of 664 million € (KU Leuven and Imec)
      Employ about 19,500 people (6,400 researchers)
      Huge inflow of knowledge and innovative ideas
      Attractive location for high-tech companies
      High-tech ecosystem




                                                                   M.Hinoul
Facts & Figures
1. Students                                              3. Research
 • 40.257 students : 21. 927 f                             • Researchers (fte)
                     18. 204 m                                  • Professors 1018 (12% international)
 • 45% Bachelor                                                 • Postdocs 1052 (36% international)
   31% Master                                                   • Doctorandi 4381 (38% international)
   5% Master-after-master
                                                           • R&D Budget
   11% Doctor program
   1% Teachers education                                     364 million Euro (2011)
   7% others                                                     • 5199 publications (in 2010)
                                                                 • 625 doctors (in 2010-2011)
 • 6. 248 International students : - 3.204 EU students           • 98 spin-off companies (2011)
                                   - 3.017 others



2. Education                                             4.Personnel KU Leuven
    • Dutch language programs                             18.635 people
          • 55 bachelor                                     • 9.971 at the university
          • 132 master                                      • 8.664 at the University Hospitals
          • 53 master-after-master - programs
    • International language :
          • 47 master
          • 31 master after master
          • 2 bachelor – programs in English




                                                                                                   M.Hinoul
Students KU Leuven ( 2011 – 2012)


                         Total 40.257
   Law / Economy            8.741       21,7 %
Sciences / Engineering      8.844       22,0 %
 Medical / Pharmacy         7.974       19,8 %
     Languages              4.572       11,4%
        Other              10.126       25,2%




                                                 M.Hinoul
University Leuven                      IMEC
                                                                   Knowledge Centers

                664 mi€ R&D, 6400 Researchers

                300 Technology Cies, 135 spin offs                 High Tech Industrie


Life Sciences   Nanotechnology      Mechatronics      Cleantech          Clusters



                                                                   Technology Platforms


  Haasrode      Arenberg   Leuven Noord   Genk THOR   Tienen FFH     Research Parks



                                                                        Networks


                                                                                    M.Hinoul
Leuven, specialising in four
            technology domains
•   Life sciences
•   Nanotechnology
•   Mechatronics & smart systems
•   Cleantech




                         © imec



                                        M.Hinoul
Transfer Cell
K.U.Leuven R&D




                  M.Hinoul
K.U.Leuven Research & Development received the
                     2008 IPTEC Tech Transfer Award
             Nominated:

                •K.U.Leuven R&D (Winner 2008)
                •Columbia University (USA)
                •Imperial Innovations (UK)
                •MIT (USA)
                •Wisconsin Alumni Research Foundation (USA)
             Received the award :
                •2006 : Stanford University (USA)
                •2007 : Tsinghua University (China)


                                                              M.Hinoul
© 2007 LRD
What is LRD?

•   Founded in 1972 (40 years young this year)
•   Technology and knowledge transfer office of K.U.Leuven
•   Bridge between university, industry and society
•   Supports researchers
•   Offers technologies to industry
•   Large budgetary and HR autonomy
•   ‘Business unit’




                                                             M.Hinoul
K.U.Leuven: Organisation

•   K.U.Leuven   Education Policy

                 Research Policy

                       DOC: Research Coördination

                        K.U.Leuven R&D: valorisation

                              Professional Support

                              Research Divisions


                 Faculties

                        Departments

                              Research Projects
                                                       M.Hinoul
What do we do?

•   Research collaboration
•   Protection and exploitation of intellectual property
•   Spin-off creation & innovation
•   Support of regional development
•   Stimulation of entrepreneurship through network initiatives




                                                          M.Hinoul
Research collaboration

• Oldest activity of LRD
• Performing research & services for companies or
  governments
• What do we do?
   –   Creating awareness and transferring knowledge
   –   Providing advice
   –   Negotiating contracts
   –   Following up on contracts
   –   Managing research files financially
   –   Offering administrative support
   –   Preparing legal documents


                                                       M.Hinoul
Contract Research

        € 160.000
thousands




                                                                                         160.000

        € 140.000                                                              144.802



        € 120.000                                                    126.807
                                                           121.653


        € 100.000
                                                  97.844

                                         87.908
            € 80.000


                                70.193
            € 60.000

                       54.332
            € 40.000



            € 20.000



                 €0
                       2004     2005     2006     2007      2008      2009      2010      2011




                                                                                         M.Hinoul
Intellectual property
• What do we do?
  – Creating awareness and transferring knowledge
  – Assessing the feasibility, patentability and market potential of
    an invention
  – Determining a protection strategy
  – Drafting and filing a patent application
  – Following up on patent procedures and costs
  – Negotiating and drafting NDA’s, MTA’s and license
    agreements
  – Finding industrial partners




                                                                       M.Hinoul
Spin-offs & innovation

• What do we do?
  – Developing business plans
  – Validating business models and
    the market
  – Offering legal support
  – Putting together a competent team
  – Finding investors
  – Finding infrastructure
  – Growth management
  – Promoting valorisation and entrepreneurship
  – Stimulating regional development, networks and clusters



                                                              M.Hinoul
Spin-offs & innovation

•   Gemma Frisius Fund K.U.Leuven (GFF)
    – Seed capital for spin-off companies
    – GFF founded in 1997 & GFF II in 2002
        •   At the end of 2009 GFF and GFF II merged into one
            single fund
    – Partners:
        •   K.U.Leuven (20% of capital)
        •   Two banks: KBC Private Equity (40%) en
            Fortis Private Equity (40%)
    – Combination between:
        •   Research and technology transfer expertise (university)
        •   Financial expertise (financial partners)
    – Not restricted to a specific technology domain
    – 24.9 million euro capital (22.9 million invested, 28 companies)
                                                                      M.Hinoul
K.U.Leuven Spin offs


100

 90

 80

 70
                                              Gemma Frisius-Seed Capital
 60                                           2x 12,5 m€

 50

 40

 30

 20

 10

  0
  1980   1982   1984   1986   1988   1990   1992   1994   1996   1998   2000   2002   2004   2006   2008   2010   2012




                                                                                                            M.Hinoul
Spillovers and multipliers

• Multipliers --- spin-offs, 2006 - 2010:
   – K.U.Leuven direct investments: 4,7 M€
   – (Gemma Frisius Fund investments: 12 M€)
   – Other third party investments: 476 M€


• Patent portfolios:
   – K.U.Leuven R&D, 454 active patent families of which 90%
     economically exploited
   – Multiplier effects of patent portfolios of spin-off companies 
     sectoral multipliers of 3-to-4




                                                                   M.Hinoul
Creating leverage




                    M.Hinoul
Capital Markets
    Other capital markets
       IT- Partners, Fortis Private Equity, KBC Investco
       Stockmarket
         Ubizen
         ICOS
         Option
         Telindus
         Quest for Growth
         OMS
         Thrombogenics (1,4Bi Euro)
         Metris
         Tigenix
         …..


                                                            M.Hinoul
Micro-elektronica - nanotechnologie
  Kenniscentra
                                                               Eyetronics
                                                                                   Telindus
                                                B.E.S.T.

                                                                Newfrom                 Tyco Electronics
  Centers of                   A.C.S. Belgium
                                                       Resonext    Option International
                                                                                   Cypress Semi
  excellence                                   Eonic Systems         ARM                                       Luciad
                                                                                         FillFactory
                        Assurcard        Vivactiss
                                                                   K.U.Leuven                    STM
                                  ICOS Vision           Lab Photochemistry & Spectroscopy                         Tomoton
                                    Systems            Lab of Solid-state Physics & Magnetism Agilent Techn.
                               JSR Electronics
                                                                                                  J.W.Lemmens
                              Vector International                 KULeuven                                        Micro Matic
                      IPCOS                                          IMEC
                                 Photovoltec                                                       Philips ITCL

                                    Xenics                           IMEC                         Septentrio
                                                            Sub-45nm research facility
                                                                                                                  Delcomp
                                      Oligosense            Nanotechnology Platform
  Pure innovatieve                                               Design platform
                                                                                              ASM Belgium
                         Krypton         Epiq Sensor Nite
  bedrijven                                                                   Target Compiler Techn.           Data4S
                                                Soltech        AnSem
                                                                                Easics
                                                                       CoWare
  Mixed innovatieve                                                                      Mind Linux
                                                 LMS
  bedrijven                                                                              Solutions


                                                                                                                        M.Hinoul
Mechatronica
Kenniscentra                                                       Stas
                                                                                   Alnaco
                                       Ora Machines     B.E.S.T.

                                                                    Optidrive
Centers of                   ACE Electronics
                                           WTCM         Air Beraing Prec. Techn.
excellence                                      Barco Aarschot              Electrical & Mech. Design   Donaldson
                                                                             DV Consulting IPCOS
                        Partec Eng       Materialise
                                                                   K.U.Leuven                 Krypton
                                                                 Dept. Mechanics                           Dynamotor
                                                                 Researh groups                             Decoster
                                                                                            Luyten Automation
                                      Metris
                                     Somatech
                                                                   KULeuven
                       SST
                    Food Mach Atos Engineering                                                     PEC EME

                                                                 K.U.Leuven
                     Camco                                                                  Entecom Systems
                                                         Dept of Metall. & Mater. Eng                      Tecmate
                     Techn                                 Lab Agric Mach & Proc
Pure innovatieve                                                                                             Intl.
                          Flexlink       D2S International
bedrijven                 Systems                                                M&M Corporation        Robert Bosch
                                          Scala Consultants                     Data Analys Products
                                                                                        CSI
                                                                          LMS
Mixed innovatieve                                                                       Affilips
                                           South Lancs
bedrijven                                    Belgium

                                                                                                                 M.Hinoul
Feed-food-health
Kenniscentra                                                     GC Europe
                                                                               Interbrew Belgium
                                               Citrique Belg

                                                         Proefbedrijf voor witloof
Centers of                        Remy Industr
                                              Bodemkundige dienst België
excellence                                         SES Europe                     Engelhard Belgium         GE Betz

                         Sensient Centrum Toegep. Biol.
                                                             K.U.Leuven/VIB                    ICI-Europe
                          Flavors                                                                                    Pure
                                                   Center of Microbiol & Plant Gen.
                                                        Lab Molecular Cell Biology              Toxicon Europe
                                                                                                                   Global
                                     B.R.I.S.K.
                                                                                                                    Water
                                                                     KULeuven                                       Techn
                     Cargill
                                  Lochow-Petkus                                                    Hercules Europe
                    Frisk Intll      Belgium
                                                                    K.U.Leuven
                                                                                                       3E
                                                                 6 centers of excell.                            Omni Scala
                     Aveve               Better3Fruit
Pure innovatieve
                           Sodiaal                Quomak
bedrijven                  Benelux                                              Intern. Aquatreat Belgium   B.E.S.T.
                                                  Orafti Group
                               Tiense Suiker
                                                                   Kon. Belg. Inst. tot
Mixed innovatieve                                                  Verbetering vd Biet
                                                                                          Barco Elbicon
                                                  SST Food
bedrijven                                         Machinery

                                                                                                                      M.Hinoul
Life Sciences Cluster Leuven




                               M.Hinoul
Science parks, business centres &
                  incubators

•   Science Park Arenberg
•   Science Park Haasrode
•   Science Park Termunck
•   Science Park Waterschei - Genk
•   Science Park Tienen
•   Ubicenter
•   Campus Remy
•   Business Centre Leuven




                                           M.Hinoul
The Leuven
Science and Research Parks




                             M.Hinoul
HAASRODE RESEARCH
                              PARK
                            A full house – 5 000 jobs




                    
                
                   
           




                    

                       



                                                    M.Hinoul

          
          



           
              




                   M.Hinoul
Arenberg Science Park




                        M.Hinoul
Arenberg Science park-planning 2018
                                          Cluster D
                                         Bio 1 (full), 2
                                         (nearly), 3 (
                                            2013)
                                                               3

                                                  1        2
 Cluster B- ICT
25.000 m2 nearly                   D
   completed                   C
                           B
                   A
                       E
Cluster A- ICT
  35.000 m2
Van Roey-2015




                                      Cluster C
                                   Bio + Strip -2017
                                                               M.Hinoul
Masterplan Leuven Bio-Incubators
The Golden Leuven Bio Triangle




                                   M.Hinoul
Bio-Incubator I - Leuven




                                                            M.Hinoul
 Bio-incubator Leuven – Gaston Geenslaan 1, 3001 Heverlee
The Leuven Life Sciences Cluster




                                   M.Hinoul
Hospital
Gasthuisberg KU Leuven

                         Academic




                                 M.Hinoul
Tienen – Bio Generator to be
    opened in may 2013




                               M.Hinoul
Imec in Leuven




                 M.Hinoul
Multilevel interaction



                  KU LEUVEN



                    LRD
FINANCIAL                      Science
 WORLD      GFF                 parks
                                         REGION


                  Leuven.Inc


                  Economy


                                                  M.Hinoul
Cluster policy Leuven

                 2011 (est.)

     N° of      380 (130 spin
   companies        offs)


    Turn-over      8 bi €


      Jobs         16.000


                                M.Hinoul
The Value Chain*




                                                                                    nt ers
                                 Qual




                                                                               e ce
                                      ity o
                                                                                                                                 Knowledge Centers



                                                                          ledg
                                           f Lif e

         Go                                                                                                          rs          Entrepreneurs & Role Models

                                                                      Know
            ve                                                                                                  eu
               rn                                                                                             en
                 me
                   nt                                                                                    pr                      Money
                                                                                                    n tre
                                                                                                E                                Capital Markets
                                                                                                                                 Infrastructure
Ne tworks                                                                                                      Role Models       Cluster Policy
                                                                                                                                 Presence of International
                                                                                                                                  Companies
                                                                                                                                 Networks
                   es
                Ci                                                                                             Mone
          o na
              l                                                                                                    y             Government
      at i
   ern                                                                                                                           Quality of Life
Int
                                                                                             Ca
                                                                                                p
                              ic y




                                                     Infrastructure




                                                                                               it a
                         ol




                                                                                                   lM
                          P




                                                                                                     ar
                       er




                                                                                                       ke
                   ust




                                                                                                          ts
                Cl




                                                                                                                 * Gibbons – Saxenian - Hinoul         M.Hinoul
Success factors

• A critical mass of high quality research
• Multidisciplinary team & high value support
• Clear incentives to encourage researchers and
  research groups
• Favourable entrepreneurial climate in a university
  context
• Legal context in Flanders
• Instruments and networks that further professionalise
  technology transfer support




                                                      M.Hinoul
Quality of Life




                  M.Hinoul
M.Hinoul
A Top Technology Region




                          M.Hinoul
A Region with the right ingredients


                          Knowledge Centers
                          Entrepreneurs & Role Models
                          Money
                          Capital Markets
                          Infrastructure
                          Cluster Policy
                          Presence of International
                           Companies
                          Networks
                          Government
                          Quality of Life




                                                M.Hinoul
Knowledge Centres




                    M.Hinoul
Much more than the 3 % Lisbon target




                                  M.Hinoul
Cluster Policy




                 M.Hinoul
Cluster formation
 of World Scale

                    M.Hinoul
HIGH TECH SYSTEMS & MATERIALEN
                       Specialisatie en pieken: Selectie en typologie belangrijkste actoren
                                                                                  Nederlandse          DSP Valley
                                                                                  Vereniging                                 Sirris
                                                                                  voor Precisie-
                                                            Vereniging            technologie
                       TTR Nederland                        van de
                                                                                                                                         Walonie
                                                                                                                                         Espace                       TTR België
                                                            Nederlandse                            DAF            nv Graco
                                                            Chemische
                                                            Industrie
                                                                             Siemens VDO                                        Vista nv                    FMTC
                                                                                                                                                            (mechatronica)
  Kenniscentra en
                                                                                                Philips                                  Alro Holdings
  centers of excellence                    Chemelot
                                                                                                              Ford Werke
                                                           Bosch
                                                                                      Bosch Hydraulic
                                                           Packaging
                                                                                                                Borealis Polymers                     LAG
                                                                          Akzo Nobel                                                                  Trailers            FLAMAC
                                    Netherlands                                                                                 Epiq                                      (materialen
                                    Aerospace                                                   Campus        KUL                                                         onderzoek)
                                                                             Nedcar             Geleen
  Pure innovatieve                  Group (NAG)
                                                                                                                     Imec             DOW Belgium
                                                   Vanderlande                                               KUleuven                                       Spaas
  bedrijven                          ATC                           DSM                             Philips    UImec
                                                                                                                Hasselt                                     Kaarsen
                                     Eindhoven     Industries
                                                                                       Campus                                                                                 Agoria
                                                                         ASML          Eindhoven                 U Luik
                                                                                                          U Hasselt
                                                                                                                                      Tessenderlo
                                    Nederlandse                                                  Fraunhofer Institut Luik
                                                                                                                 U                    chemie
                                                                       Océ                 Forschungszentrum Jülich                                      Heraeus
                                    vereniging
                                                     Stork food                            RWTH                                                          Electro-Nite
                                    voor rubber                                                     Hochschule
                                                     systems en                            Aachen Niederrhein                                            International
                                    en                                         Continental
                                                     printing                                                      Schumag AG
                                    kunststoffen
 Mixed innovatieve                                                                                                                                                       Flanders
                                                                        Siempelkamp           Philips (licht)/ Philips   Oerlikon Textile                                Drive
 bedrijven                                                 Cerobear
                                                                                              Onderzoeksinstituut
                                                                                Trützschler                   Scheidt & Bachmann               Pierberg
                                                                                          Prüfcentrum Siemens
                                              Verband der
                                                                      FEV                 transportation Systems                      Voith Paper
                                              Chemischen                                                                                                 Verband der
                                                                      Motorentechnik
                                              industrie (VCI)                                                                                            Elektrotechnik
                                                                                                             3M                                          (VDE)
                                                                                                                         AUNDE
                                                           Cluster Chemie/
                                                           Kunststoffe                     Munters Euroform
 Netwerken*                                                Mitteldeutschland
                                                                                                                                           CAR e.V.

                                                                          INTRA e.V.
                                                                                               Verbundinitiative Automobil                                    TTR Duitsland
                                                                                               Nordrhein-Westfalen (VIA NRW)
* Internationaal netwerk: Automotive.net

                                                                                                                                                                                        M.Hinoul
LIFE SCIENCES & MEDISCHE TECHNOLOGIE
                       Specialisatie en pieken: Selectie en typologie belangrijkste actoren

                                  TTR Nederland                                         LifeTec Network
                                                                                                                     Flanders’Bio
                                                                                                                                                           TTR België
                                                                                             Technomed            Helvoet Pharma
                                                          Life                                                                                    Life Science
                                                          Sciences                                                                                Platform
                                                          Limburg                Supra Polix                                   Tosoh
  Kenniscentra en                                         (LIOF)                                                               Bioscience
  centers of excellence                                                                                                                  Kingfisher
                                                                     Occam                 Philips Medical        Thromb-X               Healthcare
                                                                                           Systems
                                                                                                                   OncoMethylome
                                                            Pamgene               Medtronic                                                     Spronken
                                                                                                                  KUL         Neurgenetics      Orthopedie         BioLiege
                                          Healthcare &                       Pie Medical       AZ Maastricht            VIB
                                          Technology
  Pure innovatieve                        Knowledge                                                              BIOMED             Medinvest
                                                                                                                 KUleuven                          Ortec
  bedrijven                               Network          Blue                                U Maastricht          U Hasselt        Silicos
                                                           Medical                                                 Imec
                                                                         Akzo Nobel/        TU                    UZ Leuven
                                                                         Organon            Eindhoven              U Hasselt                       Centocor
                                                                                                                           IMEC
                                                                                                             Kath. FH U Luik           Pharma
                                                                                                                                                                     BioWin
                                                                                                         NRW                           Neuro
                                                                                                 RWTH Forschungszentrum                Boost       Terumo
                                            Human                              DSM
                                                           Notox                                 Aachen Jülich (IME)                               Europe
                                            Health
                                                                                                        UK Aachen
                                                                                                                           Abiomed
 Mixed innovatieve                                                                     Dräger                            Europe Gmbh
 bedrijven                                                             Activ Care
                                                                                       Medical
                                                                    transcon Gmbh                       Grünenthal
                                                                                                                                                             Spectaris
                                                     Bioriver Life                                                                    DASGIP AG
                                                     Science Cluster           Pharma Aldenhoven
                                                                                                                   Trommsdorff                  LifeTec Aachen-
                                                                                                                                                Jülich
                                                                   Tri-nationale
                                                                   MaasRijn triangle
                                                                   cluster                                                           MetNet NRW
 Netwerken*                                                                      Bundesverband der
                                                                                 Pharmazeutischen               Aachener                               TTR Duitsland
                                                                                 Industrie e.v. (BPI)           Kompetenzzentrum
                                                                                                                Medizintechnik AKM
*Alma-grid: LSMT samenwerkingsproject Luik, Hasselt, Maastricht, Aken
                                                                                                                                                                              M.Hinoul
*Heartbeat: INTERREG III initiatief MaasRijn triangle                                                                                                                                    64
FOOD & NUTRITION
              Specialisatie en pieken: Selectie en typologie belangrijkste actoren
                                                                           Regio Uden-Veghel

                                                       Foodregio
                                                                                                                      Flanders’ FOOD
              TTR Nederland                            Helmond e.o./
                                                       Greenport Venlo
                                                                                                                                                            TTR België
                                                                                                     Interbrew
                                                                            Flora Holland
                                                                                                             Farm Frites Belgium
Kenniscentra en                  Foodvalley regio                                                                                                 FEVIA
                                                           Veiling ZON
centers of excellence            Wageningen
                                                                                         Nutreco       SES                  Tropicana Looza
                                                                                                       Europe
                                                     Rendac                Wessanen
                                                                                                                                   Lambrechts nv
                                                                                                            Better3Fruit
                                                                                Newtrition                                                                Choprabisco
                         Food &                                                                                    Orafti Group
                                                               Masters Food                                                              Veiling
                         Nutrition                                                  U Maastricht
Pure innovatieve         Topinstituut
                                             Nedalco                                                    KUL
                                                                                                                           Hercules      Haspengouw
                                                                                                       KUleuven            Europe
bedrijven                                                                       HAS Den Bosch
                                            DMV               Unilever                                    Imec
                                                                                                     Proefcentrum
                                                                                                                                              Tiense
                                            Campina                            U Wageningen          Fruitteelt vzw          Scana
                                                                                                      U Hasselt                               Suiker
                                                                                                                             Noliko
                                                                Numico
                        Food                                                    Fontys         HochSchule U Luik                                              Provinciaal
                        Concortium                                                             Niederrhein                    IncoPack                        Overleg
                                                              Heineken
                                                                                                                                            Citrique          Regio
                                             Sovion                                          Frauenhofer
                                                                                                                                            Belge             Tienen
                           Food                                                              Gesellschaft
                                                                          Zentis                                   KronenBrot
                           Connection
Mixed innovatieve          Point                                                                                   KG
bedrijven                                                                       Chocoladefabriken Lindt
                                                                                                                                  Leuchtenberg
                                                      Nestle                                         Carl kühne FG
                                                      Deutschland                          Cargill
                                                                                                                           Landgard              Deutsche
                                        Food
                                                                                                                                                 Landwirtschaft
                                        Processing
                                                                         Zuckerfabrik Jülich                                                     Gesellschaft
                                        Initiative
                                                                                                                                                 (DLG)
                                                                                         Walter Rau Neusser Öland

Netwerken                                             Deutsches Institut für
                                                                                                                                Agrobusiness
                                                      Lebensmitteltechnik
                                                                                     Bundesvereinigung               Foodcity
                                                                                     der Deutschen                                         TTR Duitsland
                                                                                     Ernährungsindustrie


                                                                                                                                                                            M.Hinoul
High Tech
                        Systems and       Food/Nutrition           Life Sciences         Total
                         Materials
Netherlands              127 000               92 000                  19 000          238 000
Belgium                   58 000               39 000                    7000          104 000
Germany                  104 000               58 000                  16 000          178 000

Total                    289 000              189 000                  42 000          520 000

Total Added Value
                            20                      9                      3             32
(billion €uro)
Total Added Value per
employee                 69 000 €             48 000 €                71 000 €         61 000 €

                             Source : Policy Research, Hochschule Niederrhein, Etil.       M.Hinoul
EEN STERKE ECONOMISCHE GROEI VOOR DE ELAt REGIO


                                     BNP           BNP/Actief
6 mi inwoners      2,9 mi actief    157 Bi €        54.000
                520.000 HTW (1/5)   32 Bi € 6,4%    61.000 7,5%
6 mi inwoners      2,9 mi actief    167 Bi €        58.000
                700.000 HTW (1/4)   42 Bi €         61.000




                                                                M.Hinoul
HIGH TECH SYSTEMS & MATERIALEN
                       Specialisatie en pieken: Selectie en typologie belangrijkste actoren
                                                                                  Nederlandse          DSP Valley
                                                                                  Vereniging                                 Sirris
                                                                                  voor Precisie-
                                                            Vereniging            technologie
                       TTR Nederland                        van de
                                                                                                                                         Walonie
                                                                                                                                         Espace                       TTR België
                                                            Nederlandse                            DAF            nv Graco
                                                            Chemische
                                                            Industrie
                                                                             Siemens VDO                                        Vista nv                    FMTC
                                                                                                                                                            (mechatronica)
  Kenniscentra en
                                                                                                Philips                                  Alro Holdings
  centers of excellence                    Chemelot
                                                                                                              Ford Werke
                                                           Bosch
                                                                                      Bosch Hydraulic
                                                           Packaging
                                                                                                                Borealis Polymers                     LAG
                                                                          Akzo Nobel                                                                  Trailers            FLAMAC
                                    Netherlands                                                                                 Epiq                                      (materialen
                                    Aerospace                                                   Campus        KUL                                                         onderzoek)
                                                                             Nedcar             Geleen
  Pure innovatieve                  Group (NAG)
                                                                                                                     Imec             DOW Belgium
                                                   Vanderlande                                               KUleuven                                       Spaas
  bedrijven                          ATC                           DSM                             Philips    UImec
                                                                                                                Hasselt                                     Kaarsen
                                     Eindhoven     Industries
                                                                                       Campus                                                                                 Agoria
                                                                         ASML          Eindhoven                 U Luik
                                                                                                          U Hasselt
                                                                                                                                      Tessenderlo
                                    Nederlandse                                                  Fraunhofer Institut Luik
                                                                                                                 U                    chemie
                                                                       Océ                 Forschungszentrum Jülich                                      Heraeus
                                    vereniging
                                                     Stork food                            RWTH                                                          Electro-Nite
                                    voor rubber                                                     Hochschule
                                                     systems en                            Aachen Niederrhein                                            International
                                    en                                         Continental
                                                     printing                                                      Schumag AG
                                    kunststoffen
 Mixed innovatieve                                                                                                                                                       Flanders
                                                                        Siempelkamp           Philips (licht)/ Philips   Oerlikon Textile                                Drive
 bedrijven                                                 Cerobear
                                                                                              Onderzoeksinstituut
                                                                                Trützschler                   Scheidt & Bachmann               Pierberg
                                                                                          Prüfcentrum Siemens
                                              Verband der
                                                                      FEV                 transportation Systems                      Voith Paper
                                              Chemischen                                                                                                 Verband der
                                                                      Motorentechnik
                                              industrie (VCI)                                                                                            Elektrotechnik
                                                                                                             3M                                          (VDE)
                                                                                                                         AUNDE
                                                           Cluster Chemie/
                                                           Kunststoffe                     Munters Euroform
 Netwerken*                                                Mitteldeutschland
                                                                                                                                           CAR e.V.

                                                                          INTRA e.V.
                                                                                               Verbundinitiative Automobil                                    TTR Duitsland
                                                                                               Nordrhein-Westfalen (VIA NRW)
* Internationaal netwerk: Automotive.net
                                                                                                                                                                                        M.Hinoul
Enabling The Digital Age(nda)

                        Electronics Industry
                          ~2000 B$/year


                       Chipmaking Industry
                          ~300 B$/year


                  Lithographic Equipment Industry
                            ~10 B$/year


                  DUV/EUV Light Source Industry
                          ~1B$/year
                                           M.Hinoul
Aachen/Alsdorf




                    System                              Suppliers




Process (Masks, Resist,..)                     Lightsource




                      Taking light to 70
                                      new dimensions…
                                                                    M.Hinoul
The technological challenge:
  the winner takes it all…?




                               M.Hinoul
M.Hinoul
confidential   72
M.Hinoul
confidential
Printing 1000.000.000 transistors/second
towards 13,5nm wavelength EUV-sources




                              Source ASML
                                            M.Hinoul
Source Integrated with ASML NXE:3100 @ imec




                                         M.Hinoul
How Partnerships Can Help
                                  Closing the loop on system performance
  The Netherlands
                                  within the Euregio

                                  Having access to all major IC companies
                                  through Imec’s litho partners
                    Germany
                                  Creating an ecosystem of
                                  specialized module suppliers

                                  Becoming a showcase of hightech
                     Fraunhofer   for the rest of the world
        Belgium
                           ILT




                                                                  M.Hinoul
How Partnerships Can Help
                                  Closing the loop on system performance
  The Netherlands
                                  within the Euregio

                                  Having access to all major IC companies
                                  through Imec’s litho partners
                    Germany
                                  Creating an ecosystem of
                                  specialized module suppliers

                                  Becoming a showcase of hightech
                     Fraunhofer   for the rest of the world
        Belgium
                           ILT




                                                                  M.Hinoul
Lam
      RESEARCH
                                       STMicroelectronics




Imec and the World’s Largest Industry Commitment
    to Semiconductor Research in Partnership     M.Hinoul
Infrastructures




                  M.Hinoul
The Eindhoven HighTech Campus




                            M.Hinoul
The DSM – Chemelot High Tech
          Campus




                               M.Hinoul
RWTH Aachen Campus

•15 Clusters
•10 000 new jobs
•2 Billion € investment




                                    M.Hinoul
Bio Incubator(s) Maastricht




                              M.Hinoul
Thor Research Park Waterschei




                                M.Hinoul
BioVille Incubator Diepenbeek




                                M.Hinoul
Sart Tilman Liège




                    M.Hinoul
The Leuven Research Parks




Termunck

                       Haasrode
            Arenberg




                                  M.Hinoul
Life Science Cluster
Kenniscentra                                                  E.S.R.I.
                                                            Deckers Div      Biotest Seralco
                                                                                Benelux
                                    Dermat                   Thrombogenics
Centers of                                                                                             Terumo
                                                        Tigenix                    ReMynd
excellence                                                IDT(RNA-TEC)
                                                                                                       Europe
                                                                       Dakocytomation
                                      BioTie Therapies Corp.
                         Norgine                                  Univ hospitals
                                                                   K.U.Leuven               Cochlear
                                   Algonomics                     Rega Institute
                                                                      CEHA                      M-Elect
                                PatientWeb         Lab of Exp. Genetics & Transgenese                            Autocyte
                   Medvision                                                                           M4S        Europe
                    Benelux      Materialise                      K.U.Leuven                    Neurogenetics
                                                                    L-MTC
                                   QMedit
                                                                                              @Medical Techn.
                                    MXS                              VIB
                      IVIA
                                                                   VIGOUR
                                    Custom8                                             Onco
Puur innovatieve                                                                                               Conti BPC
                                                                                        Methylome
bedrijven                                      Fugeia
                                                                                       Regenesys
                                                            Diatos
                                               Medicim                  New Standard Eng.
                               Malaise&co
                                                                  Formac                               Ortec
                                                   CMPG
Gemengd innovatieve                                           Pharmaceuticals

bedrijven                                   Centocor
                                                                       VWR International

                                                                                                                  M.Hinoul
LIFE SCIENCES & MEDISCHE TECHNOLOGIE
                       Specialisatie en pieken: Selectie en typologie belangrijkste actoren

                                  TTR Nederland                                         LifeTec Network
                                                                                                                     Flanders’Bio
                                                                                                                                                           TTR België
                                                                                             Technomed            Helvoet Pharma
                                                          Life                                                                                    Life Science
                                                          Sciences                                                                                Platform
                                                          Limburg                Supra Polix                                   Tosoh
  Kenniscentra en                                         (LIOF)                                                               Bioscience
  centers of excellence                                                                                                                  Kingfisher
                                                                     Occam                 Philips Medical        Thromb-X               Healthcare
                                                                                           Systems
                                                                                                                   OncoMethylome
                                                            Pamgene               Medtronic                                                     Spronken
                                                                                                                  KUL         Neurgenetics      Orthopedie         BioLiege
                                          Healthcare &                       Pie Medical       AZ Maastricht            VIB
                                          Technology
  Pure innovatieve                        Knowledge                                                              BIOMED             Medinvest
                                                                                                                 KUleuven                          Ortec
  bedrijven                               Network          Blue                                U Maastricht          U Hasselt        Silicos
                                                           Medical                                                 Imec
                                                                         Akzo Nobel/        TU                    UZ Leuven
                                                                         Organon            Eindhoven              U Hasselt                       Centocor
                                                                                                                           IMEC
                                                                                                             Kath. FH U Luik           Pharma
                                                                                                                                                                     BioWin
                                                                                                         NRW                           Neuro
                                                                                                 RWTH Forschungszentrum                Boost       Terumo
                                            Human                              DSM
                                                           Notox                                 Aachen Jülich (IME)                               Europe
                                            Health
                                                                                                        UK Aachen
                                                                                                                           Abiomed
 Mixed innovatieve                                                                     Dräger                            Europe Gmbh
 bedrijven                                                             Activ Care
                                                                                       Medical
                                                                    transcon Gmbh                       Grünenthal
                                                                                                                                                             Spectaris
                                                     Bioriver Life                                                                    DASGIP AG
                                                     Science Cluster           Pharma Aldenhoven
                                                                                                                   Trommsdorff                  LifeTec Aachen-
                                                                                                                                                Jülich
                                                                   Tri-nationale
                                                                   MaasRijn triangle
                                                                   cluster                                                           MetNet NRW
 Netwerken*                                                                      Bundesverband der
                                                                                 Pharmazeutischen               Aachener                               TTR Duitsland
                                                                                 Industrie e.v. (BPI)           Kompetenzzentrum
                                                                                                                Medizintechnik AKM
*Alma-grid: LSMT samenwerkingsproject Luik, Hasselt, Maastricht, Aken
                                                                                                                                                                              M.Hinoul
*Heartbeat: INTERREG III initiatief MaasRijn triangle
Networks




           M.Hinoul
Bio-incubators and alliances

                        Novartis
Merck Serono                             Roche


  P&G                                            Roche

                     Bio-incubators
 Pfizer 212                                      Centocor


               J&J                 GSK

                                                         M.Hinoul
M.Hinoul
Health Axis Europe
M.O.U. Signed in Leuven




                                                  © K.U.Leuven - Rob Stevens
                     Leuven, June   8th,   2011

                                                                       M.Hinoul
Structure
                         Leuven
                     Sub-Committee
                          (10)
                                         Health Axis Europe
                                                 Committee
                                                 (10+10+10)
                     Executive Board
                         (3+3+3)

       Cambridge                         Heidelberg
     Sub-Committee                     Sub-Committee
          (10)                              (10)



                                                       M.Hinoul
Leuven Sub-Committee
  Members

                 Prof. Dr. Minne Casteels*                                     Prof. Dr. Koenraad Debackere*
                     Vice rector of the Biomedical Sciences                    Managing Director, KU Leuven
                                          Group, KU Leuven


      Prof. Dr. Frank Luyten                                                                   Prof. Dr. Piet Stinissen
    Head of the Division of Rheumatology,                                                      Dean of the Faculty of Medicine and
              University Hospitals Leuven                                                      Life Sciences, Hasselt University



        M.B.A Koen De                                             Leuven                               M.B.A. Johan Van
                Witte                                         Sub-Committee                            Helleputte*
     Managing Director, reMYND                                                                         Senior Vice President Strategic
                                                                                                       Development Unit, imec


         Dr. Patrik De Haes                                                                    Prof. Dr Mark Waer
               Chief Executive Officer,                                                        Rector, KU Leuven
                      ThromboGenics



                                    Dr. Bart Haex                             Dr. Patrick Chaltin
                                   Strategic Development                      Managing Director, CD3




* Member of Health Axis Europe Executive Board                                                                                       M.Hinoul
M.Hinoul
M.Hinoul
M.Hinoul
M.Hinoul
M.Hinoul
M.Hinoul
M.Hinoul
Success factors

   Cutting-edge science and technology
   Tradition in technology transfer
   An innovative business climate with high-tech companies and state-
    of-the-art incubators & science parks
   Seed capital, venture capital, growth capital , access to capital
    markets
   Talent
   Networking opportunities
   International affiliations




                                                                 M.Hinoul
Contact


KU Leuven Research & Development (LRD)

Waaistraat, 6
3000 Leuven, Belgium
+32 16 32 65 00
lrd@kuleuven.be
lrd.kuleuven.be
Leuven, a region for innovation & high-tech entrepreneurship - Martin Hinoul

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Leuven, a region for innovation & high-tech entrepreneurship - Martin Hinoul

  • 1. Flanders as a creative innovative region Leuven, a region for innovation & high-tech entrepreneurship Dr Martin Hinoul Business Development Manager KU Leuven Leuven , December 12, 2012
  • 3. From a Globe to a Flat World Source:Awex For thousands of years we were living on a globe where innovation was a very slow process M.Hinoul
  • 4. SIR* World Report 2012 INDICATORS • Output • International Collaboration • Normalized Impact • High Quality Publications • Specialization Index (Gini index) • Excellence Rate • 3290 Research Institutions (strong criteria) • more than 80% of the world scientific output (2006-2010) (Global Ranking KU Leuven 68 – (universities 32) - European Ranking KU Leuven 5) *Scimago Institutions Rankings M.Hinoul
  • 5. World’s GDP and R&D Budgets ! 1,74 tr $ 16,5 tr $ 18 tr $ 6,4 tr $ 5 tr $ 2,8% R&D 2% R&D 1,5 tr $ 2 tr $ Source : The World Bank-Reshaping Economic Geography, Hinoul M.Hinoul
  • 6. The Economist Intelligence Unit Limited (Dec. 2011)  There are few economic policies as popular as research parks, incubators and clusters –very hot today.  It is hard today to find a country, region, or even a city that is not trying to develop a network of competitive firms (clusters)  The “political appeal” is therefore obvious, particularly now that the world’s economic crisis has put a spotlight on “innovation” to diversify economies and create jobs  However the difficulty lies in turning these “science parks”, incubators or “hi-tech”corridors into success stories. Not so simple. M.Hinoul
  • 7. Globally there are more than 1400 cluster initiatives  Hollywood  Bordeaux  New York & London financial services  Silicon Valley  San Diego – Biotech Triangle  Cambridge Phenomenon M.Hinoul
  • 8. World’s Knowledge 2012 and formation of knowledge economy regions M.Hinoul
  • 9. Indeed formation of Knowledge Economy Regions M.Hinoul
  • 10. Globally there are more than 50 well developed knowledge economy regions Source : Vacature – M.Hinoul M.Hinoul
  • 11. Source : Harvard Business Review July-August2012 – p.26 M.Hinoul
  • 12. Leuven, a region for innovation & high-tech entrepreneurship M.Hinoul
  • 13. The Leuven Region Close to Brussels Leuven Region: 95.000 habitants Airport Leuven Brussels M.Hinoul
  • 14. An old young city M.Hinoul
  • 15. Leuven, a region for innovation & high-tech entrepreneurship  Leuven provides the key ingredients for innovation and high-tech entrepreneurship:  Cutting-edge science & technologies  A long tradition of technology transfer (40 years)  An innovative business climate with many high-tech companies and state-of-the- art incubators & science parks  Investment capital  People & networking opportunities  International affiliations  Collaboration with Mayor of Leuven M.Hinoul
  • 16. Knowledge institutes  K.U.Leuven Association  Leuven University Hospitals  imec  VIB departments  Combined R&D budget of 664 million € (KU Leuven and Imec)  Employ about 19,500 people (6,400 researchers)  Huge inflow of knowledge and innovative ideas  Attractive location for high-tech companies  High-tech ecosystem M.Hinoul
  • 17. Facts & Figures 1. Students 3. Research • 40.257 students : 21. 927 f • Researchers (fte) 18. 204 m • Professors 1018 (12% international) • 45% Bachelor • Postdocs 1052 (36% international) 31% Master • Doctorandi 4381 (38% international) 5% Master-after-master • R&D Budget 11% Doctor program 1% Teachers education 364 million Euro (2011) 7% others • 5199 publications (in 2010) • 625 doctors (in 2010-2011) • 6. 248 International students : - 3.204 EU students • 98 spin-off companies (2011) - 3.017 others 2. Education 4.Personnel KU Leuven • Dutch language programs 18.635 people • 55 bachelor • 9.971 at the university • 132 master • 8.664 at the University Hospitals • 53 master-after-master - programs • International language : • 47 master • 31 master after master • 2 bachelor – programs in English M.Hinoul
  • 18. Students KU Leuven ( 2011 – 2012) Total 40.257 Law / Economy 8.741 21,7 % Sciences / Engineering 8.844 22,0 % Medical / Pharmacy 7.974 19,8 % Languages 4.572 11,4% Other 10.126 25,2% M.Hinoul
  • 19. University Leuven IMEC Knowledge Centers 664 mi€ R&D, 6400 Researchers 300 Technology Cies, 135 spin offs High Tech Industrie Life Sciences Nanotechnology Mechatronics Cleantech Clusters Technology Platforms Haasrode Arenberg Leuven Noord Genk THOR Tienen FFH Research Parks Networks M.Hinoul
  • 20. Leuven, specialising in four technology domains • Life sciences • Nanotechnology • Mechatronics & smart systems • Cleantech © imec M.Hinoul
  • 22. K.U.Leuven Research & Development received the 2008 IPTEC Tech Transfer Award Nominated: •K.U.Leuven R&D (Winner 2008) •Columbia University (USA) •Imperial Innovations (UK) •MIT (USA) •Wisconsin Alumni Research Foundation (USA) Received the award : •2006 : Stanford University (USA) •2007 : Tsinghua University (China) M.Hinoul © 2007 LRD
  • 23. What is LRD? • Founded in 1972 (40 years young this year) • Technology and knowledge transfer office of K.U.Leuven • Bridge between university, industry and society • Supports researchers • Offers technologies to industry • Large budgetary and HR autonomy • ‘Business unit’ M.Hinoul
  • 24. K.U.Leuven: Organisation • K.U.Leuven Education Policy Research Policy DOC: Research Coördination K.U.Leuven R&D: valorisation Professional Support Research Divisions Faculties Departments Research Projects M.Hinoul
  • 25. What do we do? • Research collaboration • Protection and exploitation of intellectual property • Spin-off creation & innovation • Support of regional development • Stimulation of entrepreneurship through network initiatives M.Hinoul
  • 26. Research collaboration • Oldest activity of LRD • Performing research & services for companies or governments • What do we do? – Creating awareness and transferring knowledge – Providing advice – Negotiating contracts – Following up on contracts – Managing research files financially – Offering administrative support – Preparing legal documents M.Hinoul
  • 27. Contract Research € 160.000 thousands 160.000 € 140.000 144.802 € 120.000 126.807 121.653 € 100.000 97.844 87.908 € 80.000 70.193 € 60.000 54.332 € 40.000 € 20.000 €0 2004 2005 2006 2007 2008 2009 2010 2011 M.Hinoul
  • 28. Intellectual property • What do we do? – Creating awareness and transferring knowledge – Assessing the feasibility, patentability and market potential of an invention – Determining a protection strategy – Drafting and filing a patent application – Following up on patent procedures and costs – Negotiating and drafting NDA’s, MTA’s and license agreements – Finding industrial partners M.Hinoul
  • 29. Spin-offs & innovation • What do we do? – Developing business plans – Validating business models and the market – Offering legal support – Putting together a competent team – Finding investors – Finding infrastructure – Growth management – Promoting valorisation and entrepreneurship – Stimulating regional development, networks and clusters M.Hinoul
  • 30. Spin-offs & innovation • Gemma Frisius Fund K.U.Leuven (GFF) – Seed capital for spin-off companies – GFF founded in 1997 & GFF II in 2002 • At the end of 2009 GFF and GFF II merged into one single fund – Partners: • K.U.Leuven (20% of capital) • Two banks: KBC Private Equity (40%) en Fortis Private Equity (40%) – Combination between: • Research and technology transfer expertise (university) • Financial expertise (financial partners) – Not restricted to a specific technology domain – 24.9 million euro capital (22.9 million invested, 28 companies) M.Hinoul
  • 31. K.U.Leuven Spin offs 100 90 80 70 Gemma Frisius-Seed Capital 60 2x 12,5 m€ 50 40 30 20 10 0 1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012 M.Hinoul
  • 32. Spillovers and multipliers • Multipliers --- spin-offs, 2006 - 2010: – K.U.Leuven direct investments: 4,7 M€ – (Gemma Frisius Fund investments: 12 M€) – Other third party investments: 476 M€ • Patent portfolios: – K.U.Leuven R&D, 454 active patent families of which 90% economically exploited – Multiplier effects of patent portfolios of spin-off companies  sectoral multipliers of 3-to-4 M.Hinoul
  • 33. Creating leverage M.Hinoul
  • 34. Capital Markets  Other capital markets  IT- Partners, Fortis Private Equity, KBC Investco  Stockmarket  Ubizen  ICOS  Option  Telindus  Quest for Growth  OMS  Thrombogenics (1,4Bi Euro)  Metris  Tigenix  ….. M.Hinoul
  • 35. Micro-elektronica - nanotechnologie Kenniscentra Eyetronics Telindus B.E.S.T. Newfrom Tyco Electronics Centers of A.C.S. Belgium Resonext Option International Cypress Semi excellence Eonic Systems ARM Luciad FillFactory Assurcard Vivactiss K.U.Leuven STM ICOS Vision Lab Photochemistry & Spectroscopy Tomoton Systems Lab of Solid-state Physics & Magnetism Agilent Techn. JSR Electronics J.W.Lemmens Vector International KULeuven Micro Matic IPCOS IMEC Photovoltec Philips ITCL Xenics IMEC Septentrio Sub-45nm research facility Delcomp Oligosense Nanotechnology Platform Pure innovatieve Design platform ASM Belgium Krypton Epiq Sensor Nite bedrijven Target Compiler Techn. Data4S Soltech AnSem Easics CoWare Mixed innovatieve Mind Linux LMS bedrijven Solutions M.Hinoul
  • 36. Mechatronica Kenniscentra Stas Alnaco Ora Machines B.E.S.T. Optidrive Centers of ACE Electronics WTCM Air Beraing Prec. Techn. excellence Barco Aarschot Electrical & Mech. Design Donaldson DV Consulting IPCOS Partec Eng Materialise K.U.Leuven Krypton Dept. Mechanics Dynamotor Researh groups Decoster Luyten Automation Metris Somatech KULeuven SST Food Mach Atos Engineering PEC EME K.U.Leuven Camco Entecom Systems Dept of Metall. & Mater. Eng Tecmate Techn Lab Agric Mach & Proc Pure innovatieve Intl. Flexlink D2S International bedrijven Systems M&M Corporation Robert Bosch Scala Consultants Data Analys Products CSI LMS Mixed innovatieve Affilips South Lancs bedrijven Belgium M.Hinoul
  • 37. Feed-food-health Kenniscentra GC Europe Interbrew Belgium Citrique Belg Proefbedrijf voor witloof Centers of Remy Industr Bodemkundige dienst België excellence SES Europe Engelhard Belgium GE Betz Sensient Centrum Toegep. Biol. K.U.Leuven/VIB ICI-Europe Flavors Pure Center of Microbiol & Plant Gen. Lab Molecular Cell Biology Toxicon Europe Global B.R.I.S.K. Water KULeuven Techn Cargill Lochow-Petkus Hercules Europe Frisk Intll Belgium K.U.Leuven 3E 6 centers of excell. Omni Scala Aveve Better3Fruit Pure innovatieve Sodiaal Quomak bedrijven Benelux Intern. Aquatreat Belgium B.E.S.T. Orafti Group Tiense Suiker Kon. Belg. Inst. tot Mixed innovatieve Verbetering vd Biet Barco Elbicon SST Food bedrijven Machinery M.Hinoul
  • 38. Life Sciences Cluster Leuven M.Hinoul
  • 39. Science parks, business centres & incubators • Science Park Arenberg • Science Park Haasrode • Science Park Termunck • Science Park Waterschei - Genk • Science Park Tienen • Ubicenter • Campus Remy • Business Centre Leuven M.Hinoul
  • 40. The Leuven Science and Research Parks M.Hinoul
  • 41. HAASRODE RESEARCH PARK A full house – 5 000 jobs          M.Hinoul
  • 42.         M.Hinoul
  • 44. Arenberg Science park-planning 2018 Cluster D Bio 1 (full), 2 (nearly), 3 ( 2013) 3 1 2 Cluster B- ICT 25.000 m2 nearly D completed C B A E Cluster A- ICT 35.000 m2 Van Roey-2015 Cluster C Bio + Strip -2017 M.Hinoul
  • 45. Masterplan Leuven Bio-Incubators The Golden Leuven Bio Triangle M.Hinoul
  • 46. Bio-Incubator I - Leuven M.Hinoul Bio-incubator Leuven – Gaston Geenslaan 1, 3001 Heverlee
  • 47. The Leuven Life Sciences Cluster M.Hinoul
  • 48. Hospital Gasthuisberg KU Leuven Academic M.Hinoul
  • 49. Tienen – Bio Generator to be opened in may 2013 M.Hinoul
  • 50. Imec in Leuven M.Hinoul
  • 51. Multilevel interaction KU LEUVEN LRD FINANCIAL Science WORLD GFF parks REGION Leuven.Inc Economy M.Hinoul
  • 52. Cluster policy Leuven 2011 (est.) N° of 380 (130 spin companies offs) Turn-over 8 bi € Jobs 16.000 M.Hinoul
  • 53. The Value Chain* nt ers Qual e ce ity o  Knowledge Centers ledg f Lif e Go rs  Entrepreneurs & Role Models Know ve eu rn en me nt pr  Money n tre E  Capital Markets  Infrastructure Ne tworks Role Models  Cluster Policy  Presence of International Companies  Networks es Ci Mone o na l y  Government at i ern  Quality of Life Int Ca p ic y Infrastructure it a ol lM P ar er ke ust ts Cl * Gibbons – Saxenian - Hinoul M.Hinoul
  • 54. Success factors • A critical mass of high quality research • Multidisciplinary team & high value support • Clear incentives to encourage researchers and research groups • Favourable entrepreneurial climate in a university context • Legal context in Flanders • Instruments and networks that further professionalise technology transfer support M.Hinoul
  • 55. Quality of Life M.Hinoul
  • 57. A Top Technology Region M.Hinoul
  • 58. A Region with the right ingredients  Knowledge Centers  Entrepreneurs & Role Models  Money  Capital Markets  Infrastructure  Cluster Policy  Presence of International Companies  Networks  Government  Quality of Life M.Hinoul
  • 59. Knowledge Centres M.Hinoul
  • 60. Much more than the 3 % Lisbon target M.Hinoul
  • 61. Cluster Policy M.Hinoul
  • 62. Cluster formation of World Scale M.Hinoul
  • 63. HIGH TECH SYSTEMS & MATERIALEN Specialisatie en pieken: Selectie en typologie belangrijkste actoren Nederlandse DSP Valley Vereniging Sirris voor Precisie- Vereniging technologie TTR Nederland van de Walonie Espace TTR België Nederlandse DAF nv Graco Chemische Industrie Siemens VDO Vista nv FMTC (mechatronica) Kenniscentra en Philips Alro Holdings centers of excellence Chemelot Ford Werke Bosch Bosch Hydraulic Packaging Borealis Polymers LAG Akzo Nobel Trailers FLAMAC Netherlands Epiq (materialen Aerospace Campus KUL onderzoek) Nedcar Geleen Pure innovatieve Group (NAG) Imec DOW Belgium Vanderlande KUleuven Spaas bedrijven ATC DSM Philips UImec Hasselt Kaarsen Eindhoven Industries Campus Agoria ASML Eindhoven U Luik U Hasselt Tessenderlo Nederlandse Fraunhofer Institut Luik U chemie Océ Forschungszentrum Jülich Heraeus vereniging Stork food RWTH Electro-Nite voor rubber Hochschule systems en Aachen Niederrhein International en Continental printing Schumag AG kunststoffen Mixed innovatieve Flanders Siempelkamp Philips (licht)/ Philips Oerlikon Textile Drive bedrijven Cerobear Onderzoeksinstituut Trützschler Scheidt & Bachmann Pierberg Prüfcentrum Siemens Verband der FEV transportation Systems Voith Paper Chemischen Verband der Motorentechnik industrie (VCI) Elektrotechnik 3M (VDE) AUNDE Cluster Chemie/ Kunststoffe Munters Euroform Netwerken* Mitteldeutschland CAR e.V. INTRA e.V. Verbundinitiative Automobil TTR Duitsland Nordrhein-Westfalen (VIA NRW) * Internationaal netwerk: Automotive.net M.Hinoul
  • 64. LIFE SCIENCES & MEDISCHE TECHNOLOGIE Specialisatie en pieken: Selectie en typologie belangrijkste actoren TTR Nederland LifeTec Network Flanders’Bio TTR België Technomed Helvoet Pharma Life Life Science Sciences Platform Limburg Supra Polix Tosoh Kenniscentra en (LIOF) Bioscience centers of excellence Kingfisher Occam Philips Medical Thromb-X Healthcare Systems OncoMethylome Pamgene Medtronic Spronken KUL Neurgenetics Orthopedie BioLiege Healthcare & Pie Medical AZ Maastricht VIB Technology Pure innovatieve Knowledge BIOMED Medinvest KUleuven Ortec bedrijven Network Blue U Maastricht U Hasselt Silicos Medical Imec Akzo Nobel/ TU UZ Leuven Organon Eindhoven U Hasselt Centocor IMEC Kath. FH U Luik Pharma BioWin NRW Neuro RWTH Forschungszentrum Boost Terumo Human DSM Notox Aachen Jülich (IME) Europe Health UK Aachen Abiomed Mixed innovatieve Dräger Europe Gmbh bedrijven Activ Care Medical transcon Gmbh Grünenthal Spectaris Bioriver Life DASGIP AG Science Cluster Pharma Aldenhoven Trommsdorff LifeTec Aachen- Jülich Tri-nationale MaasRijn triangle cluster MetNet NRW Netwerken* Bundesverband der Pharmazeutischen Aachener TTR Duitsland Industrie e.v. (BPI) Kompetenzzentrum Medizintechnik AKM *Alma-grid: LSMT samenwerkingsproject Luik, Hasselt, Maastricht, Aken M.Hinoul *Heartbeat: INTERREG III initiatief MaasRijn triangle 64
  • 65. FOOD & NUTRITION Specialisatie en pieken: Selectie en typologie belangrijkste actoren Regio Uden-Veghel Foodregio Flanders’ FOOD TTR Nederland Helmond e.o./ Greenport Venlo TTR België Interbrew Flora Holland Farm Frites Belgium Kenniscentra en Foodvalley regio FEVIA Veiling ZON centers of excellence Wageningen Nutreco SES Tropicana Looza Europe Rendac Wessanen Lambrechts nv Better3Fruit Newtrition Choprabisco Food & Orafti Group Masters Food Veiling Nutrition U Maastricht Pure innovatieve Topinstituut Nedalco KUL Hercules Haspengouw KUleuven Europe bedrijven HAS Den Bosch DMV Unilever Imec Proefcentrum Tiense Campina U Wageningen Fruitteelt vzw Scana U Hasselt Suiker Noliko Numico Food Fontys HochSchule U Luik Provinciaal Concortium Niederrhein IncoPack Overleg Heineken Citrique Regio Sovion Frauenhofer Belge Tienen Food Gesellschaft Zentis KronenBrot Connection Mixed innovatieve Point KG bedrijven Chocoladefabriken Lindt Leuchtenberg Nestle Carl kühne FG Deutschland Cargill Landgard Deutsche Food Landwirtschaft Processing Zuckerfabrik Jülich Gesellschaft Initiative (DLG) Walter Rau Neusser Öland Netwerken Deutsches Institut für Agrobusiness Lebensmitteltechnik Bundesvereinigung Foodcity der Deutschen TTR Duitsland Ernährungsindustrie M.Hinoul
  • 66. High Tech Systems and Food/Nutrition Life Sciences Total Materials Netherlands 127 000 92 000 19 000 238 000 Belgium 58 000 39 000 7000 104 000 Germany 104 000 58 000 16 000 178 000 Total 289 000 189 000 42 000 520 000 Total Added Value 20 9 3 32 (billion €uro) Total Added Value per employee 69 000 € 48 000 € 71 000 € 61 000 € Source : Policy Research, Hochschule Niederrhein, Etil. M.Hinoul
  • 67. EEN STERKE ECONOMISCHE GROEI VOOR DE ELAt REGIO BNP BNP/Actief 6 mi inwoners 2,9 mi actief 157 Bi € 54.000 520.000 HTW (1/5) 32 Bi € 6,4% 61.000 7,5% 6 mi inwoners 2,9 mi actief 167 Bi € 58.000 700.000 HTW (1/4) 42 Bi € 61.000 M.Hinoul
  • 68. HIGH TECH SYSTEMS & MATERIALEN Specialisatie en pieken: Selectie en typologie belangrijkste actoren Nederlandse DSP Valley Vereniging Sirris voor Precisie- Vereniging technologie TTR Nederland van de Walonie Espace TTR België Nederlandse DAF nv Graco Chemische Industrie Siemens VDO Vista nv FMTC (mechatronica) Kenniscentra en Philips Alro Holdings centers of excellence Chemelot Ford Werke Bosch Bosch Hydraulic Packaging Borealis Polymers LAG Akzo Nobel Trailers FLAMAC Netherlands Epiq (materialen Aerospace Campus KUL onderzoek) Nedcar Geleen Pure innovatieve Group (NAG) Imec DOW Belgium Vanderlande KUleuven Spaas bedrijven ATC DSM Philips UImec Hasselt Kaarsen Eindhoven Industries Campus Agoria ASML Eindhoven U Luik U Hasselt Tessenderlo Nederlandse Fraunhofer Institut Luik U chemie Océ Forschungszentrum Jülich Heraeus vereniging Stork food RWTH Electro-Nite voor rubber Hochschule systems en Aachen Niederrhein International en Continental printing Schumag AG kunststoffen Mixed innovatieve Flanders Siempelkamp Philips (licht)/ Philips Oerlikon Textile Drive bedrijven Cerobear Onderzoeksinstituut Trützschler Scheidt & Bachmann Pierberg Prüfcentrum Siemens Verband der FEV transportation Systems Voith Paper Chemischen Verband der Motorentechnik industrie (VCI) Elektrotechnik 3M (VDE) AUNDE Cluster Chemie/ Kunststoffe Munters Euroform Netwerken* Mitteldeutschland CAR e.V. INTRA e.V. Verbundinitiative Automobil TTR Duitsland Nordrhein-Westfalen (VIA NRW) * Internationaal netwerk: Automotive.net M.Hinoul
  • 69. Enabling The Digital Age(nda) Electronics Industry ~2000 B$/year Chipmaking Industry ~300 B$/year Lithographic Equipment Industry ~10 B$/year DUV/EUV Light Source Industry ~1B$/year M.Hinoul
  • 70. Aachen/Alsdorf System Suppliers Process (Masks, Resist,..) Lightsource Taking light to 70 new dimensions… M.Hinoul
  • 71. The technological challenge: the winner takes it all…? M.Hinoul
  • 74. Printing 1000.000.000 transistors/second towards 13,5nm wavelength EUV-sources Source ASML M.Hinoul
  • 75. Source Integrated with ASML NXE:3100 @ imec M.Hinoul
  • 76. How Partnerships Can Help Closing the loop on system performance The Netherlands within the Euregio Having access to all major IC companies through Imec’s litho partners Germany Creating an ecosystem of specialized module suppliers Becoming a showcase of hightech Fraunhofer for the rest of the world Belgium ILT M.Hinoul
  • 77. How Partnerships Can Help Closing the loop on system performance The Netherlands within the Euregio Having access to all major IC companies through Imec’s litho partners Germany Creating an ecosystem of specialized module suppliers Becoming a showcase of hightech Fraunhofer for the rest of the world Belgium ILT M.Hinoul
  • 78. Lam RESEARCH STMicroelectronics Imec and the World’s Largest Industry Commitment to Semiconductor Research in Partnership M.Hinoul
  • 79. Infrastructures M.Hinoul
  • 80. The Eindhoven HighTech Campus M.Hinoul
  • 81. The DSM – Chemelot High Tech Campus M.Hinoul
  • 82. RWTH Aachen Campus •15 Clusters •10 000 new jobs •2 Billion € investment M.Hinoul
  • 84. Thor Research Park Waterschei M.Hinoul
  • 86. Sart Tilman Liège M.Hinoul
  • 87. The Leuven Research Parks Termunck Haasrode Arenberg M.Hinoul
  • 88. Life Science Cluster Kenniscentra E.S.R.I. Deckers Div Biotest Seralco Benelux Dermat Thrombogenics Centers of Terumo Tigenix ReMynd excellence IDT(RNA-TEC) Europe Dakocytomation BioTie Therapies Corp. Norgine Univ hospitals K.U.Leuven Cochlear Algonomics Rega Institute CEHA M-Elect PatientWeb Lab of Exp. Genetics & Transgenese Autocyte Medvision M4S Europe Benelux Materialise K.U.Leuven Neurogenetics L-MTC QMedit @Medical Techn. MXS VIB IVIA VIGOUR Custom8 Onco Puur innovatieve Conti BPC Methylome bedrijven Fugeia Regenesys Diatos Medicim New Standard Eng. Malaise&co Formac Ortec CMPG Gemengd innovatieve Pharmaceuticals bedrijven Centocor VWR International M.Hinoul
  • 89. LIFE SCIENCES & MEDISCHE TECHNOLOGIE Specialisatie en pieken: Selectie en typologie belangrijkste actoren TTR Nederland LifeTec Network Flanders’Bio TTR België Technomed Helvoet Pharma Life Life Science Sciences Platform Limburg Supra Polix Tosoh Kenniscentra en (LIOF) Bioscience centers of excellence Kingfisher Occam Philips Medical Thromb-X Healthcare Systems OncoMethylome Pamgene Medtronic Spronken KUL Neurgenetics Orthopedie BioLiege Healthcare & Pie Medical AZ Maastricht VIB Technology Pure innovatieve Knowledge BIOMED Medinvest KUleuven Ortec bedrijven Network Blue U Maastricht U Hasselt Silicos Medical Imec Akzo Nobel/ TU UZ Leuven Organon Eindhoven U Hasselt Centocor IMEC Kath. FH U Luik Pharma BioWin NRW Neuro RWTH Forschungszentrum Boost Terumo Human DSM Notox Aachen Jülich (IME) Europe Health UK Aachen Abiomed Mixed innovatieve Dräger Europe Gmbh bedrijven Activ Care Medical transcon Gmbh Grünenthal Spectaris Bioriver Life DASGIP AG Science Cluster Pharma Aldenhoven Trommsdorff LifeTec Aachen- Jülich Tri-nationale MaasRijn triangle cluster MetNet NRW Netwerken* Bundesverband der Pharmazeutischen Aachener TTR Duitsland Industrie e.v. (BPI) Kompetenzzentrum Medizintechnik AKM *Alma-grid: LSMT samenwerkingsproject Luik, Hasselt, Maastricht, Aken M.Hinoul *Heartbeat: INTERREG III initiatief MaasRijn triangle
  • 90. Networks M.Hinoul
  • 91. Bio-incubators and alliances Novartis Merck Serono Roche P&G Roche Bio-incubators Pfizer 212 Centocor J&J GSK M.Hinoul
  • 93. Health Axis Europe M.O.U. Signed in Leuven © K.U.Leuven - Rob Stevens Leuven, June 8th, 2011 M.Hinoul
  • 94. Structure Leuven Sub-Committee (10) Health Axis Europe Committee (10+10+10) Executive Board (3+3+3) Cambridge Heidelberg Sub-Committee Sub-Committee (10) (10) M.Hinoul
  • 95. Leuven Sub-Committee Members Prof. Dr. Minne Casteels* Prof. Dr. Koenraad Debackere* Vice rector of the Biomedical Sciences Managing Director, KU Leuven Group, KU Leuven Prof. Dr. Frank Luyten Prof. Dr. Piet Stinissen Head of the Division of Rheumatology, Dean of the Faculty of Medicine and University Hospitals Leuven Life Sciences, Hasselt University M.B.A Koen De Leuven M.B.A. Johan Van Witte Sub-Committee Helleputte* Managing Director, reMYND Senior Vice President Strategic Development Unit, imec Dr. Patrik De Haes Prof. Dr Mark Waer Chief Executive Officer, Rector, KU Leuven ThromboGenics Dr. Bart Haex Dr. Patrick Chaltin Strategic Development Managing Director, CD3 * Member of Health Axis Europe Executive Board M.Hinoul
  • 103. Success factors  Cutting-edge science and technology  Tradition in technology transfer  An innovative business climate with high-tech companies and state- of-the-art incubators & science parks  Seed capital, venture capital, growth capital , access to capital markets  Talent  Networking opportunities  International affiliations M.Hinoul
  • 104. Contact KU Leuven Research & Development (LRD) Waaistraat, 6 3000 Leuven, Belgium +32 16 32 65 00 lrd@kuleuven.be lrd.kuleuven.be