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Immunity

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The Immune System Chapter 15 www.freelivedoctor.com
Defense Mechanisms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Defense Mechanisms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Defense Mechanisms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
The Players ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
The Players ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Nonspecific Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Nonspecific Immunity: MB ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Nonspecific Immunity: MB ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Nonspecific Immunity: cells and chemicals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Nonspecific Immunity: cells and chemicals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Nonspecific Immunity: cells and chemicals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Nonspecific Immunity: cells and chemicals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Phagocytosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Phagocytosis ,[object Object],www.freelivedoctor.com
Phagocytosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Phagocytosis ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Phagocytes Intracellular killing of microbes Regulate inflammation Extracellular killing Activation of clotting or anti-clotting Hormonal regulation Chemical secretion www.freelivedoctor.com
Natural Killer (NK) Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Inflammatory Response ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Inflammatory Response ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Local Inflammation ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Local Inflammation ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Local Inflammation ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Local Inflammation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Antimicrobial Substances ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Complement ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Complement Proteins ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Activated Complement Proteins Direct destruction by MAC (membrane attack complex) Vasodilation Increased capillary permeability Chemotaxis Opsinization (antibodies stimulate phagocytosis) www.freelivedoctor.com
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Complement Types www.freelivedoctor.com
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Complement Types www.freelivedoctor.com
Complement Fixation ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Complement Fixation ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Complement Fixation ,[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
Complement Fragments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Interferon ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Fever ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Nonspecific Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Adaptive (Specific) Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Adaptive (Specific) Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Adaptive (Specific) Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Adaptive (Specific) Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Antigens ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Haptens ,[object Object],[object Object],www.freelivedoctor.com
Immunoassays ,[object Object],[object Object],www.freelivedoctor.com
Lymphocytes ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
B Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
Antibodies ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Antibodies www.freelivedoctor.com Immunoglobulin Functions lgG Main form of antibodies in circulation: production increased after immunization; secreted during secondary response lgA Main antibody type in external secretions, such as saliva and mother’s milk lgE Responsible for allergic symptoms in immediate hypersensitivity reactions lgM Function as antigen receptors on lymphocyte surface prior to immunization; secreted during primary response lgD Function as antigen receptors on lymphocyte surface prior to immunization; other functions unknown
Antibody Structure ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Active Immunity ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Active Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
Clonal Selection Theory ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Clonal Selection Theory ,[object Object],[object Object],www.freelivedoctor.com
Passive Immunity ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Passive Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Monoclonal Antibodies ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
T Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Killer (cytotoxic) T Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Helper T Cells ,[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
Suppressor T Cells ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Lymphokines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Subtypes of Helper T Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Major Histocompatability Complexes (MHC) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Major Histocompatability Complexes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Major Histocompatability Complexes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
Destruction of T Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tumor Immunology ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Immunotherapy for Cancer ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Diseases Caused by the Immune System ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Autoimmunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Autoimmunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Immune Complex Diseases ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Immediate Hypersensitivity ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

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Immunity

  • 1. The Immune System Chapter 15 www.freelivedoctor.com
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  • 19. Phagocytes Intracellular killing of microbes Regulate inflammation Extracellular killing Activation of clotting or anti-clotting Hormonal regulation Chemical secretion www.freelivedoctor.com
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  • 30. Activated Complement Proteins Direct destruction by MAC (membrane attack complex) Vasodilation Increased capillary permeability Chemotaxis Opsinization (antibodies stimulate phagocytosis) www.freelivedoctor.com
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  • 54. Antibodies www.freelivedoctor.com Immunoglobulin Functions lgG Main form of antibodies in circulation: production increased after immunization; secreted during secondary response lgA Main antibody type in external secretions, such as saliva and mother’s milk lgE Responsible for allergic symptoms in immediate hypersensitivity reactions lgM Function as antigen receptors on lymphocyte surface prior to immunization; secreted during primary response lgD Function as antigen receptors on lymphocyte surface prior to immunization; other functions unknown
  • 55.
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