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Biochemistry
• Study of chemical composition and
  reactions occurring in living matter
• Inorganic Compounds
     • Do not contain carbon
     • Exceptions - CO2, CO, bicarbonates
     • Water is the most abundant and important
       inorganic material, making up 60% - 80% of all
       cells and 2/3 of body weight
Organic Compounds
• Contain the element
  carbon, hydrogen and
  oxygen.

• Carbon is found in
  things that are or
  once were living.

• Carbon atoms share
  electrons to form
  covalent bonds.
Organic Compounds
• Organic compounds are composed of
  hundreds to thousands of individual
  molecules.
  – The single molecules in a polymer are called
    monomers.
Organic Compounds
• The long molecules formed by repeating
  patterns of monomers are called
  polymers.
Functional Groups
• A functional group is a group of atoms that
  characterize the structure of a family of
  organic compounds.
• Functional groups determine many of the
  properties of organic compounds.
• 3 Types to Know: Amine (NH2), Carboxyl
  (COOH), Hydroxyl (OH).
Amine Group



N-H2

                Functional Groups
Carboxyl Group



COOH

              Functional Groups
Hydroxyl Group



OH


             Functional Groups
Macromolecules
• 4 Types of Organic Compounds or
  macromolecules: carbohydrates, lipids,
  proteins, and nucleic acids.
  – Essential to maintaining life processes: cell
    function, storage, energy, homeostasis and
    genetic information.
Carbohydrates
• Make up sugars and   • The ratio of the atoms
  starches               is 1 C : 2 H : 1 O
• Contain a hydroxyl   • Provide energy to the
  (OH) group             cells.
• Contain atoms of
                       • Dissolve in water
  carbon, hydrogen,
  and oxygen.            (hydrophilic)
Types of Carbohydrates
• Carbohydrates are classified according
  to size.
     • One sugar is a monosaccharide
       (monomer).
     • Two sugars make a disaccharide.
     • Many sugar molecules linked together form
       a polysaccharide (polymer).
Monosaccharide
Milk Sugar   Fruit Sugar




                       Types of Carbs
Disaccharide




Maltose is two glucose molecules; forms in digestive tract of
             humans during starch digestion.

                                                     Types of Carbs
Polysaccharide




Starch is straight chain of glucose molecules with few side
                         branches.




                                               Types of Carbs
Lipids
• The three types of       • Glycerol contains the
  lipids are fats, oils,     hydroxyl (OH) group.
  and waxes.               • Fatty acids contain
• Contain carbon,            the carboxyl (COOH)
  hydrogen, and              group.
  oxygen
• Typically contain two
  monomers –
  glycerol and fatty acids
Monomers in Lipids




                     Lipids
Functions of Lipids
• Lipids store energy    • Lipids do not
  for later use by the     dissolve in water
  body.                    (hydrophobic), but
• Lipids also serve        may contain parts
  as padding and           that can dissolve in
  protection for the       water.
  body.                  • The H : O ratio is
                           higher in lipids than
                           it is in
                           carbohydrates.
Structure of a Lipid
• Dissolves in
  water (
  hydrophilic)




• Does not
  dissolve in
  water
  (hydrophobic)
Phospholipid
• Found in cell
  membranes
  – Head is the
    phosphate
    group.
      • Hydrophilic
  – Tails are the
    fatty acids.
      • Hydrophobic
Fatty Acids
• Long chains of carbon atoms with
  attached hydrogen atoms (hydrocarbons)
• Saturated fats contain only single bonds
  between the carbon atoms.
• Unsaturated fats contain one or more
  double or triple bonds between the carbon
  atoms.
Saturated & Unsaturated Fats
Proteins
• Proteins are the building materials for the
  body.
  – Hair, skin, muscles, and organs are made
    mostly of proteins.
• Composed of carbon, hydrogen, nitrogen,
  and oxygen
• Contain amine (NH2) and carboxyl (COOH)
  groups
Function of Proteins
• The building blocks of      • Amino acid chains are
  proteins are amino acids      called polypeptides.
  (monomers).                 • A protein contains one or
• Serve as enzymes which        more polypeptide chains.
  control rate of reactions
  and regulate cell
  processes.
• Amino acids are
  connected by a special
  type of bond called a
  peptide bond.
Amino Acids




              Function of Proteins
Types of Proteins
• There are two types of proteins –
  fibrous and globular.
• Fibrous protein (found in skin, tendons,
  bones, and muscles) does not dissolve
  in water (hydrophobic).
• Globular protein (found in enzymes,
  some hormones, and hemoglobin) can
  dissolve in water (hydrophilic).
Fibrous Proteins
• Keratins are a family
  of
  fibrous structural proteins
  ; tough and insoluble,
  they form the hard but
  nonmineralized
  structures found in
  reptiles, birds,
  amphibians and
  mammals.
                                Types of Proteins
Globular Proteins
• Enzymes are
  proteins that catalyze
  (i.e. accelerate)
  chemical reactions.
• Almost all processes
  in a biological cell
  need enzymes in
  order to occur at
  significant rates.

                           Types of Proteins

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Structure of organic compounds

  • 1. Biochemistry • Study of chemical composition and reactions occurring in living matter • Inorganic Compounds • Do not contain carbon • Exceptions - CO2, CO, bicarbonates • Water is the most abundant and important inorganic material, making up 60% - 80% of all cells and 2/3 of body weight
  • 2. Organic Compounds • Contain the element carbon, hydrogen and oxygen. • Carbon is found in things that are or once were living. • Carbon atoms share electrons to form covalent bonds.
  • 3. Organic Compounds • Organic compounds are composed of hundreds to thousands of individual molecules. – The single molecules in a polymer are called monomers.
  • 4. Organic Compounds • The long molecules formed by repeating patterns of monomers are called polymers.
  • 5. Functional Groups • A functional group is a group of atoms that characterize the structure of a family of organic compounds. • Functional groups determine many of the properties of organic compounds. • 3 Types to Know: Amine (NH2), Carboxyl (COOH), Hydroxyl (OH).
  • 6. Amine Group N-H2 Functional Groups
  • 7. Carboxyl Group COOH Functional Groups
  • 8. Hydroxyl Group OH Functional Groups
  • 9. Macromolecules • 4 Types of Organic Compounds or macromolecules: carbohydrates, lipids, proteins, and nucleic acids. – Essential to maintaining life processes: cell function, storage, energy, homeostasis and genetic information.
  • 10. Carbohydrates • Make up sugars and • The ratio of the atoms starches is 1 C : 2 H : 1 O • Contain a hydroxyl • Provide energy to the (OH) group cells. • Contain atoms of • Dissolve in water carbon, hydrogen, and oxygen. (hydrophilic)
  • 11. Types of Carbohydrates • Carbohydrates are classified according to size. • One sugar is a monosaccharide (monomer). • Two sugars make a disaccharide. • Many sugar molecules linked together form a polysaccharide (polymer).
  • 12. Monosaccharide Milk Sugar Fruit Sugar Types of Carbs
  • 13. Disaccharide Maltose is two glucose molecules; forms in digestive tract of humans during starch digestion. Types of Carbs
  • 14. Polysaccharide Starch is straight chain of glucose molecules with few side branches. Types of Carbs
  • 15. Lipids • The three types of • Glycerol contains the lipids are fats, oils, hydroxyl (OH) group. and waxes. • Fatty acids contain • Contain carbon, the carboxyl (COOH) hydrogen, and group. oxygen • Typically contain two monomers – glycerol and fatty acids
  • 17. Functions of Lipids • Lipids store energy • Lipids do not for later use by the dissolve in water body. (hydrophobic), but • Lipids also serve may contain parts as padding and that can dissolve in protection for the water. body. • The H : O ratio is higher in lipids than it is in carbohydrates.
  • 18. Structure of a Lipid • Dissolves in water ( hydrophilic) • Does not dissolve in water (hydrophobic)
  • 19. Phospholipid • Found in cell membranes – Head is the phosphate group. • Hydrophilic – Tails are the fatty acids. • Hydrophobic
  • 20. Fatty Acids • Long chains of carbon atoms with attached hydrogen atoms (hydrocarbons) • Saturated fats contain only single bonds between the carbon atoms. • Unsaturated fats contain one or more double or triple bonds between the carbon atoms.
  • 22. Proteins • Proteins are the building materials for the body. – Hair, skin, muscles, and organs are made mostly of proteins. • Composed of carbon, hydrogen, nitrogen, and oxygen • Contain amine (NH2) and carboxyl (COOH) groups
  • 23. Function of Proteins • The building blocks of • Amino acid chains are proteins are amino acids called polypeptides. (monomers). • A protein contains one or • Serve as enzymes which more polypeptide chains. control rate of reactions and regulate cell processes. • Amino acids are connected by a special type of bond called a peptide bond.
  • 24. Amino Acids Function of Proteins
  • 25. Types of Proteins • There are two types of proteins – fibrous and globular. • Fibrous protein (found in skin, tendons, bones, and muscles) does not dissolve in water (hydrophobic). • Globular protein (found in enzymes, some hormones, and hemoglobin) can dissolve in water (hydrophilic).
  • 26. Fibrous Proteins • Keratins are a family of fibrous structural proteins ; tough and insoluble, they form the hard but nonmineralized structures found in reptiles, birds, amphibians and mammals. Types of Proteins
  • 27. Globular Proteins • Enzymes are proteins that catalyze (i.e. accelerate) chemical reactions. • Almost all processes in a biological cell need enzymes in order to occur at significant rates. Types of Proteins

Hinweis der Redaktion

  1. Identify the important facts regarding inorganic molecules.
  2. Have students differentiate between organic and inorganic compounds.
  3. The images at the bottom are examples of monomers. Explain to the students that fructose is a simple sugar. The string of beads are also an example of monomers. As the beads are all the same in the string.
  4. Compare the structure of the monomers to the polymers. Use the InterWrite tablet to identify the bonds for students.
  5. Use the interactive links to show the diagrams of each functional group.
  6. Use InterWrite tablet to a place circle around the functional group.
  7. Identify the double bonds, in the carboxyl group.
  8. Circle the hydroxyl group in the sugar molecule. Use the InterWrite tablets.
  9. Students are to list all of the reasons why macromolecules are essential to life on their Cornell note sheet. Please allow time for this.
  10. Emphasize the importance of carbohydrates to living things.
  11. Use image to discuss the structure of the two simple sugars and their molecular formula C 6 H 12 O 6. Use the InterWrite tablet to circle the functional group.
  12. Differentiate between the simple sugars and the complex sugar. Again, emphasize the structure and molecular formula C 12 H 22 O 11. Use the InterWrite tablets to circle the functional group.
  13. Identify the structure of the polysaccharide. Highlight for students how the long chains of monomers form this polymer. Also, use the InterWrite tablets to circle the functional group.
  14. Emphasize the three types of lipids. Click link for glycerol and fatty acids to show a diagram of the two structures. Use InterWrite tablets to circle the functional group.
  15. Discuss the differences between the glycerol and the fatty acids chain.
  16. Identify the functions of the lipids. Make sure students have the same information on their Cornell note sheet.
  17. Use this slide to discuss the hydrophilic and hydrophobic ends of the lipid molecule. The link will also take you to an image of the phospholipid bilayer.
  18. Explain to the students how the phosholipid bilayer works.
  19. Differentiate between saturated and unsaturated fats.
  20. Explain the structure.
  21. Identify the functions of proteins.
  22. Additional functions for review. Use the link to an example of three different types of amino acids and a peptide bond.
  23. Identify the three amino acids. Explain how they come together to form the peptide bond.
  24. This slide is optional. Use if you would like your students to have this additional information regarding proteins. It is also linked to examples of each type of protein.
  25. Optional
  26. Optional