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Organ Detection in Fetal MRI
Kevin Keraudren
Imperial College London

May 22nd , 2013
1

Overview

2

Python interface for IRTK

3

Future work

2/27
1

Overview

2

Python interface for IRTK

3

Future work

3/27
Overview

1

Brain detection &
reconstruction

2

3D visualisation

3

Organ localisation

4/27
People

Brain reconstruction:
Maria Murgasova
3D visualisation:
Christina Malamateniou
Organ detection:
Bernhard Kainz

5/27
Localisation of the Brain in Fetal MRI Using
Bundled SIFT Features

For every slice

Detect MSER regions

Filter by size

RANSAC

Classify using SIFT features

6/27
Detections results averaged over the cross
validation (all orientations combined)
Centiles
25th
50th
75th

2D SIFT
10.9
15.5
20.5

Error (mm)
3D SIFT
14.8
20.8
30.4

Bundled SIFT
4.0
5.7
8.4

Detection
Complete brain

98%
38%

85%
23%

100%
85%

7/27
1

Overview

2

Python interface for IRTK

3

Future work

8/27
Why Python?

ls *.nii | python -c ’import sys, irtk;
[sys.stdout.write( str(irtk.imread(line.rstrip(),
dtype="float32").max())+"n")
for line in sys.stdin]’

numpy, matplotlib, OpenCV, VTK, scipy.ndimage...
& C++ via cython

9/27
Why another library?
import itk
pixelType = itk.UC
imageType = itk.Image[pixelType, 3]
readerType = itk.ImageFileReader[imageType]
writerType = itk.ImageFileWriter[imageType]
reader = readerType.New()
reader.SetFileName( "input.nii" )
reader.Update()
itk2np = itk.PyBuffer[imageType]
data = itk2np.GetArrayFromImage( reader.GetOutput() )
...
10/27
Why another library?
import SimpleITK as sitk
img = sitk.ReadImage( "input.nii" )
data = sitk.GetArrayFromImage( img )
...
output = sitk.GetImageFromArray( data )
output.SetSpacing( img.GetSpacing() )
output.SetOrigin( img.GetOrigin() )
output.SetDirection( img.GetDirection() )
sitk.WriteImage( output, "output.nii" )

11/27
Why another library?

import irtk
img = irtk.imread( "input.nii" )
...
irtk.imwrite( "output.nii", img )

12/27
Key features

simple and pythonic
overload getitem instead of GetRegion
parallelisation using joblib
visualisation functions

13/27
Implementation

template <class dtype>
void irtk2py( irtkGenericImage<dtype>& irtk_image,
dtype* img,
double* pixelSize,
double* xAxis,
double* yAxis,
double* zAxis,
double* origin,
int* dim );
14/27
Implementation

void py2rigid( irtkRigidTransformation &transform,
double tx,
double ty,
double tz,
double rx,
double ry,
double rz,
bool invert=false );

15/27
Demo

ipython notebook

16/27
Parallelisation example





















import irtk
from joblib import Parallel, delayed
from glob import glob
def register( f, img1):
img2 = irtk.imread( f, dtype=’float32’)
img2 = img2.rescale().resample(2)
t = img2.register(img1)
return t
filenames = glob( raw_folder + "/" + patient_id + "_*.nii")
img1 = irtk.imread(filenames[0], dtype=’float32’)
img1 = img1.rescale().resample(2)
transformations = [irtk.RigidTransformation()]
transformations.extend( Parallel(n_jobs=-1)(delayed(register)(f,
img1)
for f in filenames[1:] )
)

17/27
1

Overview

2

Python interface for IRTK

3

Future work

18/27
Coarse segmentation as side product of detection

19/27
Convex hull of all detections

20/27
Iterative detection/reconstruction

21/27
Iterative detection/reconstruction

22/27
Iterative detection/reconstruction

23/27
Room for improvement

Refine motion model (statistics on slice transformations)
Patch based segmentation instead of graphcut
Detect head orientation to solve more difficult registrations

Could the detection process produce
more than a mask?

24/27
Could we reconstruct more than the brain?

25/27
For the future (hanging projects)
Spine detection using SLIC supervoxels

Dense volumetric features: SURF 3D

Alignment of mothers’ bodies to model of a pregnant woman
26/27
Suggestions or questions?

27/27

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Reading group - 22/05/2013