The development of a new active substance is not just about developing a better molecule with biological activity. http://www.mahendrachemicals.com/

1. pharmaceutical manufacturer
Pharmaceutical Development Financial Success
The development of a new active substance is not just about developing a better molecule with
biological activity. The physical form must be optimized to ensure the highest possible performance and
you cannot find a superior and steal your hard earned patent position.
Development of pharmaceuticals is the progression of a new chemical entity is in early detection
through subsequent stages of clinical development. Drug development includes the construction of a
manufacturing process and scalable refinement optimum physical form the active pharmaceutical
ingredient (API).
Drug development begins with an active compound which shows the desired response in an assay.
However, in vivo (in the body), the compound could not get to the point of action as he did so easily in
vitro (literally, in glass). Pharmaceutical development is needed to convert the compound into a form
that is stable, biologically available and can be converted into the more favorable formulation.
Requires a balance between the lipophilicity and water solubility (ability to dissolve in fats)
characteristics of the drug. Scientific experts will be able to convert a compound with poor physical
properties in one that can be crystallized and processed effectively. A screen will result salt candidate
compounds can be selected and subsequently be further optimized. You will need to be made between
performance and drug manufacture a balance.
It is essential to integrate manufacturing experience with solid experience with a wide range of
equipment state - of-the -art facilities and operating current standards of Good Manufacturing.
Production scale and kilo quantities of drugs under full GMP pharmaceutical development phase soon. If
done properly, the optimal fitness will be carried out together with the means to manufacture.
Ultimately intellectual property will be insured and the long-term financial success guaranteed.
Mahendra Chemicals is an US FDA approved ISO 9001:2008 certified active pharmaceutical ingredients
suppliers and lidocaine hydrochloride suppliers and ability to synthesize new API, Local Anesthetics.