Biodegradable Polymeric by 이흐완 히다얏

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Ikhwan Hidayat

Technologie Business

Contents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Applications ,[object Object],[object Object],[object Object],[object Object],Figure 1. Biodegradable intravascular stent

Poly( α -esters) ,[object Object],[object Object],[object Object],[object Object],Figure 2. Polyester based, meniscus repair devices

Polyglycolide (PGA) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Polylactides (PLA) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Poly( ε -caprolactone) (PCL) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Other Polymers under Development ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Biodegradation Mechanism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Packaging ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

“ Biomimetic calcium phosphate coating on electrospun- poly( ε -caprolactone) scaffolds for bone tissue engineering” ,[object Object],[object Object],[object Object],By: F. Yang, J.G.C. Wolke, J.A. Jansen

[object Object],[object Object],characterization ,[object Object],[object Object],[object Object],[object Object],[object Object]

Appendix a. Properties of common biodegradable polymers Polymer Melting Point (°C) Glass-Transition Temp (°C) Modulus (Gpa) a Degradation Time (months) b PGA 225—230 35—40 7.0 6 to 12 PLLA 173—178 60—65 2.7 >24 DLLA Amorphous 55—60 1.9 12 to 16 PCL 58—63 (—65)— (—60) 0.4 >24 PDO N/A (—10)— 0 1.5 6 to 12 PGA-TMC N/A N/A 2.4 6 to 12 85/15 DLPLG Amorphous 50—55 2.0 5 to 6 75/25 DLPLG Amorphous 50—55 2.0 4 to 5 65/35 DLPLG Amorphous 45—50 2.0 3 to 4 50/50 DLPLG Amorphous 45—50 2.0 1 to 2 a Tensile or flexural modulus. b Time to complete mass loss. Rate also depends on part geometry.

Appendix b. Commercial biodegradable medical products Application Trade Name Composition a Manufacturer Dexon PGA Davis and Geck Maxon PGA-TMC Davis and Geck Vicryl PGA-LPLA Ethicon Sutures Monocryl PGA-PCL Ethicon PDS PDO Ethicon Polysorb PGA-LPLA U.S. Surgical Biosyn PDO-PGA-TMC U.S. Surgical PGA Suture PGA Lukens Sysorb DLPLA Synos Endofix PGA-TMC or LPLA Acufex Arthrex LPLA Arthrex Interference screws Bioscrew LPLA Linvatec Phusiline LPLA-DLPLA Phusis Biologically Quiet PGA-DLPLA Instrument Makar Suture anchor Bio-Statak LPLA Zimmer Suretac PGA-TMC Acufex Anastomosis clip Lactasorb LPLA Davis and Geck Anastomosis ring Valtrac PGA Davis and Geck Dental Drilac DLPLA THM Biomedical Angioplastic plug Angioseal PGA-DLPLA AHP Screw SmartScrew LPLA Bionx Pins and rods Biofix LPLA or PGA Bionx Resor-Pin LPLA-DLPLA Geistlich Tack SmartTack LPLA Bionx Plates, mesh, screws LactoSorb PGA-LPLA Lorenz

감사합니다 ,[object Object],[object Object],[back to index of contents] mail to: ikhwan4ever@gmail.com

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Biodegradable Polymeric by 이흐완 히다얏

1. Biodegradable Polymeric Biomaterial Presented by: Ikhwan Hidayat ( 이흐완 히다얏 )

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15. Appendix a. Properties of common biodegradable polymers Polymer Melting Point (°C) Glass-Transition Temp (°C) Modulus (Gpa) a Degradation Time (months) b PGA 225—230 35—40 7.0 6 to 12 PLLA 173—178 60—65 2.7 >24 DLLA Amorphous 55—60 1.9 12 to 16 PCL 58—63 (—65)— (—60) 0.4 >24 PDO N/A (—10)— 0 1.5 6 to 12 PGA-TMC N/A N/A 2.4 6 to 12 85/15 DLPLG Amorphous 50—55 2.0 5 to 6 75/25 DLPLG Amorphous 50—55 2.0 4 to 5 65/35 DLPLG Amorphous 45—50 2.0 3 to 4 50/50 DLPLG Amorphous 45—50 2.0 1 to 2 a Tensile or flexural modulus. b Time to complete mass loss. Rate also depends on part geometry.

16. Appendix b. Commercial biodegradable medical products Application Trade Name Composition a Manufacturer Dexon PGA Davis and Geck Maxon PGA-TMC Davis and Geck Vicryl PGA-LPLA Ethicon Sutures Monocryl PGA-PCL Ethicon PDS PDO Ethicon Polysorb PGA-LPLA U.S. Surgical Biosyn PDO-PGA-TMC U.S. Surgical PGA Suture PGA Lukens Sysorb DLPLA Synos Endofix PGA-TMC or LPLA Acufex Arthrex LPLA Arthrex Interference screws Bioscrew LPLA Linvatec Phusiline LPLA-DLPLA Phusis Biologically Quiet PGA-DLPLA Instrument Makar Suture anchor Bio-Statak LPLA Zimmer Suretac PGA-TMC Acufex Anastomosis clip Lactasorb LPLA Davis and Geck Anastomosis ring Valtrac PGA Davis and Geck Dental Drilac DLPLA THM Biomedical Angioplastic plug Angioseal PGA-DLPLA AHP Screw SmartScrew LPLA Bionx Pins and rods Biofix LPLA or PGA Bionx Resor-Pin LPLA-DLPLA Geistlich Tack SmartTack LPLA Bionx Plates, mesh, screws LactoSorb PGA-LPLA Lorenz

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Biodegradable Polymeric by 이흐완 히다얏

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