The document summarizes key concepts in pharmacokinetics relevant to anesthesiologists, including: 1) Partial pressure gradients exist from the anesthetic machine to the brain, with the alveolar partial pressure determining brain tissue partial pressure. 2) Inflow factors like gas flow rate and breathing systems influence the delivered anesthetic concentration. Outflow factors like solubility and pulmonary blood flow influence loss from alveoli. 3) Equilibrium is reached when partial pressures are equal between gas and dissolved phases, with more soluble agents reaching equilibrium faster but also being more affected by changes in ventilation and blood flow.

1. PHARMACOKINETICS OF INHALATIONAL AGENTS RELAVANT TO ANAESTHEIST

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