GSK is implementing an internal innovation strategy focused on developing new drugs through 70 Drug Product Units (DPUs) working across 8 therapy areas. This reorganization presents both opportunities and challenges for GSK. Critical issues include cultivating a collaborative culture, incentivizing innovation, focusing on new product development as patents expire, and ensuring effective communication and resource allocation across the decentralized DPU structure. Special programs will be needed to address increased competition between DPUs, potential fears or inertia among employees, and risks around staff retention and confidentiality. GSK will also need to closely evaluate strategic alignment, customer and supplier relationships, organizational structures and processes, new product pipelines, and customer satisfaction to guide innovation efforts and ensure goals are met. Financial,
2. Fear: The DPUs are already half way through their three years budget they were given in 2008, the clock is ticking on their scientists (Whalen, 2010); it may create fear of being sacked and affect their morale and performance. Contrastingly the contextual confrontation may give a boost to innovation also.
3. Inertia: Individuals who are used to a bureaucratic system and an old mind set may find it very hard to take ownership of decisions in the new set up of small autonomous DPUs. Perry Nisen, a cancer research chief at Glaxo, said in an interview “everyday people come to me and say, “what do you think I should do? Everyday for me, it’s ‘well that’s your decision. What do you want to do?” (Whalen, 2010). Changing the mind set of people to overcome the inertia and accept change will remain a challenge with management.
4. Bureaucratic systems: Now as the CEDDs are further divided into small units of DPUs, it forms one more layer in the already bureaucratic structure of GSK. Hence making the implementation and reporting process even more complex.
5. Staff Retention: The revised structure of DPUs is similar to those of small Biotech firms. However, according to Denise Anderson, a healthcare analyst at SIT investment associate in Minneapolis, “Problem with big companies trying to act like biotech is that people who like the really entrepreneurial culture of a biotech go to biotech”. This may also be due to better incentives offered by small companies (Whalen, 2010). It poses a serious problem to GSK in staff hiring and retention.
6. Communication: As the DPUs work on different parts of the pipeline associated with the production of a drug, the smooth flow of information following coordination among them becomes crucial. Duplication of work needs to be avoided at the same time sharing of knowledge and ideas to be encouraged. A compound discovered in one unit might not be useful for them but may be useful for another unit’s research process and may leverage breakthrough in another therapy area.
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8. Customer and Supplier network: Examining the network with customers, suppliers, regulators etc is also critical to GSK’s success. In pharmaceutical industry the prime customer is the doctor who prescribes the medicine. The quantitative and qualitative level of the network with doctors, suppliers and regulators needs to be evaluated on regular basis.
9. Information System of firm: Communication and information system of the firm need to be evaluated. The information systems should support timely and accurate communication reaching to right people. This is crucial to a firm’s success as it may result in quicker and effective ideas sharing culture and increased operational efficiency.
10. Organizational Structure and Communication: With an extensive framework of 70 DPUs working together towards innovation, there is a need of evaluating the exhisting organizational structure and communication processes. A classic example of how the communication system failed to address problems prevailing is, when GSK’s Cidra, Puerto Rico facility had to be closed down in 2009 due to quality concerns. The then GSK manager of Global Quality assurance, Cheryl Eckard, noticed serious production issues including broken facility, broken equipments, production line failures, medication mix ups, wrongly measures active ingredients, incorrect packaging and wrong handling by employees etc. at the facility. She reportedly informed everything to the vice president for quality and asked to take certain measures but there was a clear communication gap which she shared in an interview on “60 minutes” reporting all these issues. This incident sent a very negative image of GSK in the market and industry (Megget, 2011).GSK admitted the manufacturing malfunction saying it was “inconsistent with GSK’s commitment to manufacturing quality”(www.gsk.com).
15. how many new products or improvised existing products have been introduced,
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17. White M A and Bruton G D, 2007, ‘The management of technology and innovation: a strategic approach’, 1st edition, Thomson South-western press, Canada.
18. Whalen J, 2010, ‘Glaxo tries BioTech Model to Spur Drug Innovations’, The Wall Street Journal, pp1-2, available at