Uses of inexpensive, personal, commercially-available, and portable EEG devices for medical research. Testing of new drugs, patient-specific drug selection, monitoring of patient progress, augmentation of treatments (via neurofeedback), prediction of 'attacks' in mental illnesses (e.g. panic disorder), and better diagnoses of neurological disorders.
6. PND technologies: Amygdala
ď Backend for non-game
mobile EEG software
ď Streamlines mobile EEG
development
ď Algorithms, built-in GUIs,
links to BackupBrain, etc.
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9. Introspect
ď Detects: (e.g.)
ď Mood
ď Anxiety
ď Stress
ď Acute cognitive
functioning
ď Sleep quality Example waveforms
linked to mental states
ď Concentration
ď Pain âunpleasantnessâ
10. Introspect
ď Detects problem areas
ď Built-in neurofeedback exercises to
improve specific areas
PND neurofeedback game:
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11. Neurofeedback
ď Training to directly
alter EEG output
ď Mindfulness-based
ď Meditation
ď Effective treatment
ď ADHD
ď depression
ď Anxiety
ď etc.
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12. PND: Pharmaceutical uses
ď Based on adaptations of Introspect
ď Introspect malleable for
ď Research
ď Diagnostics
ď Treatment
ď Etc.
13. PND: Pharmaceutical uses
1) New drug testing
ď mobile real-time drug efficacy monitoring
ď E.g. observe mood in brain over time
14. PND: Pharmaceutical uses
2) Aid patient-specific
drug selection
ď EEG patterns linked to
disorder etiologies
ď Help hospital funding
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15. PND: Pharmaceutical uses
3) Monitor patient progress
ď Ensure continued symptom
control
ď Change treatments as
needed
Example mood and anxiety chart
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21. References
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cells. PLoS Biol, 4(2): p49.
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Fields. Lippincot Williams & Wilkins.
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training". Electroencephalogr Clin Neurophysiol 33 (1): 89â95
⢠Basic concepts and clinical findings in the treatment of seizure disorders with EEG operant conditioning". Clin
Electroencephalogr 31 (1): 45â55.
⢠Hammond, Corydon D. "Neurofeedback Treatment of Depression and Anxiety." Journal of Adult Development, Vol 12,
Nos. 2/3, August 2005
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⢠Sny-der et al. (2008). Blinded, multi-center val-i-da-tion of EEG and rat-ing scales in iden-ti-fy-ing ADHD within a
clin-i-cal sam-ple. Psy-chi-a-try Research, 159, 346â358
22. References
⢠Caat, M. T., Lorist, M. M., Bezdan, E., Roerdink, J. B., & Mauritis, N. M. (2008). High-Density EEG Coherence Analysis Using
Functional Units Applied to Mental Fatigue. Journal of Neuroscience Methods, 17, pp. 271-278.
⢠Nuwer, M,, et al, (2005). Routine and Quantitative EEG in Mild Traumatic Brain Injury; Clinical Neurophysiology, 116.
⢠Thatcher, R.W., Camacho, M,, Salazar, A, Linden, C., Biver, C. and Clarke, L.: Quantitative MRI of Gray-White Matter
Distribution in Traumatic Brain Injury. Journal of Neurotrauma, Volume 14, No. 1, 1-14, 1997
⢠Thatcher, R.W., Moore, N, John, E.R., et al.: QEEG and Traumatic Brain Injury: Rebuttal of the American Academy of
Neurology 1997. A Report by the EEG and Clinical Neuroscience Society, Clinical Electroencephalography, 30(3): 94-98,
1999
⢠Khodayari-Rostamabad, A., Hasey, G. M., Maccrimmon, D. J., Reilly, J. P., & de Bruin, H. (2010). A pilot study to
determine whether machine learning methodologies using pre-treatment electroencephalography can predict the
symptomatic response to clozapine therapy. Clinical Neurophysiology, 121(12), 1998â2006
⢠Baskaran, A., Milev, R., & McIntyre, R. S. (2012). The neurobiology of the EEG biomarker as a predictor of treatment
response in depression. Neuropharmacology, 63(4), 507â13
⢠Thompson, L. et al (2010). Neurofeedback outcomes in clients with Aspergerâs syndrome. Applied psychophysiology
and biofeedback, 35(1), 63â8
⢠Kouijzer, M., et al. (2009). Neurofeedback Treatment for Autism Spectrum Disorders: Scientific Found- ations and
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More available on request
Hinweis der Redaktion
gamification designers, graphic designersBased out of both san jose and ottawa, linked to Neurosky