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Body Sensor Networks –
Research Challenges and Applications
Professor Guang-Zhong Yang
Institute of Biomedical Engineering
Imperial College London
http://www.bsn-web.org
Acknowledgement
Benny Lo
Eric Yeatman, Louis Atallah
Omer Aziz, Julien Pansiot
Surapa Themajarus
Lei Wang, Mohammad Elhlew
Oliver Wells, Rachel King, Len Fass
Ara Darzi
Imperial College London: basic stats
• 2700 academic and research staff:
6 campuses
• 10,000 students (1/3rd
post-grad)
• 18 Nobel Prize winners
• Faculties of Natural Sciences,
Engineering, Medicine, and
Business School
• Highest research income in UK
universities: £155 million p.a.; also highest
industry funded research in the UK
• Total income: £410 million p.a.
Evolution of computer technologies
Moore's Law
0
1
2
3
4
5
6
7
8
9
1971 1976 1981 1986 1991 1996 2003
Year
Transistors(log)
Estimate Actual
4004
4-bit
108kHz
0.06MIPS
2.3K transistors
1971
8008
108kHz
8-bit
16kB
0.06MIPS
3.5K transistors
1972
8080
8-bit
2Mhz
0.64MIPS
6k transistors
1974
8086
16-bit
8MHz
0.8MIPS
29K transistors
1978
80286
16-bit
12MHz
2.7MIPS
134K transistors
1982
80386
32-bit
20MHz
6MIPS
275K transistors
1985
80486
25MHz
20MIPS
1.2M transistors
1989
Pentium
32-bit
66MHz
100MIPS
3.2M transistors
1993
Pentium II
233MHz
300MIPS
7.5M transistors
1997
Pentium III
450-500MHz
510MIPS
9.5M transistors
1999
Pentium 4
1.4&1.5GHz
1.7GIPS
42M transistors
2000
Pentium M
600Mhz-1.6GHz
6.5GIPS
77M transistors
2003
P4 Prescott
2.8-3.4 GHz
125M transistors
7GIPS
2004
Pentium D
3.2 GHz
15GIPS
230M transistors
2005
4004
8008 8080 8086
80286
80386 80486
Pentium Pentium II
Pentium III
Pentium 4
Pentium M
P4 Prescott
Pentium D
http://www.granneman.com/
http://velox.stanford.edu/group/chips_micropro_body.html
http://home.datacomm.ch/fmeyer/cpu/
http://www.pc-erfahrung.de/Index.html?ProzessormodelleIntelItanium2.html
http://www.pc-erfahrung.de/
http://trillian.randomstuff.org.uk/~stephen/history
http://www.theregister.co.uk/2004/02/02/intel_prescott_90nm_pentium/
http://www.intel.com/products/processor/pentiumm/image.htm
Evolution of computer technologies
Bell’s Law
New computing class every decade
New applications and contents develop around each new class
year
log(peoplepercomputer/price)
WSN – dust
11.7mm3
Solar powered
Bi-directional communications (laser light house)
Sensing (acceleration and ambient light)
Habitat Monitoring:
Great Duck Island Study
In the spring 2002 and in August 2003, Intel Research Lab
Berkeley deployed a large number of wireless sensor network
nodes on Great Duck Island which monitors the microclimates in
and around nesting burrows used by the Leach’s Storm Petrel.
Aimed to develop a habitat monitoring kit for non-intrusive and
non-disruptive monitoring of sensitive wildlife and habitats.
Each mote has a microcontroller, a low-power radio, memory and
batteries.
Temperature, humidity, barometric pressure, and mid-range
infrared sensors were used.
Motes periodically sample and relay their sensor readings to
computer base stations on the island. These in turn feed into a
satellite link that allows researchers to access real-time
environmental data over the Internet.
Location tracking:
MIT - Cricket
Cricket is indoor location system for pervasive and sensor-based computing
environments
Ultrasound sensors are integrated with motes for tracking objects and activities
Provides location information – identify space, position, coordinates and orientation of
the subject – to applications running on handhelds, laptops, and sensor nodes
Intended for indoor usage where outdoor systems like GPS wouldn’t work
Structural Health Monitoring:
Golden gate bridge study
Golden gate bridge is exposed to strong wind and earth quake
Budget for structural monitoring ~US$1,000,000
Accelerometers are used to monitoring the vibration on the bridge
and temperature sensors are integrated to calibrate the
accelerometer against temperature difference
Mote Evolution
Wireless and Body Sensor Networks
Cover the human body
Fewer sensor nodes
Single multitasking sensors
Robust & Accurate
Miniaturization
Pervasive
Predictable environment
Motion artefacts an issue
Early adverse event detection
Failure irreversible
Variable structure
Cover the environment
Large number of nodes
Multiple dedicated sensors
Lower accuracy
Small size not limiting factor
Resistant to weather,
Resistant to noise
Resistant to asynchrony
Early adverse event
detection
Failure reversible
Fixed structure
WSN BSN
Wireless and Body Sensor Networks
Low level security
Accessible power supply
High power demand
Solar,wind power
Replaceable/disposable
No biocompatibility needed
Low context awareness
Wireless solutions available
Data loss less of an issue
High security
Inaccessible power source
Lower power availability
Thermal, piezoelectric energy
Biodegradeable
Biocompatible
High context awareness
Lower power wireless
Sensitive to data loss
WSN BSN
Focus of This Talk
Technical Challenges and Opportunities of
BSN
Healthcare and Wellbeing Monitoring
Sports and Entertainment
Conclusions
Focus of This Talk
Technical Challenges and Opportunities of
BSN
Healthcare and Wellbeing Monitoring
Sports and Entertainment
Conclusions
Biosensor
Design
Biocompatibility
& Materials
Wireless
Communication
Low Power
Design &
Scavenging
Autonomic
Sensing
Standards &
Integration
BSN
WhatdoesBSNCover?
Biocompatibility and Materials
Biosensors
Stents
Tissue Engineering
Pattern and manipulate cells in
micro-array format
Drug delivery
systems
Carol Ezzell Webb, “Chip Shots”, IEEE Spectrum Oct 2004
Smart Pill – Sun-Sentinel Co.
Implant blood pressure
flow sensor (CardioMEMS)
Drug releasing stents -
Taxus stents - Boston Scientific Co.
Ozkan et. al (2003), Langmuir
Biosensor Design
Thermistor
ECG
SpO2
Glucose concentration
Implant blood pressure
flow sensor (CardioMEMS)
Glucose sensor
(Glucowatch)
Thermistor
(ACR system)
Implant ECG recorder
(Medtronics –Reveal)
Oxymeter
(Advanced Micronics)
Implant pH sensor
(Metronics – Bravo)
Pill-sized camera
(Given Imaging)
MEMS - Microelectromechanical System
Integrated micro devices or systems combining
electrical and mechanical components
Fabricated using integrated circuit (IC) batch
processing techniques
Size range from micrometers to millimetres
Applications includes: accelerometers, pressure,
chemical and flow sensors, micro-optics, optical
scanners, and fluid pumps
Tactile Sensor for Endoscopic Surgery
(SFU)
Pressure sensor for clinical use
(SFU)
CMOS Micromachined Flow Sensor
(SFU)
Power Scavenging
Photovoltaics (Solar cells)
15-20% efficiency (single crystal silicon solar cell)
15mW/cm2
(midday outdoor) to 10µW/cm2
(indoors)
Temperature Gradients
1.6% efficiency (at 5o
C above room temperature)
40 µW/cm2
(5o
C differential, 0.5cm2
, and 1V output)
Human Power
Human body burns 10.5MJ/day (average power dissipation of 121W)
330 µW/cm2
(piezoelectric shoe)
Wind/Air Flow
20-40% efficiency (windmills, with wind velocity 18mph)
Vibrations
Electromagnetic, electrostatic, and piezoelectric devices
200 µW (1cm3
power converter with vibration of 2.25 m/s2
at 120Hz)
Nuclear microbatteries
With 10 milligrams of polonium-210, it can produce 50mW for more than 4 months
It can safely be contained by simple plastic package, as Nickel-63 or tritium can
penetrate no more than 25 mm
Panasonic BP-243318
Applied Digital Solutions –
thermoelectric generator
MIT Media Lab
MIT – MEMS piezoelectric generator
Cornell University - Nuclear micro-
generator (with a processor and a photo sensor)
Power Scavenging
Kinetic energy of vibrating mass to electrical power
Power converted to the electrical system is equal to the power removed from the
mechanical system by be, the electronically induced damping.
m
k
be bm
z(t)
y(t)
Williams and Yates, 1995
ymkzzbbzm me &&&&& −=+++ )(
where z is the spring deflection, y is the input displacement, m is the mass, be is the electrically
induced damping coefficient, bm is the mechanical damping coefficient, and k is the spring constant
2
23
2
42
1
T
e
e
Ym
PzbP
ζ
ωζ
== &
Vibration-to-electricity conversion model
where Y is the Laplace transform of input displacement
acceleration magnitude of input vibration, w is the frequency of the
driving vibrations, is the electrical damping ratio, is the
mechanical damping ratio, and
eζ
meT ζζζ +=
mζ
S.Roundy, P. Wright and J. Rabaey, Energy Scavenging for Wireless Sensor Networks, Kluwer Academic Publishers, 2004.
Human Power Generation
Mitcheson, Yates, Yeatman, Green and Holmes, BSN 2005
Trust,
Security
and Policy
Self-configuration,
healing,
managing of
software components
Network
Storage
and Decision
Support Agents
Multi-sensor
Analysis
and Fusion
Environment
Sensors and
Context
Guang-Zhong Yang, Imperial College, BSN 2005
Wearable pulse oximetry
Zhang et al, watch, R
Imperial e-AR, R
Celka et al, ear cartilage T
Asada et al, ring
finger, R & T
Motorola, R
Mendelson et al, cheek,
forehead, R
Spigulis et al,
trunk & lower limbs, R
Maguire et al, R
Sensor Deployment
Less
Motion
Artifacts
Rich
Subcutaneous
Vascularity
Thin
epidermal
Less
Pigmentation
Easy to wear
PD1
LED1
PD2
LED2
PD3
Guang-Zhong Yang, Lei Wang, BSN 2007
Skin PPG
Non-invasive
technology
Motion
artifact
Optical
shielding
Perfusion
level
Multiple
pick-up sites
Long-term
monitoring
Lightweight
Skin
PPG
Concerns
0 2 4 6 8 10
0
0.2
0.4
0.6
0.8
PPGsignala.c./d.c.(%)
a 10-s Mastroid Process PPG episode
0 2 4 6 8 10
0
0.2
0.4
0.6
0.8
Time (second)
a.c./d.c.(%)
a 10-s Super Temporal PPG episode
Earpiece PPG
Fidelity Index
fHRS = Pspan / Pall
0 50 100 150 200 250 300
0
0.2
0.4
0.6
0.8
1
Relativespectrumdensity
Frequency (BPM)
12 BPM
span
fHRS = 50%
HR = 100BPM
• Verified by multiple subjects at various resting states including sitting,
standing and reading.
• a.c. / d.c. ratio 0.001 - 0.01 and 10% relative signal strength.
Guang-Zhong Yang, Lei Wang, et al BSN 2007
Dynamic Heart Rate
0 2 4 6 8 10 12 14 16 18
40
70
100
130
160
190
HeartRate(BPM)
0 2 4 6 8 10 12 14 16 18
40
70
100
130
160
190
HeartRate(BPM)
0 2 4 6 8 10 12 14 16 18
40
70
100
130
160
190
HeartRate(BPM)
Time (minute)
stand walking @ different speeds
recovery
Subject A
Subject B
Subject C
• Overall 80% sucessful rate
for exercise heart rate
detections.
• For some subjects, heart
rates were detectable even
during maxium exercise load.
• The dynamic heart rates
helped identifying different
exercise stages and retrieving
the recovery period.
Guang-Zhong Yang, Lei Wang, et al BSN 2007
The essence of autonomic computing is to develop self-
management systems and free human from complicated
administration tasks.
The eight characteristics of an autonomic system include:
The Need for Autonomic and
Cognitive Sensing
Self-optimisation
Self-healing
Self-adaptation
Self-scaling
Self-management
Self-configuration
Self-integration
Self-protection
Example probabilistic models for
activity recognition
[Location based Activity Recognition. L.Liao, D. Fox and H. Kautz NIPS ’05
Hierarchical activity models with GPS and
Relational Markov Networks
Recognizing Activities and Spatial Context using Wearable Sensors.
A. Subramanya,A. Raj, J. Bilmes, D.Fox, UAI 06
Dynamic Bayesian Model with data
from wearable sensors and GPS.
Layered Representation for Human Activity Recognition. N. Oliver, E. Horvitz, A. Garg (CVIU 2002)
A Comparison of Dynamic HMM and Dynamic Bayesian Nets for Recognising Office Activities.
N. Oliver and E. Horvitz (UM05)
Layered HMMs with microphone, camera,
mouse and keyboard for office activities
Basic Concepts
Some sensors are more informative with regard
to certain activities than others.
lower limbs sitting, standing, walking
upper limbs typing, hand shaking
Reasoning about different activities requires
different sets of sensors at different locations
and time.
Change in information availability as user
moves through static ambient sensors.
Feature Selection
Feature selection is used for learning the structure of
the proposed distributed model.
To reduce computational complexity while maintaining
accuracy (self-optimising)
To identify features that are relevant to each class.
A2
F5F2 F4
A1
F1 F3
A3
Initial Dependency Graph
Feature Redundancy
Redundancy can be used to improve the reliability and fault
tolerance of the model (self-healing property)
With new objective function, irrelevant features is removed
before redundant features.
( ) ( )b AUC b
EΔ =f f
( )c
Δ f( )AUC c
E f
( )AUC a
E f
( ) ( )d AUC d
EΔ =f f
( ) ( ) ( ) { }( )( ) ( )i i if G f fG ( )
1 1
( )
D 1 k
r AUC AUC
k
AUC E EEω ω= − × − + ×−
a measure of redundancy
Guang-Zhong Yang, Surapa Thiemajarus
Bodynet 2007a
Feature selection for BSN
Experiments were performed on subsets of activities as follows:
Sitting, standing, and walking
Going up and downstairs
Handshaking, writing on white board and typing
Feature selection for sitting, standing and walking:
Average mean and standard
deviation of the classification
accuracy
Model Complexity
The cost of features can be estimated based on:
Number of features
Different levels of communication incurred:
Same sensor node
Different nodes, same subnet
Different subnets
- Sensing Unit
F1
F2
F3
F4
{ }( ) { }( ) { }( )1, 2 1, 3 1, 4Cost F F Cost F F Cost F F< <
An Illustration of Model Construction
A2
F5F2 F4
A1
F1 F3
A3 A2
F5F2 F4
A1
F1 F3
A3A2
F5F2 F4
A1
F1 F3
A3
F5F2 F4F1 F3A2A1 A3
P(A1|F1,F2) P(F2|A2) P(F3|A1,A3) P(A2|F3,F4)
P(F1) P(F4) P(A3)
P(F5|A3)
F5F2 F4F1 F3A2A1 A3
P(A1|F1,F2) P(F2|A2) P(F3|A1) P(A2|F3,F4) P(F3|A3)
P(F1) P(F4) P(A3)
P(F5|A3)
Initialisation
BFFS
Casual
Assignment
Dependency Graph Directed Graph
FG representation
BN to FG
Transformation
Simplified FG representation
Independence
Assumptions
Experiments: Results (con’t)
F1 F16F2
A
F1 F16F2
A1 A2 A11
F14F10F1 F3 F5 F7F4 F6F2 F8 F12F11 F13F9 F16F15
A1 A3 A5 A7A4 A6A2 A8 A10 A11A9
F11F7F5F4F3F2F1 F6 F8 F10 F12 F14F13F9 F16F15
A1 A3 A5 A7A4 A6A2 A8 A10 A11A9
Model 2
Accuracy: 77.3%
#s of Links: 176
#s of Features: 16
Model 3
Accuracy: 66.28%
#s of Links: 34
#s of Features: 13
Model 4
Accuracy: 72.60%
#s of Links: 34
#s of Features: 9
Guang-Zhong Yang, Surapa Thiemajarus Bodynet 2007
Focus of This Talk
Technical Challenges and Opportunities of
BSN
Healthcare and Wellbeing Monitoring
Sports and Entertainment
Conclusions
Drivers of Healthcare Applications
• Aging population
• Chronic disease
• Acute care
• Early diagnosis
Driver 1: The Aging Population
The proportion of elderly people is likely to double from 10% to
20% over the next 50 years.
In the western world, the ratio of workers to retirees is declining.
The number of people living alone is rising.
A change of care provision is needed for these patients.
Driver 2: Chronic Disease
Ischemic heart disease
Hypertension
Diabetes
Neuro-degenerative
disease (Parkinsons,
Alzheimers)
Global deterioration
(Dementias)
Acute presentations
Interventions
Post elective care
Post-operative
monitoring
Driver 3: Acute Disease
Special
Tests
Imaging
Peak
Flow
ECG
Blood
Tests
O2 Sats
Blood
Pressure
Medical
Records
Exam
History
Patient
Only a
SNAPSHOT of a
patient’s health
Driver 4: Diagnostics
BSN for Healthcare
Dynamic
Continuous use 24/7
Preventative
Earlier diagnosis
Home-based
Post-operative monitoring
Unobtrusive
Minimal interventions
Improving Quality-of-Life
Anytime
Anywhere
Anybody
The ageing body
Brain and nervous system
Circulatory system
Musculoskeletal system
Respiratory system
Visual and sensory systems
Implantable Sensors: Microstrain Inc
Array of 12 piezoresistive strain
gauges were embedded within
the implant's tibial component.
Integral miniature coil is used to
harvest energy from an externally
applied alternating field.
A wireless antenna transmits
digital sensor data to a computer
3-D Torque and force data
obtained from implant
Home Monitoring
5 Hours of patient’s day
RunningWalking slowly Lying down Walking fastReading
Activity Labelling
Activity Classification
Guang-Zhong Yang, Omer Aziz, et al, BSN 2006
Gait abnormalities
Propulsive gait Scissors gait Spastic gait Steppage gait Waddling gait
Typical associated diseases
- Carbon monoxide
poisoning
- Manganese poisoning
- Parkinson's disease
- Temporary effects from
drugs
- Stroke
- Cervical spondylosis
with myelopathy
- Liver failure
- Multiple sclerosis
- Pernicious anemia
- Spinal cord trauma
- Cerebral palsy
- Brain abscess
- Brain tumor
- Stroke
- Head trauma
- Multiple sclerosis
- Congenital hip
dysplasia
- Muscular dystrophy
- Spinal muscle
atrophy
- Guillain-Barre syndrome
- Herniated lumbar disk
- Multiple sclerosis
- Peroneal muscle atrophy
- Peroneal nerve trauma
- Poliomyelitis
- Polyneuropathy
- Spinal cord trauma
From Gait to Behaviour Profiling
Guang-Zhong Yang & Benny Lo
Imperial College London
e-AR Sensor
e-AR: How does it works?
Human inner ear
Tiny vestibular organ
3 semicircular canals or hollow
tubes
Each tube detects the 3
different motions: pitch (x), roll
(y) and yaw (z)
Each tube filled with liquid,
and the tube contains millions
of microscopic hairs
z
xy Accelerometer Guang-Zhong Yang & Benny Lo
Imperial College London
Guang-Zhong Yang Imperial College London
FFT of Walking when Recovered
1 51 101 151 201 251 301 351 401 451 501
e-AR for Detecting Changes in Gait Due to Injury
After the initial experiment, one of the
volunteer had an ankle injury
Accelerometer readings of the subject were
recorded before and after the injury, and
when the subject is fully recovered
Distinctive patterns were found when the
subject was suffering from the ankle injury
FFT of Normal Walking
1 51 101 151 201 251 301 351 401 451 501
FFT of Walking with Leg Injury
1 51 101 151 201 251 301 351 401 451 501
Before Injury After Injury Fully Recovered
FFTofaccelerometer
readings
Ankle injury – Cont’d
STSOM – different clusters are
formed for the different gait
patterns (using features from FFT)
KNN – clusters are formed for
different gaits (using features from
wavelet transform), and the
recognition accuracy is above
90%
Normal gait Injured gait
Guang-Zhong Yang & Benny Lo
Imperial College London
Apr 08 IST-034963
Mapping to Elderly Care
Patient moving between different locations - Patient
Discovery
MSN
MSN
MSN
MSN
MSN
ASN
WSH
WSH
WSH
WSH
WSH
WiBro
CDMA 2000
802.11 (WLAN)
802.20 (MBWA)
802.16e
(WiMAX)
HSDPA/HSUPA
LTE-UMTS
BSN
WiBro
CDMA 2000
802.11 (WLAN)
802.20 (MBWA)
802.16e
(WiMAX)
HSDPA/HSUPA
LTE-UMTS
A Question to the Audience ?
A Question to the Audience ?
A Question to the Audience ?
Focus of This Talk
Technical Challenges and Opportunities of
BSN
Healthcare and Wellbeing Monitoring
Sports and Entertainment
Conclusions
Sport Performance Analysis
Applied health science
Wheaton college
Center for Human Performance
San Diego, California
Lab based Analysis
www.sportsci.com
Gait cycle
Initial
contact
Loading
response
Mid
stance
Terminal
stance
Preswing Initial
swing
Mid
swing
Terminal
swing
Initial
contact
Running gait
Stance phase
reversal
Toe off Swing phase
reverse
Initial
contact
Ground reaction force
Force
Time (s)
0 0.1 0.2
C. Vaughan et. al, “Dynamics of Human Gait” (2nd ed), Kiboho Publishers, Cape Town South Africa, 1999
T.F. Novacheck, “The Biomechanics of running”, Gait and Posture 7 (1998) 77-95
Impact peak- the impact
(shock) of the foot to the
ground
Propulsion peak – propulsion of body forward (ie marking
the end of deceleration and the beginning of acceleration)
Sprinting posture
Starting
Stay forward (head down)
Acceleration (10-30m)
foot touches down in front of centre of
gravity
Forward body lean begins to decrease until
normal sprinting position is reached
Maximum speed (30-60m)
Push off angle from ground ~50-55o
Trunk erect with ~5o forward lean
Foot meets ground with ankle slightly
extended directly under centre of gravity
Speed Endurance (60m onwards)
Finishing
Increase stride frequency
http://www.sport-fitness-advisor.com/sprintingtechnique.html
Sprinting
sway
step
forward
Sprinting - Swaying
6.15 7.08 8.01 8.94 9.87 10.80 11.72 12.65 13.58
Time(s)
0.12 0.82 1.52 2.23 2.93 3.63 4.34 5.04
Time(s)
0.65 2.59 4.54 6.48 8.43 10.37 12.32 14.26 16.21 18.15 20.10 22.04 23.99
Time(s)
Rowing with e-AR
Forward/backward
Up/down
Sway
Steady speed Slowing down
Distance running
600m 3000m` 3600m 4200m0m
Sway
Forward/backward
Stride
Guang-Zhong Yang & Benny Lo, Imperial College London
Distance running
0m 600m
Sway
Forward/backward
Stride
Guang-Zhong Yang & Benny Lo, Imperial College London
Safety and Security
Equipment rental
Tracking
Passes & Tickets
Access ControlSocial Interactions
Performance analysis
Safety and security
Passes & Tickets
Social Interactions Access Control
Performance analysis Tracking
Conclusions
The boundary between healthcare and general wellbeing monitoring
is increasingly blurred, body sensor networks provide a unique
platform for the development of pervasive healthcare, well being and
physically engaged gaming
Hardware miniaturisation, ultra-low power design and autonomic
(cognitive) sensing
Pervasive, user centric design is key to different application
scenarios
Heterogenic integration and muti-sensor integration/fusion with
ambient sensing is essential
To Probe Further: http://ww.bsn-web.org
BSN 2008
HongKong
Body sensor networks: challenges & applications

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Body sensor networks: challenges & applications

  • 1. Body Sensor Networks – Research Challenges and Applications Professor Guang-Zhong Yang Institute of Biomedical Engineering Imperial College London http://www.bsn-web.org
  • 2. Acknowledgement Benny Lo Eric Yeatman, Louis Atallah Omer Aziz, Julien Pansiot Surapa Themajarus Lei Wang, Mohammad Elhlew Oliver Wells, Rachel King, Len Fass Ara Darzi
  • 3. Imperial College London: basic stats • 2700 academic and research staff: 6 campuses • 10,000 students (1/3rd post-grad) • 18 Nobel Prize winners • Faculties of Natural Sciences, Engineering, Medicine, and Business School • Highest research income in UK universities: £155 million p.a.; also highest industry funded research in the UK • Total income: £410 million p.a.
  • 4.
  • 5. Evolution of computer technologies Moore's Law 0 1 2 3 4 5 6 7 8 9 1971 1976 1981 1986 1991 1996 2003 Year Transistors(log) Estimate Actual 4004 4-bit 108kHz 0.06MIPS 2.3K transistors 1971 8008 108kHz 8-bit 16kB 0.06MIPS 3.5K transistors 1972 8080 8-bit 2Mhz 0.64MIPS 6k transistors 1974 8086 16-bit 8MHz 0.8MIPS 29K transistors 1978 80286 16-bit 12MHz 2.7MIPS 134K transistors 1982 80386 32-bit 20MHz 6MIPS 275K transistors 1985 80486 25MHz 20MIPS 1.2M transistors 1989 Pentium 32-bit 66MHz 100MIPS 3.2M transistors 1993 Pentium II 233MHz 300MIPS 7.5M transistors 1997 Pentium III 450-500MHz 510MIPS 9.5M transistors 1999 Pentium 4 1.4&1.5GHz 1.7GIPS 42M transistors 2000 Pentium M 600Mhz-1.6GHz 6.5GIPS 77M transistors 2003 P4 Prescott 2.8-3.4 GHz 125M transistors 7GIPS 2004 Pentium D 3.2 GHz 15GIPS 230M transistors 2005 4004 8008 8080 8086 80286 80386 80486 Pentium Pentium II Pentium III Pentium 4 Pentium M P4 Prescott Pentium D http://www.granneman.com/ http://velox.stanford.edu/group/chips_micropro_body.html http://home.datacomm.ch/fmeyer/cpu/ http://www.pc-erfahrung.de/Index.html?ProzessormodelleIntelItanium2.html http://www.pc-erfahrung.de/ http://trillian.randomstuff.org.uk/~stephen/history http://www.theregister.co.uk/2004/02/02/intel_prescott_90nm_pentium/ http://www.intel.com/products/processor/pentiumm/image.htm
  • 6. Evolution of computer technologies Bell’s Law New computing class every decade New applications and contents develop around each new class year log(peoplepercomputer/price)
  • 7. WSN – dust 11.7mm3 Solar powered Bi-directional communications (laser light house) Sensing (acceleration and ambient light)
  • 8. Habitat Monitoring: Great Duck Island Study In the spring 2002 and in August 2003, Intel Research Lab Berkeley deployed a large number of wireless sensor network nodes on Great Duck Island which monitors the microclimates in and around nesting burrows used by the Leach’s Storm Petrel. Aimed to develop a habitat monitoring kit for non-intrusive and non-disruptive monitoring of sensitive wildlife and habitats. Each mote has a microcontroller, a low-power radio, memory and batteries. Temperature, humidity, barometric pressure, and mid-range infrared sensors were used. Motes periodically sample and relay their sensor readings to computer base stations on the island. These in turn feed into a satellite link that allows researchers to access real-time environmental data over the Internet.
  • 9. Location tracking: MIT - Cricket Cricket is indoor location system for pervasive and sensor-based computing environments Ultrasound sensors are integrated with motes for tracking objects and activities Provides location information – identify space, position, coordinates and orientation of the subject – to applications running on handhelds, laptops, and sensor nodes Intended for indoor usage where outdoor systems like GPS wouldn’t work
  • 10. Structural Health Monitoring: Golden gate bridge study Golden gate bridge is exposed to strong wind and earth quake Budget for structural monitoring ~US$1,000,000 Accelerometers are used to monitoring the vibration on the bridge and temperature sensors are integrated to calibrate the accelerometer against temperature difference
  • 12. Wireless and Body Sensor Networks Cover the human body Fewer sensor nodes Single multitasking sensors Robust & Accurate Miniaturization Pervasive Predictable environment Motion artefacts an issue Early adverse event detection Failure irreversible Variable structure Cover the environment Large number of nodes Multiple dedicated sensors Lower accuracy Small size not limiting factor Resistant to weather, Resistant to noise Resistant to asynchrony Early adverse event detection Failure reversible Fixed structure WSN BSN
  • 13. Wireless and Body Sensor Networks Low level security Accessible power supply High power demand Solar,wind power Replaceable/disposable No biocompatibility needed Low context awareness Wireless solutions available Data loss less of an issue High security Inaccessible power source Lower power availability Thermal, piezoelectric energy Biodegradeable Biocompatible High context awareness Lower power wireless Sensitive to data loss WSN BSN
  • 14. Focus of This Talk Technical Challenges and Opportunities of BSN Healthcare and Wellbeing Monitoring Sports and Entertainment Conclusions
  • 15. Focus of This Talk Technical Challenges and Opportunities of BSN Healthcare and Wellbeing Monitoring Sports and Entertainment Conclusions
  • 16. Biosensor Design Biocompatibility & Materials Wireless Communication Low Power Design & Scavenging Autonomic Sensing Standards & Integration BSN WhatdoesBSNCover?
  • 17. Biocompatibility and Materials Biosensors Stents Tissue Engineering Pattern and manipulate cells in micro-array format Drug delivery systems Carol Ezzell Webb, “Chip Shots”, IEEE Spectrum Oct 2004 Smart Pill – Sun-Sentinel Co. Implant blood pressure flow sensor (CardioMEMS) Drug releasing stents - Taxus stents - Boston Scientific Co. Ozkan et. al (2003), Langmuir
  • 18. Biosensor Design Thermistor ECG SpO2 Glucose concentration Implant blood pressure flow sensor (CardioMEMS) Glucose sensor (Glucowatch) Thermistor (ACR system) Implant ECG recorder (Medtronics –Reveal) Oxymeter (Advanced Micronics) Implant pH sensor (Metronics – Bravo) Pill-sized camera (Given Imaging)
  • 19. MEMS - Microelectromechanical System Integrated micro devices or systems combining electrical and mechanical components Fabricated using integrated circuit (IC) batch processing techniques Size range from micrometers to millimetres Applications includes: accelerometers, pressure, chemical and flow sensors, micro-optics, optical scanners, and fluid pumps Tactile Sensor for Endoscopic Surgery (SFU) Pressure sensor for clinical use (SFU) CMOS Micromachined Flow Sensor (SFU)
  • 20. Power Scavenging Photovoltaics (Solar cells) 15-20% efficiency (single crystal silicon solar cell) 15mW/cm2 (midday outdoor) to 10µW/cm2 (indoors) Temperature Gradients 1.6% efficiency (at 5o C above room temperature) 40 µW/cm2 (5o C differential, 0.5cm2 , and 1V output) Human Power Human body burns 10.5MJ/day (average power dissipation of 121W) 330 µW/cm2 (piezoelectric shoe) Wind/Air Flow 20-40% efficiency (windmills, with wind velocity 18mph) Vibrations Electromagnetic, electrostatic, and piezoelectric devices 200 µW (1cm3 power converter with vibration of 2.25 m/s2 at 120Hz) Nuclear microbatteries With 10 milligrams of polonium-210, it can produce 50mW for more than 4 months It can safely be contained by simple plastic package, as Nickel-63 or tritium can penetrate no more than 25 mm Panasonic BP-243318 Applied Digital Solutions – thermoelectric generator MIT Media Lab MIT – MEMS piezoelectric generator Cornell University - Nuclear micro- generator (with a processor and a photo sensor)
  • 21. Power Scavenging Kinetic energy of vibrating mass to electrical power Power converted to the electrical system is equal to the power removed from the mechanical system by be, the electronically induced damping. m k be bm z(t) y(t) Williams and Yates, 1995 ymkzzbbzm me &&&&& −=+++ )( where z is the spring deflection, y is the input displacement, m is the mass, be is the electrically induced damping coefficient, bm is the mechanical damping coefficient, and k is the spring constant 2 23 2 42 1 T e e Ym PzbP ζ ωζ == & Vibration-to-electricity conversion model where Y is the Laplace transform of input displacement acceleration magnitude of input vibration, w is the frequency of the driving vibrations, is the electrical damping ratio, is the mechanical damping ratio, and eζ meT ζζζ += mζ S.Roundy, P. Wright and J. Rabaey, Energy Scavenging for Wireless Sensor Networks, Kluwer Academic Publishers, 2004.
  • 22. Human Power Generation Mitcheson, Yates, Yeatman, Green and Holmes, BSN 2005
  • 23. Trust, Security and Policy Self-configuration, healing, managing of software components Network Storage and Decision Support Agents Multi-sensor Analysis and Fusion Environment Sensors and Context Guang-Zhong Yang, Imperial College, BSN 2005
  • 24. Wearable pulse oximetry Zhang et al, watch, R Imperial e-AR, R Celka et al, ear cartilage T Asada et al, ring finger, R & T Motorola, R Mendelson et al, cheek, forehead, R Spigulis et al, trunk & lower limbs, R Maguire et al, R
  • 27. 0 2 4 6 8 10 0 0.2 0.4 0.6 0.8 PPGsignala.c./d.c.(%) a 10-s Mastroid Process PPG episode 0 2 4 6 8 10 0 0.2 0.4 0.6 0.8 Time (second) a.c./d.c.(%) a 10-s Super Temporal PPG episode Earpiece PPG Fidelity Index fHRS = Pspan / Pall 0 50 100 150 200 250 300 0 0.2 0.4 0.6 0.8 1 Relativespectrumdensity Frequency (BPM) 12 BPM span fHRS = 50% HR = 100BPM • Verified by multiple subjects at various resting states including sitting, standing and reading. • a.c. / d.c. ratio 0.001 - 0.01 and 10% relative signal strength. Guang-Zhong Yang, Lei Wang, et al BSN 2007
  • 28. Dynamic Heart Rate 0 2 4 6 8 10 12 14 16 18 40 70 100 130 160 190 HeartRate(BPM) 0 2 4 6 8 10 12 14 16 18 40 70 100 130 160 190 HeartRate(BPM) 0 2 4 6 8 10 12 14 16 18 40 70 100 130 160 190 HeartRate(BPM) Time (minute) stand walking @ different speeds recovery Subject A Subject B Subject C • Overall 80% sucessful rate for exercise heart rate detections. • For some subjects, heart rates were detectable even during maxium exercise load. • The dynamic heart rates helped identifying different exercise stages and retrieving the recovery period. Guang-Zhong Yang, Lei Wang, et al BSN 2007
  • 29. The essence of autonomic computing is to develop self- management systems and free human from complicated administration tasks. The eight characteristics of an autonomic system include: The Need for Autonomic and Cognitive Sensing Self-optimisation Self-healing Self-adaptation Self-scaling Self-management Self-configuration Self-integration Self-protection
  • 30. Example probabilistic models for activity recognition [Location based Activity Recognition. L.Liao, D. Fox and H. Kautz NIPS ’05 Hierarchical activity models with GPS and Relational Markov Networks Recognizing Activities and Spatial Context using Wearable Sensors. A. Subramanya,A. Raj, J. Bilmes, D.Fox, UAI 06 Dynamic Bayesian Model with data from wearable sensors and GPS. Layered Representation for Human Activity Recognition. N. Oliver, E. Horvitz, A. Garg (CVIU 2002) A Comparison of Dynamic HMM and Dynamic Bayesian Nets for Recognising Office Activities. N. Oliver and E. Horvitz (UM05) Layered HMMs with microphone, camera, mouse and keyboard for office activities
  • 31. Basic Concepts Some sensors are more informative with regard to certain activities than others. lower limbs sitting, standing, walking upper limbs typing, hand shaking Reasoning about different activities requires different sets of sensors at different locations and time. Change in information availability as user moves through static ambient sensors.
  • 32. Feature Selection Feature selection is used for learning the structure of the proposed distributed model. To reduce computational complexity while maintaining accuracy (self-optimising) To identify features that are relevant to each class. A2 F5F2 F4 A1 F1 F3 A3 Initial Dependency Graph
  • 33. Feature Redundancy Redundancy can be used to improve the reliability and fault tolerance of the model (self-healing property) With new objective function, irrelevant features is removed before redundant features. ( ) ( )b AUC b EΔ =f f ( )c Δ f( )AUC c E f ( )AUC a E f ( ) ( )d AUC d EΔ =f f ( ) ( ) ( ) { }( )( ) ( )i i if G f fG ( ) 1 1 ( ) D 1 k r AUC AUC k AUC E EEω ω= − × − + ×− a measure of redundancy Guang-Zhong Yang, Surapa Thiemajarus Bodynet 2007a
  • 34. Feature selection for BSN Experiments were performed on subsets of activities as follows: Sitting, standing, and walking Going up and downstairs Handshaking, writing on white board and typing Feature selection for sitting, standing and walking: Average mean and standard deviation of the classification accuracy
  • 35. Model Complexity The cost of features can be estimated based on: Number of features Different levels of communication incurred: Same sensor node Different nodes, same subnet Different subnets - Sensing Unit F1 F2 F3 F4 { }( ) { }( ) { }( )1, 2 1, 3 1, 4Cost F F Cost F F Cost F F< <
  • 36. An Illustration of Model Construction A2 F5F2 F4 A1 F1 F3 A3 A2 F5F2 F4 A1 F1 F3 A3A2 F5F2 F4 A1 F1 F3 A3 F5F2 F4F1 F3A2A1 A3 P(A1|F1,F2) P(F2|A2) P(F3|A1,A3) P(A2|F3,F4) P(F1) P(F4) P(A3) P(F5|A3) F5F2 F4F1 F3A2A1 A3 P(A1|F1,F2) P(F2|A2) P(F3|A1) P(A2|F3,F4) P(F3|A3) P(F1) P(F4) P(A3) P(F5|A3) Initialisation BFFS Casual Assignment Dependency Graph Directed Graph FG representation BN to FG Transformation Simplified FG representation Independence Assumptions
  • 37. Experiments: Results (con’t) F1 F16F2 A F1 F16F2 A1 A2 A11 F14F10F1 F3 F5 F7F4 F6F2 F8 F12F11 F13F9 F16F15 A1 A3 A5 A7A4 A6A2 A8 A10 A11A9 F11F7F5F4F3F2F1 F6 F8 F10 F12 F14F13F9 F16F15 A1 A3 A5 A7A4 A6A2 A8 A10 A11A9 Model 2 Accuracy: 77.3% #s of Links: 176 #s of Features: 16 Model 3 Accuracy: 66.28% #s of Links: 34 #s of Features: 13 Model 4 Accuracy: 72.60% #s of Links: 34 #s of Features: 9 Guang-Zhong Yang, Surapa Thiemajarus Bodynet 2007
  • 38. Focus of This Talk Technical Challenges and Opportunities of BSN Healthcare and Wellbeing Monitoring Sports and Entertainment Conclusions
  • 39. Drivers of Healthcare Applications • Aging population • Chronic disease • Acute care • Early diagnosis
  • 40. Driver 1: The Aging Population The proportion of elderly people is likely to double from 10% to 20% over the next 50 years. In the western world, the ratio of workers to retirees is declining. The number of people living alone is rising. A change of care provision is needed for these patients.
  • 41. Driver 2: Chronic Disease Ischemic heart disease Hypertension Diabetes Neuro-degenerative disease (Parkinsons, Alzheimers) Global deterioration (Dementias)
  • 42. Acute presentations Interventions Post elective care Post-operative monitoring Driver 3: Acute Disease
  • 44. BSN for Healthcare Dynamic Continuous use 24/7 Preventative Earlier diagnosis Home-based Post-operative monitoring Unobtrusive Minimal interventions Improving Quality-of-Life Anytime Anywhere Anybody
  • 45. The ageing body Brain and nervous system Circulatory system Musculoskeletal system Respiratory system Visual and sensory systems
  • 46. Implantable Sensors: Microstrain Inc Array of 12 piezoresistive strain gauges were embedded within the implant's tibial component. Integral miniature coil is used to harvest energy from an externally applied alternating field. A wireless antenna transmits digital sensor data to a computer 3-D Torque and force data obtained from implant
  • 48. 5 Hours of patient’s day
  • 49. RunningWalking slowly Lying down Walking fastReading Activity Labelling
  • 50. Activity Classification Guang-Zhong Yang, Omer Aziz, et al, BSN 2006
  • 51. Gait abnormalities Propulsive gait Scissors gait Spastic gait Steppage gait Waddling gait Typical associated diseases - Carbon monoxide poisoning - Manganese poisoning - Parkinson's disease - Temporary effects from drugs - Stroke - Cervical spondylosis with myelopathy - Liver failure - Multiple sclerosis - Pernicious anemia - Spinal cord trauma - Cerebral palsy - Brain abscess - Brain tumor - Stroke - Head trauma - Multiple sclerosis - Congenital hip dysplasia - Muscular dystrophy - Spinal muscle atrophy - Guillain-Barre syndrome - Herniated lumbar disk - Multiple sclerosis - Peroneal muscle atrophy - Peroneal nerve trauma - Poliomyelitis - Polyneuropathy - Spinal cord trauma From Gait to Behaviour Profiling
  • 52. Guang-Zhong Yang & Benny Lo Imperial College London
  • 53. e-AR Sensor e-AR: How does it works? Human inner ear Tiny vestibular organ 3 semicircular canals or hollow tubes Each tube detects the 3 different motions: pitch (x), roll (y) and yaw (z) Each tube filled with liquid, and the tube contains millions of microscopic hairs z xy Accelerometer Guang-Zhong Yang & Benny Lo Imperial College London
  • 54. Guang-Zhong Yang Imperial College London
  • 55. FFT of Walking when Recovered 1 51 101 151 201 251 301 351 401 451 501 e-AR for Detecting Changes in Gait Due to Injury After the initial experiment, one of the volunteer had an ankle injury Accelerometer readings of the subject were recorded before and after the injury, and when the subject is fully recovered Distinctive patterns were found when the subject was suffering from the ankle injury FFT of Normal Walking 1 51 101 151 201 251 301 351 401 451 501 FFT of Walking with Leg Injury 1 51 101 151 201 251 301 351 401 451 501 Before Injury After Injury Fully Recovered FFTofaccelerometer readings
  • 56. Ankle injury – Cont’d STSOM – different clusters are formed for the different gait patterns (using features from FFT) KNN – clusters are formed for different gaits (using features from wavelet transform), and the recognition accuracy is above 90% Normal gait Injured gait Guang-Zhong Yang & Benny Lo Imperial College London
  • 57. Apr 08 IST-034963 Mapping to Elderly Care Patient moving between different locations - Patient Discovery MSN MSN MSN MSN MSN ASN WSH WSH WSH WSH WSH WiBro CDMA 2000 802.11 (WLAN) 802.20 (MBWA) 802.16e (WiMAX) HSDPA/HSUPA LTE-UMTS BSN WiBro CDMA 2000 802.11 (WLAN) 802.20 (MBWA) 802.16e (WiMAX) HSDPA/HSUPA LTE-UMTS
  • 58. A Question to the Audience ?
  • 59. A Question to the Audience ?
  • 60. A Question to the Audience ?
  • 61. Focus of This Talk Technical Challenges and Opportunities of BSN Healthcare and Wellbeing Monitoring Sports and Entertainment Conclusions
  • 62. Sport Performance Analysis Applied health science Wheaton college Center for Human Performance San Diego, California
  • 65. Initial contact Running gait Stance phase reversal Toe off Swing phase reverse Initial contact
  • 66. Ground reaction force Force Time (s) 0 0.1 0.2 C. Vaughan et. al, “Dynamics of Human Gait” (2nd ed), Kiboho Publishers, Cape Town South Africa, 1999 T.F. Novacheck, “The Biomechanics of running”, Gait and Posture 7 (1998) 77-95 Impact peak- the impact (shock) of the foot to the ground Propulsion peak – propulsion of body forward (ie marking the end of deceleration and the beginning of acceleration)
  • 67. Sprinting posture Starting Stay forward (head down) Acceleration (10-30m) foot touches down in front of centre of gravity Forward body lean begins to decrease until normal sprinting position is reached Maximum speed (30-60m) Push off angle from ground ~50-55o Trunk erect with ~5o forward lean Foot meets ground with ankle slightly extended directly under centre of gravity Speed Endurance (60m onwards) Finishing Increase stride frequency http://www.sport-fitness-advisor.com/sprintingtechnique.html
  • 69. Sprinting - Swaying 6.15 7.08 8.01 8.94 9.87 10.80 11.72 12.65 13.58 Time(s) 0.12 0.82 1.52 2.23 2.93 3.63 4.34 5.04 Time(s) 0.65 2.59 4.54 6.48 8.43 10.37 12.32 14.26 16.21 18.15 20.10 22.04 23.99 Time(s)
  • 71. Distance running 600m 3000m` 3600m 4200m0m Sway Forward/backward Stride Guang-Zhong Yang & Benny Lo, Imperial College London
  • 72. Distance running 0m 600m Sway Forward/backward Stride Guang-Zhong Yang & Benny Lo, Imperial College London
  • 73.
  • 74. Safety and Security Equipment rental Tracking Passes & Tickets Access ControlSocial Interactions Performance analysis
  • 75. Safety and security Passes & Tickets Social Interactions Access Control Performance analysis Tracking
  • 76. Conclusions The boundary between healthcare and general wellbeing monitoring is increasingly blurred, body sensor networks provide a unique platform for the development of pervasive healthcare, well being and physically engaged gaming Hardware miniaturisation, ultra-low power design and autonomic (cognitive) sensing Pervasive, user centric design is key to different application scenarios Heterogenic integration and muti-sensor integration/fusion with ambient sensing is essential
  • 77. To Probe Further: http://ww.bsn-web.org BSN 2008 HongKong