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Dylan Hughes
    Bio 101
What is Opium
•   A highly addictive
    drug refined from
    opium poppies.

•   Also from the Poppy
    we can refine
    Morphine, Codeine,
    thebaine, and
    Papverine.

•   Opium can be made
    into Heroin which is
    even more potent
    than normal opium
MEDICAL
NARCOTIC

   Heroin (Diamorphine) is a       Morphine is refined from
    highly addictive drug that       opium and is used in
                                     medicine as a pain killer for
    can be fatal in the wrong        moderate to severe pain
    dosage                          Codeine is another pain
   HIV, Hepatitis can be            killer found form opium.
    spread by addicts sharing        Which is used to more
                                     chronic pains issues.
    needles to inject.
                                    Thebaine in opium can now
   A multimillion dollar            be tested to determine if a
    industry is based around         person is using medical
    growing heroin and               products with morphine or
                                     using illegal substances like
    selling it.                      heroin.
First time users will feel:
• A euphoric feelings – Heroin increases Dopamine activity in the brain

• After the Heroin has worn the good feeling goes with it.

• People quickly want that feeling back which is why Heroin is so addictive.

• In Some European Countries (United Kingdom, Germany, Denmark, Netherlands)
  it is a LEGAL medicine that can be prescribed.

•   Heroin is a great drug at blocking pain receptors in the brain and can be used to help
    treat chronic pain and even provide comfort to terminal cancer patients.

• Heroin can be snorted, injected, smoked, and some people have even made opium tea
That is said to have similar but less potent effects.
Heroin upon injection goes to the blood brain barrier and goes right past
It because Heroin is fat soluble.

It then binds to the opiate receptors in our brains.

Heroin Also causes Analgesic (pain relief) and Anxiolytic ( Anti- Anxiety) for
Some people.

The drug is so addictive it quickly unbalances a persons brain chemistry creating a
Biological dependence on the drug that is extremely difficult to beat without
Medical support.
Long term use does have its risks:
• The biggest risk is a fatal Overdose
• Users can also contract HIV/AIDS from sharing needles

• Heart attack, collapsed veins, Pneumonia, Sores on the body, and
 slowly the liver begins to fail.


• A person can also get infections from any number of other chemicals
• That are used in the process of making (cutting) the Heroin for sale.

• The different types of heroin can all carry with them their own side effects.
• Treatment for Heroin comes in several forms :

• Detox (Cold Turkey) is the hardest form of treatment. A person literally
goes through a nightmare of physical and psychological symptoms.

• High fevers and chills, vomiting, cramps, uncontrollable shaking, loss of
 appetite. Headaches and extreme pain all over a persons body.

• Some people will receive a opiate blocker especially in cases of a serve
  overdose of heroin. This will cure a person overnight but if they relapse
  there is a higher risk over a fatal overdose.
         This happens because a persons body no longer processes the
         heroin correctly
A Methadone regimen is used to slowly take a person of
Heroin in small amounts .

A great deal of people find help from N.A. meetings or from individual therapy
sessions to help them deal with cravings and make life style changes to help
them with their remissions.
   Used as early as 3400
    B.C.
   Ancient Egyptians
    used it and sold it on
    trade routes.
   Banned during the
    Inquisition and
    reintroduced in the
    1500’s
   First Opium war in
    1840 fought over
    China ordering the
    end of foreign sale
   Opium is fist injected
    in the mid 1800’s
   1856 – 2nd opium war
    in china
   1874- Heroin is
    synthesized
   In 1923 Opium is banned in the United states

   Huge rise in Heroin use after Vietnam

   1970’s- Mexican Opium trade is destroyed.

   The middle east assumes control of opium
    productions in the 1990’s
Most of the
Opium today is
Middle East
mainly in
Afghanistan
before the war
began and most
of the crops
 were burned by
U.S. forces. But as
of 2002 it is still
the Largest
Opium maker in
the world.
The Modern war on drugs has largely been unsuccessful in stopping
The illegal importation of narcotics into the continental United States.




     More people are becoming addicted every years and stronger variations
     Of Heroin are flooding the streets everyday.
   The sale of
    illegal drugs is
    a huge business
    making billions
    of dollars per
    year off of
    addictions who
    cannot quit.


                       $205.6 million dollars seized in drug raid in Mexico
Farming Opium
Farming of Opium has ranged from
China to Mexico and back.

Vietnam, Burma, Laos, China, India
, Mexico, and the United Kingdom
are just some of the countries who
has been involved in growing
Poppies.

It is truly a Global Issue and more
and more farmers and crop shares
are turning to growing poppy to
make quick money to support
themselves and their families.
• Opium today is huge issue

• Addiction rates are on the rise

• History has shown just how violent people will get over Opium

• There is a lot of money and politics involved

• Money from the sale of Heroin and other opiates help finance Terrorism in
 in the middle east.
    Laçine Aksoy, Opium poppy (Papaver
    somniferum L.) oil for preparation of biodiesel:      P. Prioreschi, R.P. Heaney, E. Brehm, A quantitative
                                                           assessment of ancient therapeutics: poppy and pain
    Optimization of conditions, Applied Energy,            in the Hippocratic corpus, Medical Hypotheses,
    Volume 88, Issue 12, December 2011, Pages 4713-        Volume 51, Issue 4, October 1998, Pages 325-331,
    4718, ISSN 0306-2619,                                  ISSN 0306-9877, 10.1016/S0306-9877(98)90057-3.
                                                          (http://www.sciencedirect.com/science/article/pii/
    10.1016/j.apenergy.2011.06.012.                        S0306987798900573)
    (http://www.sciencedirect.com/science/article
    /pii/S0306261911003825)
   Peter J. Facchini, Sang-Un Park, Developmental        Sooyeun Lee, Yonghoon Park, Eunyoung Han,
                                                           Hwakyung Choi, Heesun Chung, Seung Min Oh,
    and inducible accumulation of gene transcripts         Kyu Hyuck Chung, Thebaine in hair as a marker for
    involved in alkaloid biosynthesis in opium             chronic use of illegal opium poppy substances,
    poppy, Phytochemistry, Volume 64, Issue 1,             Forensic Science International, Volume 204, Issues 1-
                                                           3, 30 January 2011, Pages 115-118, ISSN 0379-0738,
    September 2003, Pages 177-186, ISSN 0031-9422,         10.1016/j.forsciint.2010.05.013.
    10.1016/S0031-9422(03)00292-                          (http://www.sciencedirect.com/science/article/pii/
    9.(http://www.sciencedirect.com/science/articl         S0379073810002677)
    e/pii/S0031942203002929)
   Jörg Ziegler, Peter J. Facchini, René Geißler,
                                                          A. Yoshida, H. Chanhda, Yan-Mei Ye, Yue-Rong
    Jürgen Schmidt, Christian Ammer, Robert                Liang, Ecosystem service values and land use change
    Kramell, Susan Voigtländer, Andreas Gesell,            in the opium poppy cultivation region in Northern
    Silke Pienkny, Wolfgang Brandt, Evolution of           Part of Lao PDR, Acta Ecologica Sinica, Volume 30,
                                                           Issue 2, April 2010, Pages 56-61, ISSN 1872-2032,
    morphine biosynthesis in opium poppy,                  10.1016/j.chnaes.2010.03.002.
    Phytochemistry, Volume 70, Issues 15-16,              (http://www.sciencedirect.com/science/article/pii/
    October-November 2009, Pages 1696-1707, ISSN           S1872203210000065)
    0031-9422,
    10.1016/j.phytochem.2009.07.006.(http://www.s
    ciencedirect.com/science/article/pii/S00319422
    09002817)
Graham Farrell, John Thorne, Where have all the flowers gone?: evaluation of the Taliban crackdown
against opium poppy cultivation in Afghanistan, International Journal of Drug Policy, Volume 16, Issue
2, March 2005, Pages 81-91, ISSN 0955-
3959, 10.1016/j.drugpo.2004.07.007.(http://www.sciencedirect.com/science/article/pii/S095539590400094
5)


Peter J. Facchini, Sang-Un Park, Developmental and inducible accumulation of gene transcripts involved in
alkaloid biosynthesis in opium poppy, Phytochemistry, Volume 64, Issue 1, September 2003, Pages 177-
186, ISSN 0031-9422, 10.1016/S0031-9422(03)00292-9.
(http://www.sciencedirect.com/science/article/pii/S0031942203002929)


Peter J. Facchini, Sang-Un Park, Developmental and inducible accumulation of gene transcripts involved in
alkaloid biosynthesis in opium poppy, Phytochemistry, Volume 64, Issue 1, September 2003, Pages 177-
186, ISSN 0031-9422, 10.1016/S0031-9422(03)00292-9.
(http://www.sciencedirect.com/science/article/pii/S0031942203002929)

http://opioids.com/timeline/ - Opium: A history, By martin Booth, 1996, Simon & Schuster, Ltd

http://www.drugs.com/opium.html - Used for some general information about Opium and Heroin.
http://www.flickr.com/photos/cod_gabriel/2223556912/sizes/l/in/photostream/
- Cod_gabriel – dec 24, 2007

http://www.flickr.com/photos/jamesscottbrown/522074884/ - James scott Brown –
May 30th 2007

http://www.flickr.com/photos/vculibraries/6032628788/sizes/l/in/photostream/
- VCU Libraries August 11,2011

http://www.flickr.com/photos/planspark/4415256988/ -
Planspark – march 7, 2010

http://www.flickr.com/photos/31256440@N07/5618788689/ - Nsikander28 – April
14, 2011

http://www.flickr.com/photos/wdwbarber/534617732/
Bill barker April 27th 2007

http://www.flickr.com/photos/theklan/2316132157/
Mr. Theklan – March 7th, 2008

http://www.flickr.com/photos/theklan/2316132157/
Mr. Theklan – March 7th, 2008

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History and Effects of Opium

  • 1. Dylan Hughes Bio 101
  • 2. What is Opium • A highly addictive drug refined from opium poppies. • Also from the Poppy we can refine Morphine, Codeine, thebaine, and Papverine. • Opium can be made into Heroin which is even more potent than normal opium
  • 3. MEDICAL NARCOTIC  Heroin (Diamorphine) is a  Morphine is refined from highly addictive drug that opium and is used in medicine as a pain killer for can be fatal in the wrong moderate to severe pain dosage  Codeine is another pain  HIV, Hepatitis can be killer found form opium. spread by addicts sharing Which is used to more chronic pains issues. needles to inject.  Thebaine in opium can now  A multimillion dollar be tested to determine if a industry is based around person is using medical growing heroin and products with morphine or using illegal substances like selling it. heroin.
  • 4. First time users will feel: • A euphoric feelings – Heroin increases Dopamine activity in the brain • After the Heroin has worn the good feeling goes with it. • People quickly want that feeling back which is why Heroin is so addictive. • In Some European Countries (United Kingdom, Germany, Denmark, Netherlands) it is a LEGAL medicine that can be prescribed. • Heroin is a great drug at blocking pain receptors in the brain and can be used to help treat chronic pain and even provide comfort to terminal cancer patients. • Heroin can be snorted, injected, smoked, and some people have even made opium tea That is said to have similar but less potent effects.
  • 5. Heroin upon injection goes to the blood brain barrier and goes right past It because Heroin is fat soluble. It then binds to the opiate receptors in our brains. Heroin Also causes Analgesic (pain relief) and Anxiolytic ( Anti- Anxiety) for Some people. The drug is so addictive it quickly unbalances a persons brain chemistry creating a Biological dependence on the drug that is extremely difficult to beat without Medical support.
  • 6. Long term use does have its risks: • The biggest risk is a fatal Overdose • Users can also contract HIV/AIDS from sharing needles • Heart attack, collapsed veins, Pneumonia, Sores on the body, and slowly the liver begins to fail. • A person can also get infections from any number of other chemicals • That are used in the process of making (cutting) the Heroin for sale. • The different types of heroin can all carry with them their own side effects.
  • 7. • Treatment for Heroin comes in several forms : • Detox (Cold Turkey) is the hardest form of treatment. A person literally goes through a nightmare of physical and psychological symptoms. • High fevers and chills, vomiting, cramps, uncontrollable shaking, loss of appetite. Headaches and extreme pain all over a persons body. • Some people will receive a opiate blocker especially in cases of a serve overdose of heroin. This will cure a person overnight but if they relapse there is a higher risk over a fatal overdose. This happens because a persons body no longer processes the heroin correctly
  • 8. A Methadone regimen is used to slowly take a person of Heroin in small amounts . A great deal of people find help from N.A. meetings or from individual therapy sessions to help them deal with cravings and make life style changes to help them with their remissions.
  • 9. Used as early as 3400 B.C.  Ancient Egyptians used it and sold it on trade routes.  Banned during the Inquisition and reintroduced in the 1500’s
  • 10. First Opium war in 1840 fought over China ordering the end of foreign sale  Opium is fist injected in the mid 1800’s  1856 – 2nd opium war in china  1874- Heroin is synthesized
  • 11. In 1923 Opium is banned in the United states  Huge rise in Heroin use after Vietnam  1970’s- Mexican Opium trade is destroyed.  The middle east assumes control of opium productions in the 1990’s
  • 12. Most of the Opium today is Middle East mainly in Afghanistan before the war began and most of the crops were burned by U.S. forces. But as of 2002 it is still the Largest Opium maker in the world.
  • 13. The Modern war on drugs has largely been unsuccessful in stopping The illegal importation of narcotics into the continental United States. More people are becoming addicted every years and stronger variations Of Heroin are flooding the streets everyday.
  • 14. The sale of illegal drugs is a huge business making billions of dollars per year off of addictions who cannot quit. $205.6 million dollars seized in drug raid in Mexico
  • 15. Farming Opium Farming of Opium has ranged from China to Mexico and back. Vietnam, Burma, Laos, China, India , Mexico, and the United Kingdom are just some of the countries who has been involved in growing Poppies. It is truly a Global Issue and more and more farmers and crop shares are turning to growing poppy to make quick money to support themselves and their families.
  • 16. • Opium today is huge issue • Addiction rates are on the rise • History has shown just how violent people will get over Opium • There is a lot of money and politics involved • Money from the sale of Heroin and other opiates help finance Terrorism in in the middle east.
  • 17. Laçine Aksoy, Opium poppy (Papaver somniferum L.) oil for preparation of biodiesel:  P. Prioreschi, R.P. Heaney, E. Brehm, A quantitative assessment of ancient therapeutics: poppy and pain Optimization of conditions, Applied Energy, in the Hippocratic corpus, Medical Hypotheses, Volume 88, Issue 12, December 2011, Pages 4713- Volume 51, Issue 4, October 1998, Pages 325-331, 4718, ISSN 0306-2619, ISSN 0306-9877, 10.1016/S0306-9877(98)90057-3.  (http://www.sciencedirect.com/science/article/pii/ 10.1016/j.apenergy.2011.06.012. S0306987798900573) (http://www.sciencedirect.com/science/article /pii/S0306261911003825)  Peter J. Facchini, Sang-Un Park, Developmental  Sooyeun Lee, Yonghoon Park, Eunyoung Han, Hwakyung Choi, Heesun Chung, Seung Min Oh, and inducible accumulation of gene transcripts Kyu Hyuck Chung, Thebaine in hair as a marker for involved in alkaloid biosynthesis in opium chronic use of illegal opium poppy substances, poppy, Phytochemistry, Volume 64, Issue 1, Forensic Science International, Volume 204, Issues 1- 3, 30 January 2011, Pages 115-118, ISSN 0379-0738, September 2003, Pages 177-186, ISSN 0031-9422, 10.1016/j.forsciint.2010.05.013. 10.1016/S0031-9422(03)00292-  (http://www.sciencedirect.com/science/article/pii/ 9.(http://www.sciencedirect.com/science/articl S0379073810002677) e/pii/S0031942203002929)  Jörg Ziegler, Peter J. Facchini, René Geißler,  A. Yoshida, H. Chanhda, Yan-Mei Ye, Yue-Rong Jürgen Schmidt, Christian Ammer, Robert Liang, Ecosystem service values and land use change Kramell, Susan Voigtländer, Andreas Gesell, in the opium poppy cultivation region in Northern Silke Pienkny, Wolfgang Brandt, Evolution of Part of Lao PDR, Acta Ecologica Sinica, Volume 30, Issue 2, April 2010, Pages 56-61, ISSN 1872-2032, morphine biosynthesis in opium poppy, 10.1016/j.chnaes.2010.03.002. Phytochemistry, Volume 70, Issues 15-16,  (http://www.sciencedirect.com/science/article/pii/ October-November 2009, Pages 1696-1707, ISSN S1872203210000065) 0031-9422, 10.1016/j.phytochem.2009.07.006.(http://www.s ciencedirect.com/science/article/pii/S00319422 09002817)
  • 18. Graham Farrell, John Thorne, Where have all the flowers gone?: evaluation of the Taliban crackdown against opium poppy cultivation in Afghanistan, International Journal of Drug Policy, Volume 16, Issue 2, March 2005, Pages 81-91, ISSN 0955- 3959, 10.1016/j.drugpo.2004.07.007.(http://www.sciencedirect.com/science/article/pii/S095539590400094 5) Peter J. Facchini, Sang-Un Park, Developmental and inducible accumulation of gene transcripts involved in alkaloid biosynthesis in opium poppy, Phytochemistry, Volume 64, Issue 1, September 2003, Pages 177- 186, ISSN 0031-9422, 10.1016/S0031-9422(03)00292-9. (http://www.sciencedirect.com/science/article/pii/S0031942203002929) Peter J. Facchini, Sang-Un Park, Developmental and inducible accumulation of gene transcripts involved in alkaloid biosynthesis in opium poppy, Phytochemistry, Volume 64, Issue 1, September 2003, Pages 177- 186, ISSN 0031-9422, 10.1016/S0031-9422(03)00292-9. (http://www.sciencedirect.com/science/article/pii/S0031942203002929) http://opioids.com/timeline/ - Opium: A history, By martin Booth, 1996, Simon & Schuster, Ltd http://www.drugs.com/opium.html - Used for some general information about Opium and Heroin.
  • 19. http://www.flickr.com/photos/cod_gabriel/2223556912/sizes/l/in/photostream/ - Cod_gabriel – dec 24, 2007 http://www.flickr.com/photos/jamesscottbrown/522074884/ - James scott Brown – May 30th 2007 http://www.flickr.com/photos/vculibraries/6032628788/sizes/l/in/photostream/ - VCU Libraries August 11,2011 http://www.flickr.com/photos/planspark/4415256988/ - Planspark – march 7, 2010 http://www.flickr.com/photos/31256440@N07/5618788689/ - Nsikander28 – April 14, 2011 http://www.flickr.com/photos/wdwbarber/534617732/ Bill barker April 27th 2007 http://www.flickr.com/photos/theklan/2316132157/ Mr. Theklan – March 7th, 2008 http://www.flickr.com/photos/theklan/2316132157/ Mr. Theklan – March 7th, 2008