This document discusses the doctrine of sanctification. It defines sanctification as being set apart from sin and unto God. Sanctification is the work of the Holy Spirit in making believers holy by implanting Christian graces and destroying sinful affections. It is not the same as moral virtue or religious practice alone, but is a supernatural, divine work that progressively makes one holy through faith in Christ, the Word, prayer, fellowship and other means. The signs of sanctification and a summons to pursue it are also outlined.