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TISSUES
Definitionof Tissues
Biological tissueisa collection ofinterconnected
cells thatperforma similarfunction within an
organism.
Inotherwords,itisa group of cells working
together mainly inside an organ.
Classification of Tissues
Humanbody iscomposed of
4basic types oftissue:
•Epithelial tissue
•Connective tissue
•Muscular tissue
•Nervous tissue
Origin of Tissue
A fertilized egg divides to produce 3 primary germ cell
layers. These layers differentiate to form the tissues of the
body.
Epithelial Tissue
Epithelialcells cover orline all body surfaces, cavities and
tubes.So,Theseare called covering epithelia.
Epithelialcells formthefunctional unitsofsecretory glands.
So,Theseare called glandular epithelia.
General Characteristic
 Closely attached to each other forming a protectivebarrier.
 Always has one free (apical) surface open to outside the bodyor
inside (cavity) an internal organ.
 Always has one fixed (basal) section attached to underlying
connective tissue.
 Has no blood vessels but can soak up nutrients from bloodvessels
in connective tissue underneath.
 Can have lots of nerves in it (innervated).
 Very good at regenerating (fixing itself). i.e. sunburn, skinned
knee.
Functions
 To protect the tissues that lie beneath it
from radiation, desiccation, toxins, invasion by pathogens,and
physical trauma.
 The regulation and exchange of chemicals between the underlying
tissues and a body cavity.
 The secretion of hormones into the blood vascular system, and/or
the secretion of sweat, mucus, enzymes, and other products thatare
delivered by ducts glandularepithelium.
 To provide sensation.
 Absorbs stomach and intestinal lining (gut).
 Filters the kidney.
Classification of Epithelia
According tothickness
 “simple” - one cell layer
 “stratified”–morethanone layer of cells (whichare
named according totheshape of thecells inthe
apical layer)
According toshape
 “squamous”–widerthan tall
 “cuboidal” –as tallas wide
 “columnar” - taller than wide
Simplesquamous epithelium
Description: Singlelayer of
flattened cells withdisc-shaped
central nuclei and sparse
cytoplasm; thesimplestofthe
epithelia.
Function:Passivetransportofgases
and fluids.
Location:Alveoli oflungs,lining
body cavities (mesothelium),lining
blood vessels (endothelium)
Simplecuboidal epithelia
Description :Single layer of
cubelike cells withlarge,
spherical central nuclei.
Function:Secretion and
absorption.
Location: Kidney tubules;
ducts and secretory portions
ofsmall glands; ovary
surface.
Simplecolumnar epithelia
Description: Singlelayer of tall
cells withround tooval
nuclei.
Types: (i)Ciliated columnar
epithelia.
(ii)Non-ciliated
columnarepithelia.
Function: Absorption;
secretion of mucus,
Enzymes and
other
substances.
Location: Digestive tract, gall
bladder etc.
Stratifiedsquamous epithelia
Description:
Multilayered, surface cell are
squamous, basal cells are
cuboidal and divided
constantly.
Function: Protection.
Location: Oral
cavity, cervix, anal canal.
Stratifiedcuboidal epithelia
Description:Generally two
layers ofcube-like cells.
Function: Protection.
Location: Large ducts ofsweat
glands, mammary glands,
and salivary glands.
Stratifiedcolumnar epithelia
Description:
Multilayered, superficial cells
elongated and columnar.
Function:Protection;
secretion.
Location: Rareinthebody;
small amountinthemale
urethra.
Pseudo stratifiedcolumnar
epithelia
Description: Single cell layered,
all cell attach tothebasement
membrane butnotall reach the
free surface. Nuclei at varying
depth.
Function: Secretion of mucus,
propulsion of mucus by ciliary
action.
Location: Linesof trachea.
Transitionalepithelia
Description:Characterized by
domelike cells thatare neither
squamous norcolumnar. The
formofthecellschanges.
Function:Stretchingand
protection.
Location: Bladder and partof
urethra.
Connective Tissues
Thetissuesthatconnect the differentpartsof the
body together are called connective tissues.
General characteristic
 The intercellular material is maximum where as the
cellular component is minimum.
 Unlike the other tissues, (e.g. epithelium, muscle and
nerve) which are formed mainly by cells, the major
constituent of connective tissue is ECM (Extra-cellular
matrix).
 Possesscells, fibersand groundsubstances.
Basic Functions
 Supportand binding ofother tissues
 Holding body fluids
 Defending thebody against infection
macrophages, plasma cells, mastcells, WBCs
 Storingnutrientsasfat
Classification of connective
tissues
Connective tissueproper :
Loose CT; Areolar
Description: Gel like matrix with
all three fiber types ; cells:
fibroblasts, macrophages, mast
cells, and whiteblood cells.
Function: Its macrophages
phagocytize bacteria ; plays
important role in inflammation ;
holds and conveys tissue fluid.
Distributed under
of body; surrounds
Location:
epithelia
capillaries.
CTproper :Loose CT;Adipose
Description: Matrix as in areolar,
but very sparse; closely packed
adipocytes, orfatcells , have
nucleus pushed to the side by
large fat droplet.
Function: Provides reverse food
fuel; insulates against heat loss;
supportsand protects organs.
Location: Under skin; around
kidneys and eyeballs; within
abdomen; in breasts.
Fat droplets
Nucleus
CTproper: Loose CT; reticular
Description: Network of reticular
fibers in a typical loose ground
substance; reticular cells lie on
the network.
Function: Fibers form a soft internal
skeleton that supports other cell
types including white blood cells,
mastcells, and macrophages.
Location: Lymphoid organs(lymph
nodes, bone marrow, and
macrophages.
CTproper: dense CT; Irregular
Description: Primarily irregularly
arranged collagen fibers; some
elastic fibers; major cell type is
the fibroblast.
Function:Elasticityand structural
support.
Location: Dermis of the skin;
submucosa of digestive tract and
joints.
Collagen
fibers
CTproper: dense CT; Regular
Description: Primarily parallel
collagen fibers; a few elastin
fibers; major cell type is the
fibroblast.
Function: Attaches muscles to
bones and bones to bones.
Location: Tendons and in most
ligaments.
Cartilage: Hyaline
Description: Amorphous but firm
matrix; chondroblasts produce
the matrix and when mature lie
in lacunae.
Supports and
resists compressive
Function:
reinforces;
stress.
Location: Forms most of the
embryonic skeleton; ends of
long bones; cartilages of nose.
Cartilage: Elastic
Description:Similartohyaline
cartilage, butmore elastic
fibersin matrix.
Function:Maintainstheshape
and allows flexibility.
Location: Supportstheexternal
ear(pinna).
Cartilage : Fibrocartilage
Description : Collagen fibers
are predominant ; matrix is
as hyaline butless firm.
Function: High
strength,
tensile
absorb
compressive shock.
Location: Intervertebraldisc;
discs ofknee joint.
Bone
Description: Hard, calcified
matrix containing many
collagen fibers. Very well
vascularized.
Function: Bone supports and
protects; provides levers for
the muscles to act on; stores
calcium and other minerals
and fat; bone marrow is the
siteof blood cell formation.
Location: Skeleton.
Blood
Description:Liquidconnective
tissue,red and whiteblood
cells influid matrix.
Function:Transportrespiratory
gases, nutrients,wastesand
other substances.
Location: Intheblood vessels.
Muscle Tissue
 Muscle is one of our 4 tissue types and muscle tissue
combined with nerves, blood vessels, and various
connective tissues.
 Muscles are quite complex and as we’ll find out, they
are a marvel ofboth biology and physics.
General characteristics
1. Excitability
 Theability toreceive and respond toa stimulus
 Inskeletal muscle, thestimulusisa neurotransmitter
(chemical signal) release by a neuron (nerve cell).
 In smooth muscle, the stimulus could be a
neurotransmitter,a hormone, stretch,pH, Pco2, or
Po2.
 In cardiac muscle, the stimulus could be a
neurotransmitter,a hormone, orstretch.
Theresponse isthe generation of an electrical impulse that
travelsalong theplasma membrane of themuscle cell.
2. Contractility
 Theability toshortenforcibly whenadequately
stimulated.
 Thisisthedefining property ofmuscletissue.
2. Extensibility
 Theability tobe stretched(Extended)
4. Elasticity
 Theability torecoil and resumeoriginal length
afterbeing stretched.
Functions
 Movement
 Locomotion
 Maintains posture
 Produces heat
 Facial expressions
 Pumps blood
 Peristalsis
3TypesofMuscle Tissue
Skeletal Muscle Tissue
Description:Longstriated cells
withmultiplenuclei.
Function:Contraction for
voluntary movements.
Location: Inskeletal muscle.
SmoothMuscle Tissue
Description:Long, spindle-
shaped cells, each witha
single nucleus.
Function:Propulsionof
substancesalong internal
passageways.
Location: Inholloworgans(e.g.
stomach)
Cardiac Muscle tissue
Description:
Branching, striated cells
fused at plasma
membranes.
Pumping of
the circulatory
Function:
blood in
system.
Location: Wallof heart.
Nerve Tissue
Byfarthemostcomplex tissueinthehumanbody is
nerve tissue.
Formed by a network of more than 100 million nerve
cells, assistedby many more glial cells.
Each neuron has, on an average , at least a
thousand interconnection with other neurons forming
a very complex nervous system.
Functions
 Regulates&controlsbody functions
 Generates &transmitsnerveimpulses
 Supports,insulatesand protects impulse
generating neurons.
Composition of Nerve Tissue
Thenerve tissueiscomposed oftwo elements:
1. Thenerve cell orneuron
2. Theneuroglia
Neuron
Description: Neurons are
branching cells; cell processes
that may be quite long extend
from the nucleus-containing cell
body.
Function: Transmit electrical
signals from sensory receptors
and to effectors(muscles and
glands) that control their
activity.
Location: Brain, spinal cord and
nerves.
Glial cells
Glia carry nutrients, speed
repair, provide myelin for
axons, support the blood-
brain barrier, and may form
their own communication
network. They are also
involved in neurogenesis.
References:
1.Gray's Anatomy, 40thEdition
By Susan Standring, PhD, DSc,FKC
2.http://www.highlands.edu/academics/divisions/scipe/biology/labs/rome/
histology
3.http://krupp.wcc.hawaii.edu/BIOL100L/powerpoint/tissues
4.http://www.iteachbio.com/Anatomy-Physiology/BodyTissues
5.http://www.lavc.edu/instructor/watson_k/docs/Tissues
6.http://www.nakedscience.org/mrg/Anatomy%20Unit%204%20-
%20Tissue%20Types
Thank
You ALL

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Anatomy And Physiology of Human tissues

  • 2. Definitionof Tissues Biological tissueisa collection ofinterconnected cells thatperforma similarfunction within an organism. Inotherwords,itisa group of cells working together mainly inside an organ.
  • 3. Classification of Tissues Humanbody iscomposed of 4basic types oftissue: •Epithelial tissue •Connective tissue •Muscular tissue •Nervous tissue
  • 4. Origin of Tissue A fertilized egg divides to produce 3 primary germ cell layers. These layers differentiate to form the tissues of the body.
  • 5. Epithelial Tissue Epithelialcells cover orline all body surfaces, cavities and tubes.So,Theseare called covering epithelia. Epithelialcells formthefunctional unitsofsecretory glands. So,Theseare called glandular epithelia.
  • 6. General Characteristic  Closely attached to each other forming a protectivebarrier.  Always has one free (apical) surface open to outside the bodyor inside (cavity) an internal organ.  Always has one fixed (basal) section attached to underlying connective tissue.  Has no blood vessels but can soak up nutrients from bloodvessels in connective tissue underneath.  Can have lots of nerves in it (innervated).  Very good at regenerating (fixing itself). i.e. sunburn, skinned knee.
  • 7. Functions  To protect the tissues that lie beneath it from radiation, desiccation, toxins, invasion by pathogens,and physical trauma.  The regulation and exchange of chemicals between the underlying tissues and a body cavity.  The secretion of hormones into the blood vascular system, and/or the secretion of sweat, mucus, enzymes, and other products thatare delivered by ducts glandularepithelium.  To provide sensation.  Absorbs stomach and intestinal lining (gut).  Filters the kidney.
  • 8. Classification of Epithelia According tothickness  “simple” - one cell layer  “stratified”–morethanone layer of cells (whichare named according totheshape of thecells inthe apical layer) According toshape  “squamous”–widerthan tall  “cuboidal” –as tallas wide  “columnar” - taller than wide
  • 9.
  • 10. Simplesquamous epithelium Description: Singlelayer of flattened cells withdisc-shaped central nuclei and sparse cytoplasm; thesimplestofthe epithelia. Function:Passivetransportofgases and fluids. Location:Alveoli oflungs,lining body cavities (mesothelium),lining blood vessels (endothelium)
  • 11. Simplecuboidal epithelia Description :Single layer of cubelike cells withlarge, spherical central nuclei. Function:Secretion and absorption. Location: Kidney tubules; ducts and secretory portions ofsmall glands; ovary surface.
  • 12. Simplecolumnar epithelia Description: Singlelayer of tall cells withround tooval nuclei. Types: (i)Ciliated columnar epithelia. (ii)Non-ciliated columnarepithelia. Function: Absorption; secretion of mucus, Enzymes and other substances. Location: Digestive tract, gall bladder etc.
  • 13. Stratifiedsquamous epithelia Description: Multilayered, surface cell are squamous, basal cells are cuboidal and divided constantly. Function: Protection. Location: Oral cavity, cervix, anal canal.
  • 14. Stratifiedcuboidal epithelia Description:Generally two layers ofcube-like cells. Function: Protection. Location: Large ducts ofsweat glands, mammary glands, and salivary glands.
  • 15. Stratifiedcolumnar epithelia Description: Multilayered, superficial cells elongated and columnar. Function:Protection; secretion. Location: Rareinthebody; small amountinthemale urethra.
  • 16. Pseudo stratifiedcolumnar epithelia Description: Single cell layered, all cell attach tothebasement membrane butnotall reach the free surface. Nuclei at varying depth. Function: Secretion of mucus, propulsion of mucus by ciliary action. Location: Linesof trachea.
  • 17. Transitionalepithelia Description:Characterized by domelike cells thatare neither squamous norcolumnar. The formofthecellschanges. Function:Stretchingand protection. Location: Bladder and partof urethra.
  • 18. Connective Tissues Thetissuesthatconnect the differentpartsof the body together are called connective tissues.
  • 19. General characteristic  The intercellular material is maximum where as the cellular component is minimum.  Unlike the other tissues, (e.g. epithelium, muscle and nerve) which are formed mainly by cells, the major constituent of connective tissue is ECM (Extra-cellular matrix).  Possesscells, fibersand groundsubstances.
  • 20. Basic Functions  Supportand binding ofother tissues  Holding body fluids  Defending thebody against infection macrophages, plasma cells, mastcells, WBCs  Storingnutrientsasfat
  • 22. Connective tissueproper : Loose CT; Areolar Description: Gel like matrix with all three fiber types ; cells: fibroblasts, macrophages, mast cells, and whiteblood cells. Function: Its macrophages phagocytize bacteria ; plays important role in inflammation ; holds and conveys tissue fluid. Distributed under of body; surrounds Location: epithelia capillaries.
  • 23. CTproper :Loose CT;Adipose Description: Matrix as in areolar, but very sparse; closely packed adipocytes, orfatcells , have nucleus pushed to the side by large fat droplet. Function: Provides reverse food fuel; insulates against heat loss; supportsand protects organs. Location: Under skin; around kidneys and eyeballs; within abdomen; in breasts. Fat droplets Nucleus
  • 24. CTproper: Loose CT; reticular Description: Network of reticular fibers in a typical loose ground substance; reticular cells lie on the network. Function: Fibers form a soft internal skeleton that supports other cell types including white blood cells, mastcells, and macrophages. Location: Lymphoid organs(lymph nodes, bone marrow, and macrophages.
  • 25. CTproper: dense CT; Irregular Description: Primarily irregularly arranged collagen fibers; some elastic fibers; major cell type is the fibroblast. Function:Elasticityand structural support. Location: Dermis of the skin; submucosa of digestive tract and joints. Collagen fibers
  • 26. CTproper: dense CT; Regular Description: Primarily parallel collagen fibers; a few elastin fibers; major cell type is the fibroblast. Function: Attaches muscles to bones and bones to bones. Location: Tendons and in most ligaments.
  • 27. Cartilage: Hyaline Description: Amorphous but firm matrix; chondroblasts produce the matrix and when mature lie in lacunae. Supports and resists compressive Function: reinforces; stress. Location: Forms most of the embryonic skeleton; ends of long bones; cartilages of nose.
  • 28. Cartilage: Elastic Description:Similartohyaline cartilage, butmore elastic fibersin matrix. Function:Maintainstheshape and allows flexibility. Location: Supportstheexternal ear(pinna).
  • 29. Cartilage : Fibrocartilage Description : Collagen fibers are predominant ; matrix is as hyaline butless firm. Function: High strength, tensile absorb compressive shock. Location: Intervertebraldisc; discs ofknee joint.
  • 30. Bone Description: Hard, calcified matrix containing many collagen fibers. Very well vascularized. Function: Bone supports and protects; provides levers for the muscles to act on; stores calcium and other minerals and fat; bone marrow is the siteof blood cell formation. Location: Skeleton.
  • 31. Blood Description:Liquidconnective tissue,red and whiteblood cells influid matrix. Function:Transportrespiratory gases, nutrients,wastesand other substances. Location: Intheblood vessels.
  • 32. Muscle Tissue  Muscle is one of our 4 tissue types and muscle tissue combined with nerves, blood vessels, and various connective tissues.  Muscles are quite complex and as we’ll find out, they are a marvel ofboth biology and physics.
  • 33. General characteristics 1. Excitability  Theability toreceive and respond toa stimulus  Inskeletal muscle, thestimulusisa neurotransmitter (chemical signal) release by a neuron (nerve cell).  In smooth muscle, the stimulus could be a neurotransmitter,a hormone, stretch,pH, Pco2, or Po2.  In cardiac muscle, the stimulus could be a neurotransmitter,a hormone, orstretch. Theresponse isthe generation of an electrical impulse that travelsalong theplasma membrane of themuscle cell.
  • 34. 2. Contractility  Theability toshortenforcibly whenadequately stimulated.  Thisisthedefining property ofmuscletissue. 2. Extensibility  Theability tobe stretched(Extended) 4. Elasticity  Theability torecoil and resumeoriginal length afterbeing stretched.
  • 35. Functions  Movement  Locomotion  Maintains posture  Produces heat  Facial expressions  Pumps blood  Peristalsis
  • 37. Skeletal Muscle Tissue Description:Longstriated cells withmultiplenuclei. Function:Contraction for voluntary movements. Location: Inskeletal muscle.
  • 38. SmoothMuscle Tissue Description:Long, spindle- shaped cells, each witha single nucleus. Function:Propulsionof substancesalong internal passageways. Location: Inholloworgans(e.g. stomach)
  • 39. Cardiac Muscle tissue Description: Branching, striated cells fused at plasma membranes. Pumping of the circulatory Function: blood in system. Location: Wallof heart.
  • 40. Nerve Tissue Byfarthemostcomplex tissueinthehumanbody is nerve tissue. Formed by a network of more than 100 million nerve cells, assistedby many more glial cells. Each neuron has, on an average , at least a thousand interconnection with other neurons forming a very complex nervous system.
  • 41. Functions  Regulates&controlsbody functions  Generates &transmitsnerveimpulses  Supports,insulatesand protects impulse generating neurons.
  • 42. Composition of Nerve Tissue Thenerve tissueiscomposed oftwo elements: 1. Thenerve cell orneuron 2. Theneuroglia
  • 43. Neuron Description: Neurons are branching cells; cell processes that may be quite long extend from the nucleus-containing cell body. Function: Transmit electrical signals from sensory receptors and to effectors(muscles and glands) that control their activity. Location: Brain, spinal cord and nerves.
  • 44. Glial cells Glia carry nutrients, speed repair, provide myelin for axons, support the blood- brain barrier, and may form their own communication network. They are also involved in neurogenesis.
  • 45. References: 1.Gray's Anatomy, 40thEdition By Susan Standring, PhD, DSc,FKC 2.http://www.highlands.edu/academics/divisions/scipe/biology/labs/rome/ histology 3.http://krupp.wcc.hawaii.edu/BIOL100L/powerpoint/tissues 4.http://www.iteachbio.com/Anatomy-Physiology/BodyTissues 5.http://www.lavc.edu/instructor/watson_k/docs/Tissues 6.http://www.nakedscience.org/mrg/Anatomy%20Unit%204%20- %20Tissue%20Types