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GROWTH OF MANDIBLE
            AND
ITS ROLE IN DEVELOPMENT OF
  ORTHODONTIC PROBLEMS
Growth and development of an
 individual is divided into two periods
Prenatal period
Post natal period
THE PRENATAL LIFE IS DIVIDED
 INTO THREE PERIODS:
1.PERIOD OF THE OVUM
2.PERIOD OF THE EMBRYO
3.PERIOD OF THE FETUS
PRE NATAL GROWTH PHASE

 About the fourth week of
  intrauterine life, the
  pharyngeal arches are
  laid down
 The first arch is called
  the mandibular arch and
  the second arch the
  hyoid arch.
Each of these five arches contain -
1. A central cartilage rod that form the skeleton of
   the arch
2. A muscular component termed as
   bronchomere
3. A vascular component
4. A neural element
INTRAMEMBRANOUS BONE FORMATION

The first structure to develop
in the primodium of the lower
jaw is the mandibular division
of trigeminal nerve that
precedes the mesenchymal
condensation forming the first
[mandibular] arch.
At around 36 -38 days of intrauterine life there is
ectomesenchymal condensation


Some mesenchymal cells enlarges , acquire a
basophilic cytoplasm and form osteoblasts


These osteoblasts secrete a gelatinous matrix
called osteoid and result in ossification of an
osteogenic membrane.
The resulting intramembranous bone lies lateral to meckel’s
cartilage of first [mandibular ] arch.


In the sixth week of the intrauterine life a single ossification
center for each half of the mandible arises in the bifurcation
of inferior alveolar nerve into mental and incisive branches
During seventh week of intrauterine life bone
begin to develop lateral to meckel’s cartilage &
continues until the posterior aspect is covered
with bone


Between eighth & twelfth week of intrauterine
life mandibular growth accelerate , as a result
mandibular length increases.
Ossification stops at a piont , which later become
mandibular lingula, the remaining part of meckels
cartilage continues to form sphenomandibular ligament &
spinous process of sphenoid.


Secondary accseeory cartilage appear between tenth &
fourteenth week of intrauterine life to form head of
condyle , part of coronoid process & mental protuberance
ENDROCHONDRAL BONE FORMATION
   Endrocondral bone formation is seen in 3 areas
   of mandible :
1) The condylar process
2) The coronoid process
3) The mental process
THE CONDYLAR PROCESS:
 At fifth week of intruterine life , an area of
 mesenchymal condensation is seen above the
 ventral part of developing mandible.

 At about tenth week it develops in cone shaped
 cartilage.

 It migrate inferior & fuses with mandibular
 ramus at about 4 month.
This cone shaped cartilage is replaced by bone but
its upper end persists acting as growth cartilage &
articular cartilage.
THE CORONOID PROCESS:
 Secondary accessory cartilage appear in region
 of coronoid process at about 10- 14 week of
 intrauterine life.

 This cartilage become incorporated into
 expanding intramembranous bone of ramus &
 dissapear before birth.
THE MENTAL REGION-
 In mental region , on either side of symphysis ,
 one or two small cartilage appear and ossify in
 seventh week of intrauterine life to become
 mental ossicles.

 These ossicles become incorporated into
 intramembranous bone when symphysis ossify
 completely.
POST NATAL GROWTH PHASE
 At birth the two rami of the mandible are short ,
 condylar development is minimum and there is no
 articular eminence in glenoid fossa. A thin layer of
 fibrocartilage & connective tissue exists at the
 midline of symphysis to separate right & left
 mandibular bodies.


 At fourth month of age and end of first year
 symphysial cartilage is replaced by bone
During first year of life
appositional growth is
active at alveolar border,
at distal & superior
surfaces of the ramus, at
the condyle, along the
lower border of
mandible and on its
lateral surface.
After first year of life these changes
 occur:
• Mandibular growth become more selective , condyle
  shows considerable activities, mandible moves and
  grows downward & forward.

• Appositional growth occurs on posterior border of the
  ramus and on the alveolar process.

• Resorption occurs along the anterior border of ramus
  lengthening the alveolar border & maintaining the
  anterior- posterior dimension of ramus.
Gonial angle changes after little muscle activity.




Transverse dimension is mainly due to growth at
 posterior border in an expanding V pattern.
• Additive growth at coronoid notch , coronoid process & condyle
• Increased superior inter-ramus dimension.
• Alveolar process of mandible grows upward & outward on an
  expanding arc. This permit dental arc to accommodate the larger
  permanent teeth.
Scotts Theory:
   Scott divides the mandible into three
   basic types of bone:
    1)     Basal
    2)     Muscular
    3)     Alveolar

        Basal portion is tube like central foundation running from condyle
         to the symphysis.
        Muscular portion [gonial angle &coronoid process] is under
         influence of masseter, internal pterygoid & temporal muscle. They
         determine the ultimate form of the mandible in these areas.
        Alveolar portion exists to hold the teeth & gradually resorbed in
         the event of tooth loss.
MOSS say that the mandible as a group of
  microskeleton unit :
• Coronoid process as one skeleton unit under influence of
  temporalis.
• Gonial angle is another skeleton unit under influence of massetor
  & internal pterygoid muscles.
• Alveolar process is under the influence of the dentition.
THE CHIN:
• Generalized cortical recession in the flattened
  regions positioned between the canine teeth.

• On lingual surface, behind the chin heavy periosteal
  growth occurs , with the dense lamellar bone
  merging and overlapping on the labial side of the
  chin.

• In male , the apposition of the bone at symphysis
  seems to be about the last change in shape during
  the growing period. This change is much less
  apparent in the females.
Problems of Mandibular Growth and
Their Orthodontic Significance
•   Hypognathism
•   Prognathism
•   Unilateral condylar hypertrophy
•   Bilateral Condylar hypertrophy
•   TMJ Ankylosis
•   Imbalanced Growth
•   Excessive Transverse Growth
•   Poor Transverse Growth
•   Problems of Ramal Growth
•   Problems of Chin Growth
•   Problems of Angle Growth
Hypognathism               • Restricted growth of mandible
Prognathism                • Common in pirre robbin sequence and
Unilateral condylar          patients of cleft lip and palate
hypertrophy
Bilateral Condylar         •   Convex Facial Profile
hypertrophy                •   Hypo divergent face
TMJ Ankylosis              •   Skeletal and Dental Class II malocclusion
Imbalanced Growth          •   Poor airway
Excessive Transverse       •   Increased chances of Cleft lip and Palate
Growth                     •   Increased Nasolabial Angle
Poor Transverse Growth     •   Deep bite
Problems of Ramal Growth   •   Lip in competency
Problems of Chin Growth
Problems of Angle Growth
Hypognathism               • Excessive growth of mandible
Prognathism                • Common in males and in
Unilateral condylar          conditions like acromegaly
hypertrophy
Bilateral Condylar         • Concave facial Profile
hypertrophy                • Hyper divergent face
TMJ Ankylosis              • Dental and Skeletal Class III
Imbalanced Growth            mal occlusion
Excessive Transverse       • Anterior and Posterior Cross
Growth                       bite
Poor Transverse Growth     • Anterior cross bite resulting
Problems of Ramal Growth     in restricted growth of
                             maxilla
Problems of Chin Growth
                           • Increased mandibular corpus
Problems of Angle Growth     length on Ceph
Hypognathism               • Due to some developmental or genetic reasons
Prognathism
Unilateral condylar        • Facial Asymmetry
hypertrophy                • Chin divergent on side opposite to
Bilateral Condylar           hypertrophy
hypertrophy                • Excessive growth at TMJ
TMJ Ankylosis              • Lingual cross bite on one side and buccal cross
Imbalanced Growth            bite on the other side
Excessive Transverse       • Can be corrected with BSSO
Growth
Poor Transverse Growth
Problems of Ramal Growth
Problems of Chin Growth
Problems of Angle Growth
Hypognathism               • Genetic or Hormonal causes
Prognathism
Unilateral condylar        • Common in males
hypertrophy                • Usually expresses in late teen age when the
Bilateral Condylar           growth of mandible continues at condyle
hypertrophy                • Clinical feature similar to mandibular
TMJ Ankylosis                hypertrophy
Imbalanced Growth          • More likely to be a high angle case
Excessive Transverse
Growth
Poor Transverse Growth
Problems of Ramal Growth
Problems of Chin Growth
Problems of Angle Growth
Hypognathism               • Usually because of trauma that results in
Prognathism                  intracapsular bleeding in TMJ
Unilateral condylar        • Can be eight unilateral or bilateral
hypertrophy                • Can be osseous for fibrous
Bilateral Condylar
hypertrophy                • Clinical Features similar to Hypognathism
TMJ Ankylosis              • Limited mouth opening
Imbalanced Growth          • Airway embarrassment
Excessive Transverse
Growth
Poor Transverse Growth
Problems of Ramal Growth
Problems of Chin Growth
Problems of Angle Growth
Hypognathism               • Local Areas of imbalances growth
Prognathism
Unilateral condylar        •   Results in minor facial asymmetry
hypertrophy                •   Shift of midline
Bilateral Condylar         •   Local malocclusions
hypertrophy                •   Crowding or spacing of teeth
TMJ Ankylosis
Imbalanced Growth
Excessive Transverse
Growth
Poor Transverse Growth
Problems of Ramal Growth
Problems of Chin Growth
Problems of Angle Growth
Hypognathism               • Due to genetic reasons
Prognathism                • Common in Prognathic patients
Unilateral condylar
hypertrophy                •   Brachiofacial Appearance
Bilateral Condylar         •   Bilateral Cross bite
hypertrophy                •   Anterior Divergent face
TMJ Ankylosis              •   In severe cases there can be total lingual non
Imbalanced Growth              occlusion – Crocodile bite
Excessive Transverse
Growth
Poor Transverse Growth
Problems of Ramal Growth
Problems of Chin Growth
Problems of Angle Growth
Hypognathism               • Common in Hypognathic patients
Prognathism                • Clinical features similar to hypognathic
Unilateral condylar          patients
hypertrophy
Bilateral Condylar         • Usually class II cases
hypertrophy                • Posterior Divergent faces
TMJ Ankylosis              • In severe cases there can be complete buccal
Imbalanced Growth            non occlusion – Broodie’s Bite
Excessive Transverse
Growth
Poor Transverse Growth
Problems of Ramal Growth
Problems of Chin Growth
Problems of Angle Growth
Hypognathism               • Excessive Vertical Ramal Growth:
Prognathism                  ▫ Bracheofacial Patients
Unilateral condylar          ▫ Low angle cases
hypertrophy                  ▫ Anterior deep bite
Bilateral Condylar         • Poor Vertical Ramal Growth:
hypertrophy                  ▫ Dolicofacial Patients
TMJ Ankylosis                ▫ High Angle Cases
Imbalanced Growth            ▫ Anterio open bite
Excessive Transverse       • Excessive Horizontal Ramal Growth:
Growth                       ▫ More broad oropharynx
Poor Transverse Growth     • Poor Horizontal Ramal Growth:
Problems of Ramal Growth     ▫ Narrow oropharynx
Problems of Chin Growth      ▫ Chances of airway embarrassment
Problems of Angle Growth
Hypognathism               Prominent Chin
Prognathism                •Common in males
Unilateral condylar        •Due to late gonial bone deposition
hypertrophy                •Due to excessive mental bone resorption
Bilateral Condylar         •Can be treated with genioplasty
hypertrophy
TMJ Ankylosis
Imbalanced Growth
Excessive Transverse
Growth
Poor Transverse Growth
Problems of Ramal Growth
Problems of Chin Growth
Problems of Angle Growth
Hypognathism               • Excessive transvers growth
Prognathism                  ▫ Common in males
Unilateral condylar          ▫ Due to excessive bone deposition at angles
hypertrophy                  ▫ Can be corrected with surgery
Bilateral Condylar
hypertrophy
TMJ Ankylosis
Imbalanced Growth
Excessive Transverse
Growth
Poor Transverse Growth
Problems of Ramal Growth
Problems of Chin Growth
Problems of Angle Growth
Significance
• Timely identification of growth disturbances helps in
  interception of developing malocclusions and other
  orthodontic and esthetic facial problems.

• Knowing the timing of development of different facial
  structures gives you idea about the long term facial
  appearance of the patient.

• Timely diagnosis of growth problems gives you a chance
  to treat the problem with functional appliances.

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Mandible

  • 1. GROWTH OF MANDIBLE AND ITS ROLE IN DEVELOPMENT OF ORTHODONTIC PROBLEMS
  • 2. Growth and development of an individual is divided into two periods Prenatal period Post natal period
  • 3. THE PRENATAL LIFE IS DIVIDED INTO THREE PERIODS: 1.PERIOD OF THE OVUM 2.PERIOD OF THE EMBRYO 3.PERIOD OF THE FETUS
  • 4. PRE NATAL GROWTH PHASE  About the fourth week of intrauterine life, the pharyngeal arches are laid down  The first arch is called the mandibular arch and the second arch the hyoid arch.
  • 5. Each of these five arches contain - 1. A central cartilage rod that form the skeleton of the arch 2. A muscular component termed as bronchomere 3. A vascular component 4. A neural element
  • 6. INTRAMEMBRANOUS BONE FORMATION The first structure to develop in the primodium of the lower jaw is the mandibular division of trigeminal nerve that precedes the mesenchymal condensation forming the first [mandibular] arch.
  • 7. At around 36 -38 days of intrauterine life there is ectomesenchymal condensation Some mesenchymal cells enlarges , acquire a basophilic cytoplasm and form osteoblasts These osteoblasts secrete a gelatinous matrix called osteoid and result in ossification of an osteogenic membrane.
  • 8. The resulting intramembranous bone lies lateral to meckel’s cartilage of first [mandibular ] arch. In the sixth week of the intrauterine life a single ossification center for each half of the mandible arises in the bifurcation of inferior alveolar nerve into mental and incisive branches
  • 9. During seventh week of intrauterine life bone begin to develop lateral to meckel’s cartilage & continues until the posterior aspect is covered with bone Between eighth & twelfth week of intrauterine life mandibular growth accelerate , as a result mandibular length increases.
  • 10. Ossification stops at a piont , which later become mandibular lingula, the remaining part of meckels cartilage continues to form sphenomandibular ligament & spinous process of sphenoid. Secondary accseeory cartilage appear between tenth & fourteenth week of intrauterine life to form head of condyle , part of coronoid process & mental protuberance
  • 11. ENDROCHONDRAL BONE FORMATION Endrocondral bone formation is seen in 3 areas of mandible : 1) The condylar process 2) The coronoid process 3) The mental process
  • 12. THE CONDYLAR PROCESS: At fifth week of intruterine life , an area of mesenchymal condensation is seen above the ventral part of developing mandible. At about tenth week it develops in cone shaped cartilage. It migrate inferior & fuses with mandibular ramus at about 4 month.
  • 13. This cone shaped cartilage is replaced by bone but its upper end persists acting as growth cartilage & articular cartilage.
  • 14. THE CORONOID PROCESS: Secondary accessory cartilage appear in region of coronoid process at about 10- 14 week of intrauterine life. This cartilage become incorporated into expanding intramembranous bone of ramus & dissapear before birth.
  • 15. THE MENTAL REGION- In mental region , on either side of symphysis , one or two small cartilage appear and ossify in seventh week of intrauterine life to become mental ossicles. These ossicles become incorporated into intramembranous bone when symphysis ossify completely.
  • 16. POST NATAL GROWTH PHASE At birth the two rami of the mandible are short , condylar development is minimum and there is no articular eminence in glenoid fossa. A thin layer of fibrocartilage & connective tissue exists at the midline of symphysis to separate right & left mandibular bodies. At fourth month of age and end of first year symphysial cartilage is replaced by bone
  • 17. During first year of life appositional growth is active at alveolar border, at distal & superior surfaces of the ramus, at the condyle, along the lower border of mandible and on its lateral surface.
  • 18. After first year of life these changes occur: • Mandibular growth become more selective , condyle shows considerable activities, mandible moves and grows downward & forward. • Appositional growth occurs on posterior border of the ramus and on the alveolar process. • Resorption occurs along the anterior border of ramus lengthening the alveolar border & maintaining the anterior- posterior dimension of ramus.
  • 19.
  • 20. Gonial angle changes after little muscle activity. Transverse dimension is mainly due to growth at posterior border in an expanding V pattern.
  • 21.
  • 22. • Additive growth at coronoid notch , coronoid process & condyle • Increased superior inter-ramus dimension. • Alveolar process of mandible grows upward & outward on an expanding arc. This permit dental arc to accommodate the larger permanent teeth.
  • 23. Scotts Theory: Scott divides the mandible into three basic types of bone: 1) Basal 2) Muscular 3) Alveolar  Basal portion is tube like central foundation running from condyle to the symphysis.  Muscular portion [gonial angle &coronoid process] is under influence of masseter, internal pterygoid & temporal muscle. They determine the ultimate form of the mandible in these areas.  Alveolar portion exists to hold the teeth & gradually resorbed in the event of tooth loss.
  • 24. MOSS say that the mandible as a group of microskeleton unit : • Coronoid process as one skeleton unit under influence of temporalis. • Gonial angle is another skeleton unit under influence of massetor & internal pterygoid muscles. • Alveolar process is under the influence of the dentition.
  • 25. THE CHIN: • Generalized cortical recession in the flattened regions positioned between the canine teeth. • On lingual surface, behind the chin heavy periosteal growth occurs , with the dense lamellar bone merging and overlapping on the labial side of the chin. • In male , the apposition of the bone at symphysis seems to be about the last change in shape during the growing period. This change is much less apparent in the females.
  • 26. Problems of Mandibular Growth and Their Orthodontic Significance • Hypognathism • Prognathism • Unilateral condylar hypertrophy • Bilateral Condylar hypertrophy • TMJ Ankylosis • Imbalanced Growth • Excessive Transverse Growth • Poor Transverse Growth • Problems of Ramal Growth • Problems of Chin Growth • Problems of Angle Growth
  • 27. Hypognathism • Restricted growth of mandible Prognathism • Common in pirre robbin sequence and Unilateral condylar patients of cleft lip and palate hypertrophy Bilateral Condylar • Convex Facial Profile hypertrophy • Hypo divergent face TMJ Ankylosis • Skeletal and Dental Class II malocclusion Imbalanced Growth • Poor airway Excessive Transverse • Increased chances of Cleft lip and Palate Growth • Increased Nasolabial Angle Poor Transverse Growth • Deep bite Problems of Ramal Growth • Lip in competency Problems of Chin Growth Problems of Angle Growth
  • 28. Hypognathism • Excessive growth of mandible Prognathism • Common in males and in Unilateral condylar conditions like acromegaly hypertrophy Bilateral Condylar • Concave facial Profile hypertrophy • Hyper divergent face TMJ Ankylosis • Dental and Skeletal Class III Imbalanced Growth mal occlusion Excessive Transverse • Anterior and Posterior Cross Growth bite Poor Transverse Growth • Anterior cross bite resulting Problems of Ramal Growth in restricted growth of maxilla Problems of Chin Growth • Increased mandibular corpus Problems of Angle Growth length on Ceph
  • 29. Hypognathism • Due to some developmental or genetic reasons Prognathism Unilateral condylar • Facial Asymmetry hypertrophy • Chin divergent on side opposite to Bilateral Condylar hypertrophy hypertrophy • Excessive growth at TMJ TMJ Ankylosis • Lingual cross bite on one side and buccal cross Imbalanced Growth bite on the other side Excessive Transverse • Can be corrected with BSSO Growth Poor Transverse Growth Problems of Ramal Growth Problems of Chin Growth Problems of Angle Growth
  • 30. Hypognathism • Genetic or Hormonal causes Prognathism Unilateral condylar • Common in males hypertrophy • Usually expresses in late teen age when the Bilateral Condylar growth of mandible continues at condyle hypertrophy • Clinical feature similar to mandibular TMJ Ankylosis hypertrophy Imbalanced Growth • More likely to be a high angle case Excessive Transverse Growth Poor Transverse Growth Problems of Ramal Growth Problems of Chin Growth Problems of Angle Growth
  • 31. Hypognathism • Usually because of trauma that results in Prognathism intracapsular bleeding in TMJ Unilateral condylar • Can be eight unilateral or bilateral hypertrophy • Can be osseous for fibrous Bilateral Condylar hypertrophy • Clinical Features similar to Hypognathism TMJ Ankylosis • Limited mouth opening Imbalanced Growth • Airway embarrassment Excessive Transverse Growth Poor Transverse Growth Problems of Ramal Growth Problems of Chin Growth Problems of Angle Growth
  • 32. Hypognathism • Local Areas of imbalances growth Prognathism Unilateral condylar • Results in minor facial asymmetry hypertrophy • Shift of midline Bilateral Condylar • Local malocclusions hypertrophy • Crowding or spacing of teeth TMJ Ankylosis Imbalanced Growth Excessive Transverse Growth Poor Transverse Growth Problems of Ramal Growth Problems of Chin Growth Problems of Angle Growth
  • 33. Hypognathism • Due to genetic reasons Prognathism • Common in Prognathic patients Unilateral condylar hypertrophy • Brachiofacial Appearance Bilateral Condylar • Bilateral Cross bite hypertrophy • Anterior Divergent face TMJ Ankylosis • In severe cases there can be total lingual non Imbalanced Growth occlusion – Crocodile bite Excessive Transverse Growth Poor Transverse Growth Problems of Ramal Growth Problems of Chin Growth Problems of Angle Growth
  • 34. Hypognathism • Common in Hypognathic patients Prognathism • Clinical features similar to hypognathic Unilateral condylar patients hypertrophy Bilateral Condylar • Usually class II cases hypertrophy • Posterior Divergent faces TMJ Ankylosis • In severe cases there can be complete buccal Imbalanced Growth non occlusion – Broodie’s Bite Excessive Transverse Growth Poor Transverse Growth Problems of Ramal Growth Problems of Chin Growth Problems of Angle Growth
  • 35. Hypognathism • Excessive Vertical Ramal Growth: Prognathism ▫ Bracheofacial Patients Unilateral condylar ▫ Low angle cases hypertrophy ▫ Anterior deep bite Bilateral Condylar • Poor Vertical Ramal Growth: hypertrophy ▫ Dolicofacial Patients TMJ Ankylosis ▫ High Angle Cases Imbalanced Growth ▫ Anterio open bite Excessive Transverse • Excessive Horizontal Ramal Growth: Growth ▫ More broad oropharynx Poor Transverse Growth • Poor Horizontal Ramal Growth: Problems of Ramal Growth ▫ Narrow oropharynx Problems of Chin Growth ▫ Chances of airway embarrassment Problems of Angle Growth
  • 36. Hypognathism Prominent Chin Prognathism •Common in males Unilateral condylar •Due to late gonial bone deposition hypertrophy •Due to excessive mental bone resorption Bilateral Condylar •Can be treated with genioplasty hypertrophy TMJ Ankylosis Imbalanced Growth Excessive Transverse Growth Poor Transverse Growth Problems of Ramal Growth Problems of Chin Growth Problems of Angle Growth
  • 37. Hypognathism • Excessive transvers growth Prognathism ▫ Common in males Unilateral condylar ▫ Due to excessive bone deposition at angles hypertrophy ▫ Can be corrected with surgery Bilateral Condylar hypertrophy TMJ Ankylosis Imbalanced Growth Excessive Transverse Growth Poor Transverse Growth Problems of Ramal Growth Problems of Chin Growth Problems of Angle Growth
  • 38. Significance • Timely identification of growth disturbances helps in interception of developing malocclusions and other orthodontic and esthetic facial problems. • Knowing the timing of development of different facial structures gives you idea about the long term facial appearance of the patient. • Timely diagnosis of growth problems gives you a chance to treat the problem with functional appliances.