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MICROBIVORES
- NISHANT YADAV
SHRI RAM MURTI SMARAK COLLEGE OF ENGG. & TECHNOLOGY
PRESENTATION ON
OUTLINE
 Nanorobots
 Types of Nanorobots
 Microbivores
 Applications
 Advantages
 Challenges
 Conclusion
NANOROBOTS
 Integrated and embedded system
 Consists of nanosensors, processors
NANOROBOTS
 Picowatts of power required
 Transmission Antenna of 200nm size
 Sonar communication
TYPES OF NANOROBOTS
 Concept proposed by Dr. Robert A Freitas
 Basic 3 types-
 Respirocytes
 Microbivores
 Clottocytes
RESPIROCYTES
 artificial mechanical red blood cells
 carry oxygen and carbon dioxide molecules
 constructed of 18 bill...
MICROBIVORE
 artificial white blood cell or nanorobotic
phagocytes
 spheroid device 3.4 µm in diameter
 consist of 610...
CLOTTOCYTES
 artificial platelets
 powered by serum-oxyglucose
 reduces the clotting time & blood loss
 performs clot...
MICROBIVORE
STRUCTURE
 Programmed spheroid device
 3.4 µm diameter along MAJOR axis and 2 µm
diameter along MINOR axis
...
MICROBIVORE
 COMPONENTS
 Four basic components -
 Binding sites
 Grapples
 Morcellation chamber
 Digestion chamber
MICROBIVORE
MICROBIVORE
 WORKING
 target bacterium binds to the microbivore
surface via binding sites
 telescopic robotic grapples ...
MICROBIVORE
 the bacterium is internalized into the
morcellation chamber
 bacterium is minced into nanoscale pieces
 re...
MICROBIVORE
 Morcellate is progressively reduced into amino
acids, free fatty acid and simple sugars
by specifically sele...
MICROBIVORE
 Consumes 200 pW power during the operation
 metabolizes local glucose and oxygen for
power or may be extern...
APPLICATIONS
 Drug delivery
 Body surveillance
 Surgery
 Cancer detection and treatment
APPLICATIONS
 Gene therapy
 Diabetes treatment
ADVANTAGES
 Most animal cells are 10,000 to 20,000 nm in
diameter so microbivores are easy to inject
 Glucose or natural...
DISADVANTAGES
 Change in behaviour at nano level,may not be
suitable for body
 High cost
CHALLENGES
 Larger nanoparticles may accumulate in vital
organs
 Nanorobots of larger size will block capillary
flow
CONCLUSION
 The concept of microbivores is just a theoritical
justification till now
 But the recent advancement in the ...
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Microbivores-The future of Nanomedicines

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This presentation will provide you the details of a special category of the so called Medical Nanorobots known as "Microbivores" or the artificial white blood cells.

Veröffentlicht in: Gesundheit & Medizin
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Microbivores-The future of Nanomedicines

  1. 1. MICROBIVORES - NISHANT YADAV SHRI RAM MURTI SMARAK COLLEGE OF ENGG. & TECHNOLOGY PRESENTATION ON
  2. 2. OUTLINE  Nanorobots  Types of Nanorobots  Microbivores  Applications  Advantages  Challenges  Conclusion
  3. 3. NANOROBOTS  Integrated and embedded system  Consists of nanosensors, processors
  4. 4. NANOROBOTS  Picowatts of power required  Transmission Antenna of 200nm size  Sonar communication
  5. 5. TYPES OF NANOROBOTS  Concept proposed by Dr. Robert A Freitas  Basic 3 types-  Respirocytes  Microbivores  Clottocytes
  6. 6. RESPIROCYTES  artificial mechanical red blood cells  carry oxygen and carbon dioxide molecules  constructed of 18 billion atoms  deliever 236 times more oxygen to the body tissues when compared to natural red blood cells  spherical 1 µm diameter sized
  7. 7. MICROBIVORE  artificial white blood cell or nanorobotic phagocytes  spheroid device 3.4 µm in diameter  consist of 610 billion precisely arranged atoms  Traps blood pathogens & breaks them  1000 times faster than white blood cells
  8. 8. CLOTTOCYTES  artificial platelets  powered by serum-oxyglucose  reduces the clotting time & blood loss  performs clotting in approximately 1 sec while the natural time is 4-5 mins
  9. 9. MICROBIVORE STRUCTURE  Programmed spheroid device  3.4 µm diameter along MAJOR axis and 2 µm diameter along MINOR axis  610 billion arranged carbon atoms in diamond structure
  10. 10. MICROBIVORE  COMPONENTS  Four basic components -  Binding sites  Grapples  Morcellation chamber  Digestion chamber
  11. 11. MICROBIVORE
  12. 12. MICROBIVORE  WORKING  target bacterium binds to the microbivore surface via binding sites  telescopic robotic grapples rise up from the surface and attach to the trapped bacterium  grapple’s handoff motion can transport the bacterium from binding site to the ingestion port
  13. 13. MICROBIVORE  the bacterium is internalized into the morcellation chamber  bacterium is minced into nanoscale pieces  remains are pistoned into the digestion chamber which consists of a pre-programmed set of digestive enzymes  These enzymes are injected and extracted 6 times during a single digestion cycle
  14. 14. MICROBIVORE  Morcellate is progressively reduced into amino acids, free fatty acid and simple sugars by specifically selected sequence of 40 enzymes  These small molecules are then discharged into the blood stream through the exhaust port  After the destruction of pathogens the microbivores exits the body through the kidneys and are then excreted in urine
  15. 15. MICROBIVORE  Consumes 200 pW power during the operation  metabolizes local glucose and oxygen for power or may be externally supplied with acoustic power
  16. 16. APPLICATIONS  Drug delivery  Body surveillance  Surgery  Cancer detection and treatment
  17. 17. APPLICATIONS  Gene therapy  Diabetes treatment
  18. 18. ADVANTAGES  Most animal cells are 10,000 to 20,000 nm in diameter so microbivores are easy to inject  Glucose or natural body sugars and oxygen might be a source for propulsion  1000 times faster & 80 times more efficient than natural phagocytes  completely destroy one pathogen in just 30 seconds
  19. 19. DISADVANTAGES  Change in behaviour at nano level,may not be suitable for body  High cost
  20. 20. CHALLENGES  Larger nanoparticles may accumulate in vital organs  Nanorobots of larger size will block capillary flow
  21. 21. CONCLUSION  The concept of microbivores is just a theoritical justification till now  But the recent advancement in the field of nanotechnology gives the hope of the effective use of this technology in medical field  Diseases like AIDs,cancer can be treated permanently at any stage using these technologies  It can be a great replacement for the existing medical technology in terms of fast results and efficiency

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