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H&H Wellness USA
         Product Seminar
(A Hydrogen releasing Supplement)


                                    1
Mechanism of the
Every day we                 身体の仕組み
                           Human Body


       Eat      Absorb nutrients

               Bring oxygen into the
    Breathe    body to be used during
               metabolism.

                Store energy for our
     Sleep         daily activities

                                        2
Mechanism of the
   Nutrients                               Human body
                   Glycolysis Process

   Carbohydrates       Glucose

       Fats
                        Fatty Acid /    Acetyl-CoA
                        Glycerol          Metabolic process
     Proteins          Amino Acid
                                                       H
(3 Major Nutrients)
                                                           H
                                          TCA              CO2
                       ATP                Cycle            H
                                                           H
                                        (Citric Acid Cycle)
                                                               3
Mechanism of the
                                    身体の仕組み
                                  Human Body


ATP (Adenosine Triphosphate) is the
source of all energy for the human body
activities.
Our bodies breathe oxygen and absorb
nutrients in order to retrieve Hydrogen (H).
We need Hydrogen (H) to create ATP.

                                               4
Mechanism of the
                  Human Body




We work and move
with the support of
    Hydrogen.

                                5
Mechanism of the
                              Human Body


                    For a young healthy
60 trillion cells
                           person

       Each cell contains a
       few hundred mitochondrion

             Mitochondria generates
            energy supply for cells
                                                6
Hydrogen protects mitochondrion from oxidation.
      80% of cells die in 1 hour as a result of free radicals.
But with Hydrogen, the death rate decreases to less than 10%.
    Lysosome                                             Mitochondria
    responsible for the                                  Function similar to the
    cell's digestion of                                  power plant of the cell.
    macromolecules, old                                  Food and oxygen reacts
    cell parts, and                                      here and the energy
    microorganisms                                       produced will supply
                                                         for what the cell needs
    Cytoplasm                                            to function.
    The fluid that’s inside the
    membrane of a cell.
                                                          Nucleus
    Contains mostly water,
                                                          The control center of
    from 80 to 97% in
                                                          the cell. It contains a
    different cells
                                                          genetic material called
                                                          DNA.
    Cell Membrane
    Separates a cell from the
    outside environment. It
    surrounds all cells and is
    semi-
    permeable, controlling the
    movement of substances in
    and out of cells
                                  Basic Cell Structure
                                                                                    7
• As we age the repair and regeneration         Energy Source
  capabilities of cells slow down.
• Each day we lose more than 1 billion cells, by
  the age of 70 we have lost over 1/3 of cells.
• The amount of metabolic enzymes also decreases

                                       ・Decrease in energy
                                       ・Stiff neck and shoulders
                                       ・Lower back pain
Our bodies produce less ATP            ・Decrease in libido
                                       ・Wrinkles, brown spots
                                       …etc
   We don’t produce enough
         Hydrogen.
                                                            8
Factors that
                               contribute to illness

 Why do we get sick?

With recent medical discoveries, it is said
that 90% of chronic diseases are caused
by free radicals, which come from the
body’s internal oxidation process over
the years.

                                                  9
Formation of Free Radicals
About 1-3% of oxygen we take in                       Factors that
through breathing alone turns                         contribute to illness
into free radicals.




                                   Free
                                  Radicals




                                                                     10
Free Radicals

Types of Reactive Oxygen          Natural Antioxidant Enzymes
         Species                           in the body
                                                   (Superoxide
  Superoxide Radicals                    SOD       dismutases)


                                                        Glutathione
  Peroxide (Hydrogen Peroxide)           Catalase /     peroxidase



    Hydroxyl Radicals                          None

Hydroxyl Radicals are particularly reactive and damaging to body
  tissues. But the human body doesn’t produce any natural
        antioxidant enzymes to neutralize their effects!
                                                                 11
Benefits of Hydrogen (2) – Anti-oxidation


  Hydrogen can
selectively remove
 Hydroxyl Radicals

                                             12
Supplements



There are plenty of antioxidant supplements
in the market that have been developed to
fight free radicals.

    Vitamin A, Vitamin C, Vitamin E,
    CoQ10, Lutein, Beta-Carotene,
    Green tea supplements …etc

                                             13
Supplements
Potential negatives relating to Supplements:
1) After they have served their anti-oxidation
   properties, they remain as radicals themselves
   (similar to the free radicals).

2) Since they have large molecular sizes they
   may not reach certain parts of the body.

※ Only Hydrogen can pass / penetrate through
  all areas of the body.
                                                       14
The Radical Chain
After completing their antioxation effects, supplements such
as Vitamins, minerals, Catechin, and enzymes will remain in
the body and become a new form of free radicals.

    Fat        ← Vitamin E      ← Vitamin C


                                                  ←Hydrogen


                                                   Discharged
                   Vitamin E        Vitamin C      from the body
Lipoperoxide                                       as WATER
                    Radical          Radical
                                                           15
Benefit of
                                    Hydrogen (2)

       Since Hydrogen converts to
                Water
after it completes its antioxidation effect,
 which is then discharged from the body.
        The antioxidation process is


                 Clean
                                               16
Features of Hydrogen
1)    It is safe and doesn’t leave evasive substances
      behind.
2)    It selectively neutralizes Hydroxyl Radicals
      amongst other free radicals.
3)    It improves metabolic energy.
4)    As the smallest molecular weight element it can
      be transported to every corner of the body.

                                                   17
excellent H & excellent pure
Utilizes natural coral calcium to absorb
and encapsulate Hydrogen. Hydrogen
will be released when the capsule and
coral calcium dissolves in the body.
        A Hydrogen Releasing
            Supplement
                                           18
The Inventors

   Dr. Taneaki OIKAWA (Ph.D)                    Dr. Kokichi HANAOKA (Ph.D)




Department of Biology, Faculty of              Visiting Professor, University of Texas
Science, Yamagata University.                  Medical School, Health Science Center
President of The Institute for Creative
Biotechnology
                                                                                         19
excellent H   excellent pure




                               20

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Product explanation with voice (english)

  • 1. H&H Wellness USA Product Seminar (A Hydrogen releasing Supplement) 1
  • 2. Mechanism of the Every day we 身体の仕組み Human Body Eat Absorb nutrients Bring oxygen into the Breathe body to be used during metabolism. Store energy for our Sleep daily activities 2
  • 3. Mechanism of the Nutrients Human body Glycolysis Process Carbohydrates Glucose Fats Fatty Acid / Acetyl-CoA Glycerol Metabolic process Proteins Amino Acid H (3 Major Nutrients) H TCA CO2 ATP Cycle H H (Citric Acid Cycle) 3
  • 4. Mechanism of the 身体の仕組み Human Body ATP (Adenosine Triphosphate) is the source of all energy for the human body activities. Our bodies breathe oxygen and absorb nutrients in order to retrieve Hydrogen (H). We need Hydrogen (H) to create ATP. 4
  • 5. Mechanism of the Human Body We work and move with the support of Hydrogen. 5
  • 6. Mechanism of the Human Body For a young healthy 60 trillion cells person Each cell contains a few hundred mitochondrion Mitochondria generates energy supply for cells 6
  • 7. Hydrogen protects mitochondrion from oxidation. 80% of cells die in 1 hour as a result of free radicals. But with Hydrogen, the death rate decreases to less than 10%. Lysosome Mitochondria responsible for the Function similar to the cell's digestion of power plant of the cell. macromolecules, old Food and oxygen reacts cell parts, and here and the energy microorganisms produced will supply for what the cell needs Cytoplasm to function. The fluid that’s inside the membrane of a cell. Nucleus Contains mostly water, The control center of from 80 to 97% in the cell. It contains a different cells genetic material called DNA. Cell Membrane Separates a cell from the outside environment. It surrounds all cells and is semi- permeable, controlling the movement of substances in and out of cells Basic Cell Structure 7
  • 8. • As we age the repair and regeneration Energy Source capabilities of cells slow down. • Each day we lose more than 1 billion cells, by the age of 70 we have lost over 1/3 of cells. • The amount of metabolic enzymes also decreases ・Decrease in energy ・Stiff neck and shoulders ・Lower back pain Our bodies produce less ATP ・Decrease in libido ・Wrinkles, brown spots …etc We don’t produce enough Hydrogen. 8
  • 9. Factors that contribute to illness Why do we get sick? With recent medical discoveries, it is said that 90% of chronic diseases are caused by free radicals, which come from the body’s internal oxidation process over the years. 9
  • 10. Formation of Free Radicals About 1-3% of oxygen we take in Factors that through breathing alone turns contribute to illness into free radicals. Free Radicals 10
  • 11. Free Radicals Types of Reactive Oxygen Natural Antioxidant Enzymes Species in the body (Superoxide Superoxide Radicals SOD dismutases) Glutathione Peroxide (Hydrogen Peroxide) Catalase / peroxidase Hydroxyl Radicals None Hydroxyl Radicals are particularly reactive and damaging to body tissues. But the human body doesn’t produce any natural antioxidant enzymes to neutralize their effects! 11
  • 12. Benefits of Hydrogen (2) – Anti-oxidation Hydrogen can selectively remove Hydroxyl Radicals 12
  • 13. Supplements There are plenty of antioxidant supplements in the market that have been developed to fight free radicals. Vitamin A, Vitamin C, Vitamin E, CoQ10, Lutein, Beta-Carotene, Green tea supplements …etc 13
  • 14. Supplements Potential negatives relating to Supplements: 1) After they have served their anti-oxidation properties, they remain as radicals themselves (similar to the free radicals). 2) Since they have large molecular sizes they may not reach certain parts of the body. ※ Only Hydrogen can pass / penetrate through all areas of the body. 14
  • 15. The Radical Chain After completing their antioxation effects, supplements such as Vitamins, minerals, Catechin, and enzymes will remain in the body and become a new form of free radicals. Fat ← Vitamin E ← Vitamin C ←Hydrogen Discharged Vitamin E Vitamin C from the body Lipoperoxide as WATER Radical Radical 15
  • 16. Benefit of Hydrogen (2) Since Hydrogen converts to Water after it completes its antioxidation effect, which is then discharged from the body. The antioxidation process is Clean 16
  • 17. Features of Hydrogen 1) It is safe and doesn’t leave evasive substances behind. 2) It selectively neutralizes Hydroxyl Radicals amongst other free radicals. 3) It improves metabolic energy. 4) As the smallest molecular weight element it can be transported to every corner of the body. 17
  • 18. excellent H & excellent pure Utilizes natural coral calcium to absorb and encapsulate Hydrogen. Hydrogen will be released when the capsule and coral calcium dissolves in the body. A Hydrogen Releasing Supplement 18
  • 19. The Inventors Dr. Taneaki OIKAWA (Ph.D) Dr. Kokichi HANAOKA (Ph.D) Department of Biology, Faculty of Visiting Professor, University of Texas Science, Yamagata University. Medical School, Health Science Center President of The Institute for Creative Biotechnology 19
  • 20. excellent H excellent pure 20

Editor's Notes

  1. Let’s first talk about the mechanisms of the human body. We do these 3 things every day in our lives, we eat, breathe, and sleep. So these activities perform very important functions. We eat, in order to absorb nutrients.We breathe, because oxygen is required during metabolism.We sleep so we can store the energy generated for our daily activities.
  2. - Next let’s continue with the human body mechanisms.- The 3 major nutrients include Carbohydrate, Fat, and Protein. These nutrients then turn into glucose, fatty acid, and amino acid. - The Glycolysis process occurs with Oxygen in the body.This chemical reaction turns these nutrients into AcetyleCoA. - Acetyl-CoA is an important molecule in metabolism. Its main use is to convey the carbon atoms within the acetyl group to the TCA cycle (citric acid cycle) to be oxidized for energy production. This process occurs in the mitochondrian. - The citric acid cycle (TCA Cycle) is a series of enzyme-catalysed chemical reactions, the chemical conversion of these nutrients into carbon dioxide and water to generate a form of usable energy, called ATP.
  3. And Hydrogen is essential when producing ATP.
  4. We mentioned the word Mitochondrian before. You may ask, what is it? Mitochondria can be described as "cellular power plants" because they generate most of our body cell's supply of (ATP),  adenosine triphosphate (ATP), used as a source of chemical energy.[2] In addition to supplying cellular energy, mitochondria are involved in a range of other processes, such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth.[3]
  5. Below is a diagram of a basic cell structure. Hydrogen can protect mitochondrion from oxidation. In fact, 80% of cells die in each hour as a result of free radicalsBut with hydrogen, the death rate decreases to less than 10%
  6. What factors contribute to the forming of free radicals? In fact, about 1-3%...Besides that, ….All contribute to the formation of free radicals.
  7. There are many types of Reactive Oxygen species, the most commonly known include superoxide radicals, peroxide (hydrogen peroxide), and hydroxyl radicals.On the other hand, our bodies also produce natural antioxidant enzymes to protect us from the reactive oxygen species. For example, Superoxide dismutases for superoxide radicals, and catalase / glutathione peroxidase for peroxide or hydrogen peroxide.Unfortunately for hydroxyl radicals, our bodies don’t product any natural enzymes to neutralize their effects. Hydrogen peroxide is reduced to hydroxyl radicals by the enzymes glutathione peroxidase and catalase in the presence of transition metals such iron or copper.  Hydroxyl radicals can cause serious damage to parts of cells such as proteins, DNA, and cell membranes by stealing their electrons through a process called oxidation. The dangers of the hydroxyl radical can be described as"If the function of radicals is to destroy molecules and tissues, then the hydroxyl radical would be the radical's radical. It reacts at diffusion rates with virtually any molecule found in its path including macromolecules such as DNA, membrane lipids, proteins, and carbohydrates. In terms of DNA, the hydroxyl radical can induce strand breaks as well as chemical changes in the DNA structure."
  8. So what can be done about those hydroxyl radicals? The answer lies in Hydrogen.
  9. The blood-brain barrier (BBB) is a separation of circulating blood and cerebrospinal fluid (CSF) maintained by the choroid plexus in the central nervous system (CNS). Endothelial cells restrict the diffusion of microscopic objects (e.g. bacteria) and large or hydrophilic molecules into the CSF, while allowing the diffusion of small hydrophobic molecules (O2, hormones, CO2). Cells of the barrier actively transport metabolic products such as glucose across the barrier with specific proteins.
  10. Let’s continue with the supplement talk. Let me show you how the radical chain works.Let’s look at the diagram below. As an example, we consume fat, when fat is being metabolized a form free radicals called lipoperoxide are produced. So we take Vitamin E to counteract the oxidation effect. And Lipoperoxide turns back into fat.However, after Vitamin E completed its antioxidation mission, it turns into “Vitamin E radical”.So let’s say we take Vitamin C to counteract the oxidation effect. And “Vitamin E radical” turns back into Vitamin E.Next, after Vitamin C completed its antioxidation mission, it remains as Vitamin C radical. This free radical chain continues on and on, Until, we introduce Hydrogen to the chain. Hydrogen provides the vitamin C radical with the missing electron and neutralizes it back into Vitamin C. And after the mission is accomplished, instead of turning into another radical, hydrogen combines with oxygen and is discharged from the body as water.
  11. Try Excellent Pure & Excellent H, and experience the power of hydrogen.