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EMERGENCY DRUGS
Presented by:
Prof Vijayreddy Vandali
Dept of MSN
INDIA
EMERGENCY DRUGS
DRUG INDICATION ROUTE ADULT DOSE PEDIATRIC
DOSE
Oxygen All medical
emergencies
except
hyperventilation
Therapy
mask nasal
cannula
Pocket mask
bag valve
mask
2-6 l/min
10-15 l/min
3-5 l/min
Epinephrine Anaphylaxis IM/SC
IV
1:1000 dilution
0.3-0.5 mg
1: 10,000
dilution
1:1000
0.05-0.3 mg
1:10,000
0.01 mg/kg
Chlorpheniramine
Diphenhydramine
Mild allergy Oral/IM 10-20 mg
25-50 mg
1-2 mg q 6 h
max 8 mg/day
1-1.25 mg/kg
50 mg q 6 h
EMERGENCY DRUGS
DRUG INDICATION ROUTE ADULT DOSE PEDIATRIC
DOSE
Nitroglycerine Angina Sublingual
tablets
Spray
0.4 mg q 5 min
2-3 times
400 μg per
actuation
Amyl nitrate
0.3 mL
vaporole
Salbutamol
(albuterol)
Asthma Metered aerosol
inhaler
100 μg per
actuation
2-3inhalations
/1-2 mn
100 μg per
actuation
1 inhalation/1-2
mn
Aspirin Myocardial
infarction
Sublingual
PO/PR
325 mg tablet 5-10 mg/kg q 6
h
Diazepam Status
epilepticus
Oral
Rectal
2-10 mg
0.2 mg/kg 0.3-0.5 mg/kg
Midazolam IM
Intranasal
Oral/infiltration
/topical
5-10 mg
0.2 mg/kg
5 mg/ml
0.1-0.2 mg/kg
0.2 mg/kg
0.25-0.5 mg/kg
EMERGENCY DRUGS
DRUG INDICATION ROUTE ADULT
DOSE
PEDIATRIC
DOSE
Lorazepam IM/IV 4 mg 0.02-0.04 mg/kg
Morphine
sulfate
Angina
unresponsive to
nitroglycerin
IM/IV
RR<12 Don’t
re-administer
SC
2-5 mg repeat
every 5-30
min
0.05-0.1 mg/kg
max 10 mg/dose
0.1-0.2 mg/kg
Dextrose Hypoglycemia IV 50% dextrose
100 ml
25% dextrose
1-4 ml/kg
Glucagon
50 mL amp
SC/IM/IV 1mg 0.5 mg
Hydrocortisone Adrenal crisis
anaphylaxis
IM/IV 100 mg 1 mg/kg
Dexamethasone IM 4 mg 0.25-0.5 mg/kg
Propranolol Hypertension Oral Immediate
release 40 mg
1-2 mg/kg/day
EMERGENCY DRUGS
DRUG INDICATION ROUTE ADULT
DOSE
PEDIATRIC
DOSE
Atropine Bradycardia IV
IM/SC
0.5-1 mg 0.02 mg/kg
0.04 mg/kg
Aromatic
ammonia
Syncope Inhalant
buds
0.3 ml 0.3 ml
Lidocaine 2% Premature
ventricular
tachycardia
IV
IV/IO/ET
50 or 100 mg
1-1.5 mg/kg
Up to 100 mg
0.5-1 mg/kg
Nifedipine Hypertension
angina
Oral
capsules
10-20 mg 0.25-0.5mg/kg/dose
max 10 mg
Verapamil Hypertension
Supraventricular
tachycardia
IV 2.5 mg/ml
2-4 ml
5-10 mg
0.1-0.3 mg/kg
2-5 mg/dose
Flumazenil Benzodiazepine
overdose
IV 0.2 mg 0.1-0.2 mg
max 1 mg
EMERGENCY DRUGS
DRUG INDICATION ROUTE ADULT
DOSE
PEDIATRIC
DOSE
Naloxone Opioid
overdose
IV
IM
0.4 mg 0.1 mg/mn
0.01 mg/kg
max 0.1-1 mg
Vitamin K Bleeding due to
liver damage
PO/IV/IM/SC 2.5-10 mg 1 mg, SC or IM
Tranexamic
acid
Post-operative
bleeding
IV
PO
Mouth wash
10 mg/kg
25 mg/kg
5%
10 mg/kg
25 mg/kg
Gel foam with
Thrombin/
oxidized
cellulose pack
Topical Available as
variably sized
sheets
Per need
REFERENCES
• https://www.researchgate.net/publication/34
4637452_EMERGENCY_DRUGS
• ubccriticalcaremedicine.ca

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Emergency Drugs PPT

  • 1. EMERGENCY DRUGS Presented by: Prof Vijayreddy Vandali Dept of MSN INDIA
  • 2. EMERGENCY DRUGS DRUG INDICATION ROUTE ADULT DOSE PEDIATRIC DOSE Oxygen All medical emergencies except hyperventilation Therapy mask nasal cannula Pocket mask bag valve mask 2-6 l/min 10-15 l/min 3-5 l/min Epinephrine Anaphylaxis IM/SC IV 1:1000 dilution 0.3-0.5 mg 1: 10,000 dilution 1:1000 0.05-0.3 mg 1:10,000 0.01 mg/kg Chlorpheniramine Diphenhydramine Mild allergy Oral/IM 10-20 mg 25-50 mg 1-2 mg q 6 h max 8 mg/day 1-1.25 mg/kg 50 mg q 6 h
  • 3. EMERGENCY DRUGS DRUG INDICATION ROUTE ADULT DOSE PEDIATRIC DOSE Nitroglycerine Angina Sublingual tablets Spray 0.4 mg q 5 min 2-3 times 400 μg per actuation Amyl nitrate 0.3 mL vaporole Salbutamol (albuterol) Asthma Metered aerosol inhaler 100 μg per actuation 2-3inhalations /1-2 mn 100 μg per actuation 1 inhalation/1-2 mn Aspirin Myocardial infarction Sublingual PO/PR 325 mg tablet 5-10 mg/kg q 6 h Diazepam Status epilepticus Oral Rectal 2-10 mg 0.2 mg/kg 0.3-0.5 mg/kg Midazolam IM Intranasal Oral/infiltration /topical 5-10 mg 0.2 mg/kg 5 mg/ml 0.1-0.2 mg/kg 0.2 mg/kg 0.25-0.5 mg/kg
  • 4. EMERGENCY DRUGS DRUG INDICATION ROUTE ADULT DOSE PEDIATRIC DOSE Lorazepam IM/IV 4 mg 0.02-0.04 mg/kg Morphine sulfate Angina unresponsive to nitroglycerin IM/IV RR<12 Don’t re-administer SC 2-5 mg repeat every 5-30 min 0.05-0.1 mg/kg max 10 mg/dose 0.1-0.2 mg/kg Dextrose Hypoglycemia IV 50% dextrose 100 ml 25% dextrose 1-4 ml/kg Glucagon 50 mL amp SC/IM/IV 1mg 0.5 mg Hydrocortisone Adrenal crisis anaphylaxis IM/IV 100 mg 1 mg/kg Dexamethasone IM 4 mg 0.25-0.5 mg/kg Propranolol Hypertension Oral Immediate release 40 mg 1-2 mg/kg/day
  • 5. EMERGENCY DRUGS DRUG INDICATION ROUTE ADULT DOSE PEDIATRIC DOSE Atropine Bradycardia IV IM/SC 0.5-1 mg 0.02 mg/kg 0.04 mg/kg Aromatic ammonia Syncope Inhalant buds 0.3 ml 0.3 ml Lidocaine 2% Premature ventricular tachycardia IV IV/IO/ET 50 or 100 mg 1-1.5 mg/kg Up to 100 mg 0.5-1 mg/kg Nifedipine Hypertension angina Oral capsules 10-20 mg 0.25-0.5mg/kg/dose max 10 mg Verapamil Hypertension Supraventricular tachycardia IV 2.5 mg/ml 2-4 ml 5-10 mg 0.1-0.3 mg/kg 2-5 mg/dose Flumazenil Benzodiazepine overdose IV 0.2 mg 0.1-0.2 mg max 1 mg
  • 6. EMERGENCY DRUGS DRUG INDICATION ROUTE ADULT DOSE PEDIATRIC DOSE Naloxone Opioid overdose IV IM 0.4 mg 0.1 mg/mn 0.01 mg/kg max 0.1-1 mg Vitamin K Bleeding due to liver damage PO/IV/IM/SC 2.5-10 mg 1 mg, SC or IM Tranexamic acid Post-operative bleeding IV PO Mouth wash 10 mg/kg 25 mg/kg 5% 10 mg/kg 25 mg/kg Gel foam with Thrombin/ oxidized cellulose pack Topical Available as variably sized sheets Per need