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Helping Patients Regulate Their INR
       Helping Warfarin Patients Better
             www.INRTracker.com
             Regulate Their INR
Veronica Coulombe                                      Pavan Katepalli
                       Presented by: Veronica Coulombe & Pavan Katepalli
Co-founder & CEO                                       Co-founder & CTO
              Veronica.Coulombe@inrtracker.com | Pavan.Katepalli@inrtracker.com
Veronica.Coulombe@inrtracker.com                       Pavan.Katepalli@inrtracker.com
                       © Copyright 2012, INR Tracker, www.INRTracker.com
                                                          © Copyright 2012 | www.INRTracker.com
Mission
 According to the New England Journal of Medicine, in
 2009 there were nearly 100,000 adverse drug events
 (ADE) in U.S. impacting adults ages 65 years and older.
   Helping Patients Regulate Their INR
 Warfarin was the number one medication responsible for
 those ADE’s, having caused roughly the same number of
                www.INRTracker.com
 hospitalizations as the other top three drugs combined.1

       INR Tracker strives to provide patients with the
    necessary tools and support to better manage their
Veronica Coulombe    Warfarin treatment
                                    Pavan Katepalli
Co-founder & CEO                   Co-founder & CTO
Veronica.Coulombe@inrtracker.com   Pavan.Katepalli@inrtracker.com
                                    © Copyright 2012 | www.INRTracker.com
Problem
 • Warfarin requires patients to have several tests (INR’s) each month to
   monitor the drugs function within the body. This burden on the patient
   can result in:
     –   Increased medical costs
     –   Reduced quality of life (e.g. lifestyle restrictions and increased bleeding risk)
    Helping Patients Regulate Their INR
     –   Patient dissatisfaction (e.g. inconsistent INR’s)
     –   Discontinuation of highly-efficacious therapy2
 • Patients taking Warfarin have a difficult time managing the drug due to its
                       www.INRTracker.com
   inherent volatility. Warfarin interacts with:
     – Food
     – Prescription medicines
     – Over-the-counter medicines
     – Exercise
     – Weather
     – Coulombe
VeronicaMenstruation                                 Pavan Katepalli
     – And more…
Co-founder & CEO                                     Co-founder & CTO
Veronica.Coulombe@inrtracker.com                     Pavan.Katepalli@inrtracker.com
                                                       © Copyright 2012 | www.INRTracker.com
Solution / Assumptions
 • Solution
     – Provide patients with an at-home drug and dietary
       management system to better handle their Warfarin
       treatment and obtain a consistent INR
 • Helping Patients
   Assumptions                     Regulate Their INR
     – Patients want a tool to help them record their Warfarin
        treatment history
                  www.INRTracker.com
     – Patients want a tool to help them manage their dietary
        needs in conjunction with their Warfarin therapy
     – Patients are willing to give effort to repeatedly record their
        treatment history
     – Coulombe
VeronicaDocumenting their treatment history Katepalli decrease
                                         Pavan will help
Co-founder &burden of being on Warfarin by reducing doctor visits
        the CEO                          Co-founder & CTO
Veronica.Coulombe@inrtracker.com        Pavan.Katepalli@inrtracker.com
                                         © Copyright 2012 | www.INRTracker.com
Target Market
 • Warfarin is the most commonly prescribed oral
   anticoagulant medicine on the market3 and has been in
   use since 1954
 • Helping Patients Regulate Their INR
   Roughly 2 million people take Warfarin each year in the
   United States alone. It is prescribed to patients who are
   at risk of developing blood clots. These conditions
   include:
                   www.INRTracker.com
     – Atrial fibrillation
     – Recurrent strokes
     – Deep venous thrombosis
     – Pulmonary embolism
VeronicaHeart valve replacement4
     – Coulombe                    Pavan Katepalli
Co-founder & CEO                   Co-founder & CTO
Veronica.Coulombe@inrtracker.com   Pavan.Katepalli@inrtracker.com
                                    © Copyright 2012 | www.INRTracker.com
Current Product
 We built a minimum viability product to test and
  de-risk our assumptions
 Our current features enable patients to
     Helping Patients Regulate Their INR
    document:
       – INR readings
       – Doctor appointments
       – Drug dosages, missed dosages, extra
         dosages
       – Exercise
       – Weight
                         www.INRTracker.com
       – Additional custom notes
       – The Vitamin K in 7,906 foods from the
         USDA’s food database
       – Alcohol intake

Veronica Coulombe documentation on
 Patients can view the above
     their personal color-coded calendar & via   Pavan Katepalli
Co-founder & CEO
     reports.                                    Co-founder & CTO
Veronica.Coulombe@inrtracker.com                 Pavan.Katepalli@inrtracker.com
                                                  © Copyright 2012 | www.INRTracker.com
Milestones
 • Formed a solid team with
     complementary skills           User base as of
                                     April 25, 2012
 • Completed core
    Helping Patients Regulate Their INR
     functionality of website
     within 2 months of                             U.S.
     conception                                     Canada

 • Acquired users
                  www.INRTracker.com                U.K.
                                                    India
     immediately upon launch
     via organic methods
 • Continued user growth
Veronica Coulombe             Pavan Katepalli
     with repeat users
Co-founder & CEO              Co-founder & CTO
Veronica.Coulombe@inrtracker.com   Pavan.Katepalli@inrtracker.com
                                    © Copyright 2012 | www.INRTracker.com
Financials
 We take pride in being a lean startup. Total
  startup costs of INR Tracker:
   Helping Patients Date
     Expense        Regulate Their INR
                                Cost
Domain name                   3/22/2012                           $10
Hosting          www.INRTracker.com
                      already existed                             $0
PHP scripts                   3/25/2012                           $65
SEO software                already existed                       $0


Veronica Coulombe
 Total                                    Pavan Katepalli   $75
Co-founder & CEO                          Co-founder & CTO
Veronica.Coulombe@inrtracker.com          Pavan.Katepalli@inrtracker.com
                                              © Copyright 2012 | www.INRTracker.com
Competition
                                  3quibits   Vitamin K Tracker   Dr Gourmet    INR Tracker
Online Tools                                                                     
Apps                                                                            soon
Record INR history                                                               
Record Doctors Appointments                                                      
      Helping Patients Regulate Their INR
Record Drug Dosages
Record Missed Dosages
                                     
                                     
                                                    
                                                    
                                                                 
                                                                 
                                                                                    
                                                                                    
Record Extra Dosages                                                             
Record Weight                                                                    
Record Exercise                                                                  
Record Weather
Custom Reports
                             www.INRTracker.com
                                     
                                     
                                                    
                                                    
                                                                 
                                                                 
                                                                                   soon
                                                                                    
Email Reminders                                                                 soon
Track Vitamin K in Single Foods                                                  
Track Vitamin C in Single Foods                                                  
Track Vitamin E in Single Foods                                                  
Create Custom Meals                                                             soon
Find PremadeCoulombe
Veronica Recipes                                    Pavan Katepalli
                                                                                  soon
Allows Social Communication                                                     soon
Co-founder & CEO                                      Co-founder & CTO
Veronica.Coulombe@inrtracker.com                      Pavan.Katepalli@inrtracker.com
                                                        © Copyright 2012 | www.INRTracker.com
Future Product Features
 Additional Website Features   Mobile & Social
 • Premium paid membership     • Mobile apps to log food, check
 • Better reporting & nutrient   food database, and see overall
   Helping Patients Regulate Their INR
    tracking                     calendar
 • Text message alerts         • Social Network consisting of
 • Email reminders               support
                  www.INRTracker.com badges, user
                                 groups, Q&A,
 • Weather & menstruation
                                 written articles, user
    logger
                                 submitted meals
 • Ability to create custom
                               • Better doctor patient
    meals and find pre made
Veronica Coulombe                communication, articles
                                  Pavan Katepalli
    meals
Co-founder & CEO                    written by doctors &
                                     Co-founder & CTO
Veronica.Coulombe@inrtracker.com    nutritionists
                                     Pavan.Katepalli@inrtracker.com
                                      © Copyright 2012 | www.INRTracker.com
Team
                    Veronica Coulombe | Co-Founder & CEO
                        B.A. in Women's & Gender Studies from Rutgers University.
                        Self taught front-end developer with technical skills including: Dreamweaver,
                        Photoshop, Microsoft Office 2007, XML, HTML, PHP, CSS.
                        Designed the UI and was integral in the product development, marketing, and
                        branding for INR Tracker.
     Helping Patients Regulate Their INR
                        In 2011 I found out the hard way that I have a genetic blood clotting disorder
                        called Factor V Leiden. As a patient of Warfarin, I quickly discovered how
                        difficult of a drug it is to manage. INR Tracker is designed for people like me to
                        better deal with the treatment process.
                        Learn more about me: Linked In
                          www.INRTracker.com
              Pavan Katepalli | Co-Founder & CTO
                  B.A. in Mathematics from Rutgers University.
                  Self taught back-end developer with technical skills including: PHP, MySQL,
                  jQuery, phpMyAdmin.
                  Built a MVP in 2 months from conception and was crucial in the product
                  development and marketing for INR Tracker.
Veronica CoulombeHad a past startup that grew to 300+Pavan Katepallipress on Web Pro
                  News.
                                                      users and received

Co-founder & CEO Learn more about me: Linked In | Blog
                                                     Co-founder & CTO
Veronica.Coulombe@inrtracker.com                              Pavan.Katepalli@inrtracker.com
                                                                © Copyright 2012 | www.INRTracker.com
Thank You
 Thank you for taking the time to view this
   presentation!
 Please contact us if youRegulate Their INR
   Helping Patients have any questions.
     Veronica Coulombe, CEO
               www.INRTracker.com
     Veronica.Coulombe@inrtracker.com
     Pavan Katepalli, CTO
     Pavan.Katepalli@inrtracker.com
Veronica Coulombe                  Pavan Katepalli
Co-founder & CEO                   Co-founder & CTO
Veronica.Coulombe@inrtracker.com   Pavan.Katepalli@inrtracker.com
                                    © Copyright 2012 | www.INRTracker.com
Citations
 1.   Budnitz, Daniel. New England Journal of Medicine, "Emergency Hospitalizations
      for Adverse Drug Events in Older Americans." Last modified November 24, 2011.
      Accessed April 24, 2012.
      http://www.nejm.org/doi/full/10.1056/NEJMsa1103053.
 2. University of Pennsylvania School of Medicine , "Genotyped Guided Dosing of
      Helping Patients Regulate Their INR
      Warfarin Clinical Trial Funding Opportunity - Central Laboratory RFP." Last
      modified July 16, 2008. Accessed April 24, 2012.
      http://rt5.cceb.med.upenn.edu/warfdcc/WARF-1_pg5.html.
 3. IMS Institute for Healthcare Informatics, "The Use of Medicines in the United
      States: Review of 2011, Top Medicines by Prescriptions." Last modified February
                      www.INRTracker.com
      17, 2012. Accessed April 24, 2012.
      http://www.imshealth.com/ims/Global/Content/Insights/IMS Institute for
      Healthcare Informatics/IHII_Medicines_in_U.S_Report_2011.pdf.
 4. University of Wisconsin, Madison, "Pharmaceuticals in Historical
      Context, Warfarin: A Chapter in International Standardization of Therapeutic
      Practices beyond a Commercialized Drug." Last modified October 22-23, 2010.
      Accessed April 24, 2012.
Veronica Coulombe                                   Pavan Katepalli
      http://www.pharmacy.wisc.edu/sites/default/files/private/american-institute-
      history-pharmacy/AIHPconf2010.pdf.
Co-founder & CEO                                    Co-founder & CTO
Veronica.Coulombe@inrtracker.com                  Pavan.Katepalli@inrtracker.com
                                                   © Copyright 2012 | www.INRTracker.com

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INR Tracker Deck

  • 1. Helping Patients Regulate Their INR Helping Warfarin Patients Better www.INRTracker.com Regulate Their INR Veronica Coulombe Pavan Katepalli Presented by: Veronica Coulombe & Pavan Katepalli Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com | Pavan.Katepalli@inrtracker.com Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012, INR Tracker, www.INRTracker.com © Copyright 2012 | www.INRTracker.com
  • 2. Mission According to the New England Journal of Medicine, in 2009 there were nearly 100,000 adverse drug events (ADE) in U.S. impacting adults ages 65 years and older. Helping Patients Regulate Their INR Warfarin was the number one medication responsible for those ADE’s, having caused roughly the same number of www.INRTracker.com hospitalizations as the other top three drugs combined.1 INR Tracker strives to provide patients with the necessary tools and support to better manage their Veronica Coulombe Warfarin treatment Pavan Katepalli Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 3. Problem • Warfarin requires patients to have several tests (INR’s) each month to monitor the drugs function within the body. This burden on the patient can result in: – Increased medical costs – Reduced quality of life (e.g. lifestyle restrictions and increased bleeding risk) Helping Patients Regulate Their INR – Patient dissatisfaction (e.g. inconsistent INR’s) – Discontinuation of highly-efficacious therapy2 • Patients taking Warfarin have a difficult time managing the drug due to its www.INRTracker.com inherent volatility. Warfarin interacts with: – Food – Prescription medicines – Over-the-counter medicines – Exercise – Weather – Coulombe VeronicaMenstruation Pavan Katepalli – And more… Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 4. Solution / Assumptions • Solution – Provide patients with an at-home drug and dietary management system to better handle their Warfarin treatment and obtain a consistent INR • Helping Patients Assumptions Regulate Their INR – Patients want a tool to help them record their Warfarin treatment history www.INRTracker.com – Patients want a tool to help them manage their dietary needs in conjunction with their Warfarin therapy – Patients are willing to give effort to repeatedly record their treatment history – Coulombe VeronicaDocumenting their treatment history Katepalli decrease Pavan will help Co-founder &burden of being on Warfarin by reducing doctor visits the CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 5. Target Market • Warfarin is the most commonly prescribed oral anticoagulant medicine on the market3 and has been in use since 1954 • Helping Patients Regulate Their INR Roughly 2 million people take Warfarin each year in the United States alone. It is prescribed to patients who are at risk of developing blood clots. These conditions include: www.INRTracker.com – Atrial fibrillation – Recurrent strokes – Deep venous thrombosis – Pulmonary embolism VeronicaHeart valve replacement4 – Coulombe Pavan Katepalli Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 6. Current Product We built a minimum viability product to test and de-risk our assumptions Our current features enable patients to Helping Patients Regulate Their INR document: – INR readings – Doctor appointments – Drug dosages, missed dosages, extra dosages – Exercise – Weight www.INRTracker.com – Additional custom notes – The Vitamin K in 7,906 foods from the USDA’s food database – Alcohol intake Veronica Coulombe documentation on Patients can view the above their personal color-coded calendar & via Pavan Katepalli Co-founder & CEO reports. Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 7. Milestones • Formed a solid team with complementary skills User base as of April 25, 2012 • Completed core Helping Patients Regulate Their INR functionality of website within 2 months of U.S. conception Canada • Acquired users www.INRTracker.com U.K. India immediately upon launch via organic methods • Continued user growth Veronica Coulombe Pavan Katepalli with repeat users Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 8. Financials We take pride in being a lean startup. Total startup costs of INR Tracker: Helping Patients Date Expense Regulate Their INR Cost Domain name 3/22/2012 $10 Hosting www.INRTracker.com already existed $0 PHP scripts 3/25/2012 $65 SEO software already existed $0 Veronica Coulombe Total Pavan Katepalli $75 Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 9. Competition 3quibits Vitamin K Tracker Dr Gourmet INR Tracker Online Tools     Apps    soon Record INR history     Record Doctors Appointments     Helping Patients Regulate Their INR Record Drug Dosages Record Missed Dosages         Record Extra Dosages     Record Weight     Record Exercise     Record Weather Custom Reports www.INRTracker.com       soon  Email Reminders    soon Track Vitamin K in Single Foods     Track Vitamin C in Single Foods     Track Vitamin E in Single Foods     Create Custom Meals    soon Find PremadeCoulombe Veronica Recipes   Pavan Katepalli  soon Allows Social Communication    soon Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 10. Future Product Features Additional Website Features Mobile & Social • Premium paid membership • Mobile apps to log food, check • Better reporting & nutrient food database, and see overall Helping Patients Regulate Their INR tracking calendar • Text message alerts • Social Network consisting of • Email reminders support www.INRTracker.com badges, user groups, Q&A, • Weather & menstruation written articles, user logger submitted meals • Ability to create custom • Better doctor patient meals and find pre made Veronica Coulombe communication, articles Pavan Katepalli meals Co-founder & CEO written by doctors & Co-founder & CTO Veronica.Coulombe@inrtracker.com nutritionists Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 11. Team Veronica Coulombe | Co-Founder & CEO B.A. in Women's & Gender Studies from Rutgers University. Self taught front-end developer with technical skills including: Dreamweaver, Photoshop, Microsoft Office 2007, XML, HTML, PHP, CSS. Designed the UI and was integral in the product development, marketing, and branding for INR Tracker. Helping Patients Regulate Their INR In 2011 I found out the hard way that I have a genetic blood clotting disorder called Factor V Leiden. As a patient of Warfarin, I quickly discovered how difficult of a drug it is to manage. INR Tracker is designed for people like me to better deal with the treatment process. Learn more about me: Linked In www.INRTracker.com Pavan Katepalli | Co-Founder & CTO B.A. in Mathematics from Rutgers University. Self taught back-end developer with technical skills including: PHP, MySQL, jQuery, phpMyAdmin. Built a MVP in 2 months from conception and was crucial in the product development and marketing for INR Tracker. Veronica CoulombeHad a past startup that grew to 300+Pavan Katepallipress on Web Pro News. users and received Co-founder & CEO Learn more about me: Linked In | Blog Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 12. Thank You Thank you for taking the time to view this presentation! Please contact us if youRegulate Their INR Helping Patients have any questions. Veronica Coulombe, CEO www.INRTracker.com Veronica.Coulombe@inrtracker.com Pavan Katepalli, CTO Pavan.Katepalli@inrtracker.com Veronica Coulombe Pavan Katepalli Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com
  • 13. Citations 1. Budnitz, Daniel. New England Journal of Medicine, "Emergency Hospitalizations for Adverse Drug Events in Older Americans." Last modified November 24, 2011. Accessed April 24, 2012. http://www.nejm.org/doi/full/10.1056/NEJMsa1103053. 2. University of Pennsylvania School of Medicine , "Genotyped Guided Dosing of Helping Patients Regulate Their INR Warfarin Clinical Trial Funding Opportunity - Central Laboratory RFP." Last modified July 16, 2008. Accessed April 24, 2012. http://rt5.cceb.med.upenn.edu/warfdcc/WARF-1_pg5.html. 3. IMS Institute for Healthcare Informatics, "The Use of Medicines in the United States: Review of 2011, Top Medicines by Prescriptions." Last modified February www.INRTracker.com 17, 2012. Accessed April 24, 2012. http://www.imshealth.com/ims/Global/Content/Insights/IMS Institute for Healthcare Informatics/IHII_Medicines_in_U.S_Report_2011.pdf. 4. University of Wisconsin, Madison, "Pharmaceuticals in Historical Context, Warfarin: A Chapter in International Standardization of Therapeutic Practices beyond a Commercialized Drug." Last modified October 22-23, 2010. Accessed April 24, 2012. Veronica Coulombe Pavan Katepalli http://www.pharmacy.wisc.edu/sites/default/files/private/american-institute- history-pharmacy/AIHPconf2010.pdf. Co-founder & CEO Co-founder & CTO Veronica.Coulombe@inrtracker.com Pavan.Katepalli@inrtracker.com © Copyright 2012 | www.INRTracker.com