it describes the controlled drug release by diffusion or dissolution or both or swelling or erosion and which kinetics it follows either zero,first , higuchi or peppas

1. Submitted by B.VamsikrishnaReddy M.Pharm first year, Pharmaceutics, MCOPS, Manipal. Phone:+91-9008418512 [email_address]

10. R eservoir diffusion system

11. MATRIX DIFFUSION SYSTEMS

14. “ a” indicates reservoir diffusion swelling. “ b” indicates matrix diffusion swelling.

16. This type of drug system dispenses drug solutes continuously at a zero order rate.

19. “ a” indicates bulk erosion “ b” indicates surface erosion

23. Example for environmentally responsive systems

42. ZERO ORDER RELEASE

43. FIRST ORDER RELEASE

44. HIGUCHI MODEL