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ueda2012 idf between serious pandemic and difficult solution-d.adel
1. IDF between serious pandemic
and difficult solutions
Prof. ADEL A EL-SAYED MD
Chair Elect
Middle East and North Africa (MENA) Region
International Diabetes Federation (IDF)
Professor of Internal Medicine
Sohag Faculty of Medicine
Sohag-EGYPT
2. The Story
• Man on earth.
• His dreams: hunger and hard work.
• His achievements: control of food
production – leading a comfortable life.
• The cost.
3. Why diabetes matters
The epidemic
• Already, 366 million people have diabetes and
another 280 millions are at identifiably high risk
of developing diabetes.
• By 2030 this number is expected to rise to 552
millions with diabetes and an additional 398
million people at high risk.
• Three out of four people with diabetes now live
in low-and middle-income countries. Over the
next 20 years, Africa, Middle East and South-East
Asia regions will shoulder the greatest increase in
diabetes prevalence.
4. Why diabetes matters
The epidemic
• Even in rich countries, disadvantaged groups
such as indigenous people and ethnic
minorities, recent migrants and slum dwellers
suffer higher rates of diabetes and its
complications.
• No country, rich or poor, is immune to the
epidemic.
5. Why diabetes matters
Health consequences
• Every seven seconds someone somewhere dies
from diabetes, accounting for more than four
million deaths globally each year.
• Tens of millions more suffer disabling and life-
threatening complications such as heart attack,
stroke, kidney failure, blindness and amputation.
• Diabetes is also implicated in, and has negative
consequences for certain infectious diseases,
other non-communicable diseases (NCDs) and for
mental health.
6. Why diabetes matters
Social and Economic Consequences
• Diabetes is not only a health crisis, it is a
global social catastrophe.
• Governments worldwide are struggling to
meet the cost of diabetes care.
• Costs to employers and national economies
are escalating and every day low-income
families are being driven into poverty by loss
of earnings due to diabetes and the life-long
costs of healthcare.
11. Deaths due to diabetes
• 4.6 million
deaths due to
diabetes in
2011
• 8.2% of all-
cause
mortality
• 48% in people
under 60
12. Healthcare
expenditures
• USD 465 billion
spent on
healthcare for
diabetes
• 11% of all
healthcare
spending is for
diabetes
• USD 1,274 is spent
on diabetes care
per person with
diabetes in 2011
13. Regional highlights
Africa: 78% of people with diabetes are undiagnosed
Europe: the highest prevalence of type 1 diabetes in children
Middle East and North Africa: 6 of the top 10 countries by diabetes
prevalence
North America and Caribbean: 1 adult in 10 has diabetes
South and Central America: 12.3% of all deaths were due to diabetes
South-East Asia: almost one-fifth of the world’s people with diabetes live
in just seven countries
Western Pacific: 132 million adults have diabetes, the largest number of
any region
14.
15. Diabetes and Tuberculosis
• Focused on the linkages between the two
diseases and a review of the evidence
• Calculated the attributable cases of
tuberculosis to diabetes
• Highlights areas where there is a high double
burden
18. IDF
• The International Diabetes Federation (IDF) is
an umbrella organisation of over 200 national
diabetes associations in over 160 countries.
• The Federation has been leading the global
diabetes community since 1950. IDF’s mission
is to promote diabetes care, prevention and a
cure worldwide.
• the International Diabetes Federation (IDF)
has to do something global.
19. The opportunity
• “Preventing and treating diabetes is effective and cost
effective” (WHO, 2005)
• Diabetes and its complications are largely preventable.
There are proven, affordable interventions available.
• Global and national political and business leaders are
increasingly aware of the magnitude and
consequences of the diabetes epidemic.
• There is growing awareness that investing in diabetes
prevention and care brings substantial returns in other
disease areas and in productivity and human
development
20. IDF Initiatives
• Three gobal initiatives:
1- UN General Assembly Resolution December
2006.
2- UN High-Level Summit NCD Meeting September
2011-2021.
3- Global Diabetes Plan 2011 – 2021.
21. UN General Assembly Resolution
• Diabetes is a chronic, debilitating and costly
disease associated with severe complications,
which poses severe risks for families, Member
States and the entire world and serious
challenges to the achievement of internationally
agreed development goals including the
Millennium Development Goals.
• Encourages Member States to develop national
policies for the prevention, treatment and care of
diabetes
22. UN SUMMIT ON NCDS
• The UN High-Level Summit on Non-
Communicable Diseases held on the 19th-20th
September 2011 in New York was a major
milestone in the history of global health and
development.
• A record 34 Heads of State and Government
attended, and 120 Member States made
statements expressing their concern about the
global burden of NCDs and committing
themselves to action.
23. UN SUMMIT ON NCDS
• The Political Declaration on NCD Prevention and
Control was adopted unanimously at the meeting
by 193 Member States.
• The Political Declaration includes a set of
commitments that firmly position diabetes and
NCDs at the top of global and national health and
development agendas.
• For the first time the world's governments have
taken ownership and recognised diabetes and
NCDs as a major challenge in the 21st century
and Committed to global action on this problem.
24. 10 HEADLINE MESSAGES
• National leadership and ownership to drive
progress
• Prioritise early diagnosis and treatment
• Prevention must be the cornerstone of the
response
• Strengthening health systems is of critical
importance
• Enhance the knowledge base through research
and development
25. 10 HEADLINE MESSAGES
• Additional resources required
• Diabetes and NCDs and the global
development agenda
• Collaborative partnerships with NGOs
• Monitoring trends and progress
• Partnerships, reports and reviews to drive
and monitor follow-up action
26. Global Diabetes Plan 2011-2021
• The Global Diabetes Plan was launched in 2011, a
milestone year when world leaders met at UN
headquarters in New York to agree actions on
diabetes and other non-communicable diseases.
• The UN High-Level Summit on NCDs was just the
start. Work will continue to turn political
promises into global action for people who have
diabetes now and to reduce the rate of the
future development of diabetes and its serious
complications.
27. The purpose of the Global Diabetes Plan
1. Reframe the debate on diabetes to further political awareness
of its causes and consequences and the urgent need for
action at the global and country levels.
2. Set out a globally consistent plan to support and guide the
efforts of governments, international donors and IDF member
associations to combat diabetes.
3. Propose proven interventions, processes and partnership for
reducing the personal and societal burden of diabetes.
4. Support and build on existing policies and initiatives such as
the WHO 2008-2013 Action Plan for the Global Strategy for
the Prevention and Control of Non-communicable Diseases.
5. Strengthen the global movement to combat the diabetes
epidemic and to improve the health and lives of people with
diabetes.
28. The objectives
1- Improve health outcomes of people with
diabetes: Early diagnosis, cost effective
treatment and self-management education.
2- Prevent the development of type 2 diabetes:
Lifestyle interventions and socially responsible
policies to promote healthy nutrition and
physical activity.
3- Stop discrimination against people with diabetes:
Supporting legal and policy frameworks and
encouraging awareness of diabetics rights
campaigns.
29. The key strategy
Implement National Diabetes Programmes:
Which are feasible and desirable for all
countries to have, and successful models are
already in place in some countries.
30. Delivering results
- Strengthen institutional frameworks.
- Integrate and optimise human resources and
health services. through training and workforce
development, particularly at primary care level
- Review and streamline supply systems: Optimise
the provision of essential diabetes medicines and
technologies through reliable distribution
systems
- Generate and use research evidence strategically:
apply evidence to policy and practice
31. Delivering results
- Monitor, evaluate and communicate outcomes:
to assess progress.
- Allocate appropriate and sustainable domestic
and international resources: including Official
Development Assistance (ODA) for low-and
middle-income countries.
- Adopt a whole of society approach: Engage
governments, the private sector and civil society
(including healthcare workers, academia and
people with diabetes) in working together to turn
the tide on diabetes.
32. Global Diabetes Plan
• We already have the evidence. Now, with the
Global Diabetes Plan in our hands, we are one
step closer to stopping avoidable deaths and
reducing the suffering caused by diabetes.
New in this edition:
China takes the top spot, with India close behind. This is heavily influenced by the new study published in 2010. Our estimates are just under theirs at 90 million (compared to 91 million) and can be attributed to different age groups and a somewhat more conservative approach.
Increases and changes in the position of countries relative to each other can be explained mostly by an ageing population and changes in urbanisation.
Note, the BRIC countries are all in the top 10. Only the US is a high-income country.
The Pacific Islands and MENA dominate this category. The rates are more than twice the global average. Changes again only take into account changes in the population structure and urbanisation. For Pacific Islands, urbanisation is 100% so it is just age changes that can be expected.
New for this edition:
IMPORTANT: Nauru is no longer number 1
This is due not only to new data from the region, but may also reflect the effects of mortality due to diabetes.
The emergence of MENA – 6 out of the 10 countries are in MENA
Biggest changes will be in Africa, followed very closely by MENA. NAC and Europe will change the least.
We used reports coming from the original population-based studies that tell us what proportion of the prevalence from the study were found to have diabetes at the time of the survey. The vast majority of these are people with type 2 diabetes, but undiagnosed type 1 diabetes is not unheard of, although it is of short duration, generally.
In order to provide more accurate estimates for regions, and especially where data were lacking, we decided to create estimates of the proportion of undiagnosed (%) for each region and income group. For all the studies that provided data and had a sufficient quality, we took the median value of all studies within that region and income group. This allowed us to control for the skew of the data rather than if we took the mean. So if one study reported a number that was very different from all the others, it wouldn’t pull our estimate in that direction.
Low-income countries in Africa have the highest estimated proportion of undiagnosed diabetes (77.9%) However, for any one region and income group, the proportion of undiagnosed diabetes was at least 27%. This is very high and likely an underestimate. Globally, half of all cases of diabetes are undiagnosed. Over 60% of all people with undiagnosed diabetes are in the Western Pacific and South-East Asia Regions.
More deaths due to diabetes than HIV/AIDS, malaria, and tuberculosis combined.
GENDER
There is no difference in the total number of deaths due to DM in men and women. But there are differences in the distributions.
Diabetes accounts for a higher proportion in women than in men. This is due mostly to a higher rate of mortality from other causes in men than in women.
TRENDS
A 13.3% increase over the 4th edition, due mostly to higher prevalence of diabetes in several regions. There has been a documented decline in the deaths due to other NCDs in the world, but no similar decline for diabetes.
ACCURACY
The estimates use prevalence data combined with the relative risk of death from diabetes by age and region from existing mortality data. It certainly has gaps but is more accurate than that for diabetes from health statistics. This is because those statistics collect data from death reports and diabetes is rarely listed as the cause of death on a certificate, even though it may have been the underlying cause.
The maps show us countries were there is high spending per person with diabetes, and high total spending on diabetes.
The healthcare expenditures measure includes medical spending on diabetes by the health system as well as by people with diabetes. It does not include the indirect costs to society from lost productivity, absences from work, and the associated costs of care. In other words, this is a big underestimate of the true cost of diabetes.
It is also important to note that some of this spending is necessary as part of care. However, some studies show that families pay 40-60% of medical care expenditures out of their own pockets for diabetes, which shows a disproportionate amount of the cost is borne by people with diabetes and their caregivers.
The differences in spending are almost the exact reverse of the mortality and prevalence data. High-income countries have a much higher total spending that any of the middle- or low-income countries. This additional spending is probably contributing to the lower mortality rate, prevalence, and total deaths. In addition, mean spending on diabetes per case is much higher in high-income than in any of the other groups. In low-income, it is almost non-existent.
Diabetes increases the chances of developing tuberculosis by 2.5 times at least.
A person with diabetes and tuberculosis is more likely to fail tuberculosis treatment and more likely to die from tuberculosis than a person without diabetes.
Using the fact that we know that a person with diabetes has 2.5 times the chances of developing tuberculosis, we can calculate how much tuberculosis in a country may be due to diabetes. We see that for countries with a high burden of diabetes and a relatively low burden of tuberculosis, a large proportion of tuberculosis cases may be attributable to diabetes. Conversely, countries with a low diabetes burden will have fewer tuberculosis cases related to diabetes.