1. Project: CD4 1
Accession # M12807
2. Brady RL, Dodson EJ, Dodson GG, Lange G, Davis SJ, Williams AF, Barclay AN.
Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains.
Science. 1993 May 14;260(5110):979-83
2. C. Pitcher, S. Honing, A. Fingerhut, K. Bowers, M. Marsh
Mol. Biol. Cell 10, 677 (1999).
16
84
130
159
300
345
271
370
396
303
N-linked Glycosylation sites
S
S
S
S
S
S D4
D3
D2
D1
433
Serine 408
Phos, lck dissociation
and internalization2
Cysteine 420/22
Lck binding
CD4
Cysteine 396/99
Palmitoylation/Lipid Raft Association1
2. R. Fragoso, D. Ren, X, Zhang, M. Wei-Chih Su, S.J. Burakoff, Y-J Jin
J. Immunol 170, 913 (2003).