LaparoscopicEsophagealEpiphrenicDiverticulectomyWithCardiomyotomy and Anterior Partial Fundoplication

Epiphrenic diverticulum is a rare disease, located usually in the distal esophagus on the right side. The majority are associated with achalasia. Surgery treats the diverticulum and the underlying motility disorder, thus the association: diverticulectomy, cardiomyotomy and wrap construction.Epiphrenic Diverticulum (ED) is a rare entity of the distal esophagus. It is treated with laparoscopic transabdominal approach with excellent results. We report the case of a 59-yearold male with ED who presented with dysphagia over the last year. He was treated with laparoscopic diverticulectomy, cardiomyotomy and anterior partial fundoplication. He remains asymptomatic after 2 years follow up.

Copyright: © 2019 Darazi E, et al. Volume 1 | Issue 3
Case Report Open Access
American Journal of Surgery and Clinical Case Reports
LaparoscopicEsophagealEpiphrenicDiverticulectomyWithCardiomyotomy
and Anterior Partial Fundoplication
Darazi E1
and El-Khoury E2
1
Department of Nutrition, Holy Spirit University of Kaslik USEK- Kaslik- Lebanon
2
Department of General Suirgery, Elias El-Khoury, M.D, FACS, FEBS. Central Military Hospital, Beirut, Lebanon.
*Correspondingauthor:ElhamDarazi,DepartmentofNutrition,HolySpiritUniversityofKaslikUSEK-Kaslik-Leba-
non. E-mail: ilhamdarazi@hotmail.com
Citation: Darazi E (2019) Laparoscopic Esophageal Epiphrenic Diverticulectomy With Cardiomyotomy and Anterior
Partial Fundoplication. American Journal of Surgery and Clinical Case Reports. V1(3): 1-3.
Received Date: Oct 17, 2019 Accepted Date: Nov 20, 2019 Published Date: Nov 30, 2019
1. Abstract
Epiphrenic Diverticulum (ED) is a rare entity of the distal
esophagus. It is treated with laparoscopic transabdominal
approach with excellent results. We report the case of a 59-year-
old male with ED who presented with dysphagia over the
last year. He was treated with laparoscopic diverticulectomy,
cardiomyotomy and anterior partial fundoplication. He
remains asymptomatic after 2 years follow up.
2. Keywords: Epiphrenic diverticulum; Achalasia;
Cardiomyotomy; Anterior Partial Fundoplication
3. Introduction
Epiphrenic diverticulum is a rare disease, located usually
in the distal esophagus on the right side. The majority are
associated with achalasia. Surgery treats the diverticulum
and the underlying motility disorder, thus the association:
diverticulectomy, cardiomyotomy and wrap construction.
4. Case Presentation
A 59-year-old man presented to our department complaining
of dysphagia for one year. Barium swallow (Figure 1) and
esophagogastroscopy showed a distal esophageal diverticulum
located at 2 cm from the gastroesophageal junction on the
right side. High resolution manometry revealed the presence
of concomittent achalasia. Under general anaesthesia in a
modified lithotomy position and the surgeon between patient’s
legs, five trocars were used :one supraumbilical 11mm camera
port, one 12mm and one 5mm working ports at left and right
hypochondrium respectively, one 5mm left anterior axillary
retraction port and one 5mm subxiphoid for liver retraction.
The abdominal oesophagus was fully mobilised with hiatal
dissection followed by a wide mediastinal dissection. The
diverticulum was identified and dissected from the adjacent
muscles (Figure 2). The posterior right vagus is identified
(Figure 3) and dissected off the diverticulum base (Figure
4). After peroperative esophagoscopy (Figure 5), the ED was
excised by a stapling device (Figure 6). Heller cardiomyotomy
was done and extended 8 cm and 3 cm through the muscles of
the esophagus and stomach respectively (Figure 7). Anterior
partial fundoplication was done and fixed to the cruras (Figure
8). The patient was discharged uneventfully the third day with
no signs of leak clinically or radiographically and was followed
by our nutrition departement. Histopathological findings were
consistent with ED. At 2 years follow up, the patient is still
asymptomatic.
Figure 1: Right sided epiphrenic diverticulum
Figure 2: ED herniating through the esophageal muscles (arrow)
ajsccr.org 2
Volume 1 | Issue 3
Figure 3: Right vagus nerve at the base of the ED
Figure 4: Vagus (arrow) dissected from the base of the ED (elevated by the
grasper)
Figure 5: Esophagoscopy ruling out residual alimentary debris
Figure 6: Stapling and excision of the ED with preservation of the vagus nerve
(arrow)
Figure 7: Cardiomyotomy
Figure 8: Anterior partial fundoplication
5. Discussion
Epiphrenic diverticulum is a rare entity with a prevalence
between 0.0015% and 2% [1] usually located in the distal
esophagus on the right side[2].It is a pulsion diverticula [3]
with herniation of the mucosa and submucosa through the
muscular layers. [4] Mainly asymptomatic, only 20% of patients
are symptomatic. [5,6] Dysphagia, regurgitation, and chest pain
can develop, with dysphagia being the most common.[7] Since
the first report in 1998 by Rosati et al, surgery became the best
curative option [8] varying from transthoracic to laparoscopic
approaches[9]. Nowadays the use of laparoscopy is considered
the approach of choice in most cases[10] as it is very efficient
in improving symptoms[11] with laparoscopic transhiatal
diverticulectomy, myotomy and anterior partial fundoplication
producing symptomatic relief in 85-100% of cases,[8]thus
making it the best surgical approach for this case.[12]Surgery
is indicated to treat symptomatic patients and to prevent
complications in asymptomatic ones.[4,13-15]Perforation,
progression to carcinoma,[15,16] esophagopulmonary fistula
[17] aspiration pneumonia, and lung abscess[18]are all possible
complications that can appear if left untreated.
The diagnostic workup includes barium swallow to define the
location and the size of the diverticulum[4], upper endoscopy to
exclude malignancy of the distal oesophagus and oesophageal
manometry to identify any underlying motility disorder[19]
since the majority of ED are secondary to esophageal motility
disorders[4,11,18] mainly achalasia[13].
5.1 Specific Technical Points Should be Considered in ED
Surgery
Before stapling it is essential to dissect the posteriorly situated
right vagus nerve off the ED base, to prevent encorching it
and peroperative esophagoscopy must be done to exclude
any residual alimentary debris that can be present due to the
associated esophageal motilitydisorder.
The myotomy should be long enough to eliminate any residual
intraesophageal hyperpressure that highers the risk of leak
and mediastinitis. The mediastinal dissection should be very
wide to eliminate upwards traction so that the esophagus can
lie passively well below the diaphragm, under the abdominal
positive pressure, decresing the risk of postoperative reflux, and
the wrap should be fixed to the crura.
ajsccr.org 3
Volume 1 | Issue 3
References
1. Andrasi L, Paszt A, Simonka Z, Abraham S, Rosztoczy A, Lazar G.
Laparoscopic Surgery for Epiphrenic Esophageal Diverticulum. JSLS.
2018; 22: e2017.00093.
2. Tedesco P, Fisichella PM, Way LW, Patti MG. Cause and treatment
of epiphrenic diverticula. Am J Surg. 2005;190: 891-4.
3. Gonzalez-Calatayud M, Targarona EM, Balague C, Rodriguez-Luppi
C, Martin AB, Trias M. Minimally invasive therapy for epiphrenic
diverticula: systematic review of literature and report of six cases. J
Minim Access Surg. 2014; 10: 169-74.
4. Soares R, Herbella FA, Prachand VN, Ferguson MK, Patti MG.
Epiphrenic diverticulum of the esophagus. From pathophysiology to
treatment. J Gastrointest Surg. 2010; 14: 2009-15.
5. Zaninotto G, Portale G, Costantini M, Zanatta L, Salvador R, Ruol
A. Therapeutic strategies for epiphrenic diverticula: systematic review.
World J Surg. 2011; 35: 1447-53.
6. Fernando HC, Luketich JD, Samphire J, Alvelo-Rivera M, Christie
NA, Buenaventura PO et al. Minimally invasive operation for
esophageal diverticula. Ann Thorac Surg. 2005; 80: 2076-80.
7. Herbella FA, Patti MG. Modern pathophysiology and treatment of
esophageal diverticula. Langenbecks Arch Surg. 2012; 397: 29-35.
8. Herbella FA, Patti MG. Achalasia and epiphrenic diverticulum.
World J Surg. 2015; 39: 1620-4.
9. Hirano Y,Takeuchi H, Oyama T,Saikawa Y,Niihara M, Sako H et al.
Minimally invasive surgery for esophageal epiphrenic diverticulum:
the results of 133 patients in 25 published series and our experience.
Surg Today. 2013; 43:1-7.
10. Tapias LF, Morse CR, Mathisen DJ, Gaissert HA, Wright CD,
Allan JS, Lanuti M. Surgical Management of Esophageal Epiphrenic
Diverticula: A Transthoracic Approach Over Four Decades. Ann
Thorac Surg. 2017; 104:1123-30.
11. D’Journo XB, Ferraro P, Martin J, Chen LQ, Duranceau A.
Lower oesophageal sphincter dysfunction is part of the functional
abnormality in epiphrenic diverticulum. Br J Surg. 2009; 96: 892-900.
12. Rossetti G, Fei L, del Genio G, Maffettone V, Brusciano L, Tolone
S, et al. Epiphrenic diverticula mini-invasive surgery: a challenge for
expert surgeons-personal experience and review of the literature.
Scand J Surg. 2013; 102: 129-35.
13. FisichellaPM,JalilvandA,Dobrowolsky A.Achlasiaandepiphrenic
diverticulum. World J Surg. 2015; 39: 1614-9.
14. Thomas ML, Anthony AA, Fosh BG, Finch JG, Maddern GJ.
Oesophageal diverticula. Br J Surg. 2001; 88: 629-42.
15. Altorki NK, Sunagawa M, Skinnaer DB. Thoracic esophageal
diverticula. Why is operation necessary? J Thorac Cardiovasc Surg.
1993; 10: 260-4.
16. Lai ST,Hsu CP.Carcinoma arising from an epiphrenic diverticulum:
a frequently misdiagnosed disease. Ann Thorac Cardiovasc Surg.
2007; 13: 110-3.
17. Herbella FA, Del Grande JC. Benign esophagopulmonary fistula
through an epiphrenic diverticulum and asymptomatic achalasia. Dig
Dis Sci. 2010; 55:1177-8.
18. Vicentine FP, Herbella FA, Silva LC, Patti MG. High resolution
manometry findings in patients with esophageal epiphrenic
diverticula. Am Surg. 2011; 77: 1661-4.
19. Sato H, Takahashi K, Mizuno KI, Hashimoto S, Yokoyama J,
Hasegawa G, Terai S. Esophageal motility disorders: new perspectives
from high-resolution manometry and histopathology. J Gastroenterol.
2018; 53: 484-93.

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LaparoscopicEsophagealEpiphrenicDiverticulectomyWithCardiomyotomy and Anterior Partial Fundoplication

  • 1. Copyright: © 2019 Darazi E, et al. Volume 1 | Issue 3 Case Report Open Access American Journal of Surgery and Clinical Case Reports LaparoscopicEsophagealEpiphrenicDiverticulectomyWithCardiomyotomy and Anterior Partial Fundoplication Darazi E1 and El-Khoury E2 1 Department of Nutrition, Holy Spirit University of Kaslik USEK- Kaslik- Lebanon 2 Department of General Suirgery, Elias El-Khoury, M.D, FACS, FEBS. Central Military Hospital, Beirut, Lebanon. *Correspondingauthor:ElhamDarazi,DepartmentofNutrition,HolySpiritUniversityofKaslikUSEK-Kaslik-Leba- non. E-mail: ilhamdarazi@hotmail.com Citation: Darazi E (2019) Laparoscopic Esophageal Epiphrenic Diverticulectomy With Cardiomyotomy and Anterior Partial Fundoplication. American Journal of Surgery and Clinical Case Reports. V1(3): 1-3. Received Date: Oct 17, 2019 Accepted Date: Nov 20, 2019 Published Date: Nov 30, 2019 1. Abstract Epiphrenic Diverticulum (ED) is a rare entity of the distal esophagus. It is treated with laparoscopic transabdominal approach with excellent results. We report the case of a 59-year- old male with ED who presented with dysphagia over the last year. He was treated with laparoscopic diverticulectomy, cardiomyotomy and anterior partial fundoplication. He remains asymptomatic after 2 years follow up. 2. Keywords: Epiphrenic diverticulum; Achalasia; Cardiomyotomy; Anterior Partial Fundoplication 3. Introduction Epiphrenic diverticulum is a rare disease, located usually in the distal esophagus on the right side. The majority are associated with achalasia. Surgery treats the diverticulum and the underlying motility disorder, thus the association: diverticulectomy, cardiomyotomy and wrap construction. 4. Case Presentation A 59-year-old man presented to our department complaining of dysphagia for one year. Barium swallow (Figure 1) and esophagogastroscopy showed a distal esophageal diverticulum located at 2 cm from the gastroesophageal junction on the right side. High resolution manometry revealed the presence of concomittent achalasia. Under general anaesthesia in a modified lithotomy position and the surgeon between patient’s legs, five trocars were used :one supraumbilical 11mm camera port, one 12mm and one 5mm working ports at left and right hypochondrium respectively, one 5mm left anterior axillary retraction port and one 5mm subxiphoid for liver retraction. The abdominal oesophagus was fully mobilised with hiatal dissection followed by a wide mediastinal dissection. The diverticulum was identified and dissected from the adjacent muscles (Figure 2). The posterior right vagus is identified (Figure 3) and dissected off the diverticulum base (Figure 4). After peroperative esophagoscopy (Figure 5), the ED was excised by a stapling device (Figure 6). Heller cardiomyotomy was done and extended 8 cm and 3 cm through the muscles of the esophagus and stomach respectively (Figure 7). Anterior partial fundoplication was done and fixed to the cruras (Figure 8). The patient was discharged uneventfully the third day with no signs of leak clinically or radiographically and was followed by our nutrition departement. Histopathological findings were consistent with ED. At 2 years follow up, the patient is still asymptomatic. Figure 1: Right sided epiphrenic diverticulum Figure 2: ED herniating through the esophageal muscles (arrow)
  • 2. ajsccr.org 2 Volume 1 | Issue 3 Figure 3: Right vagus nerve at the base of the ED Figure 4: Vagus (arrow) dissected from the base of the ED (elevated by the grasper) Figure 5: Esophagoscopy ruling out residual alimentary debris Figure 6: Stapling and excision of the ED with preservation of the vagus nerve (arrow) Figure 7: Cardiomyotomy Figure 8: Anterior partial fundoplication 5. Discussion Epiphrenic diverticulum is a rare entity with a prevalence between 0.0015% and 2% [1] usually located in the distal esophagus on the right side[2].It is a pulsion diverticula [3] with herniation of the mucosa and submucosa through the muscular layers. [4] Mainly asymptomatic, only 20% of patients are symptomatic. [5,6] Dysphagia, regurgitation, and chest pain can develop, with dysphagia being the most common.[7] Since the first report in 1998 by Rosati et al, surgery became the best curative option [8] varying from transthoracic to laparoscopic approaches[9]. Nowadays the use of laparoscopy is considered the approach of choice in most cases[10] as it is very efficient in improving symptoms[11] with laparoscopic transhiatal diverticulectomy, myotomy and anterior partial fundoplication producing symptomatic relief in 85-100% of cases,[8]thus making it the best surgical approach for this case.[12]Surgery is indicated to treat symptomatic patients and to prevent complications in asymptomatic ones.[4,13-15]Perforation, progression to carcinoma,[15,16] esophagopulmonary fistula [17] aspiration pneumonia, and lung abscess[18]are all possible complications that can appear if left untreated. The diagnostic workup includes barium swallow to define the location and the size of the diverticulum[4], upper endoscopy to exclude malignancy of the distal oesophagus and oesophageal manometry to identify any underlying motility disorder[19] since the majority of ED are secondary to esophageal motility disorders[4,11,18] mainly achalasia[13]. 5.1 Specific Technical Points Should be Considered in ED Surgery Before stapling it is essential to dissect the posteriorly situated right vagus nerve off the ED base, to prevent encorching it and peroperative esophagoscopy must be done to exclude any residual alimentary debris that can be present due to the associated esophageal motilitydisorder. The myotomy should be long enough to eliminate any residual intraesophageal hyperpressure that highers the risk of leak and mediastinitis. The mediastinal dissection should be very wide to eliminate upwards traction so that the esophagus can lie passively well below the diaphragm, under the abdominal positive pressure, decresing the risk of postoperative reflux, and the wrap should be fixed to the crura.
  • 3. ajsccr.org 3 Volume 1 | Issue 3 References 1. Andrasi L, Paszt A, Simonka Z, Abraham S, Rosztoczy A, Lazar G. Laparoscopic Surgery for Epiphrenic Esophageal Diverticulum. JSLS. 2018; 22: e2017.00093. 2. Tedesco P, Fisichella PM, Way LW, Patti MG. Cause and treatment of epiphrenic diverticula. Am J Surg. 2005;190: 891-4. 3. Gonzalez-Calatayud M, Targarona EM, Balague C, Rodriguez-Luppi C, Martin AB, Trias M. Minimally invasive therapy for epiphrenic diverticula: systematic review of literature and report of six cases. J Minim Access Surg. 2014; 10: 169-74. 4. Soares R, Herbella FA, Prachand VN, Ferguson MK, Patti MG. Epiphrenic diverticulum of the esophagus. From pathophysiology to treatment. J Gastrointest Surg. 2010; 14: 2009-15. 5. Zaninotto G, Portale G, Costantini M, Zanatta L, Salvador R, Ruol A. Therapeutic strategies for epiphrenic diverticula: systematic review. World J Surg. 2011; 35: 1447-53. 6. Fernando HC, Luketich JD, Samphire J, Alvelo-Rivera M, Christie NA, Buenaventura PO et al. Minimally invasive operation for esophageal diverticula. Ann Thorac Surg. 2005; 80: 2076-80. 7. Herbella FA, Patti MG. Modern pathophysiology and treatment of esophageal diverticula. Langenbecks Arch Surg. 2012; 397: 29-35. 8. Herbella FA, Patti MG. Achalasia and epiphrenic diverticulum. World J Surg. 2015; 39: 1620-4. 9. Hirano Y,Takeuchi H, Oyama T,Saikawa Y,Niihara M, Sako H et al. Minimally invasive surgery for esophageal epiphrenic diverticulum: the results of 133 patients in 25 published series and our experience. Surg Today. 2013; 43:1-7. 10. Tapias LF, Morse CR, Mathisen DJ, Gaissert HA, Wright CD, Allan JS, Lanuti M. Surgical Management of Esophageal Epiphrenic Diverticula: A Transthoracic Approach Over Four Decades. Ann Thorac Surg. 2017; 104:1123-30. 11. D’Journo XB, Ferraro P, Martin J, Chen LQ, Duranceau A. Lower oesophageal sphincter dysfunction is part of the functional abnormality in epiphrenic diverticulum. Br J Surg. 2009; 96: 892-900. 12. Rossetti G, Fei L, del Genio G, Maffettone V, Brusciano L, Tolone S, et al. Epiphrenic diverticula mini-invasive surgery: a challenge for expert surgeons-personal experience and review of the literature. Scand J Surg. 2013; 102: 129-35. 13. FisichellaPM,JalilvandA,Dobrowolsky A.Achlasiaandepiphrenic diverticulum. World J Surg. 2015; 39: 1614-9. 14. Thomas ML, Anthony AA, Fosh BG, Finch JG, Maddern GJ. Oesophageal diverticula. Br J Surg. 2001; 88: 629-42. 15. Altorki NK, Sunagawa M, Skinnaer DB. Thoracic esophageal diverticula. Why is operation necessary? J Thorac Cardiovasc Surg. 1993; 10: 260-4. 16. Lai ST,Hsu CP.Carcinoma arising from an epiphrenic diverticulum: a frequently misdiagnosed disease. Ann Thorac Cardiovasc Surg. 2007; 13: 110-3. 17. Herbella FA, Del Grande JC. Benign esophagopulmonary fistula through an epiphrenic diverticulum and asymptomatic achalasia. Dig Dis Sci. 2010; 55:1177-8. 18. Vicentine FP, Herbella FA, Silva LC, Patti MG. High resolution manometry findings in patients with esophageal epiphrenic diverticula. Am Surg. 2011; 77: 1661-4. 19. Sato H, Takahashi K, Mizuno KI, Hashimoto S, Yokoyama J, Hasegawa G, Terai S. Esophageal motility disorders: new perspectives from high-resolution manometry and histopathology. J Gastroenterol. 2018; 53: 484-93.