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TRANSLATION.pdf

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Translation in prokaryotes
Translation in prokaryotes
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TRANSLATION.pdf

  1. 1. GROUP 3 Prepared By Agad
  2. 2. TRANSLATION OF m-RNA (PROTEIN SYNTHESIS) •Translation is the process that takes the information passed from DNA as messenger RNA and turns it into a series of amino acids bound together with peptide bonds. It is essentially a translation from one code (nucleotide sequence) to another code (amino acid sequence).
  3. 3. Steps of translation: • Step 1: Activation of amino acids This involzes attaching an amino acid to its respective transfer RNA (tRNA) forming the activated tRNA called aminoacyl tRNA. The key enzyme in this process is aminoacacyl-tRNA synthetase.
  4. 4. Steps of translation cont; • Step 2: Initiation In this step, activated tRNA attaches to the start codon (AUG) on mRNA, the small subunit of ribosome binds to mRNA and finally the large ribosomal subunit binds to form a initiation complex.
  5. 5. Steps of translation cont; • Step 3: Elongation Here according to codons found in the mRNA, the polypeptide chain keeps growing. Each amino acid is attached to the growing polypeptide chain by a peptide bond. Elongation continues till the whole gene is translated
  6. 6. Steps of translation cont; • STEP 4: Termination When the ribosome reaches the stop codon such as UAA, UAG or UGA, translation is finished since these codons lack tRNAs. When happens, translation is stopped and and a newly produced polypeptide chain is (protein) is released
  7. 7. THANKS FOR LISTSENING .

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