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Hormonal Regulations of
Metabolism
Glucagon
• Glucagon is secreted from α- cells of Pancreas
• 29 Amino Acids,
• Function of Glucagon is exact opposite of insulin (antagonist)
• Glucoagon is secreted when “GLUCOSE is GONE”
• “When Blood Glucose level is decreasing , Secretion of
glucagon will takes place
• HYPERGLYCEMIC HPORMONE”
ACTIONS OF GLUCAGON
• Physiological role of Glucagon is to stimulate
hepatic production and secretion of glucose
accomplishes by
 Glycogenolysis
 Increased Gluconeogenesis
– It exerts it effects on liver and adipose tissue
Role of Cortisol in Regulations of
Metabolism
• Cortisol is a steroid hormone
• Glucocorticoid class of hormones.
• Produced mainly in zona
fasciculata of the adrenal cortex in
the adrenal gland
hormones
hormones
hormones
hormones
hormones

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hormones

  • 2. Glucagon • Glucagon is secreted from α- cells of Pancreas • 29 Amino Acids, • Function of Glucagon is exact opposite of insulin (antagonist) • Glucoagon is secreted when “GLUCOSE is GONE” • “When Blood Glucose level is decreasing , Secretion of glucagon will takes place • HYPERGLYCEMIC HPORMONE”
  • 3. ACTIONS OF GLUCAGON • Physiological role of Glucagon is to stimulate hepatic production and secretion of glucose accomplishes by  Glycogenolysis  Increased Gluconeogenesis – It exerts it effects on liver and adipose tissue
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11. Role of Cortisol in Regulations of Metabolism
  • 12. • Cortisol is a steroid hormone • Glucocorticoid class of hormones. • Produced mainly in zona fasciculata of the adrenal cortex in the adrenal gland