Chronic Myeloid Leukaemia

CHRONIC MYELOID LEUKEMIA Dr.A.MEENAKSHI PROF.S.TITO’S UNIT. M4

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PERIPHERAL SMEAR PICTURE Band forms

Band forms promyelocyte myelocyte metamyelocyte

BONE MARROW PICTURE megakaryocyte

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BLAST CRISIS PHASE MYELOBLAST

Fluorescent insitu hybridisation

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Guidelines for response to imatinib treatment MMR CcyR noCcyR 18 CcyR McyR noMCYR 12 McyR mcyR No mcyR 6 CHR pHR NoHR 3 Optimal response Suboptimal response unsatisfactory Time of observation

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Chronic Myeloid Leukaemia

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Chronic Myeloid Leukaemia