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Presenting Scholar
Dr. Siba Prasad Rout
M.D(2nd Year)
Dravyaguna Department, IPGT & RA,
Gujarat Ayurved University,
Jamnagar- 361 008
Session:2014-2017
SìurÉÉhÉÉÇ lÉÉqÉÂmÉÉÍhÉ aÉÑhÉMüqÉÉïÍhÉ xÉuÉïzÉ:
mÉërÉÉåaɶÉÉÌmÉ uÉhrÉïliÉå rÉÎxqÉlÉ SìurÉaÉÑhÉÇ ÌWû iÉiÉ|| (P.V Sharma)
Dravyaguna shastra is the branch deals with the properties, action &
therapeutic effects of various dravyas.
Dravyaguna
. Vigyan
GUNAKARMA VIGYAN
(PharmacoDynamics)
Gunavigyan
(Pharmacology)
Karmavigyan
(Clinical
pharmacology)
Prayog vigyan
pharmacotherapeutics
Namarupavigyan
(pharmacognosy)
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ï
Ì¢ürÉiÉå AlÉålÉ CÌiÉ Ì¢ürÉÉ (Sì.aÉÑ.ÌuÉ)
The element which is responsible for the action of a drug is known as
‘’karma’’
Ì¢ürÉÉ sɤÉhÉÇ MüqÉï(lÉÉaÉÉeÉÑïlÉ)
The main property of karma is action.
In Ayurveda, drugs have been classified according to
pharmacological action. If comparative study is done on modes of
classification of drugs in Ayurveda and Allopathic, it can be concluded
that modern drug classification is similar to ancient one.
A. Drugs Acting On Digestive System
 Anulomna (Carminative)
 Arshoghna
 Atisarghna (Antidiarrhoeal)
 Kriminghna (Anthelmintic)
 Chhardinigrhana (Anti-emetics)
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B. Drugs Acting On Respiratory System
 Kaphanissaraka (Expectorant):Talishapatra (Taxus baccata)
 Kasahara (antitussive) :kantakari(solanum suratens)
 Mucolytic expectorant :Vasa(Adhatoda vasica)
 Swashara (bronchodialator): Dhatura(Dhatura metal)
C. Drugs Acting On Heart
Hridya (Cardiac tonics):Arjun(Terminalia arjuna)
 Shothghna (Anti-inflammatory): Dashamoola
D. Drugs Acting On Circulatory System
 Raktaprasadana (Alterative):Sariva(Hemidesmus indicus.) etc.
 Raktaskandana (Styptics):Nagakeshar (Messua fera)etc
E. Drugs Acting On Nervous System
 Nadi balya (Nervine):Ashwagandha (Withania somnifera) and Kapikachu (Mucuna
prurita),Bhallataka(Semicarpus anacardium) etc.
 Nidrajanana (Hypnotics):. Jatamansi (Nardostachys jatamansi) etc.
F. Drugs Acting On Kidney
 Ashamrighna (Lithontriptics):. Varuna (Cratevea nurvala) etc
 Mutrala (Diuretics):. Gokshura (Tribulus terresteris) and Punarnava
(Boerrhavia diffusa) are diuretics. They are used in treating edema.
 Mutrasangheneya:udumbar(ficus glomerata) etc
G: Miscellaneous Drugs_Rasayana, Vajikarana, Yakritautejjaka
(Choleretics) etc
:
 In this presentation, total 50 dravyas (Drugs) have been
reviewed vividly from all Nighantus (lexicons) and the
karma (clinical pharmacological) based paryaya
(synonyms) only have been assembled .
 Around 223 paryayas (synonyms )
 Traditional classical claims with evidence based
experiments have been summarized here in order to
correlate & justify its nomenclature
 At the end of presentation, dravyas have been categorized
systematically on the basis of their synonyms denoting to
their specific karmas .
Glimpses of Presentation
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L.N- Trachyspermum roxburghianum D.C
F.N: Umbelliferae
 Synonyms Based on Karma;
ÌSmrÉMüÉ(pÉÉ.mÉë) –It increases digestive fire.
Ì¢üÍqÉlÉÉÍzÉÌlÉ(Mæü.ÌlÉ)- Ì¢üÍqÉlÉ lÉÉzÉrÉiÉÏÌiÉ
kills the worms
Charak-
Deepaniya mahakashaya(ch.su4/9)
A.H.CHI14/35:
Hingwasthak churna-janayanti jatharagni .
. vatagulma cha nihanti
Vrinda madhav:Ajamodadi vati: Aamvat
अजमोदा
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Chemical Content:
Apioseglycosider,Apiin,Terpineol
T. ammi would increase the secretion of gastric acid; the addition
of T. ammi to the infusion increased the amount of gastric acid.
Gastric acid secretion was increased nearly four-fold by T. ammi.
In experimental rats in vivo, the addition of T. ammi to the diet
reduced food transit time and also enhanced the activity of digestive
enzymes and/or caused a higher secretion of bile acids.[48](Kohli
et all. 1964)
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AÌiÉuÉsÉÉ
 Latin Name: Abutilon indicum L.
 Family Name: Malvaceae
AÌiÉuÉsÉÉ(pÉÉ.mÉë):AiÉÏuÉ uÉsÉSÉlÉ MüUÉåÌiÉÌiÉ
ÌuÉëwrÉÉ (kÉ.ÌlÉ:): It is an effective Aphrodisiac.
uÉ××wrÉaÉÎlkÉMüÉ(UÉ.ÌlÉ):
uÉ×wrÉÉ zÉÑ¢üuÉÍkÉïÌlÉ,aÉÎlkÉMüÉ uÉåaÉeÉlÉÌlÉ,
aÉÎlkÉMüÉ uÉåaÉeÉlÉÌlÉ,uÉ×wrÉÉ cÉÉxÉÉæ aÉÎlkÉMüÉ cÉ. (UÉ.ÌlÉ)
Formulation:
Balaristha,Balataila(mɤrÉÉbÉÉiÉ-AlÉÑuÉÉxÉlÉ-xÉÑ.ÍcÉ.5/19).
Khirabalataila nasya(AÌSïiÉ-xÉÑ.ÍcÉ.5/22)
Charak:
Valya mahakashaya(ch su 4/18)
Vrimhaniya mahakashaya(ch su 4/28)
xÉÉaÉëÉÌWûMü uÉsrÉ uÉÉiÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/40)
Rasayan,vajikaran(ch.chi 1.2.12)
Shukra sruti vridhikar (Dalhan)
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Chemical Content
Ephedrin(sympathomimetic) steroids, triterpenoids, alkaloids,
saponins,flavonoids,
A)On Female Libido
Methanolic extract of areal parts of Abutilon indicum was investigated
for the libido enhancement activity at doses 100, 200 and 400 mg/kg
using automated runway methodology and copulatory behavior models.
The results revealed that the extract significantly improved the runway
parameters and copulatory behavior exhibiting its effectiveness in
enhancing the female libido1
B)As Immunomodulatory
In an experimental study the rasayana drugs namely
atibala.bala,mahabala,bhumibala, have been screened for their
immunonenhancing properties,Animals of drug treated group showed
statistically an enhanced properties of Anti S typhi O antibodies,Abutilon
indicumwasbestinaugmentingantibodyproduction.2
1) Effect of Abutilon indicum extract on FemaleLibido in Rats Khadabadi SS1* and Bhajipale NS2Kirtikar
K.R, Basu B.D;
2) IndianMedicinal Plants. Allahabad, India.1956, p. 314-316.
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AÌiÉÌuÉwÉÉ
 Latin Name: Aconitum heterophyllum(Wall.exRoyle)
 Family; Ranunculaceae
 AÌiÉxÉÉUÎblÉ(kÉ): AÌiÉxÉÉUqÉ lÉÉzÉrÉÌiÉ
 ÌmɨÉuÉssÉpÉÉ(kÉ): ÌmɨÉUÉåaÉåwÉÑ TüsÉmÉëSÉ
 zÉÉåTümÉWûÉ(kÉ.ÌlÉ):
 ÍzÉzÉÑpÉåzÉerÉÉ(xÉÉå):uÉÉsÉUÉåaÉåwÉÑ TüsÉmÉëSÉ
useful in child diseases.
AÉqÉÉÌiÉxÉÉU:
 AÉqÉÉÌiÉxÉÉUå:S±ÉiÉ xÉÉÌiÉÌuÉwÉÉqÉ mÉårÉÉqÉ xÉÉqÉå xÉqsÉÉqÉ
xÉlÉÉaÉUqÉ(cÉ.xÉÑ2/18)
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Formulation:
 Balachatrubhadra churna
Chemical: Atisenol,Heteratishin
Research
 In a clinical trial comprising 30 patients,Ativisha is found to be
effective in Atisara. the ant-diarrheal activity of roots of A. heterophyllum
may be attributed to an antisecretory and anti-enteropooling type effect
as a result of reactivation of Na + and K + ATPase activity mediated
through NO pathway. EAH causes either a decrease in mucosal secretion
or increase in mucosal absorption, which allows the feces to become desic
cated thus retarding its movement through the colon. The above activity
was well supported with a potential antibacterial activity. Thus, the
present study justifies the use of roots of A. heterophyllum in treatment of
diarrhea.
Antisecretory and antimotility activity of Aconitum heterophyllum and its significance in treatment of
. diarrhea
 Siva Hemalatha, Divya Jain, Dinesh K Patel, Satyendra K Prasad,Alakh N SahuIndian Journal of Pharmacology,Vol. 46, No. 1,
January-February, 2014, pp. 82-87
मधुनाऽतिविषाश्रृङ्गीविप्िलीलेहयेच्छिशुम ् ।
एकाां िाऽतिविषाां कासज्िरछिर्दिभिरर्दििम ् ।।
(अ.हृ.उ.2.57)
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AeÉÑïlÉ
 Latin Name: Terminalia arjuna
 Family Name:Combretaceae
 ™SìÉåaÉuÉåËU(Sa)
 µxÉlÉåxuÉU(K.N)
AeÉÑïlÉxrÉ iuÉcÉÉ ÍxÉkÉqÉ ¤ÏUqÉ rÉÉåerÉqÉ ¾èSÉqÉrÉå
ÍxÉiÉrÉÉ mÉlcÉqÉÑsrÉÉ uÉÉ oÉsÉrÉÉ qÉkÉÑMåülÉ uÉÉ (ÌuÉë.qÉÉ)
 Milk processed withsarkara,panchamula,bala, and madhuka should
be used in cardiac disorders.
cÉÑlÉïqÉ MüMÑüxiÉoÉqÉÏxjÉqÉ uÉxÉ¢üxÉqÉ pÉÌoÉiÉqÉ uÉÉWÒûuÉÉUqÉ
bÉëÏiqÉkÉÑÍxÉiÉÉåmÉsÉqÉ sÉåWûqÉ ¤rÉxuÉÉzÉMüÉxÉÌmÉiÉWûUqÉ
(pÉÉ.mÉë UeÉrZqÉÉ ÍcÉ 12/29)
Powdered Arjun bark impregnated with vasa juice several times should be
taken with ghee honey sugarcandy.it alleviates cough,swasa,pitta etc.
 Chemical content
 Arjunic acid,Tannins,Arjunolic acid drrout.sibaprasad@gmail.com,24/06/2016
Friday
 The present study demonstrated prophylactic and
therapeutic potential of Terminalia arjuna bark extract in
isoproterenol (ISO)-induced chronic heart failure (CHF).
Fifteen days after injection of ISO (85 mg/kg twice at an
interval of 24 h, s.c), rats showed fall of left ventricular
pressure, cardiac contractility index (LV (dP/dt)max/LVP),
and rise in cardiac output ,LV end-diastolic pressure. CHF
rats showed a significant increase in serum creatine kinase
isoenzyme-MB (CK-MB) increased level of cytokine tumour
necrosis factor-α (TNF-α) along with histological changes in
heart were also observed in CHF rats. . Cardioprotective
action of T. arjuna was comparable to fluvastatin, a synthetic
drug. The results suggest that T. arjuna bark extract has a
significant prophylactic and therapeutic beneficial effect on
protection of heart against ISO-induced CHF possibly
through maintaining endogenous antioxidant enzyme
activities, inhibiting lipid peroxidation and cytokine levels.
 mÉ
Mechanistic Clues in the Cardioprotective Effect of Terminalia Arjuna Bark Extract in Isoproterenol-Induced . . .
. Chronic Heart . . . Failure in Rats
 Adila Parveen, Rashmi BabbarSarita AgarwalAnita Kotwani Mohammad Fahim
 mÉÉjÉï ¤ iÉå AÌlÉsÉå pÉalÉå U£üxiÉqpÉå oÉsÉåÌWûiÉ(zÉÉå.ÌlÉ)drrout.sibaprasad@gmail.com,24/06/2016
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AzÉÉåMü
Latin Name_Saraca ashoka
Family Name-Caesalpinacea
 xiÉUÏÌmÉërÉ: used in all gynaecological disorders
 AzÉÉåMü:lÉ zÉÉåMüÉxqÉÉiÉ
 xqÉUÉÍkÉuÉÉxÉ: xqÉU xqÉëÑÌiÉ iÉzrÉ AÍkÉuÉÉxÉ
Chemical content:
arjunic acid,fredelin,tannin
अशोकवल्कलक्वाथश्रृतं दुग्धं सुशीतल्
यथाबलं पिबेत प्रातस्तीव्रासृग्दरनाशन् . ,
(वृ.्ा.63.5)
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Research
 Oxytocic activity of the plant was seen in rat and
human isolated uterine preparations. Estrogen-primed or
gravid uterus was more sensitive to the action of the
alcoholic extract. The bark of Saraca ashoka, which is the
real potent drug, is reported to have a stimulating effect
on the endometrium and ovarian tissue tonic contraction
and is therefore very valuable in treating problems like
menorrhagia due to uterine fibroids, in leucorrhea and in
internal bleeding. Ashoka or Saraca indica is helpful in all
cases of uterine bleeding.(B.N GHOSH,PMMT)
 (http:// www. da-academy org/dagardenssaraca1.html. )
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Anti convulsant activity of methanolic extract of leaf of
Saraca indica Linn shows that it could have blocked the
seizure spread by inhibiting Na+ channels and glutamatergic
excitation through NMDA enhancement of GABA activity
[26]. Hence from the results indicated the presence of
anxiolytic activity inthe Saraca indica Linn. leaf extract by act
through potentiating the GABA inhibition in the CNS as that
of standard drug diazepam.
Neuropharmacological Screening of Saraca Indica leaves
 Talever Singh*, Snigdha Gupta, Milind Pande, Mrs Akansha Singh Guru Drone Journal of Pharmacy and
Research. 2014; 2(2): 30 -37
S. Ashoka extracts typically relieve pain by acting on
both the central and peripheral nervous systems
Experimental evaluation of analgesic property of bark skin of Saraca
indica (Ashoka) and Shorea robusta (Shal)
Poonam S. Mohod1, C. R. Jangde2, S. D. Narnaware3, Subhash Raut4
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AµÉaÉlkÉÉ
 Latin name:Withania somnifera Dunal
 Family Name:Solanacea
 mÉѧÉSÉ(ÌlÉ.AÉ):mÉѧÉÇ SSÉÌiÉ zÉÑ¢üuÉkÉïlÉÉjÉï
 ÇqÉÉÂiÉÎblÉ(xÉÉå)
 MüÉqÉÂÌmÉÍhÉ(UÉ.ÌlÉ):
 MüÉqÉxrÉ ÂmÉÇ pÉuÉirÉxrÉuÉÉ
It promotes complexion
 uÉsrÉÉ(kÉ.ÌllÉ),ÌuÉëwrÉÉ(Måü.ÌlÉ)
Vajikaran(pÉÉ.mÉë)
Shukrala:(zÉÉ)
cÉUMü
Valya,vrihmaniya
Alepan in Rajyakhma
(ch.chi 8/77)
अश्िगन्धाकषायेण कलकक ैः क्षीरां चिुगुिणम ् ।
घृिां िक्िां िु िािघ्नां िृष्यां माांसवििधिनम ् ।। (िृ.मा.22.73)
Vatavyadhi;
Ashwagandha kashaya with four times ghee and milk
pacifies the vata
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Rasayan-One who takes the powder of aswagandha root in
late winter mixed with honey & ghee along with milk
regains the youthfulness.
Sedative effect:
In a very high dose, it may have sedative effect.
Hence some experts advice to avoid it during day
िीताऽश्वगन्धा ियसाऽधध्ासं घृतेनं तैलेन सुखाा्बुना वा
कृ शस्य िुपटं विुषो पवधत्ते बालस्य सस्यस्य यथा सुवृपटिः 
(अ.हृ.उ.39.158)
Chemical:
Withanol:Aphrodisiac
Enhygriene: Lowering B.P
Somniferin:Sedative Effect
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 It enhances the function of the brain and nervous system and improves
the memory.
 It improves the function of the reproductive system promoting a healthy
sexual and reproductive balance.
 Being a powerful adaptogen, it enhances the body’s resilience to stress.
Ashwagandha improves the body’s defense against disease by improving
the cell-mediated
 immunity. It also possesses potent antioxidant properties that help
protect against cellular damage caused by free radicals
 Withania somnifera treatment prevents, decrease of adrenal cortisol and
ascorbic acid.
 Ashwagandha given to a group of mice with milk injection produced
reduction in leucocytosis.
 Anabolic effects:
 Cognition Promoting Effect
 roots of Ashwagandha
 significantly reversed ibotenic acid induced cognitive defects in
Alzheimer’s disease model (Bhattacharya et al., 1995)
 Anxiolytic effect
 Singh et al., Afr J Tradit Complement Altern Med. (2011) 8(S):208-213 208
 AN OVERVIEW ON ASHWAGANDHA: A RASAYANA (REJUVENATOR) OF AYURVEDA
 Narendra Singh#, Mohit Bhalla, Prashanti de Jager* and Marilena Gilca**
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असनैः (बीजकैः)
 Latin Name: Pterocarpus marsupium Roxb.
 Family name: Fabaceae
 MüÉzrÉï: it causes emaciation.
Sesamum oil in the morning with decoction of heartwood . .
of asana mixed with honey effective in sthaulya.
अपतस्थूलशरीरो यपस्तलतैलं mÉëÉगे पिबेत
पिबेदसनसारस्य क्वाथं वा ्धुसंयुत् (वै.्.12.30)
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अच्थिसांहारैः
Latin name:Cissus quadrangularis Linn
Family name:Vitaceae
AÎxiÉxÉÇrÉÉåeÉMü:(pÉÉ.mÉë):AÎxiÉÌlÉ pÉalÉxÉÇWûÉUrÉÌiÉ rÉÉåeÉrÉÌiÉ CÌiÉ
Cures fractures, dislocation and causes reunion in fractures.
सघृिेनाच्थिसांहारां लाक्षाां गोधूममजुिनम ् ।
सच्न्धमुक्िेऽच्थििग्ने च विबेि् क्षीरेण मानिैः । (िृ.मा.46.8)
One should take the combination of asthisamhara, lac,wheat
flour,Arjun with milk added with ghee in case of dislocation of joints and
bone fracture.
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Research
 The anabolic steroids from Cissus quadrangularis
showed marked influence in the rate of fracture healing by
influencing early regeneration of all connective tissues
involved in the healing and quicker mineralization of callus.1
 Systemic use of Cissus quadrangularis restores fracture in
four weeks in trial group while the controls required six
weeks. That is due to increase in mucopolysaccharides
level,proliferation of osteoblastic, chondroblastic and cartilage
proliferation, increased mineralization in the callus. Thus the
parenteral administration of the total extract of Cissus
quadrangularis not only neutralized the anti-anabolic effect of
cortisone in healing of fractures but also enhances the
mineralization of the callus possibly due to its vitamin
contents.2
 Udupa K.N., and Prasad G., Biochemical and studies on the effect of cissus quadrangularis in fracture repair, lndian J. Med.
 Res., 1964, 52, (5) 480-487.Udupa K. N., and Prasad G. C., Further studies on the effect of Cissus quadrangularis in acceleratingGarima Mishra
et al /Int.J. PharmTech Res.2010,2(2) 1308 fracture healing, Indian J. Med. Res., 1964, 52,
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आमलकी
 Latin Name_Emblica officinalis Gaertn
 Family :Euphorbiacea
 AqÉëÑiÉÉ(ÌlÉ.AÉ):lÉ ÍqÉërÉiÉå AlÉrÉÉ CÌiÉ
If it is consumed,no untimely death
 AÉqÉsÉÌMü(ÌlÉ.AÉ):AÉ xÉqÉÉliÉÉiÉ qÉsÉiÉå kÉÉUrÉÌiÉ
UxÉÉrÉlÉaÉÑhÉÉlÉ CÌiÉ(full of rasayan properties)
 uÉrÉxiÉÉ(pÉÉ.mÉë)
ÌuÉëwrÉÉ(pÉÉ.mÉë)
 Chemical Content
 Hydrolyzable tannins
 Emblicanin A,B
 Ellagic acid(inhibits the mutation of genes and reduce
chromosomal abnormalities.
AÉqÉsÉMüÐ uÉrÉxiÉÉmÉlÉÉÇ(cÉ.xÉÑ25/40)
ÌlÉirÉ xÉåuÉÌlÉrÉ SìurÉ(cÉ.xÉÑ 5/12)
AÉqÉsÉMüÐ cÉÑhÉï:uÉwÉïzÉiÉqÉ AeÉUÇ(cÉ.ÍcÉ1/1/8)
U£üÌmÉ¨É mÉëqÉåWûblÉ mÉUÇ ÌuÉëwrÉ UxÉÉrÉlÉ (pÉÉ.mÉë)
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Research

 The fruits extracts of Emblica officinalis (Amla) has
been reported to have strong anti-oxidant properties..
Chromium (Cr), an immunosuppressive agent results in
enhanced cytotoxicity, free radical production, lipid
peroxidation and decreased glutathione peroxidase (GPx)
activity and diminished glutathione (GSH) levels. There was a
significant inhibition concanavalin-A-stimulated lymphocyte
proliferation. Chromium also inhibited Con A .Amla
significantly inhibited Cr-induced free radical production and
restored the anti-oxidant status back to control level. Amla
also inhibited apoptosis and DNA fragmentation induced by Cr.
Interestingly, Amla relieved the immunosuppressive effects of
Cr on lymphocyte proliferation and even restored the IL-2 and
γ-IFN production considerably.
Ram, M. Sai, et al. "Cyto-protective and immunomodulating properties of Amla (Emblica officinalis) on lymphocytes: an
. in-vitro study." Journal of Ethnopharmacology 81.1 (2002): 5-10.
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आरग्िधैः
L.N: Cassia fistula Linn
Family:Leguminoseae
AÉUauÉkÉ(ÌlÉ.AÉ);AÉUaÇ UÉåaÉxÉÇMüÉqÉÌmÉ WûÎliÉ
it eliminates the diseases with mere doubt
AÉUuÉåiÉ- AÉ UåuÉrÉÌiÉ ÌlÉÈxÉÉUrÉÌiÉ qÉsÉqÉ xÉÉUYiuÉÉiÉ.
It acts as laxative.
MÑü¸xÉÑSèlÉ(Ra.Ni), euÉUÉliÉMü(sodhal)
AÉqÉWûÉ(shodhal), urÉÉÍkÉbÉÉiÉ(K.N)
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 आरग्िधे िा ियसा मृद्िीकानाां रसेन िा।
त्रििृिाां िायमाणाां िा ियसा ज्िररिैः विबेि् ।।
(च.चच. 3.232)
Aragwadha with milk and grape juice alleviates jwar.
आरग्िधथय ििाणण आरनालेन िेषयेि् ।
दद्रुककर्ििकु ष्ठातन हच्न्ि भसध्मानमेि च ।।
(बां.से.कु ष्ठ.63)
Leaves of aragwadha pounded with sour gruel and applied
on the part of ring worm,kitibha,kustha,sidhma .
आरग्िधथय ििाणण िृष्िातन किुिकलिैः ।
आमघ्नातन नरैः कु यािि ् सायां िक्िािृिातन च ।।
(िा.प्र.चच.26.52)
Leaves of aragvadha fried with mustard oil and taken in
evening followed by meal.It alleviates ama.
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research The plant contains more or less same
components such as saponin,
triterpenoids, steroids, glycosides,
anthraquinone, flavonoids, gum,
mucilage, proteins and aminoacids.
From the above results, the activity of
hydroalcoholic extracts of C. fistula
shows significant antibacterial and
antifungal activity. The chloroform
extracts, whose purity level is good as
compared to hydroalcoholic extract
and porosity is lower than
hydroalcoholic extract, found to be
more active against fungal strains.
Results shows that this plant is rich in
tannin and phenolic compounds have
been shown to possess antimicrobial
activities against a number of
microorganisms.
In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
N. R. Bhalodia, P. B. Nariya,1 R. N.Acharya,2 andV. J. Shukla3
drrout.sibaprasad@gmail.com,24/06/2016
Friday
इङ्गदी
Latin name:Balanites aegyptica L.Delie
Family:Simarubaceae
ChaÉÑÌS(Ni.Adrsha):
CaÉqÉ MÑü¸pÉÑiÉaÉëWûÉÌSlÉÉzlÉqÉ
It removes the dosas and cures conditions like kustha
ÌuÉwÉÎblÉ(sodhal):Antipoisonous
 MüÉzrÉmÉ-ÍzÉzrÉÉåmÉlÉrÉlÉ xÉÇxMüÉU
xÉÑ´ÉÑiÉ-UÉåqÉxÉÉiÉlÉ(xÉÑ.ÍcÉ1/108)
cÉUMü-mÉëxÉÑiÉÉaÉëÑëWû(cÉ.zÉÉ8/34)
कु ष्ठेषु हितान्यािुChaÉÑÌSस्तैलम् (च.हच.7.119)
मूवषकविषे
भशरीषेङ्गदकलकन्िु भलह्यात्ति समाक्षक्षकम ् । (सु.क.7.12)
Ingudi fruit kalka with shirish and honey useful in Rat
poisoning. drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
Alcoholic extracts fruit of B. aegyptiaca have remarkable
antimicrobial potential and thus can be used to derive
antimicrobial agents especially against S. aureus, E. coli,S.
typhi and S. paratyphi A. Hence, it can be used in the
treatment of enteric fever, diarrhea, wound infections and
urinary tract infections.
drrout.sibaprasad@gmail.com,24/06/2016
Friday
इन्द्रिारुणी
Latin name:Citrullus colocynthesis Linn
Family name: Cucurbitaceae
ClSìèuÉÉÂÍhÉ:ClSìÉ zÉÌ£üxÉqmÉlÉÉï uÉÉÂÍhÉ eÉsÉUåcÉÌlÉ.
ÌuÉzÉÉsÉÉ(ÌlÉ.AÉ):
ÌuÉzÉåwÉåhÉ zsÉÌiÉ- cÉsÉÌiÉ MüÉqÉsÉÉÌSUÉåaÉiÉÌlÉuÉUÉÌrÉiÉÑ
It spreads all over body to cure the conditions like jaundice
etc.
ÌuÉwÉÎblÉ:(xÉÉå):ÌuÉwÉqÉ WûÎliÉ
र्हिा गिाक्षी सगुडा च शुण्ठी (सु.उ.44.30)
Indravaruni mixed with jaggery & shunthi useful in kamala.
ccc
cÉUMü
qÉÑÍsÉÌlÉ(xÉÑ/1/77,ÌuÉUåcÉlÉ(xÉÑ/2/9)
xÉÑ´ÉÑiÉ
AkÉÉåuÉÉaÉWûU(xÉÑ.xÉÑ.39/4)
Colocynthin acts as
gastrointenstinal
irritant,produces abdominal
pain,watery stool
drrout.sibaprasad@gmail.com,24/06/2016
Friday
ESÒqoÉU
Latin Name: Ficus glomerata Roxb.
 Family Name:Moracea
 ESÒqoÉU(pÉÉ.mÉë):
ESÒqoÉsÉ mÉë¢Ñü¹oÉsÉMüU CirÉijÉï
The ripe fruit eaten promotes strength to body.
 qÉsÉrÉÑ:(ÌlÉ.AÉ): qÉsÉqÉ ÍµÉ§ÉqÉ ÌlÉWûÎliÉ.(It cures leucoderma.).
 (Kakudumbar:ficus hispida)
1st Brahmarasayan
Patra-udumbar
(ch.chi1/1/57)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
एरण्डैः
Latin Name:Ricinus communis Linn
Family:Euphorbiacea
LUhQû:(pÉÉ.mÉë): LUrÉÌiÉ uÉÉrÉÑqÉ CÌiÉ
uÉÉiÉÉËU (R.N);uÉÉiÉxrÉ AËU zɧÉÑ lÉÉzÉMüÉå CÌiÉï
zÉÑsÉzɧÉÑ:(Sa.Ni)
cÉUMü:uÉëÑwrÉuÉÉiÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/0)
xÉÑ´ÉÑiÉ:AkÉÉåuÉÉaÉWûU(xÉÑ.xÉÑ.39/4)
U.U.xÉ/pÉÉ.mÉë:AÉqÉuÉÉiÉ
P.V Sharma_vedanasthapan LUhQû zÉÉåTüzÉÑsÉblÉ ÌuÉëwrÉ uÉÉiÉWûUÇ mÉUÇ(UÉ.ÌlÉ)
The mechanism of analgesic effect of ricinolic acid could probably be
due to inhibition of the effect of endogenous substances
that induces pain at nerve endings similar to that of NSAIDs.
r,
1,*
ÌuÉश्व्ेरण्डजं ्ूलं क्वाथपयत्वा जलं पिबेत
प ंगुसौवर्धलोिेतं सद्यिः  शूलपनवारण् (भा.प्र.पर्.30.57)
One should take decoction of shunthi,root of errand,
hingu & rock salt, gets instant colic relief
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
Central analgesic activity:
The crude extract of root bark of R. communis possesses central
analgesic activity in tail flick response model to radiant heat at a dose of
250mg/kg. The ethanolic extract of pericarp of root bark of R. communis
possesses typical CNS stimulant and neuroleptic effects. The stimulant
effects, such a exophthamus, hyperreactivity (evidenced by tremors or by
the pinna and grip-strength reaction), memory improvement and clonic
seizures, seem to be due to the presence of the alkaloid ricinine. On the other
hand,compounds other than ricinine may be responsible for the neuroleptic-
like effects of the extract,because ricinine did not cause reduction of
locomotor activity or catalepsy in the mice.
Ferraz A.C., Angelucci M.E.M., Da Costa M.L., Batista I. R., De Oliveira B.H. and Da Cunha C. Pharmacological Evaluation of
Ricinine, a Central Nervous System Stimulant Isolated from Ricinus communis. Pharmacology Biochemistry and Behavior1999; Vol.
63: No. 3: 367–375.
drrout.sibaprasad@gmail.com,24/06/2016
Friday
MüOÒûMüÉ
 L.N: Pichrohiza Kurroa Royle ex. Benth
F.N- SCROPHULARACEAE
 MüOÒûMüÉ(pÉÉ.) MüOûÌiÉ UÉåaÉqÉ ÌuÉëhÉÉÌiÉ CÌiÉ
It engulfs the diseases.
 AËU¹(kÉ.ÌlÉ):lÉ ËU¹qÉÉzÉÑpÉxrÉ
 AÉqÉÎblÉ(kÉ.ÌlÉ) it pacifies the ama.
अम्लवित्ते
 किुकाभसिा ऽिलेह्या ििोलविश्िां च क्षौद्रसांयुक्िम ्(िृ.मा.53.14)
ÌlÉrÉÌiÉ MüÉÍsÉMü euÉU-pÉÉ.ÌlÉ
वित्तज्िरघ्नी किुका श्र्लेक्ष्णविष्िा सशकि रा । (अ.सां.चच. 1.76)
cÉ
cÉUMü:sÉåZÉÌlÉrÉ,pÉåSÌlÉrÉ
xÉÑ´ÉÑiÉ:qÉÑxiÉÉÌS,mÉOûÉåsÉÉÌS-AÉqÉÌiÉxÉÉUlÉÉzÉlÉqÉ
ÌuÉzÉåwÉÉiÉ SÉåwÉmÉÉcÉlÉ
ÌmÉë.zÉ-ÌmɨÉÌuÉUåcÉMü
M.C of Arogyvardhini
Total use-28 diseases(B.R)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
Iridoid glycosides like kutkin, Picroliv, Picrisides I, II, III&IV,Kutkosides
are the chemical moieties that may be responsible for
Antipyreticactivity.
Ghisalberti E.L, Biological and Pharmacological activity of naturallyoccurring Iridoids and Secoiridoids,Phytomedicine 5, 147-163, 1998.drrout.sibaprasad@gmail.com,24/06/2016
Friday
MühOèMüÉËU
 Latin name-Solannum surattens Burm f
 Family:Solanacea
 MüÉxÉÎblÉ(pÉÉ.)
 SìÉuÉÍhÉ:(A.ÌlÉ) zsÉåwqÉÉhÉÉqÉ SìÉuÉrÉÌiÉ
 (MüTü ÌlÉxÉÑSlÉqÉ xÉÑ.xÉÑ,38)
 urÉÉÍbÉ((pÉÉ.)ë:urÉÉÎeÉbÉëÌiÉ aÉlkaÉëWûhÉqÉ MüUÉåÌiÉ
 It improves olfactory function
(Bapal Vaidya)
ÌlÉÌSÎakÉMüÉ(ÌlÉ.AÉ)-ÌlÉiÉUÉqÉ ÌS½iÉåxqÉ,EwlÉiuÉÉÌS aÉÑhÉå CÌiÉ
Owing to its ushna tikshna ,it spreads
all ovder body easily,alleviates diseases.
Major chemical constitutes:
BCarotene,Disgenin,
Solanocarpine(Solanine-S), Tomatidienol etc.
Charaka
Kasahara Hikkanigrahana
Kanthya
A.H:MüÉxÉåÌlÉÌSÎakÉMüÉ(A.¾û.E )
ÌmÉë.ÌlÉ-MüÉxÉWûU
िीनसे ;व्याघ्रीतैल् (शा.सं.2.9.180)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Gautam et al. 2008 studied effects of Solanum xanthocarpum extract on some of
the parameters like smooth muscle relaxation, and antagonism of asthma mediators
such as histamine, eiosinophils and protection against mast cell degranulation which
seemed to be prominent in pathophysiology of asthma. Further they showed that
ethanol extract of Solanum xanthocarpum shown a significant antihistaminic activity
in histamine induced contractionin goat tracheal chain preparation.Thus, the
significant inhibition of histamine induced contractions produced by ethanol extract
of Solanum xanthocarpum flower on isolated goat tracheal chain preparation indicates
that the Solanum xanthocarpum flower has antihistaminic (H1- receptor antagonist)
action.While screening the all three extracts of flowers of Solanum xanthocarpum,
results were indicative that only ethanolic extract of Solanum xanthocarpum at a dose
of 50 and 100 mg / kg reduced milkinduced eiosinophilia of statistical significance.
Solanum xanthocarpum at a dose of (50- 100 mg/kg, i.p) showed significant mast cell
stabilization as compared to standard drug
Disodiumchromoglycate (DSCG).
Vadnere GP, Gaud RS, Singhai AK; Evaluation of Anti-Asthmatic Property of Solanum Xanthocarpum Flower Extracts. Pharmacology
online, 2008; 1: 513-522.
कण्टकारीरसे पसद्धो ्ुद्गयूषिः  सुसंस्कृ तिः 
सगौरा्लकिः  सा्लिः  सवधकासपभषपग्जत् (र्.पर्. 18.184)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
MüÌmÉMücNÒûBotanical name: Mucuna pruriens Hook.
Family: Fabaceae
 MühQÒûUÉ(pÉÉ.)
 ÌuÉëwÍpÉ((pÉÉ.)
 ÌuÉëzrÉÌuÉeÉÉ(kÉ.ÌlÉ)
Charak;Valya mahakashya(ch.su 4/7)
Vrihmani gutika,apatyakar swaras-vajikara(ch.chi)
Amritprasghreet,2nd sarpiguda-kshatkhina(ch.chi 11
Sarangdhar:Vajikar dravya
Mucuna Pruriens L Dopa crosses BBB,decarboxylated
& converted into Dopamine.
L-Dopa
DOPAMINE INHIBITS PROLACTIN AND PRESERVES TESTOSTERONE
Deficiency of L
Methyl Dopa causes
Parkinsonism.
Kapikachu D.O.C IN
Parkinsonism
% of L-DOPA at
Velvet Bean
Outer Pericarp:3-6%
Endocarp:5.3%
ADR
GastricUpset,Breathlessn
es,Insomnia,Headache,
Local irritation
drrout.sibaprasad@gmail.com,24/06/2016
Friday
 Methanolic extract of Mucuna pruriens seed was
tested for their possible androgenic activity in
Wistermale albino rats. The methanolic extract of
M. pruriens plant was gavaged separately into 2
group of ratat similar doses of 1000 mg/kg b.wt and
1500 mg/kg b.wt for 30 days. At the end of the
treatment, the animals were killed and the blood,
testis, epididymis, seminal vesicles and prostate
were collected for biochemical analysis. The
methanolic extracts of M. pruriens significantly
increased the relative weight of the testis, serum
and testicular testosterone level, protein level in
the testis and epididymis, and epididymal alkaline
phosphatase activity. The methanolic extracts of
M.pruriens possess androgenic activity.
Evaluation of androgenic activity of Mucuna pruriens in male rats
K. Muthu1* and P. Krishnamoorthy2
वानरी वपटका (भा.प्र.पर्.72.71-75)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
MüÎqmÉssÉMü
 UåcÉlÉ(pÉÉ.mÉë)
 U£üzÉqÉlÉ(Måü.ÌlÉ)
 UÉåcÉlÉMü(Måü.ÌlÉ)
 uÉëhzÉÉåkÉlÉ(Måü.ÌlÉ)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Ethanolic extract of Mallotus philippinensis fruit
(200 mg/kg) was administered orally, once daily for
10 days .MPE was found safe when given to rats upto
10 times of optimal effective dose. Mallotus
philippinensis has been tested in-vitro for wound
healing activity by examining the proliferation,
migration of mesenchymal stem cell by secreting
various cytokines to wounded site from bone
marrow to systemic circulation and finally remodel
wounded tissues
Mallotus philippinensis Muell. Arg fruit glandular hairs extract promotes wound healing on different wound model in rats
BMC Complementary and Alternative Medicine Sampledoi:10.1186/s12
drrout.sibaprasad@gmail.com,24/06/2016
Friday
MÑÇüMÑüqÉ
 L.N:Crocus Sativus Linn
 F.N:Iridaceae
 MÑÇüMÑüqÉ:MÑüYrÉiÉå AÉÌSrÉiÉå ÍzÉUÉåÂaÉ uÉëhÉÌSlÉÉzÉlÉjÉï
 It is used in headache,wound etc.(ni.adarsh)
 uÉhrÉïqÉ(pÉÉ.mÉë)
Excess intake of saffron at
pregnancy might cause
contraction of uterus leading to
possible miscarriage.
Headache,Anxiety,Skin
allergies,Dryness of mouth
Stomach upset if saffron taken
more.
शकध राकु ङक्श्रृतं घृतं पित्तासृगन्वये (अ.हृ.उ.24.7)
Headache caused due to pitta=rakta to be aleeviated with
intake of snuff of ghee cooked with sarkara and kumkuma
drrout.sibaprasad@gmail.com,24/06/2016
Friday
MÑüOûeÉ
zÉ¢ü:zÉYlÉÉåÌiÉ CÌiÉ AÌiÉxÉUÉÌS UÉåaÉÉlÉ
(ÌlÉ.AÉ)
xÉlaÉëÉÌWû:mÉÑËUwÉqÉ xÉlaÉëÉëWûÌiÉ
mÉÑÇMÑüOûeÉ Îx§ÉMÑüOûeÉ
(H.antidysenterica) (Wrightia tomentosa)
ÌuÉëWûiÉ TüsÉ zrÉÉqÉ
µÉåiÉmÉÑwmÉ TüsÉÌuÉëliÉ AhÉÑ
ÎxlÉakÉmÉ§É AÂhÉmÉÑwmÉ
ÌiÉ£ü UxÉ qÉkÉÑU
Acharya Dalhan strictly opines that pum kutaj to be used in the
management of Atisara(Diarrhoea)
Charak
Arshoghna,Kandughna
MÑüOûeÉiuÉMü
zsÉåwqÉÌmÉiÉU£üxÉÉÇaÉëÉÌWûMüÉåmÉzÉÉåwÉÉhÉÉqÉ
(cÉ.xÉÑ25/40)
Isolated use of Kurchicine as antidiarrhoel is not safe as Kutajghanvati in atisaradrrout.sibaprasad@gmail.com,24/06/2016
Friday
H. antidysenterica produces gastrointestinal tract
stimulation by activation of histamine receptors and
relaxes the gastrointestinal tract by Ca++ channel
blockade, which provided the basic ground for its
usefulness in gut motility problems such as
constipation, colic and diarrhea [8]. The alkaloid
conessin posseses Ach inhibitory activity and act as
antidiarrhoeal.
The present study concludes that ethanolic extract
of H. antidysenterica seeds is effective against
noninfectious as well as infectious diarrhea as it
possesses antimicrobial and antidiarrheal property.
Evaluation of antidiarrheal activity of ethanolic extract of Holarrhena antidysenterica seeds in rats
Dushyant Kumar Sharma, Vinod Kumar Gupta, Surendra Kumar, Vet World. 2015 Dec; 8(12): 1392–1395drrout.sibaprasad@gmail.com,24/06/2016
Friday
MüÉåÌMüsÉɤÉ
 L.N:Asteracantha longifolia
 F.N:Amaranthaceae
 AkrhQû
 msÉÏWûzɧÉÑ(ÌlÉ.AÉ)
 CZÉÑU uÉÉiÉU£üÉqÉuÉÉiÉÎeÉiÉ zÉÑ¢üuÉkÉïlÉ (zÉÉå.ÌlÉ)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
वातरक्ते
कोपकलाक्षा्ृताक्वाथे पिबेत कृ षणां यथाबल्
िथ्यबोजी पिसप्ता ान ्ुच्यते वातशोपणतात (र्.द.39.23)
वाजीकरणे
स्वयंगुप्तेक्षुरकयोिः  फलर्ूणं सशकध र्
धारोषणेन नरिः  िीत्वा ियसा न क्षयं व्रजेत
(सु.पर्.26.33)
cÉUMü
zÉÑ¢üzÉÉåkÉlÉ,qÉkÉÑUxMülS
xÉÑ´ÉÑiÉ
uÉÉÎeÉMüU(xÉÑ.ÍcÉ.26/38)
Research:
 The ethanolic extract of seeds of A. longifolia was
administered to groups of rats in 100, 150 and 200 mg
kg⁻¹ doses for a period of 28 days, and the action
compared with control rats. The ethanolic extract
exhibited pronounced anabolic effects in treated animals,
as evidenced by gains in the body and reproductive organ
weights. Increased spermatogenesis due to treatment with
extracts was also witnessed in transverse section. The
treatment further markedly affected sexual behaviour of
the animals, as reflected by the reduction of ML, increase
in MF and enhanced attractability towards females. A
significant increase in the sperm count as well as fructose
levels of seminal vesicles was noted.

Effect of Asteracantha longifolia seeds on the sexual behaviour of male rats.
Chauhan NS1, Sharma V, Dixit VKNat Prod Res. 2011 Sep;25(15):1423-31. doi: 10.1080/14786410802588493. Epub 2011
Jul 8.
drrout.sibaprasad@gmail.com,24/06/2016
Friday
ZÉÌSU
 L.N:Acacia catechu
 F.N:Mimosaceae
 MÑüwPèblÉ(pÉÉ.)
 aÉsÉUÉåaÉÌlÉëiÉ(xÉÉå)
 SliÉkÉÉuÉlÉ(pÉÉ)
 qÉåSÉåblÉ(xÉÉå)
 uÉëhzÉÉåkÉlÉ(UÉ.ÌlÉ)
व्रणशोधने(cÉ.ÍcÉ.25/84)
त्रिफला खर्दरो दािी न्यग्रोधार्दबिला कु शैः। (च.चच.199-206)
तनम्बकोलकििाणण कषायाैः शोधनाैः मिाैः । मुखरोगे;खदिरादिगुडिका,
Heartwood is used to yield concentrated aqueous extract i.e. Cutch
and Katha. The cutch and Katha (extract) possess astringent, cooling
and digestive properties; and is commonly used in throat, ulcers by
reducing inflammation etc
The Pharma Research (T. Ph. Res.), (2011), 5(2); 273-293 ACACIA CATECHU WILLD–A GIFT FROM AYURVEDA TO MANKIND” –
A REVIEWLakshmi.T , Anitha Roy
Use of Acacia catechu C.I in breast feeding.
Side Effect:Hypotension
खर्दरथय ििा क्िािो यिाlÉÏक्िाि एि च
क्िािश्र्च तनम्बमूलथय दन्िरोगतनिारणैः
।। (हा.सां.3.46.14)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
 Significant reduction of blood glucose level was observed in non
diabetic albino rats following single dose treatment with the test drug at a
dose of 500 mg/kg, p.o. ( P <0.01). Significant reduction of blood glucose
level was also evident in diabetic rats at doses of 250 and 500 mg/kg
( P <0.001). In the present study, preliminary phytochemical screening
of Acacia catechu found the presence of flavonoids and reports
substantiate the presence of
catechutanicacid, quercetin,catechin,pseudotannin,phlabotannin,polypheno
ls, epicatechin and cyanidanol compounds in A. catechu . The antimicrobial
and hypoglycaemic properties of Acacia catechu may be described to the
presence of flavonoids, It is thought that catechu may contain chemicals
that can decrease inflammation and kill bacteria.
which have been shown to inhibit cyclooxygenases and promote β-cell
regeneration besides having insulin secretagogues and antioxidant
properties.
Antipyretic, antidiarrhoeal, hypoglycaemic and hepatoprotective activities of ethyl acetate extract of Acacia catechu Willd. in albino
rats
D Ray1, Kh. Sharatchandra2, IS Thokchom3
drrout.sibaprasad@gmail.com,24/06/2016
Friday
 Active constituent
Tannins
Acts topically as astringent to mucosal surfaces and following oral
ingestion it consequently get hydrolyzed and alter the fluidity of the
bowel contents (so used in anti-diarrheal remedies) .They are also
attributed with anti-hemorrhagic, anti-inflammatory and antacid
properties. Catechin Have significant antioxidant and antimicrobial
effects. It is considered to be the best antioxidant
Flavonoids
Increase secretion of insulin and inhibit cycloxygenase and
lipoxygenase .Thus it possesses anti diabetic and anti-inflammatory
effect.
 Taxifolin Potent Antibacterial agent.
Noreen et. al; Planta Medica 64, 1998; United States. 29.Hocking D. 1993. Trees for Drylands. Oxford & IBH
Publishing Co. New Delhi. drrout.sibaprasad@gmail.com,24/06/2016
Friday
aÉÑaaÉÑsÉ
 L.N: Commiphora mukul
 F.N :Burseraceae
 mÉsÉlMüwÉÉ(pÉÉ):mÉsÉÇ qÉÉÇxÉÇ ÌWûlÉÉÎxiÉ AÌiÉ sÉåZÉlÉiuÉÉiÉ
 aÉÑaÉÑsÉ(ÌlÉ.AÉ):aÉÑQûÌiÉ U¤ ÌiÉ uÉÉiÉUÉåaÉÉiÉ
 xÉ lÉuÉÉå ÌuÉë¼hÉ ÌuÉëwrÉ mÉÑUÉhÉ iÉÑ AÌiÉsÉåZÉlÉqÉ(pÉÉ.mÉë)
रसाञ्जनस्य ् तिः  िञ्र््ूलस्य गुग्गुलोिः 
पशलाजतुप्रयोगश्च सपग्न्न्थरसो प तिः  (अ.हृ.सू.14.23)
्ेदोऽपनले गुग्गुलुिः  (अ.हृ.उ.40.48)
स्थौल्ये
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
 Several possible mechanisms have been proposed for hypolipidemic
activity of guggulsterone. cholesterol 7α-hydroxylase (CYP7A1) the rate-
limiting enzyme in the classic pathway of bile acid synthesis from
cholesterol in the liver (he expression of CYP7A1 is negatively regulated
by bile acids through a negative feedback circuit involving Conversion of
cholesterol to bile acids and subsequent excretion through the
enterohepatic circulation represent a major pathway to remove excessive
cholesterol from the body (Russell 2003). The is several nuclear receptors
including bile acid sensor FXR, liver receptor homolog 1 (LRH-1),
Recent studies have established that guggulsterone is an FXR antagonist
has been suggested as a mechanism for the cholesterol-lowering effect of
guggulsterone
 Bile acid sensor(FXR)-Liver receptor homolog(LRH1)-Small
heterodiametre partner-cholesterol 7 alpha hydroxylase
Russell 2003; Fuchs 2003). T(Urizar et al. 2002; Wu et al. 2002) (Urizar et al. 2002)
(Lu et al. 2000; Goodwin et al. 2000; Davis et al. 2002) drrout.sibaprasad@gmail.com,24/06/2016
Friday
aÉÑQÒûÍcÉ
 aÉÑQÒûÍcÉ(Bh.P): aÉÑQûÌiÉ UZrÉÌiÉ CÌiÉ aÉÑQû UZÉhÉå
 It protects the body against various diseases.
 euÉUlÉÉÍzÉÌlÉ(xÉÉå)
 UxÉÉrÉÌlÉ(pÉÉ)
 uÉrÉxjÉÉ(pÉÉ)
 ÌuÉwÉÎblÉ(pÉÉ)
 aÉÑQÒûÍcÉ euÉU pÉÑiÉÎblÉ uÉÍsÉmÉÍsÉiÉlÉÍzÉÌlÉ(zÉÉå)
uÉrÉxiÉÉmÉlÉ,SÉWûmÉëzÉqÉlÉ(cÉ.xÉÑ4)
xÉuÉïeuÉUWûU(pÉÉ.mÉë)
AqÉëÑiÉÉxuÉUxÉ-ÎeÉhÉïeuÉUWûU(zÉÉ)
euÉU SÉWû lÉÉzÉlÉ(rÉÉå.U)
पवष्ज्वरे:पिफलायािः  कषायं वा गुडूच्या रस्ेव वा (र्.पर्.3.299)
रसायने (र्.पर्.1/3/31)
मण्डूकण्यायाः स्वरसाः प्रयोज्याः क्षीरेण यष्टीमकुकस्य चूणयम्
रसो गुडूच्यास्तु समूलपुष्पयााः कल्काः प्रयोज्याः खलु शंखपुष्पयााः
L.N:Tinospora cordifolia,(Willd)
F.N: Menispermaceae
,
xÉÑ´ÉÑiÉ:
uÉåÎssÉiÉMü xÉÏuÉlÉ(xÉÑ.xÉÑ.25/21)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
Enhanced lysozyme production was reported at different time intervals
 Ethanolic extract of stem and leaves of T.Cordifolia
exhibits the significant antipyeretic activity(vedavathy
,rao)
 Int J Ayurveda Res. 201
0
 Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) – validation of the Ayurvedic pharmacology through
experimental and clinical studiesAvnish K. Upadhyay, Kaushal Kumar,1 Arvind Kumar,2 and Hari S. MishraAudrrout.sibaprasad@gmail.com,24/06/2016
Friday
aÉÉåZÉÑU
 L.N:Tribullus terestriss(Zygophallaceae)
 mÉsÉlMüwÉÉ(pÉÉ):mÉsÉÇ qÉÉÇxÉÇ ÌWûlÉÉÎxiÉ AÌiÉ MÇüOûÌMüiuÉÉiÉ
cÉUMü
qÉѧÉÌuÉUåcÉÌlÉrÉ,zÉÉåjÉWûU
qÉѧɢÑüdlÉ
AÌlÉsÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/40)
Yatra Akrutihi, tatra gunaaha
vasanti.
Tribulus fruits have quite
resemblance with oxalate stones of
kidney and bladder
Oxalate stone structure T. Fruit
Interesting Fact
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
 Anti-cholestrolemic effect: Saponin fraction
of dried root, administered by gastric intubation
to rabbits decreased the development of protein,
carbohydrate, lipid dystrophy of the liver vs
cholesterol loaded animals. [12]
 Hypoglycemic and hypolipidemic
effects: The extract of both T alatus and T
terrestris significantly decreased the blood glucose
levelsin diabetic rats. [29]
drrout.sibaprasad@gmail.com,24/06/2016
Friday
cÉ¢üqÉSï
L.N:Cassia tora f.n: Caesalpinacea
MÑü¸WûÉ(pÉÉ.mÉë)
SSìÓblÉ(pÉÉ.mÉë)
mÉÉmÉbÉÉÌiÉ(xÉÉ
Kharjughna(Dh.Ni)
चक्रमदिकबीजातन जीरकां च समाांशकम ् ।
थिोकां सुदशिनामूलां दद्रुकु ष्ठविनाशनम ् ।। (बां.से.कु ष्ठ.67)
Seed paste with jeerak and sarkara in equal quantity is applied
externally in eczema,leprosy, tinea, allergic
dermatitis, psoriasis, å)
Eng.Name: Ring worm plant
Dadrukanduhara, Kantikara:Dh.Ni
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
 The major antifungal compound was identified as
chrysophanic acid-9-anthrone, the structure of
which was assigned on the basis of its chemical
properties and uv, ir, nmr and mass spectral
analysis. The compound was active against
Trichophyton rubrum, T. mentagrophytes,
Microsporum canis, M. gypseum and Geotrichum
candidum.Opportunistic diseaseas.
Isolation of chrysophanic acid-9-anthrone, the major antifungal principle of Cassia tora.
Acharya TK, Chatterjee IB drrout.sibaprasad@gmail.com,24/06/2016
Friday
ÍcɧUçMü
 Vahnikrut(xÉÉå) – Improves digestion strength
Pachana (pÉÉ.mÉë) digestive
Laghu (pÉÉ.mÉë)– light to digest
Kushtahara(cÉ) – useful in skin diseases
AlÉsÉ(pÉÉ.mÉë)
 ÌSmÉlÉ(pÉÉ.mÉë)
 ÌSmrÉMüÉ(pÉÉ.mÉë)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
ÎeÉuÉliÉÏ
 L.N: Leptadenia reticulate(Retz.)
 F.N: Asclepiadaceae
 aÉU¾èiÉ
 ÎeÉuÉuÉÍkÉïlÉÏ(xÉÉå);ÎeÉuÉÇ mÉëÉhÉzÉÌ£ü uÉkÉïrÉÌiÉ CÌiÉ
 uÉsÉuÉÍkÉïÌlÉ(xÉÉå)
 mÉëÉhÉSÉ:(UÉ);mÉëÉhÉzÉÌ£ü SSÉÌiÉ CÌiÉ
cÉUMü: uÉrÉ:xiÉÉmÉlÉ, eÉÏuÉlÉÏrÉ,qÉkÉÑUxMülS
A.¾û:eÉÏuÉlÉÏrÉ mÉÇcÉqÉÑsÉ(A.¾Òû.xÉÑ15/8)
Måü.ÌlÉ:xÉuÉïSÉåwÉblÉÏ uÉsrÉÉ ÌuÉëwrÉÉ UxÉÉrÉlÉÏ
drrout.sibaprasad@gmail.com,24/06/2016
Friday
पवषे
तण्डु लीयकजीवन्तीवाताधकु सुपनषण्णकािः 
र्ुच्र्ू्धण्डूकिणी र् शाकञ्र् कु लकं प त् ,
, (र्.पर्.23.225)
Reported research Activity
 Anticarcinogenic ,Activity of Leptadenia reticulata
against Dalton’s Ascitic Lymphoma
 L. Sathiyanarayanan, Sinnathambi Arulmozhi, N.
Chidambaranathan
 antifungal.,
 antioxidant,
 cardioprotective.
galactogogue
drrout.sibaprasad@gmail.com,24/06/2016
Friday
̧ÉuÉëÑiÉ
L.N:Operculina turpethum(L.)
CONVOLVULACEAE
ÌlÉzÉÉåjÉ(pÉÉ):ÌlÉuÉÉUrÉÌiÉ zÉÉåjÉ UåcÉlÉiuÉÉiÉ
UåcÉlÉÏ(pÉÉ)
xÉUhÉÉ(A.ÌlÉ)
̧ÉuÉëÑiÉxÉÑZÉÌuÉUåcÉlÉÉlÉqÉ(cÉ.xÉÑ.25/40)
pÉåSlÉÏrÉ qÉWûÉMüwÉÉrÉ(cÉ,xÉÑ 4/4)
ÌuÉUåcÉlÉå ̧ÉuÉëÑiÉqÉÑsÉqÉ ´Éå¹qÉ(cÉ.Mü.7/1)
xÉÑ´ÉÑiÉ:AkÉÉåpÉÉaÉWûU(xÉÑ.xÉÑ.39/3)
xiÉoSÉÌlÉ,xÉÑmiÉÉÌlÉ,AxuÉåSÉÌlÉ,MühQÒûsÉÉÌlÉ MÑü¸: ̧ÉuÉ×iÉ(cÉ.ÍcÉ 7/57)
zÉÉåTümÉÉhQèuÉÉqÉrÉ msÉÏWûÉlÉ WûÎliÉ ´Éå¸Éå ÌuÉUåcÉlÉå (kÉ.ÌlÉ)å
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Anti-inflammatory activity-
An experimental study was carried out(Rajashekar M et al;
2006) to evaluate the effect of oral administration of root
powder of O. turpethum and its polyherbal formulation
Avipattikar churna on rat paw edema in albino rats. Results
indicated that pretreatment with the root powder of O.
turpethum and Avipattikara churna (100 mg/kg body
weight)reduced the formalin induced edema volume tothe
extent of 36.45% and 27.11%respectively.
Rajashekar M. Bhande, Laakshmayya,Pramod Kumar, Nitin K. Mahurkar, & S.Ramachandra Setty, Pharmacological
Screening of Root of OperculinaTurpethum and its Formulations. Acta Pharmaceutica Sciencia, 48: 11-17, (2006).drrout.sibaprasad@gmail.com,24/06/2016
Friday
SÉÂWûËUSìÉ
 Botanical name – Berberis aristata Dc.,
Family – Berberidaceae
Ì¢üÍqÉWûUÉ(xÉÉå)
mÉÇcÉmÉÇcÉÉ(pÉÉ):
mÉÉMüÉlÉliÉUÇ mÉcÉÌiÉ kÉÉiÉÑmÉÉMÇü MüUÉåÌiÉ rÉ¢ÑüiÉ E¨ÉåeÉMü
MüUÉåÌiÉ cÉ
ÌuÉzÉÉåÍkÉlÉÏ(Måü.ÌlÉ)
SÉuÉÏïï iuÉcÉÇ MüsMåülÉ mÉëkÉÉlÉÇ uÉëhÉUÉåmÉhÉqÉ (cÉ¢üS¨É)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
व्रणे
दुवाधस्वरसपसद्धं वा तैलं कप्िल्लके न वा
दावीत्वर्श्च कल्के न प्रधानं व्रणरोिण् (र्.पर्.25.93)
Research
 The main constituents of root were identified as
berberine, berbamine and palmatine through HPTLC.
The extract besides being safe, lowered the blood
glucose significantly without any hypoglycemic effect on
their control counterparts. It increased CAT, SOD,
GPx, GR activity significantly and reduced lipid
peroxidation (41.6%) and protein carbonylation
(30.15%). It also increased the glucokinase and glucose-
6-phosphate dehydrogenase activities Thus, the extract
of Berberis sristata (root) has strong potential to
regulate glucose homeostasis through decreased
gluconeogenesis and oxidative stress.
Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in
diabetic rats
Jyotsna Singh, Poonam Kakkar
drrout.sibaprasad@gmail.com,24/06/2016
Friday
The aqueous root extract of Berberis aristata
showed good hepato protective activity when
administered at doses of 10mg/kg and 20 mg/kg; i/p
and the effects were dose dependent. Serum ALT,
AST, ALP activities significantly decreased in a dose-
dependent manner The present study demonstrates
that berberine possesses hepatoprotective effects
against CCl4-induced hepatotoxicity and that the
effects are both preventive and curative.
HEPATOPROTECTIVE ACTIVITY OF BERBERISARISTATA ROOT EXTRACT AGAINST CHEMICAL INDUCED ACUTE
HEPATOTOXICITY IN RATS
Navdeep Dehar, Rani Walia, R.BVerma, Pinky Pandeydrrout.sibaprasad@gmail.com,24/06/2016
Friday
SìɤrÉÉ
L. n – Vitis vinifera Linn
Family-Vitaceae
uÉëÑÇWûÍhÉ(Mãü.ÌlÉ)
rɤqÉÎblÉ(zÉÉå.ÌlÉ)
´ÉqÉÉmÉWûÉ(pÉÉ.mÉë)
Resveratrol present in grapes is a very
potent anti – oxidant. Grapes are rich
sources of vitamin E (anti-oxidant vitamin)
MüÉxÉWûU,euÉUWûU,´ÉqÉWûU qÉWûMüwÉÉrÉ(cÉ.xÉÑ4),
xÉÇiÉmÉïÍhÉrÉ (cÉ.xÉÑ 23/38)
TüsÉÉå¨ÉqÉÉ(cÉ.xÉÑ 25/39)
uÉëÑWÇûÍhÉ ÌuÉëwrÉÉ(cÉ.xÉÑ 27/125)
द्राक्षाबिल्वशिवािीनाां फलां िुष्कां गुणाचिकम् ||५१||
– Bhavaprakasha
grapes with milk is best avoided
(samjog virudha)(ch su 26/19)
Gostani variety draksha best
Draksha help to strengthen lungs.
Expectoration of kapha or
Phlegm achieved with the help of
this fruit. Thus grapes main
ingredients ayurvedic
respiratory conditions like
Tuberculosis, cough, bronchitis
क्षयरोगे(सु.उ.41.40)
द्राक्षापसता्ागपधकावले िः  सक्षौद्रतैलिः  क्षयरोगघाती
drrout.sibaprasad@gmail.com,24/06/2016
Friday
ÌlÉqoÉ
L.N: Azadirachta indica A.Juss
F.N: Meliaceae
 AËU¹(pÉÉ.)lÉ ËU¹qÉzÉÑpÉqÉxqÉÉiÉ,xÉuÉïUÉåaÉlÉÉzÉMü
 ¢ÑüÍqÉblÉ(Mãü.ÌlÉ)
 NûSïlÉ(Mãü.ÌlÉ)
 ÌmÉcÉÑqÉSï(pÉÉ.mÉë):
 ÌmÉcÉÑqÉ MÑü¸qÉ qÉSïrÉÌiÉ lÉÉzÉrÉÌiÉ
 mÉÑrÉÉËU(zÉ.)
Charaka Samhita
Kandughna(ch.su4)
Tiktaskandha(ch.vi 8/143)
Kusthanashak kasaya
(ch.chi 7/92)
Jantudagdha,Lashikaprasut
kustha:Nimba-vidang pana &
lepa with gomutra(ch.chi 8/157)
Neem seed oil and leaf extract is
spermicidal,
inhibits spermatogenesis,
antiimplantation,abortificient properties
wchich enables to prepare contraceptive
from neem oil(Sinha Et all.1984)
YONI DHUPANWITH
NIMBA KASTHA BEFORE
VYAVAYA
CONTRACEPTIVE
(YOGATANAKAR)
यिः  खाादेदभयाररट्ररटा्लकं तथा
स जयेत सवधकु ष्ठापन ्ासादूर्ध्वं न संशयिः  (ग.पन.2.36.87)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
कक्रभमरोगे
तनम्बििसमुद्िूिां रसां क्षौद्रयुिां विबेि् ।
धत्तूरििजां िावि कक्रभमनाशनमुत्तमम ् ।। (िा.प्र.चच.7.24)
In vitro ovicidal and larvicidal activity of Azadirachta indica
extracts on Haemonchus contortus

drrout.sibaprasad@gmail.com,24/06/2016
Friday
mÉÉPûÉ
 Botanical name – Cissampelos pareira
Family – Menispermaceae
 SÏmÉlÉÏ(UÉ.ÌlÉ)
 mÉÉmÉcÉåÍsÉMüÉ(ÌlÉ.AÉ):mÉÉmÉcÉ uÉÉrÉÑ cÉåsÉrÉÌiÉ ÌlÉuÉÉUrÉÌiÉ
 qÉWûÉãeÉxÉÏ(xÉÉå)
 U£üÎblÉ(xÉÉå)
 ÌuÉwÉWûl§ÉÏ(xÉÉå)
 uÉÉåkÉÌMü(A)
mÉÉPûÉ AÌiÉxÉÉUzÉÑsÉÎblÉ MüTüÌmÉiÉeuÉUmÉWûÉ
 UÉeÉmÉPûÉ iÉjÉåuÉ U£üxÉÇaÉëÉÌWûÍhÉ cÉ xÉÉ(zÉÉå)
Charak
Sandhaniya
Mahakashaya(ch.su4)
M.C of Pushyanuga
Churna
अशधपस
िाठया वा युतं तक्रं वातवर्ोऽनुलो्न् (अ.हृ.पर्.8.61)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
mÉÑlÉlÉïuÉÉ
zÉÉåjÉÎblÉ(pÉÉ)
 xɱÉåÌuÉzÉÉåÌwÉ(Måü);xÉkrÉÉå zÉÉåjÉ ÌuÉzÉÉåwÉrÉÌiÉ
 xÉÉËUÍhÉ(xÉÉå)
 ÌuÉwÉÎblÉ(UÉ):It is hepatoprotective and detoxifies the toxins
mÉÑlÉlÉïuÉÉ zÉÉMü-ÌuÉzÉåwÉÉiÉ zÉÉåTülÉÉzlÉ(xÉÑ.E.46/255)
िुननधवापन्बिटोलशुण्ठीपतक्ता्ृतादाव्यधभयाकषायिः 
सवाधङगशोफोदरकासशूलश्वासापन्वतं िाण्डु गदं पन पन्त (वृ.्ा.38.3)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Research
 Ethanol extract of leaves at dose of 400mg/kgexhibited
maximum anti-inflammatory effect with30.4, 32.2, 33.9 and
32% with carrageenin,serotonin, histamine and dextran
induced rat pawedema models, respectively.Ethanol extract
of stembark also exhibited COX-1 and IC50value of
100ng/ml proving the drug use in thetreatment of
inflammatory condition. Antiinflammatoryactivity was
assessed using extract of latex of plant by using a carragenan
induced inflammatory model.47
Anti-inflammatory activity of Boerhaavia
 diffusa.48 Bhalla, T.N., Gupta, M.B., Sheth, P.K., and Bhargava,
K.P., Antiinflammatory activity of Boerhaavia diffusa. Indian
Journal of Physiology and Pharmacology 1968; 12:37
drrout.sibaprasad@gmail.com,24/06/2016
Friday
oÉÉMÑüÍcÉ
 L.N:Psoralea corylifolia
 F.N:Fabaceae
 uÉÉMÑüÍcÉ(ÌlÉ.AÉ):uÉÉiÉÇ MüÉåcÉrÉÌiÉ CÌiÉ
 MÑü¸ÎblÉ(pÉÉ.mÉë)
 qÉsÉrÉÑ(A.ÌlÉ)
 zÉÍzÉsÉåZÉÉ(pÉÉ.mÉë)
 ͵ɧÉÎblÉ(ÌmÉë)
सोमराजीििां चूणं श्रृांगबेरसमच्न्ििम ् ।
उद्िििनभमदां हच्न्ि कु ष्ठमुग्रां कृ िाथिदम ् ।।
(िा.प्र.चच.54.53)
अवल्गुजाद बीजकषं पिबेदुषणेन वाररणा
भोजनं क्षीरसपिधर्भयां सवधकु ष्ठ रं िर् (बं.से.कु ष्ठ.101)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Mode of Action
 The drug Bakuchi dilates the arterioles of the
subcapillary plexuses, so that the plasma is increased in
this area. The skin becomes red and the melanoblasts
(pigment-forming cells) are stimulated. In leukoderma,
melanoblasts do not function properly and their
stimulation by the drug leads them to form and exudate
pigments, which gradually diffuse into the white
leukodermic patches. Psoralen has been found to
intercalate into DNA, where they form mono- and di-
adducts in the presence of long wavelength UV light
and thus are used for the treatment of hypo-pigmented
lesions of the skin, such as leukoderma. [57]
Vaidya AD. Reverse Pharmacological correlates of Ayurvedic drug actions. Indian J
Pharmacol 2006;38:311-5
drrout.sibaprasad@gmail.com,24/06/2016
Friday
pÉssÉÉiÉMü
Latin Name:Semicarpus anacardium Linn
F.N: Anacardiacea
Ì¢üÍqÉblÉ(UÉ)
pÉÑiÉlÉÉzÉlÉ(ÌmÉë)
pÉåSlÉ(xÉÉå)
uÉÉiÉÉËU(UÉ)
zÉÉåTüÌ¢üiÉ(pÉÉ)
Charaka –
Deepaneeya –Bhedaniya-Kushtaghna
भल्लातकापस्थस्वरसं पवडङगाधेन संयुत्
सूयधतप्तं पल ेद युक्त्या पसद्धं पक्रप्पवनाशन्
. (ग.पन.2.6.39)
पवषसंसृटे अञ्जने
........ िुषिं भल्लातकस्य वा (सु.क.1.71)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
Evaluation of anthelmintic activity of nuts of
Semecarpusanacardium
The anthelmintic activity of different extracts of nuts
of Semecarpus anacardium were evaluated separately on adult
Indian earthworm (Pheritima posthuma). It was found that
petroleum ether, chloroform extract of S. anacardium (PESA
and CESA, respectively) showed better anthelmintic activities
than ethanol (EESA) and aqueous (AESA) extract of it.
Antimicrobial activity of Semecarpus anacardium Linn.
nut extract
Alcoholic extract of dry nuts of S.anacardium showed dose
dependent antimicrobial activity in vitro against Aspergillus fumi
gatus andCandida albicans. At 400 mg/ml concentration, growth
of both the fungi was inhibited and considerable reduction in
size of cells and hyphae was observed.
Analgesic activity and acute toxicity study of Semecarpus
anacardium stem bark extracts using mice
Sharma, Kanika Shukla, Sunil DuttMehta, PoojaBhatnagar, Maheep
drrout.sibaprasad@gmail.com,24/06/2016
Friday
uÉÉxÉÉ
L.N:Adhatoda vasica
F.N:Acanthaceae
MüTüWûÉ(xÉÉå)
MüxÉlÉÉåimÉÉOèlÉ(zÉ)
SliÉxÉiuÉmÉëSÉÌrÉ(xÉÉå):SliÉÉlÉÉqÉ xÉiuÉÇ uÉsÉqÉ SSÉÌiÉ
ÍpÉwÉMü(pÉÉ):AlÉåMü urÉÉÍkÉlÉÉqÉ xÉÉkÉMü
qÉÉiÉÉ(pÉ);qÉiÉåuÉ ÌWûiÉMüÉËUÍhÉ UÉåÌaÉhÉÉqÉ ÍpÉwÉeÉÉÇ cÉ
U£üÌmÉiÉmÉëxÉÉÌSÌlÉ(qÉ.ÌlÉ)
U£üqÉѧÉÎeÉiÉ(xÉÉå)
uÉxÉÉÌSÌlÉ(UÉ):uÉxÉÉqÉ xlÉåWûqÉ ÌuÉlÉÉzÉrÉÌiÉ
ÍxÉÇÌWûMüÉ(pÉÉ):ÌWûlÉÎxiÉ UÉåaÉÉlÉ CÌiÉ
drrout.sibaprasad@gmail.com,24/06/2016 Friday
शकि रामधुसांयुक्िैः के िलो िा श्रृिो ऽवि िा ।
िृषैः सद्यो जयत्यस्रां स ह्यथय िरमौषधम ् ।। . . .
, (अ.हृ.चच.2.24-25)


ििोलतनम्बयष््याहृिासाजात्यररमेदसाम ् ।
खर्दरथय िरायाश्च िृिगेिां प्रकलिना ।।
(अ.हृ.उ.22.106)
Research
Pure vasicine - Dhuley (1999)Marked bronchodilator activity
evaluated on contracted trachea or constricted trachea bronchial
tree and act as a soothing agent.
drrout.sibaprasad@gmail.com,24/06/2016 Friday
िासायाां विद्यमानायामाशायाां जीवििथय च ।
रक्िवित्ती क्षयी कासी ककमििमिसीदति ।।
(िृ.मा.9.11, हा.सां.3.10.24)
वासकस्वरसे िथ्या सप्तधा िररभापवता
कृ षणा वा ्धुना लीढा रक्तपित्तं द्रुतं जयेत (वृ.्ा.9.22)
Summary of Drugs As per synonyms
As Per Doshaghnata
Vata Aam
Marutaghni:Aswagandha Aamaghni: Katuka
Vatari:Erand Aamaha:Aragwadha
Vatahrit:Gambhari
Vatahar:Palasha
Kapha
Kaphadravani:Kantakari
Kaphavirodhi: Maricha
Kaphaha:Vasa
Pitta
Pittavallabha:Ativisha
drrout.sibaprasad@gmail.com,24/06/2016 Friday
Lekhani-Citrak
Rechi- Ankota
Recana-Kampillak
Dipyaka-Ajamoda
Deepani-Citrak
Adhyand:Kokillakhya
Vrishabhi-Kapikachu
Vrishya:Atibala
Vrishyagandhika:Aswagandha
Kamarupini:Aswagandha
Vayastha:Aamalaki
Vayasya:Aamalaki
Rasayani:Aswagandha
drrout.sibaprasad@gmail.com,24/06/2016Friday
As per disease
Pleeha
Pleehari-Aswatha
Pleehashatru:Kokillakhya
Pleehaghna: Rohitak
Kasa
Kashaghni: Kantakari
Kashabhajani: Patola
Kashaghni: Bibhitak
Kashonaptan: Vashak
Switra
Switrabhaisajya: Kakoudumbar
Switraghna:Vakuchi
Malayu:Vakuchi
Kustha
Kusthaha:Aragwadh
Kusthaghni:Kakoudumbar,Bakuchi
Kusthaghnaa:Khadira
Dadrughna:Cakramard
Kusthaveri:Tuvarak
On the Basis Of Diseases
Krimi
Kriminashini:Ajamoda
Krimihara:Daruharidra
Krimighna;Nimba
drrout.sibaprasad@gmail.com,24/06/2016 Friday
PPT ON 50 AYURVEDIC DRUGS BY DR SIBA PRASAD ROUT,IPGT

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PPT ON 50 AYURVEDIC DRUGS BY DR SIBA PRASAD ROUT,IPGT

  • 1. drrout.sibaprasad@gmail.com,24/06/2016 Friday Presenting Scholar Dr. Siba Prasad Rout M.D(2nd Year) Dravyaguna Department, IPGT & RA, Gujarat Ayurved University, Jamnagar- 361 008 Session:2014-2017
  • 2. SìurÉÉhÉÉÇ lÉÉqÉÂmÉÉÍhÉ aÉÑhÉMüqÉÉïÍhÉ xÉuÉïzÉ: mÉërÉÉåaɶÉÉÌmÉ uÉhrÉïliÉå rÉÎxqÉlÉ SìurÉaÉÑhÉÇ ÌWû iÉiÉ|| (P.V Sharma) Dravyaguna shastra is the branch deals with the properties, action & therapeutic effects of various dravyas. Dravyaguna . Vigyan GUNAKARMA VIGYAN (PharmacoDynamics) Gunavigyan (Pharmacology) Karmavigyan (Clinical pharmacology) Prayog vigyan pharmacotherapeutics Namarupavigyan (pharmacognosy) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 3. ï Ì¢ürÉiÉå AlÉålÉ CÌiÉ Ì¢ürÉÉ (Sì.aÉÑ.ÌuÉ) The element which is responsible for the action of a drug is known as ‘’karma’’ Ì¢ürÉÉ sɤÉhÉÇ MüqÉï(lÉÉaÉÉeÉÑïlÉ) The main property of karma is action. In Ayurveda, drugs have been classified according to pharmacological action. If comparative study is done on modes of classification of drugs in Ayurveda and Allopathic, it can be concluded that modern drug classification is similar to ancient one. A. Drugs Acting On Digestive System  Anulomna (Carminative)  Arshoghna  Atisarghna (Antidiarrhoeal)  Kriminghna (Anthelmintic)  Chhardinigrhana (Anti-emetics) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 4. B. Drugs Acting On Respiratory System  Kaphanissaraka (Expectorant):Talishapatra (Taxus baccata)  Kasahara (antitussive) :kantakari(solanum suratens)  Mucolytic expectorant :Vasa(Adhatoda vasica)  Swashara (bronchodialator): Dhatura(Dhatura metal) C. Drugs Acting On Heart Hridya (Cardiac tonics):Arjun(Terminalia arjuna)  Shothghna (Anti-inflammatory): Dashamoola D. Drugs Acting On Circulatory System  Raktaprasadana (Alterative):Sariva(Hemidesmus indicus.) etc.  Raktaskandana (Styptics):Nagakeshar (Messua fera)etc E. Drugs Acting On Nervous System  Nadi balya (Nervine):Ashwagandha (Withania somnifera) and Kapikachu (Mucuna prurita),Bhallataka(Semicarpus anacardium) etc.  Nidrajanana (Hypnotics):. Jatamansi (Nardostachys jatamansi) etc. F. Drugs Acting On Kidney  Ashamrighna (Lithontriptics):. Varuna (Cratevea nurvala) etc  Mutrala (Diuretics):. Gokshura (Tribulus terresteris) and Punarnava (Boerrhavia diffusa) are diuretics. They are used in treating edema.  Mutrasangheneya:udumbar(ficus glomerata) etc G: Miscellaneous Drugs_Rasayana, Vajikarana, Yakritautejjaka (Choleretics) etc
  • 5. :  In this presentation, total 50 dravyas (Drugs) have been reviewed vividly from all Nighantus (lexicons) and the karma (clinical pharmacological) based paryaya (synonyms) only have been assembled .  Around 223 paryayas (synonyms )  Traditional classical claims with evidence based experiments have been summarized here in order to correlate & justify its nomenclature  At the end of presentation, dravyas have been categorized systematically on the basis of their synonyms denoting to their specific karmas . Glimpses of Presentation drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 6. L.N- Trachyspermum roxburghianum D.C F.N: Umbelliferae  Synonyms Based on Karma; ÌSmrÉMüÉ(pÉÉ.mÉë) –It increases digestive fire. Ì¢üÍqÉlÉÉÍzÉÌlÉ(Mæü.ÌlÉ)- Ì¢üÍqÉlÉ lÉÉzÉrÉiÉÏÌiÉ kills the worms Charak- Deepaniya mahakashaya(ch.su4/9) A.H.CHI14/35: Hingwasthak churna-janayanti jatharagni . . vatagulma cha nihanti Vrinda madhav:Ajamodadi vati: Aamvat अजमोदा drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 7. Chemical Content: Apioseglycosider,Apiin,Terpineol T. ammi would increase the secretion of gastric acid; the addition of T. ammi to the infusion increased the amount of gastric acid. Gastric acid secretion was increased nearly four-fold by T. ammi. In experimental rats in vivo, the addition of T. ammi to the diet reduced food transit time and also enhanced the activity of digestive enzymes and/or caused a higher secretion of bile acids.[48](Kohli et all. 1964) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 8. AÌiÉuÉsÉÉ  Latin Name: Abutilon indicum L.  Family Name: Malvaceae AÌiÉuÉsÉÉ(pÉÉ.mÉë):AiÉÏuÉ uÉsÉSÉlÉ MüUÉåÌiÉÌiÉ ÌuÉëwrÉÉ (kÉ.ÌlÉ:): It is an effective Aphrodisiac. uÉ××wrÉaÉÎlkÉMüÉ(UÉ.ÌlÉ): uÉ×wrÉÉ zÉÑ¢üuÉÍkÉïÌlÉ,aÉÎlkÉMüÉ uÉåaÉeÉlÉÌlÉ, aÉÎlkÉMüÉ uÉåaÉeÉlÉÌlÉ,uÉ×wrÉÉ cÉÉxÉÉæ aÉÎlkÉMüÉ cÉ. (UÉ.ÌlÉ) Formulation: Balaristha,Balataila(mɤrÉÉbÉÉiÉ-AlÉÑuÉÉxÉlÉ-xÉÑ.ÍcÉ.5/19). Khirabalataila nasya(AÌSïiÉ-xÉÑ.ÍcÉ.5/22) Charak: Valya mahakashaya(ch su 4/18) Vrimhaniya mahakashaya(ch su 4/28) xÉÉaÉëÉÌWûMü uÉsrÉ uÉÉiÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/40) Rasayan,vajikaran(ch.chi 1.2.12) Shukra sruti vridhikar (Dalhan) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 9. Chemical Content Ephedrin(sympathomimetic) steroids, triterpenoids, alkaloids, saponins,flavonoids, A)On Female Libido Methanolic extract of areal parts of Abutilon indicum was investigated for the libido enhancement activity at doses 100, 200 and 400 mg/kg using automated runway methodology and copulatory behavior models. The results revealed that the extract significantly improved the runway parameters and copulatory behavior exhibiting its effectiveness in enhancing the female libido1 B)As Immunomodulatory In an experimental study the rasayana drugs namely atibala.bala,mahabala,bhumibala, have been screened for their immunonenhancing properties,Animals of drug treated group showed statistically an enhanced properties of Anti S typhi O antibodies,Abutilon indicumwasbestinaugmentingantibodyproduction.2 1) Effect of Abutilon indicum extract on FemaleLibido in Rats Khadabadi SS1* and Bhajipale NS2Kirtikar K.R, Basu B.D; 2) IndianMedicinal Plants. Allahabad, India.1956, p. 314-316. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 10. AÌiÉÌuÉwÉÉ  Latin Name: Aconitum heterophyllum(Wall.exRoyle)  Family; Ranunculaceae  AÌiÉxÉÉUÎblÉ(kÉ): AÌiÉxÉÉUqÉ lÉÉzÉrÉÌiÉ  ÌmɨÉuÉssÉpÉÉ(kÉ): ÌmɨÉUÉåaÉåwÉÑ TüsÉmÉëSÉ  zÉÉåTümÉWûÉ(kÉ.ÌlÉ):  ÍzÉzÉÑpÉåzÉerÉÉ(xÉÉå):uÉÉsÉUÉåaÉåwÉÑ TüsÉmÉëSÉ useful in child diseases. AÉqÉÉÌiÉxÉÉU:  AÉqÉÉÌiÉxÉÉUå:S±ÉiÉ xÉÉÌiÉÌuÉwÉÉqÉ mÉårÉÉqÉ xÉÉqÉå xÉqsÉÉqÉ xÉlÉÉaÉUqÉ(cÉ.xÉÑ2/18) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 11. Formulation:  Balachatrubhadra churna Chemical: Atisenol,Heteratishin Research  In a clinical trial comprising 30 patients,Ativisha is found to be effective in Atisara. the ant-diarrheal activity of roots of A. heterophyllum may be attributed to an antisecretory and anti-enteropooling type effect as a result of reactivation of Na + and K + ATPase activity mediated through NO pathway. EAH causes either a decrease in mucosal secretion or increase in mucosal absorption, which allows the feces to become desic cated thus retarding its movement through the colon. The above activity was well supported with a potential antibacterial activity. Thus, the present study justifies the use of roots of A. heterophyllum in treatment of diarrhea. Antisecretory and antimotility activity of Aconitum heterophyllum and its significance in treatment of . diarrhea  Siva Hemalatha, Divya Jain, Dinesh K Patel, Satyendra K Prasad,Alakh N SahuIndian Journal of Pharmacology,Vol. 46, No. 1, January-February, 2014, pp. 82-87 मधुनाऽतिविषाश्रृङ्गीविप्िलीलेहयेच्छिशुम ् । एकाां िाऽतिविषाां कासज्िरछिर्दिभिरर्दििम ् ।। (अ.हृ.उ.2.57) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 12. AeÉÑïlÉ  Latin Name: Terminalia arjuna  Family Name:Combretaceae  ™SìÉåaÉuÉåËU(Sa)  µxÉlÉåxuÉU(K.N) AeÉÑïlÉxrÉ iuÉcÉÉ ÍxÉkÉqÉ ¤ÏUqÉ rÉÉåerÉqÉ ¾èSÉqÉrÉå ÍxÉiÉrÉÉ mÉlcÉqÉÑsrÉÉ uÉÉ oÉsÉrÉÉ qÉkÉÑMåülÉ uÉÉ (ÌuÉë.qÉÉ)  Milk processed withsarkara,panchamula,bala, and madhuka should be used in cardiac disorders. cÉÑlÉïqÉ MüMÑüxiÉoÉqÉÏxjÉqÉ uÉxÉ¢üxÉqÉ pÉÌoÉiÉqÉ uÉÉWÒûuÉÉUqÉ bÉëÏiqÉkÉÑÍxÉiÉÉåmÉsÉqÉ sÉåWûqÉ ¤rÉxuÉÉzÉMüÉxÉÌmÉiÉWûUqÉ (pÉÉ.mÉë UeÉrZqÉÉ ÍcÉ 12/29) Powdered Arjun bark impregnated with vasa juice several times should be taken with ghee honey sugarcandy.it alleviates cough,swasa,pitta etc.  Chemical content  Arjunic acid,Tannins,Arjunolic acid drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 13.  The present study demonstrated prophylactic and therapeutic potential of Terminalia arjuna bark extract in isoproterenol (ISO)-induced chronic heart failure (CHF). Fifteen days after injection of ISO (85 mg/kg twice at an interval of 24 h, s.c), rats showed fall of left ventricular pressure, cardiac contractility index (LV (dP/dt)max/LVP), and rise in cardiac output ,LV end-diastolic pressure. CHF rats showed a significant increase in serum creatine kinase isoenzyme-MB (CK-MB) increased level of cytokine tumour necrosis factor-α (TNF-α) along with histological changes in heart were also observed in CHF rats. . Cardioprotective action of T. arjuna was comparable to fluvastatin, a synthetic drug. The results suggest that T. arjuna bark extract has a significant prophylactic and therapeutic beneficial effect on protection of heart against ISO-induced CHF possibly through maintaining endogenous antioxidant enzyme activities, inhibiting lipid peroxidation and cytokine levels.  mÉ Mechanistic Clues in the Cardioprotective Effect of Terminalia Arjuna Bark Extract in Isoproterenol-Induced . . . . Chronic Heart . . . Failure in Rats  Adila Parveen, Rashmi BabbarSarita AgarwalAnita Kotwani Mohammad Fahim  mÉÉjÉï ¤ iÉå AÌlÉsÉå pÉalÉå U£üxiÉqpÉå oÉsÉåÌWûiÉ(zÉÉå.ÌlÉ)drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 14. AzÉÉåMü Latin Name_Saraca ashoka Family Name-Caesalpinacea  xiÉUÏÌmÉërÉ: used in all gynaecological disorders  AzÉÉåMü:lÉ zÉÉåMüÉxqÉÉiÉ  xqÉUÉÍkÉuÉÉxÉ: xqÉU xqÉëÑÌiÉ iÉzrÉ AÍkÉuÉÉxÉ Chemical content: arjunic acid,fredelin,tannin अशोकवल्कलक्वाथश्रृतं दुग्धं सुशीतल् यथाबलं पिबेत प्रातस्तीव्रासृग्दरनाशन् . , (वृ.्ा.63.5) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 15. Research  Oxytocic activity of the plant was seen in rat and human isolated uterine preparations. Estrogen-primed or gravid uterus was more sensitive to the action of the alcoholic extract. The bark of Saraca ashoka, which is the real potent drug, is reported to have a stimulating effect on the endometrium and ovarian tissue tonic contraction and is therefore very valuable in treating problems like menorrhagia due to uterine fibroids, in leucorrhea and in internal bleeding. Ashoka or Saraca indica is helpful in all cases of uterine bleeding.(B.N GHOSH,PMMT)  (http:// www. da-academy org/dagardenssaraca1.html. ) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 16. Anti convulsant activity of methanolic extract of leaf of Saraca indica Linn shows that it could have blocked the seizure spread by inhibiting Na+ channels and glutamatergic excitation through NMDA enhancement of GABA activity [26]. Hence from the results indicated the presence of anxiolytic activity inthe Saraca indica Linn. leaf extract by act through potentiating the GABA inhibition in the CNS as that of standard drug diazepam. Neuropharmacological Screening of Saraca Indica leaves  Talever Singh*, Snigdha Gupta, Milind Pande, Mrs Akansha Singh Guru Drone Journal of Pharmacy and Research. 2014; 2(2): 30 -37 S. Ashoka extracts typically relieve pain by acting on both the central and peripheral nervous systems Experimental evaluation of analgesic property of bark skin of Saraca indica (Ashoka) and Shorea robusta (Shal) Poonam S. Mohod1, C. R. Jangde2, S. D. Narnaware3, Subhash Raut4 drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 17. AµÉaÉlkÉÉ  Latin name:Withania somnifera Dunal  Family Name:Solanacea  mÉѧÉSÉ(ÌlÉ.AÉ):mÉѧÉÇ SSÉÌiÉ zÉÑ¢üuÉkÉïlÉÉjÉï  ÇqÉÉÂiÉÎblÉ(xÉÉå)  MüÉqÉÂÌmÉÍhÉ(UÉ.ÌlÉ):  MüÉqÉxrÉ ÂmÉÇ pÉuÉirÉxrÉuÉÉ It promotes complexion  uÉsrÉÉ(kÉ.ÌllÉ),ÌuÉëwrÉÉ(Måü.ÌlÉ) Vajikaran(pÉÉ.mÉë) Shukrala:(zÉÉ) cÉUMü Valya,vrihmaniya Alepan in Rajyakhma (ch.chi 8/77) अश्िगन्धाकषायेण कलकक ैः क्षीरां चिुगुिणम ् । घृिां िक्िां िु िािघ्नां िृष्यां माांसवििधिनम ् ।। (िृ.मा.22.73) Vatavyadhi; Ashwagandha kashaya with four times ghee and milk pacifies the vata drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 18. Rasayan-One who takes the powder of aswagandha root in late winter mixed with honey & ghee along with milk regains the youthfulness. Sedative effect: In a very high dose, it may have sedative effect. Hence some experts advice to avoid it during day िीताऽश्वगन्धा ियसाऽधध्ासं घृतेनं तैलेन सुखाा्बुना वा कृ शस्य िुपटं विुषो पवधत्ते बालस्य सस्यस्य यथा सुवृपटिः (अ.हृ.उ.39.158) Chemical: Withanol:Aphrodisiac Enhygriene: Lowering B.P Somniferin:Sedative Effect drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 19.  It enhances the function of the brain and nervous system and improves the memory.  It improves the function of the reproductive system promoting a healthy sexual and reproductive balance.  Being a powerful adaptogen, it enhances the body’s resilience to stress. Ashwagandha improves the body’s defense against disease by improving the cell-mediated  immunity. It also possesses potent antioxidant properties that help protect against cellular damage caused by free radicals  Withania somnifera treatment prevents, decrease of adrenal cortisol and ascorbic acid.  Ashwagandha given to a group of mice with milk injection produced reduction in leucocytosis.  Anabolic effects:  Cognition Promoting Effect  roots of Ashwagandha  significantly reversed ibotenic acid induced cognitive defects in Alzheimer’s disease model (Bhattacharya et al., 1995)  Anxiolytic effect  Singh et al., Afr J Tradit Complement Altern Med. (2011) 8(S):208-213 208  AN OVERVIEW ON ASHWAGANDHA: A RASAYANA (REJUVENATOR) OF AYURVEDA  Narendra Singh#, Mohit Bhalla, Prashanti de Jager* and Marilena Gilca** drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 20. असनैः (बीजकैः)  Latin Name: Pterocarpus marsupium Roxb.  Family name: Fabaceae  MüÉzrÉï: it causes emaciation. Sesamum oil in the morning with decoction of heartwood . . of asana mixed with honey effective in sthaulya. अपतस्थूलशरीरो यपस्तलतैलं mÉëÉगे पिबेत पिबेदसनसारस्य क्वाथं वा ्धुसंयुत् (वै.्.12.30) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 22. अच्थिसांहारैः Latin name:Cissus quadrangularis Linn Family name:Vitaceae AÎxiÉxÉÇrÉÉåeÉMü:(pÉÉ.mÉë):AÎxiÉÌlÉ pÉalÉxÉÇWûÉUrÉÌiÉ rÉÉåeÉrÉÌiÉ CÌiÉ Cures fractures, dislocation and causes reunion in fractures. सघृिेनाच्थिसांहारां लाक्षाां गोधूममजुिनम ् । सच्न्धमुक्िेऽच्थििग्ने च विबेि् क्षीरेण मानिैः । (िृ.मा.46.8) One should take the combination of asthisamhara, lac,wheat flour,Arjun with milk added with ghee in case of dislocation of joints and bone fracture. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 23. Research  The anabolic steroids from Cissus quadrangularis showed marked influence in the rate of fracture healing by influencing early regeneration of all connective tissues involved in the healing and quicker mineralization of callus.1  Systemic use of Cissus quadrangularis restores fracture in four weeks in trial group while the controls required six weeks. That is due to increase in mucopolysaccharides level,proliferation of osteoblastic, chondroblastic and cartilage proliferation, increased mineralization in the callus. Thus the parenteral administration of the total extract of Cissus quadrangularis not only neutralized the anti-anabolic effect of cortisone in healing of fractures but also enhances the mineralization of the callus possibly due to its vitamin contents.2  Udupa K.N., and Prasad G., Biochemical and studies on the effect of cissus quadrangularis in fracture repair, lndian J. Med.  Res., 1964, 52, (5) 480-487.Udupa K. N., and Prasad G. C., Further studies on the effect of Cissus quadrangularis in acceleratingGarima Mishra et al /Int.J. PharmTech Res.2010,2(2) 1308 fracture healing, Indian J. Med. Res., 1964, 52, drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 24. आमलकी  Latin Name_Emblica officinalis Gaertn  Family :Euphorbiacea  AqÉëÑiÉÉ(ÌlÉ.AÉ):lÉ ÍqÉërÉiÉå AlÉrÉÉ CÌiÉ If it is consumed,no untimely death  AÉqÉsÉÌMü(ÌlÉ.AÉ):AÉ xÉqÉÉliÉÉiÉ qÉsÉiÉå kÉÉUrÉÌiÉ UxÉÉrÉlÉaÉÑhÉÉlÉ CÌiÉ(full of rasayan properties)  uÉrÉxiÉÉ(pÉÉ.mÉë) ÌuÉëwrÉÉ(pÉÉ.mÉë)  Chemical Content  Hydrolyzable tannins  Emblicanin A,B  Ellagic acid(inhibits the mutation of genes and reduce chromosomal abnormalities. AÉqÉsÉMüÐ uÉrÉxiÉÉmÉlÉÉÇ(cÉ.xÉÑ25/40) ÌlÉirÉ xÉåuÉÌlÉrÉ SìurÉ(cÉ.xÉÑ 5/12) AÉqÉsÉMüÐ cÉÑhÉï:uÉwÉïzÉiÉqÉ AeÉUÇ(cÉ.ÍcÉ1/1/8) U£üÌmÉ¨É mÉëqÉåWûblÉ mÉUÇ ÌuÉëwrÉ UxÉÉrÉlÉ (pÉÉ.mÉë) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 25. Research   The fruits extracts of Emblica officinalis (Amla) has been reported to have strong anti-oxidant properties.. Chromium (Cr), an immunosuppressive agent results in enhanced cytotoxicity, free radical production, lipid peroxidation and decreased glutathione peroxidase (GPx) activity and diminished glutathione (GSH) levels. There was a significant inhibition concanavalin-A-stimulated lymphocyte proliferation. Chromium also inhibited Con A .Amla significantly inhibited Cr-induced free radical production and restored the anti-oxidant status back to control level. Amla also inhibited apoptosis and DNA fragmentation induced by Cr. Interestingly, Amla relieved the immunosuppressive effects of Cr on lymphocyte proliferation and even restored the IL-2 and γ-IFN production considerably. Ram, M. Sai, et al. "Cyto-protective and immunomodulating properties of Amla (Emblica officinalis) on lymphocytes: an . in-vitro study." Journal of Ethnopharmacology 81.1 (2002): 5-10. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 26. आरग्िधैः L.N: Cassia fistula Linn Family:Leguminoseae AÉUauÉkÉ(ÌlÉ.AÉ);AÉUaÇ UÉåaÉxÉÇMüÉqÉÌmÉ WûÎliÉ it eliminates the diseases with mere doubt AÉUuÉåiÉ- AÉ UåuÉrÉÌiÉ ÌlÉÈxÉÉUrÉÌiÉ qÉsÉqÉ xÉÉUYiuÉÉiÉ. It acts as laxative. MÑü¸xÉÑSèlÉ(Ra.Ni), euÉUÉliÉMü(sodhal) AÉqÉWûÉ(shodhal), urÉÉÍkÉbÉÉiÉ(K.N) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 27.  आरग्िधे िा ियसा मृद्िीकानाां रसेन िा। त्रििृिाां िायमाणाां िा ियसा ज्िररिैः विबेि् ।। (च.चच. 3.232) Aragwadha with milk and grape juice alleviates jwar. आरग्िधथय ििाणण आरनालेन िेषयेि् । दद्रुककर्ििकु ष्ठातन हच्न्ि भसध्मानमेि च ।। (बां.से.कु ष्ठ.63) Leaves of aragwadha pounded with sour gruel and applied on the part of ring worm,kitibha,kustha,sidhma . आरग्िधथय ििाणण िृष्िातन किुिकलिैः । आमघ्नातन नरैः कु यािि ् सायां िक्िािृिातन च ।। (िा.प्र.चच.26.52) Leaves of aragvadha fried with mustard oil and taken in evening followed by meal.It alleviates ama. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 28. Research The plant contains more or less same components such as saponin, triterpenoids, steroids, glycosides, anthraquinone, flavonoids, gum, mucilage, proteins and aminoacids. From the above results, the activity of hydroalcoholic extracts of C. fistula shows significant antibacterial and antifungal activity. The chloroform extracts, whose purity level is good as compared to hydroalcoholic extract and porosity is lower than hydroalcoholic extract, found to be more active against fungal strains. Results shows that this plant is rich in tannin and phenolic compounds have been shown to possess antimicrobial activities against a number of microorganisms. In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts N. R. Bhalodia, P. B. Nariya,1 R. N.Acharya,2 andV. J. Shukla3 drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 29. इङ्गदी Latin name:Balanites aegyptica L.Delie Family:Simarubaceae ChaÉÑÌS(Ni.Adrsha): CaÉqÉ MÑü¸pÉÑiÉaÉëWûÉÌSlÉÉzlÉqÉ It removes the dosas and cures conditions like kustha ÌuÉwÉÎblÉ(sodhal):Antipoisonous  MüÉzrÉmÉ-ÍzÉzrÉÉåmÉlÉrÉlÉ xÉÇxMüÉU xÉÑ´ÉÑiÉ-UÉåqÉxÉÉiÉlÉ(xÉÑ.ÍcÉ1/108) cÉUMü-mÉëxÉÑiÉÉaÉëÑëWû(cÉ.zÉÉ8/34) कु ष्ठेषु हितान्यािुChaÉÑÌSस्तैलम् (च.हच.7.119) मूवषकविषे भशरीषेङ्गदकलकन्िु भलह्यात्ति समाक्षक्षकम ् । (सु.क.7.12) Ingudi fruit kalka with shirish and honey useful in Rat poisoning. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 30. Research Alcoholic extracts fruit of B. aegyptiaca have remarkable antimicrobial potential and thus can be used to derive antimicrobial agents especially against S. aureus, E. coli,S. typhi and S. paratyphi A. Hence, it can be used in the treatment of enteric fever, diarrhea, wound infections and urinary tract infections. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 31. इन्द्रिारुणी Latin name:Citrullus colocynthesis Linn Family name: Cucurbitaceae ClSìèuÉÉÂÍhÉ:ClSìÉ zÉÌ£üxÉqmÉlÉÉï uÉÉÂÍhÉ eÉsÉUåcÉÌlÉ. ÌuÉzÉÉsÉÉ(ÌlÉ.AÉ): ÌuÉzÉåwÉåhÉ zsÉÌiÉ- cÉsÉÌiÉ MüÉqÉsÉÉÌSUÉåaÉiÉÌlÉuÉUÉÌrÉiÉÑ It spreads all over body to cure the conditions like jaundice etc. ÌuÉwÉÎblÉ:(xÉÉå):ÌuÉwÉqÉ WûÎliÉ र्हिा गिाक्षी सगुडा च शुण्ठी (सु.उ.44.30) Indravaruni mixed with jaggery & shunthi useful in kamala. ccc cÉUMü qÉÑÍsÉÌlÉ(xÉÑ/1/77,ÌuÉUåcÉlÉ(xÉÑ/2/9) xÉÑ´ÉÑiÉ AkÉÉåuÉÉaÉWûU(xÉÑ.xÉÑ.39/4) Colocynthin acts as gastrointenstinal irritant,produces abdominal pain,watery stool drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 32. ESÒqoÉU Latin Name: Ficus glomerata Roxb.  Family Name:Moracea  ESÒqoÉU(pÉÉ.mÉë): ESÒqoÉsÉ mÉë¢Ñü¹oÉsÉMüU CirÉijÉï The ripe fruit eaten promotes strength to body.  qÉsÉrÉÑ:(ÌlÉ.AÉ): qÉsÉqÉ ÍµÉ§ÉqÉ ÌlÉWûÎliÉ.(It cures leucoderma.).  (Kakudumbar:ficus hispida) 1st Brahmarasayan Patra-udumbar (ch.chi1/1/57) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 33. एरण्डैः Latin Name:Ricinus communis Linn Family:Euphorbiacea LUhQû:(pÉÉ.mÉë): LUrÉÌiÉ uÉÉrÉÑqÉ CÌiÉ uÉÉiÉÉËU (R.N);uÉÉiÉxrÉ AËU zɧÉÑ lÉÉzÉMüÉå CÌiÉï zÉÑsÉzɧÉÑ:(Sa.Ni) cÉUMü:uÉëÑwrÉuÉÉiÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/0) xÉÑ´ÉÑiÉ:AkÉÉåuÉÉaÉWûU(xÉÑ.xÉÑ.39/4) U.U.xÉ/pÉÉ.mÉë:AÉqÉuÉÉiÉ P.V Sharma_vedanasthapan LUhQû zÉÉåTüzÉÑsÉblÉ ÌuÉëwrÉ uÉÉiÉWûUÇ mÉUÇ(UÉ.ÌlÉ) The mechanism of analgesic effect of ricinolic acid could probably be due to inhibition of the effect of endogenous substances that induces pain at nerve endings similar to that of NSAIDs. r, 1,* ÌuÉश्व्ेरण्डजं ्ूलं क्वाथपयत्वा जलं पिबेत प ंगुसौवर्धलोिेतं सद्यिः शूलपनवारण् (भा.प्र.पर्.30.57) One should take decoction of shunthi,root of errand, hingu & rock salt, gets instant colic relief drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 34. Research Central analgesic activity: The crude extract of root bark of R. communis possesses central analgesic activity in tail flick response model to radiant heat at a dose of 250mg/kg. The ethanolic extract of pericarp of root bark of R. communis possesses typical CNS stimulant and neuroleptic effects. The stimulant effects, such a exophthamus, hyperreactivity (evidenced by tremors or by the pinna and grip-strength reaction), memory improvement and clonic seizures, seem to be due to the presence of the alkaloid ricinine. On the other hand,compounds other than ricinine may be responsible for the neuroleptic- like effects of the extract,because ricinine did not cause reduction of locomotor activity or catalepsy in the mice. Ferraz A.C., Angelucci M.E.M., Da Costa M.L., Batista I. R., De Oliveira B.H. and Da Cunha C. Pharmacological Evaluation of Ricinine, a Central Nervous System Stimulant Isolated from Ricinus communis. Pharmacology Biochemistry and Behavior1999; Vol. 63: No. 3: 367–375. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 35. MüOÒûMüÉ  L.N: Pichrohiza Kurroa Royle ex. Benth F.N- SCROPHULARACEAE  MüOÒûMüÉ(pÉÉ.) MüOûÌiÉ UÉåaÉqÉ ÌuÉëhÉÉÌiÉ CÌiÉ It engulfs the diseases.  AËU¹(kÉ.ÌlÉ):lÉ ËU¹qÉÉzÉÑpÉxrÉ  AÉqÉÎblÉ(kÉ.ÌlÉ) it pacifies the ama. अम्लवित्ते  किुकाभसिा ऽिलेह्या ििोलविश्िां च क्षौद्रसांयुक्िम ्(िृ.मा.53.14) ÌlÉrÉÌiÉ MüÉÍsÉMü euÉU-pÉÉ.ÌlÉ वित्तज्िरघ्नी किुका श्र्लेक्ष्णविष्िा सशकि रा । (अ.सां.चच. 1.76) cÉ cÉUMü:sÉåZÉÌlÉrÉ,pÉåSÌlÉrÉ xÉÑ´ÉÑiÉ:qÉÑxiÉÉÌS,mÉOûÉåsÉÉÌS-AÉqÉÌiÉxÉÉUlÉÉzÉlÉqÉ ÌuÉzÉåwÉÉiÉ SÉåwÉmÉÉcÉlÉ ÌmÉë.zÉ-ÌmɨÉÌuÉUåcÉMü M.C of Arogyvardhini Total use-28 diseases(B.R) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 36. Research Iridoid glycosides like kutkin, Picroliv, Picrisides I, II, III&IV,Kutkosides are the chemical moieties that may be responsible for Antipyreticactivity. Ghisalberti E.L, Biological and Pharmacological activity of naturallyoccurring Iridoids and Secoiridoids,Phytomedicine 5, 147-163, 1998.drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 37. MühOèMüÉËU  Latin name-Solannum surattens Burm f  Family:Solanacea  MüÉxÉÎblÉ(pÉÉ.)  SìÉuÉÍhÉ:(A.ÌlÉ) zsÉåwqÉÉhÉÉqÉ SìÉuÉrÉÌiÉ  (MüTü ÌlÉxÉÑSlÉqÉ xÉÑ.xÉÑ,38)  urÉÉÍbÉ((pÉÉ.)ë:urÉÉÎeÉbÉëÌiÉ aÉlkaÉëWûhÉqÉ MüUÉåÌiÉ  It improves olfactory function (Bapal Vaidya) ÌlÉÌSÎakÉMüÉ(ÌlÉ.AÉ)-ÌlÉiÉUÉqÉ ÌS½iÉåxqÉ,EwlÉiuÉÉÌS aÉÑhÉå CÌiÉ Owing to its ushna tikshna ,it spreads all ovder body easily,alleviates diseases. Major chemical constitutes: BCarotene,Disgenin, Solanocarpine(Solanine-S), Tomatidienol etc. Charaka Kasahara Hikkanigrahana Kanthya A.H:MüÉxÉåÌlÉÌSÎakÉMüÉ(A.¾û.E ) ÌmÉë.ÌlÉ-MüÉxÉWûU िीनसे ;व्याघ्रीतैल् (शा.सं.2.9.180) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 38. Gautam et al. 2008 studied effects of Solanum xanthocarpum extract on some of the parameters like smooth muscle relaxation, and antagonism of asthma mediators such as histamine, eiosinophils and protection against mast cell degranulation which seemed to be prominent in pathophysiology of asthma. Further they showed that ethanol extract of Solanum xanthocarpum shown a significant antihistaminic activity in histamine induced contractionin goat tracheal chain preparation.Thus, the significant inhibition of histamine induced contractions produced by ethanol extract of Solanum xanthocarpum flower on isolated goat tracheal chain preparation indicates that the Solanum xanthocarpum flower has antihistaminic (H1- receptor antagonist) action.While screening the all three extracts of flowers of Solanum xanthocarpum, results were indicative that only ethanolic extract of Solanum xanthocarpum at a dose of 50 and 100 mg / kg reduced milkinduced eiosinophilia of statistical significance. Solanum xanthocarpum at a dose of (50- 100 mg/kg, i.p) showed significant mast cell stabilization as compared to standard drug Disodiumchromoglycate (DSCG). Vadnere GP, Gaud RS, Singhai AK; Evaluation of Anti-Asthmatic Property of Solanum Xanthocarpum Flower Extracts. Pharmacology online, 2008; 1: 513-522. कण्टकारीरसे पसद्धो ्ुद्गयूषिः सुसंस्कृ तिः सगौरा्लकिः सा्लिः सवधकासपभषपग्जत् (र्.पर्. 18.184) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 39. MüÌmÉMücNÒûBotanical name: Mucuna pruriens Hook. Family: Fabaceae  MühQÒûUÉ(pÉÉ.)  ÌuÉëwÍpÉ((pÉÉ.)  ÌuÉëzrÉÌuÉeÉÉ(kÉ.ÌlÉ) Charak;Valya mahakashya(ch.su 4/7) Vrihmani gutika,apatyakar swaras-vajikara(ch.chi) Amritprasghreet,2nd sarpiguda-kshatkhina(ch.chi 11 Sarangdhar:Vajikar dravya Mucuna Pruriens L Dopa crosses BBB,decarboxylated & converted into Dopamine. L-Dopa DOPAMINE INHIBITS PROLACTIN AND PRESERVES TESTOSTERONE Deficiency of L Methyl Dopa causes Parkinsonism. Kapikachu D.O.C IN Parkinsonism % of L-DOPA at Velvet Bean Outer Pericarp:3-6% Endocarp:5.3% ADR GastricUpset,Breathlessn es,Insomnia,Headache, Local irritation drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 40.  Methanolic extract of Mucuna pruriens seed was tested for their possible androgenic activity in Wistermale albino rats. The methanolic extract of M. pruriens plant was gavaged separately into 2 group of ratat similar doses of 1000 mg/kg b.wt and 1500 mg/kg b.wt for 30 days. At the end of the treatment, the animals were killed and the blood, testis, epididymis, seminal vesicles and prostate were collected for biochemical analysis. The methanolic extracts of M. pruriens significantly increased the relative weight of the testis, serum and testicular testosterone level, protein level in the testis and epididymis, and epididymal alkaline phosphatase activity. The methanolic extracts of M.pruriens possess androgenic activity. Evaluation of androgenic activity of Mucuna pruriens in male rats K. Muthu1* and P. Krishnamoorthy2 वानरी वपटका (भा.प्र.पर्.72.71-75) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 41. MüÎqmÉssÉMü  UåcÉlÉ(pÉÉ.mÉë)  U£üzÉqÉlÉ(Måü.ÌlÉ)  UÉåcÉlÉMü(Måü.ÌlÉ)  uÉëhzÉÉåkÉlÉ(Måü.ÌlÉ) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 42. Ethanolic extract of Mallotus philippinensis fruit (200 mg/kg) was administered orally, once daily for 10 days .MPE was found safe when given to rats upto 10 times of optimal effective dose. Mallotus philippinensis has been tested in-vitro for wound healing activity by examining the proliferation, migration of mesenchymal stem cell by secreting various cytokines to wounded site from bone marrow to systemic circulation and finally remodel wounded tissues Mallotus philippinensis Muell. Arg fruit glandular hairs extract promotes wound healing on different wound model in rats BMC Complementary and Alternative Medicine Sampledoi:10.1186/s12 drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 43. MÑÇüMÑüqÉ  L.N:Crocus Sativus Linn  F.N:Iridaceae  MÑÇüMÑüqÉ:MÑüYrÉiÉå AÉÌSrÉiÉå ÍzÉUÉåÂaÉ uÉëhÉÌSlÉÉzÉlÉjÉï  It is used in headache,wound etc.(ni.adarsh)  uÉhrÉïqÉ(pÉÉ.mÉë) Excess intake of saffron at pregnancy might cause contraction of uterus leading to possible miscarriage. Headache,Anxiety,Skin allergies,Dryness of mouth Stomach upset if saffron taken more. शकध राकु ङक्श्रृतं घृतं पित्तासृगन्वये (अ.हृ.उ.24.7) Headache caused due to pitta=rakta to be aleeviated with intake of snuff of ghee cooked with sarkara and kumkuma drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 44. MÑüOûeÉ zÉ¢ü:zÉYlÉÉåÌiÉ CÌiÉ AÌiÉxÉUÉÌS UÉåaÉÉlÉ (ÌlÉ.AÉ) xÉlaÉëÉÌWû:mÉÑËUwÉqÉ xÉlaÉëÉëWûÌiÉ mÉÑÇMÑüOûeÉ Îx§ÉMÑüOûeÉ (H.antidysenterica) (Wrightia tomentosa) ÌuÉëWûiÉ TüsÉ zrÉÉqÉ µÉåiÉmÉÑwmÉ TüsÉÌuÉëliÉ AhÉÑ ÎxlÉakÉmÉ§É AÂhÉmÉÑwmÉ ÌiÉ£ü UxÉ qÉkÉÑU Acharya Dalhan strictly opines that pum kutaj to be used in the management of Atisara(Diarrhoea) Charak Arshoghna,Kandughna MÑüOûeÉiuÉMü zsÉåwqÉÌmÉiÉU£üxÉÉÇaÉëÉÌWûMüÉåmÉzÉÉåwÉÉhÉÉqÉ (cÉ.xÉÑ25/40) Isolated use of Kurchicine as antidiarrhoel is not safe as Kutajghanvati in atisaradrrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 45. H. antidysenterica produces gastrointestinal tract stimulation by activation of histamine receptors and relaxes the gastrointestinal tract by Ca++ channel blockade, which provided the basic ground for its usefulness in gut motility problems such as constipation, colic and diarrhea [8]. The alkaloid conessin posseses Ach inhibitory activity and act as antidiarrhoeal. The present study concludes that ethanolic extract of H. antidysenterica seeds is effective against noninfectious as well as infectious diarrhea as it possesses antimicrobial and antidiarrheal property. Evaluation of antidiarrheal activity of ethanolic extract of Holarrhena antidysenterica seeds in rats Dushyant Kumar Sharma, Vinod Kumar Gupta, Surendra Kumar, Vet World. 2015 Dec; 8(12): 1392–1395drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 46. MüÉåÌMüsÉÉ¤É  L.N:Asteracantha longifolia  F.N:Amaranthaceae  AkrhQû  msÉÏWûzɧÉÑ(ÌlÉ.AÉ)  CZÉÑU uÉÉiÉU£üÉqÉuÉÉiÉÎeÉiÉ zÉÑ¢üuÉkÉïlÉ (zÉÉå.ÌlÉ) drrout.sibaprasad@gmail.com,24/06/2016 Friday वातरक्ते कोपकलाक्षा्ृताक्वाथे पिबेत कृ षणां यथाबल् िथ्यबोजी पिसप्ता ान ्ुच्यते वातशोपणतात (र्.द.39.23) वाजीकरणे स्वयंगुप्तेक्षुरकयोिः फलर्ूणं सशकध र् धारोषणेन नरिः िीत्वा ियसा न क्षयं व्रजेत (सु.पर्.26.33) cÉUMü zÉÑ¢üzÉÉåkÉlÉ,qÉkÉÑUxMülS xÉÑ´ÉÑiÉ uÉÉÎeÉMüU(xÉÑ.ÍcÉ.26/38)
  • 47. Research:  The ethanolic extract of seeds of A. longifolia was administered to groups of rats in 100, 150 and 200 mg kg⁻¹ doses for a period of 28 days, and the action compared with control rats. The ethanolic extract exhibited pronounced anabolic effects in treated animals, as evidenced by gains in the body and reproductive organ weights. Increased spermatogenesis due to treatment with extracts was also witnessed in transverse section. The treatment further markedly affected sexual behaviour of the animals, as reflected by the reduction of ML, increase in MF and enhanced attractability towards females. A significant increase in the sperm count as well as fructose levels of seminal vesicles was noted.  Effect of Asteracantha longifolia seeds on the sexual behaviour of male rats. Chauhan NS1, Sharma V, Dixit VKNat Prod Res. 2011 Sep;25(15):1423-31. doi: 10.1080/14786410802588493. Epub 2011 Jul 8. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 48. ZÉÌSU  L.N:Acacia catechu  F.N:Mimosaceae  MÑüwPèblÉ(pÉÉ.)  aÉsÉUÉåaÉÌlÉëiÉ(xÉÉå)  SliÉkÉÉuÉlÉ(pÉÉ)  qÉåSÉåblÉ(xÉÉå)  uÉëhzÉÉåkÉlÉ(UÉ.ÌlÉ) व्रणशोधने(cÉ.ÍcÉ.25/84) त्रिफला खर्दरो दािी न्यग्रोधार्दबिला कु शैः। (च.चच.199-206) तनम्बकोलकििाणण कषायाैः शोधनाैः मिाैः । मुखरोगे;खदिरादिगुडिका, Heartwood is used to yield concentrated aqueous extract i.e. Cutch and Katha. The cutch and Katha (extract) possess astringent, cooling and digestive properties; and is commonly used in throat, ulcers by reducing inflammation etc The Pharma Research (T. Ph. Res.), (2011), 5(2); 273-293 ACACIA CATECHU WILLD–A GIFT FROM AYURVEDA TO MANKIND” – A REVIEWLakshmi.T , Anitha Roy Use of Acacia catechu C.I in breast feeding. Side Effect:Hypotension खर्दरथय ििा क्िािो यिाlÉÏक्िाि एि च क्िािश्र्च तनम्बमूलथय दन्िरोगतनिारणैः ।। (हा.सां.3.46.14) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 49. Research  Significant reduction of blood glucose level was observed in non diabetic albino rats following single dose treatment with the test drug at a dose of 500 mg/kg, p.o. ( P <0.01). Significant reduction of blood glucose level was also evident in diabetic rats at doses of 250 and 500 mg/kg ( P <0.001). In the present study, preliminary phytochemical screening of Acacia catechu found the presence of flavonoids and reports substantiate the presence of catechutanicacid, quercetin,catechin,pseudotannin,phlabotannin,polypheno ls, epicatechin and cyanidanol compounds in A. catechu . The antimicrobial and hypoglycaemic properties of Acacia catechu may be described to the presence of flavonoids, It is thought that catechu may contain chemicals that can decrease inflammation and kill bacteria. which have been shown to inhibit cyclooxygenases and promote β-cell regeneration besides having insulin secretagogues and antioxidant properties. Antipyretic, antidiarrhoeal, hypoglycaemic and hepatoprotective activities of ethyl acetate extract of Acacia catechu Willd. in albino rats D Ray1, Kh. Sharatchandra2, IS Thokchom3 drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 50.  Active constituent Tannins Acts topically as astringent to mucosal surfaces and following oral ingestion it consequently get hydrolyzed and alter the fluidity of the bowel contents (so used in anti-diarrheal remedies) .They are also attributed with anti-hemorrhagic, anti-inflammatory and antacid properties. Catechin Have significant antioxidant and antimicrobial effects. It is considered to be the best antioxidant Flavonoids Increase secretion of insulin and inhibit cycloxygenase and lipoxygenase .Thus it possesses anti diabetic and anti-inflammatory effect.  Taxifolin Potent Antibacterial agent. Noreen et. al; Planta Medica 64, 1998; United States. 29.Hocking D. 1993. Trees for Drylands. Oxford & IBH Publishing Co. New Delhi. drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 51. aÉÑaaÉÑsÉ  L.N: Commiphora mukul  F.N :Burseraceae  mÉsÉlMüwÉÉ(pÉÉ):mÉsÉÇ qÉÉÇxÉÇ ÌWûlÉÉÎxiÉ AÌiÉ sÉåZÉlÉiuÉÉiÉ  aÉÑaÉÑsÉ(ÌlÉ.AÉ):aÉÑQûÌiÉ U¤ ÌiÉ uÉÉiÉUÉåaÉÉiÉ  xÉ lÉuÉÉå ÌuÉë¼hÉ ÌuÉëwrÉ mÉÑUÉhÉ iÉÑ AÌiÉsÉåZÉlÉqÉ(pÉÉ.mÉë) रसाञ्जनस्य ् तिः िञ्र््ूलस्य गुग्गुलोिः पशलाजतुप्रयोगश्च सपग्न्न्थरसो प तिः (अ.हृ.सू.14.23) ्ेदोऽपनले गुग्गुलुिः (अ.हृ.उ.40.48) स्थौल्ये drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 52. Research  Several possible mechanisms have been proposed for hypolipidemic activity of guggulsterone. cholesterol 7α-hydroxylase (CYP7A1) the rate- limiting enzyme in the classic pathway of bile acid synthesis from cholesterol in the liver (he expression of CYP7A1 is negatively regulated by bile acids through a negative feedback circuit involving Conversion of cholesterol to bile acids and subsequent excretion through the enterohepatic circulation represent a major pathway to remove excessive cholesterol from the body (Russell 2003). The is several nuclear receptors including bile acid sensor FXR, liver receptor homolog 1 (LRH-1), Recent studies have established that guggulsterone is an FXR antagonist has been suggested as a mechanism for the cholesterol-lowering effect of guggulsterone  Bile acid sensor(FXR)-Liver receptor homolog(LRH1)-Small heterodiametre partner-cholesterol 7 alpha hydroxylase Russell 2003; Fuchs 2003). T(Urizar et al. 2002; Wu et al. 2002) (Urizar et al. 2002) (Lu et al. 2000; Goodwin et al. 2000; Davis et al. 2002) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 53. aÉÑQÒûÍcÉ  aÉÑQÒûÍcÉ(Bh.P): aÉÑQûÌiÉ UZrÉÌiÉ CÌiÉ aÉÑQû UZÉhÉå  It protects the body against various diseases.  euÉUlÉÉÍzÉÌlÉ(xÉÉå)  UxÉÉrÉÌlÉ(pÉÉ)  uÉrÉxjÉÉ(pÉÉ)  ÌuÉwÉÎblÉ(pÉÉ)  aÉÑQÒûÍcÉ euÉU pÉÑiÉÎblÉ uÉÍsÉmÉÍsÉiÉlÉÍzÉÌlÉ(zÉÉå) uÉrÉxiÉÉmÉlÉ,SÉWûmÉëzÉqÉlÉ(cÉ.xÉÑ4) xÉuÉïeuÉUWûU(pÉÉ.mÉë) AqÉëÑiÉÉxuÉUxÉ-ÎeÉhÉïeuÉUWûU(zÉÉ) euÉU SÉWû lÉÉzÉlÉ(rÉÉå.U) पवष्ज्वरे:पिफलायािः कषायं वा गुडूच्या रस्ेव वा (र्.पर्.3.299) रसायने (र्.पर्.1/3/31) मण्डूकण्यायाः स्वरसाः प्रयोज्याः क्षीरेण यष्टीमकुकस्य चूणयम् रसो गुडूच्यास्तु समूलपुष्पयााः कल्काः प्रयोज्याः खलु शंखपुष्पयााः L.N:Tinospora cordifolia,(Willd) F.N: Menispermaceae , xÉÑ´ÉÑiÉ: uÉåÎssÉiÉMü xÉÏuÉlÉ(xÉÑ.xÉÑ.25/21) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 54. Research Enhanced lysozyme production was reported at different time intervals  Ethanolic extract of stem and leaves of T.Cordifolia exhibits the significant antipyeretic activity(vedavathy ,rao)  Int J Ayurveda Res. 201 0  Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) – validation of the Ayurvedic pharmacology through experimental and clinical studiesAvnish K. Upadhyay, Kaushal Kumar,1 Arvind Kumar,2 and Hari S. MishraAudrrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 55. aÉÉåZÉÑU  L.N:Tribullus terestriss(Zygophallaceae)  mÉsÉlMüwÉÉ(pÉÉ):mÉsÉÇ qÉÉÇxÉÇ ÌWûlÉÉÎxiÉ AÌiÉ MÇüOûÌMüiuÉÉiÉ cÉUMü qÉѧÉÌuÉUåcÉÌlÉrÉ,zÉÉåjÉWûU qÉѧɢÑüdlÉ AÌlÉsÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/40) Yatra Akrutihi, tatra gunaaha vasanti. Tribulus fruits have quite resemblance with oxalate stones of kidney and bladder Oxalate stone structure T. Fruit Interesting Fact drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 56. Research  Anti-cholestrolemic effect: Saponin fraction of dried root, administered by gastric intubation to rabbits decreased the development of protein, carbohydrate, lipid dystrophy of the liver vs cholesterol loaded animals. [12]  Hypoglycemic and hypolipidemic effects: The extract of both T alatus and T terrestris significantly decreased the blood glucose levelsin diabetic rats. [29] drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 57. cÉ¢üqÉSï L.N:Cassia tora f.n: Caesalpinacea MÑü¸WûÉ(pÉÉ.mÉë) SSìÓblÉ(pÉÉ.mÉë) mÉÉmÉbÉÉÌiÉ(xÉÉ Kharjughna(Dh.Ni) चक्रमदिकबीजातन जीरकां च समाांशकम ् । थिोकां सुदशिनामूलां दद्रुकु ष्ठविनाशनम ् ।। (बां.से.कु ष्ठ.67) Seed paste with jeerak and sarkara in equal quantity is applied externally in eczema,leprosy, tinea, allergic dermatitis, psoriasis, å) Eng.Name: Ring worm plant Dadrukanduhara, Kantikara:Dh.Ni drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 58. Research  The major antifungal compound was identified as chrysophanic acid-9-anthrone, the structure of which was assigned on the basis of its chemical properties and uv, ir, nmr and mass spectral analysis. The compound was active against Trichophyton rubrum, T. mentagrophytes, Microsporum canis, M. gypseum and Geotrichum candidum.Opportunistic diseaseas. Isolation of chrysophanic acid-9-anthrone, the major antifungal principle of Cassia tora. Acharya TK, Chatterjee IB drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 59. ÍcɧUçMü  Vahnikrut(xÉÉå) – Improves digestion strength Pachana (pÉÉ.mÉë) digestive Laghu (pÉÉ.mÉë)– light to digest Kushtahara(cÉ) – useful in skin diseases AlÉsÉ(pÉÉ.mÉë)  ÌSmÉlÉ(pÉÉ.mÉë)  ÌSmrÉMüÉ(pÉÉ.mÉë) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 60. ÎeÉuÉliÉÏ  L.N: Leptadenia reticulate(Retz.)  F.N: Asclepiadaceae  aÉU¾èiÉ  ÎeÉuÉuÉÍkÉïlÉÏ(xÉÉå);ÎeÉuÉÇ mÉëÉhÉzÉÌ£ü uÉkÉïrÉÌiÉ CÌiÉ  uÉsÉuÉÍkÉïÌlÉ(xÉÉå)  mÉëÉhÉSÉ:(UÉ);mÉëÉhÉzÉÌ£ü SSÉÌiÉ CÌiÉ cÉUMü: uÉrÉ:xiÉÉmÉlÉ, eÉÏuÉlÉÏrÉ,qÉkÉÑUxMülS A.¾û:eÉÏuÉlÉÏrÉ mÉÇcÉqÉÑsÉ(A.¾Òû.xÉÑ15/8) Måü.ÌlÉ:xÉuÉïSÉåwÉblÉÏ uÉsrÉÉ ÌuÉëwrÉÉ UxÉÉrÉlÉÏ drrout.sibaprasad@gmail.com,24/06/2016 Friday पवषे तण्डु लीयकजीवन्तीवाताधकु सुपनषण्णकािः र्ुच्र्ू्धण्डूकिणी र् शाकञ्र् कु लकं प त् , , (र्.पर्.23.225)
  • 61. Reported research Activity  Anticarcinogenic ,Activity of Leptadenia reticulata against Dalton’s Ascitic Lymphoma  L. Sathiyanarayanan, Sinnathambi Arulmozhi, N. Chidambaranathan  antifungal.,  antioxidant,  cardioprotective. galactogogue drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 62. ̧ÉuÉëÑiÉ L.N:Operculina turpethum(L.) CONVOLVULACEAE ÌlÉzÉÉåjÉ(pÉÉ):ÌlÉuÉÉUrÉÌiÉ zÉÉåjÉ UåcÉlÉiuÉÉiÉ UåcÉlÉÏ(pÉÉ) xÉUhÉÉ(A.ÌlÉ) ̧ÉuÉëÑiÉxÉÑZÉÌuÉUåcÉlÉÉlÉqÉ(cÉ.xÉÑ.25/40) pÉåSlÉÏrÉ qÉWûÉMüwÉÉrÉ(cÉ,xÉÑ 4/4) ÌuÉUåcÉlÉå ̧ÉuÉëÑiÉqÉÑsÉqÉ ´Éå¹qÉ(cÉ.Mü.7/1) xÉÑ´ÉÑiÉ:AkÉÉåpÉÉaÉWûU(xÉÑ.xÉÑ.39/3) xiÉoSÉÌlÉ,xÉÑmiÉÉÌlÉ,AxuÉåSÉÌlÉ,MühQÒûsÉÉÌlÉ MÑü¸: ̧ÉuÉ×iÉ(cÉ.ÍcÉ 7/57) zÉÉåTümÉÉhQèuÉÉqÉrÉ msÉÏWûÉlÉ WûÎliÉ ´Éå¸Éå ÌuÉUåcÉlÉå (kÉ.ÌlÉ)å drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 63. Anti-inflammatory activity- An experimental study was carried out(Rajashekar M et al; 2006) to evaluate the effect of oral administration of root powder of O. turpethum and its polyherbal formulation Avipattikar churna on rat paw edema in albino rats. Results indicated that pretreatment with the root powder of O. turpethum and Avipattikara churna (100 mg/kg body weight)reduced the formalin induced edema volume tothe extent of 36.45% and 27.11%respectively. Rajashekar M. Bhande, Laakshmayya,Pramod Kumar, Nitin K. Mahurkar, & S.Ramachandra Setty, Pharmacological Screening of Root of OperculinaTurpethum and its Formulations. Acta Pharmaceutica Sciencia, 48: 11-17, (2006).drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 64. SÉÂWûËUSìÉ  Botanical name – Berberis aristata Dc., Family – Berberidaceae Ì¢üÍqÉWûUÉ(xÉÉå) mÉÇcÉmÉÇcÉÉ(pÉÉ): mÉÉMüÉlÉliÉUÇ mÉcÉÌiÉ kÉÉiÉÑmÉÉMÇü MüUÉåÌiÉ rÉ¢ÑüiÉ E¨ÉåeÉMü MüUÉåÌiÉ cÉ ÌuÉzÉÉåÍkÉlÉÏ(Måü.ÌlÉ) SÉuÉÏïï iuÉcÉÇ MüsMåülÉ mÉëkÉÉlÉÇ uÉëhÉUÉåmÉhÉqÉ (cÉ¢üS¨É) drrout.sibaprasad@gmail.com,24/06/2016 Friday व्रणे दुवाधस्वरसपसद्धं वा तैलं कप्िल्लके न वा दावीत्वर्श्च कल्के न प्रधानं व्रणरोिण् (र्.पर्.25.93)
  • 65. Research  The main constituents of root were identified as berberine, berbamine and palmatine through HPTLC. The extract besides being safe, lowered the blood glucose significantly without any hypoglycemic effect on their control counterparts. It increased CAT, SOD, GPx, GR activity significantly and reduced lipid peroxidation (41.6%) and protein carbonylation (30.15%). It also increased the glucokinase and glucose- 6-phosphate dehydrogenase activities Thus, the extract of Berberis sristata (root) has strong potential to regulate glucose homeostasis through decreased gluconeogenesis and oxidative stress. Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats Jyotsna Singh, Poonam Kakkar drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 66. The aqueous root extract of Berberis aristata showed good hepato protective activity when administered at doses of 10mg/kg and 20 mg/kg; i/p and the effects were dose dependent. Serum ALT, AST, ALP activities significantly decreased in a dose- dependent manner The present study demonstrates that berberine possesses hepatoprotective effects against CCl4-induced hepatotoxicity and that the effects are both preventive and curative. HEPATOPROTECTIVE ACTIVITY OF BERBERISARISTATA ROOT EXTRACT AGAINST CHEMICAL INDUCED ACUTE HEPATOTOXICITY IN RATS Navdeep Dehar, Rani Walia, R.BVerma, Pinky Pandeydrrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 67. SìɤrÉÉ L. n – Vitis vinifera Linn Family-Vitaceae uÉëÑÇWûÍhÉ(Mãü.ÌlÉ) rɤqÉÎblÉ(zÉÉå.ÌlÉ) ´ÉqÉÉmÉWûÉ(pÉÉ.mÉë) Resveratrol present in grapes is a very potent anti – oxidant. Grapes are rich sources of vitamin E (anti-oxidant vitamin) MüÉxÉWûU,euÉUWûU,´ÉqÉWûU qÉWûMüwÉÉrÉ(cÉ.xÉÑ4), xÉÇiÉmÉïÍhÉrÉ (cÉ.xÉÑ 23/38) TüsÉÉå¨ÉqÉÉ(cÉ.xÉÑ 25/39) uÉëÑWÇûÍhÉ ÌuÉëwrÉÉ(cÉ.xÉÑ 27/125) द्राक्षाबिल्वशिवािीनाां फलां िुष्कां गुणाचिकम् ||५१|| – Bhavaprakasha grapes with milk is best avoided (samjog virudha)(ch su 26/19) Gostani variety draksha best Draksha help to strengthen lungs. Expectoration of kapha or Phlegm achieved with the help of this fruit. Thus grapes main ingredients ayurvedic respiratory conditions like Tuberculosis, cough, bronchitis क्षयरोगे(सु.उ.41.40) द्राक्षापसता्ागपधकावले िः सक्षौद्रतैलिः क्षयरोगघाती drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 68. ÌlÉqoÉ L.N: Azadirachta indica A.Juss F.N: Meliaceae  AËU¹(pÉÉ.)lÉ ËU¹qÉzÉÑpÉqÉxqÉÉiÉ,xÉuÉïUÉåaÉlÉÉzÉMü  ¢ÑüÍqÉblÉ(Mãü.ÌlÉ)  NûSïlÉ(Mãü.ÌlÉ)  ÌmÉcÉÑqÉSï(pÉÉ.mÉë):  ÌmÉcÉÑqÉ MÑü¸qÉ qÉSïrÉÌiÉ lÉÉzÉrÉÌiÉ  mÉÑrÉÉËU(zÉ.) Charaka Samhita Kandughna(ch.su4) Tiktaskandha(ch.vi 8/143) Kusthanashak kasaya (ch.chi 7/92) Jantudagdha,Lashikaprasut kustha:Nimba-vidang pana & lepa with gomutra(ch.chi 8/157) Neem seed oil and leaf extract is spermicidal, inhibits spermatogenesis, antiimplantation,abortificient properties wchich enables to prepare contraceptive from neem oil(Sinha Et all.1984) YONI DHUPANWITH NIMBA KASTHA BEFORE VYAVAYA CONTRACEPTIVE (YOGATANAKAR) यिः खाादेदभयाररट्ररटा्लकं तथा स जयेत सवधकु ष्ठापन ्ासादूर्ध्वं न संशयिः (ग.पन.2.36.87) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 69. कक्रभमरोगे तनम्बििसमुद्िूिां रसां क्षौद्रयुिां विबेि् । धत्तूरििजां िावि कक्रभमनाशनमुत्तमम ् ।। (िा.प्र.चच.7.24) In vitro ovicidal and larvicidal activity of Azadirachta indica extracts on Haemonchus contortus  drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 70. mÉÉPûÉ  Botanical name – Cissampelos pareira Family – Menispermaceae  SÏmÉlÉÏ(UÉ.ÌlÉ)  mÉÉmÉcÉåÍsÉMüÉ(ÌlÉ.AÉ):mÉÉmÉcÉ uÉÉrÉÑ cÉåsÉrÉÌiÉ ÌlÉuÉÉUrÉÌiÉ  qÉWûÉãeÉxÉÏ(xÉÉå)  U£üÎblÉ(xÉÉå)  ÌuÉwÉWûl§ÉÏ(xÉÉå)  uÉÉåkÉÌMü(A) mÉÉPûÉ AÌiÉxÉÉUzÉÑsÉÎblÉ MüTüÌmÉiÉeuÉUmÉWûÉ  UÉeÉmÉPûÉ iÉjÉåuÉ U£üxÉÇaÉëÉÌWûÍhÉ cÉ xÉÉ(zÉÉå) Charak Sandhaniya Mahakashaya(ch.su4) M.C of Pushyanuga Churna अशधपस िाठया वा युतं तक्रं वातवर्ोऽनुलो्न् (अ.हृ.पर्.8.61) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 71. mÉÑlÉlÉïuÉÉ zÉÉåjÉÎblÉ(pÉÉ)  xɱÉåÌuÉzÉÉåÌwÉ(Måü);xÉkrÉÉå zÉÉåjÉ ÌuÉzÉÉåwÉrÉÌiÉ  xÉÉËUÍhÉ(xÉÉå)  ÌuÉwÉÎblÉ(UÉ):It is hepatoprotective and detoxifies the toxins mÉÑlÉlÉïuÉÉ zÉÉMü-ÌuÉzÉåwÉÉiÉ zÉÉåTülÉÉzlÉ(xÉÑ.E.46/255) िुननधवापन्बिटोलशुण्ठीपतक्ता्ृतादाव्यधभयाकषायिः सवाधङगशोफोदरकासशूलश्वासापन्वतं िाण्डु गदं पन पन्त (वृ.्ा.38.3) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 72. Research  Ethanol extract of leaves at dose of 400mg/kgexhibited maximum anti-inflammatory effect with30.4, 32.2, 33.9 and 32% with carrageenin,serotonin, histamine and dextran induced rat pawedema models, respectively.Ethanol extract of stembark also exhibited COX-1 and IC50value of 100ng/ml proving the drug use in thetreatment of inflammatory condition. Antiinflammatoryactivity was assessed using extract of latex of plant by using a carragenan induced inflammatory model.47 Anti-inflammatory activity of Boerhaavia  diffusa.48 Bhalla, T.N., Gupta, M.B., Sheth, P.K., and Bhargava, K.P., Antiinflammatory activity of Boerhaavia diffusa. Indian Journal of Physiology and Pharmacology 1968; 12:37 drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 73. oÉÉMÑüÍcÉ  L.N:Psoralea corylifolia  F.N:Fabaceae  uÉÉMÑüÍcÉ(ÌlÉ.AÉ):uÉÉiÉÇ MüÉåcÉrÉÌiÉ CÌiÉ  MÑü¸ÎblÉ(pÉÉ.mÉë)  qÉsÉrÉÑ(A.ÌlÉ)  zÉÍzÉsÉåZÉÉ(pÉÉ.mÉë)  ͵ɧÉÎblÉ(ÌmÉë) सोमराजीििां चूणं श्रृांगबेरसमच्न्ििम ् । उद्िििनभमदां हच्न्ि कु ष्ठमुग्रां कृ िाथिदम ् ।। (िा.प्र.चच.54.53) अवल्गुजाद बीजकषं पिबेदुषणेन वाररणा भोजनं क्षीरसपिधर्भयां सवधकु ष्ठ रं िर् (बं.से.कु ष्ठ.101) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 74. Mode of Action  The drug Bakuchi dilates the arterioles of the subcapillary plexuses, so that the plasma is increased in this area. The skin becomes red and the melanoblasts (pigment-forming cells) are stimulated. In leukoderma, melanoblasts do not function properly and their stimulation by the drug leads them to form and exudate pigments, which gradually diffuse into the white leukodermic patches. Psoralen has been found to intercalate into DNA, where they form mono- and di- adducts in the presence of long wavelength UV light and thus are used for the treatment of hypo-pigmented lesions of the skin, such as leukoderma. [57] Vaidya AD. Reverse Pharmacological correlates of Ayurvedic drug actions. Indian J Pharmacol 2006;38:311-5 drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 75. pÉssÉÉiÉMü Latin Name:Semicarpus anacardium Linn F.N: Anacardiacea Ì¢üÍqÉblÉ(UÉ) pÉÑiÉlÉÉzÉlÉ(ÌmÉë) pÉåSlÉ(xÉÉå) uÉÉiÉÉËU(UÉ) zÉÉåTüÌ¢üiÉ(pÉÉ) Charaka – Deepaneeya –Bhedaniya-Kushtaghna भल्लातकापस्थस्वरसं पवडङगाधेन संयुत् सूयधतप्तं पल ेद युक्त्या पसद्धं पक्रप्पवनाशन् . (ग.पन.2.6.39) पवषसंसृटे अञ्जने ........ िुषिं भल्लातकस्य वा (सु.क.1.71) drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 76. Evaluation of anthelmintic activity of nuts of Semecarpusanacardium The anthelmintic activity of different extracts of nuts of Semecarpus anacardium were evaluated separately on adult Indian earthworm (Pheritima posthuma). It was found that petroleum ether, chloroform extract of S. anacardium (PESA and CESA, respectively) showed better anthelmintic activities than ethanol (EESA) and aqueous (AESA) extract of it. Antimicrobial activity of Semecarpus anacardium Linn. nut extract Alcoholic extract of dry nuts of S.anacardium showed dose dependent antimicrobial activity in vitro against Aspergillus fumi gatus andCandida albicans. At 400 mg/ml concentration, growth of both the fungi was inhibited and considerable reduction in size of cells and hyphae was observed. Analgesic activity and acute toxicity study of Semecarpus anacardium stem bark extracts using mice Sharma, Kanika Shukla, Sunil DuttMehta, PoojaBhatnagar, Maheep drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 77. uÉÉxÉÉ L.N:Adhatoda vasica F.N:Acanthaceae MüTüWûÉ(xÉÉå) MüxÉlÉÉåimÉÉOèlÉ(zÉ) SliÉxÉiuÉmÉëSÉÌrÉ(xÉÉå):SliÉÉlÉÉqÉ xÉiuÉÇ uÉsÉqÉ SSÉÌiÉ ÍpÉwÉMü(pÉÉ):AlÉåMü urÉÉÍkÉlÉÉqÉ xÉÉkÉMü qÉÉiÉÉ(pÉ);qÉiÉåuÉ ÌWûiÉMüÉËUÍhÉ UÉåÌaÉhÉÉqÉ ÍpÉwÉeÉÉÇ cÉ U£üÌmÉiÉmÉëxÉÉÌSÌlÉ(qÉ.ÌlÉ) U£üqÉѧÉÎeÉiÉ(xÉÉå) uÉxÉÉÌSÌlÉ(UÉ):uÉxÉÉqÉ xlÉåWûqÉ ÌuÉlÉÉzÉrÉÌiÉ ÍxÉÇÌWûMüÉ(pÉÉ):ÌWûlÉÎxiÉ UÉåaÉÉlÉ CÌiÉ drrout.sibaprasad@gmail.com,24/06/2016 Friday शकि रामधुसांयुक्िैः के िलो िा श्रृिो ऽवि िा । िृषैः सद्यो जयत्यस्रां स ह्यथय िरमौषधम ् ।। . . . , (अ.हृ.चच.2.24-25)
  • 78.   ििोलतनम्बयष््याहृिासाजात्यररमेदसाम ् । खर्दरथय िरायाश्च िृिगेिां प्रकलिना ।। (अ.हृ.उ.22.106) Research Pure vasicine - Dhuley (1999)Marked bronchodilator activity evaluated on contracted trachea or constricted trachea bronchial tree and act as a soothing agent. drrout.sibaprasad@gmail.com,24/06/2016 Friday िासायाां विद्यमानायामाशायाां जीवििथय च । रक्िवित्ती क्षयी कासी ककमििमिसीदति ।। (िृ.मा.9.11, हा.सां.3.10.24) वासकस्वरसे िथ्या सप्तधा िररभापवता कृ षणा वा ्धुना लीढा रक्तपित्तं द्रुतं जयेत (वृ.्ा.9.22)
  • 79. Summary of Drugs As per synonyms As Per Doshaghnata Vata Aam Marutaghni:Aswagandha Aamaghni: Katuka Vatari:Erand Aamaha:Aragwadha Vatahrit:Gambhari Vatahar:Palasha Kapha Kaphadravani:Kantakari Kaphavirodhi: Maricha Kaphaha:Vasa Pitta Pittavallabha:Ativisha drrout.sibaprasad@gmail.com,24/06/2016 Friday
  • 81. As per disease Pleeha Pleehari-Aswatha Pleehashatru:Kokillakhya Pleehaghna: Rohitak Kasa Kashaghni: Kantakari Kashabhajani: Patola Kashaghni: Bibhitak Kashonaptan: Vashak Switra Switrabhaisajya: Kakoudumbar Switraghna:Vakuchi Malayu:Vakuchi Kustha Kusthaha:Aragwadh Kusthaghni:Kakoudumbar,Bakuchi Kusthaghnaa:Khadira Dadrughna:Cakramard Kusthaveri:Tuvarak On the Basis Of Diseases Krimi Kriminashini:Ajamoda Krimihara:Daruharidra Krimighna;Nimba drrout.sibaprasad@gmail.com,24/06/2016 Friday