2. SìurÉÉhÉÉÇ lÉÉqÉÂmÉÉÍhÉ aÉÑhÉMüqÉÉïÍhÉ xÉuÉïzÉ:
mÉërÉÉåaɶÉÉÌmÉ uÉhrÉïliÉå rÉÎxqÉlÉ SìurÉaÉÑhÉÇ ÌWû iÉiÉ|| (P.V Sharma)
Dravyaguna shastra is the branch deals with the properties, action &
therapeutic effects of various dravyas.
Dravyaguna
. Vigyan
GUNAKARMA VIGYAN
(PharmacoDynamics)
Gunavigyan
(Pharmacology)
Karmavigyan
(Clinical
pharmacology)
Prayog vigyan
pharmacotherapeutics
Namarupavigyan
(pharmacognosy)
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3. ï
Ì¢ürÉiÉå AlÉålÉ CÌiÉ Ì¢ürÉÉ (Sì.aÉÑ.ÌuÉ)
The element which is responsible for the action of a drug is known as
‘’karma’’
Ì¢ürÉÉ sɤÉhÉÇ MüqÉï(lÉÉaÉÉeÉÑïlÉ)
The main property of karma is action.
In Ayurveda, drugs have been classified according to
pharmacological action. If comparative study is done on modes of
classification of drugs in Ayurveda and Allopathic, it can be concluded
that modern drug classification is similar to ancient one.
A. Drugs Acting On Digestive System
Anulomna (Carminative)
Arshoghna
Atisarghna (Antidiarrhoeal)
Kriminghna (Anthelmintic)
Chhardinigrhana (Anti-emetics)
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4. B. Drugs Acting On Respiratory System
Kaphanissaraka (Expectorant):Talishapatra (Taxus baccata)
Kasahara (antitussive) :kantakari(solanum suratens)
Mucolytic expectorant :Vasa(Adhatoda vasica)
Swashara (bronchodialator): Dhatura(Dhatura metal)
C. Drugs Acting On Heart
Hridya (Cardiac tonics):Arjun(Terminalia arjuna)
Shothghna (Anti-inflammatory): Dashamoola
D. Drugs Acting On Circulatory System
Raktaprasadana (Alterative):Sariva(Hemidesmus indicus.) etc.
Raktaskandana (Styptics):Nagakeshar (Messua fera)etc
E. Drugs Acting On Nervous System
Nadi balya (Nervine):Ashwagandha (Withania somnifera) and Kapikachu (Mucuna
prurita),Bhallataka(Semicarpus anacardium) etc.
Nidrajanana (Hypnotics):. Jatamansi (Nardostachys jatamansi) etc.
F. Drugs Acting On Kidney
Ashamrighna (Lithontriptics):. Varuna (Cratevea nurvala) etc
Mutrala (Diuretics):. Gokshura (Tribulus terresteris) and Punarnava
(Boerrhavia diffusa) are diuretics. They are used in treating edema.
Mutrasangheneya:udumbar(ficus glomerata) etc
G: Miscellaneous Drugs_Rasayana, Vajikarana, Yakritautejjaka
(Choleretics) etc
5. :
In this presentation, total 50 dravyas (Drugs) have been
reviewed vividly from all Nighantus (lexicons) and the
karma (clinical pharmacological) based paryaya
(synonyms) only have been assembled .
Around 223 paryayas (synonyms )
Traditional classical claims with evidence based
experiments have been summarized here in order to
correlate & justify its nomenclature
At the end of presentation, dravyas have been categorized
systematically on the basis of their synonyms denoting to
their specific karmas .
Glimpses of Presentation
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7. Chemical Content:
Apioseglycosider,Apiin,Terpineol
T. ammi would increase the secretion of gastric acid; the addition
of T. ammi to the infusion increased the amount of gastric acid.
Gastric acid secretion was increased nearly four-fold by T. ammi.
In experimental rats in vivo, the addition of T. ammi to the diet
reduced food transit time and also enhanced the activity of digestive
enzymes and/or caused a higher secretion of bile acids.[48](Kohli
et all. 1964)
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8. AÌiÉuÉsÉÉ
Latin Name: Abutilon indicum L.
Family Name: Malvaceae
AÌiÉuÉsÉÉ(pÉÉ.mÉë):AiÉÏuÉ uÉsÉSÉlÉ MüUÉåÌiÉÌiÉ
ÌuÉëwrÉÉ (kÉ.ÌlÉ:): It is an effective Aphrodisiac.
uÉ××wrÉaÉÎlkÉMüÉ(UÉ.ÌlÉ):
uÉ×wrÉÉ zÉÑ¢üuÉÍkÉïÌlÉ,aÉÎlkÉMüÉ uÉåaÉeÉlÉÌlÉ,
aÉÎlkÉMüÉ uÉåaÉeÉlÉÌlÉ,uÉ×wrÉÉ cÉÉxÉÉæ aÉÎlkÉMüÉ cÉ. (UÉ.ÌlÉ)
Formulation:
Balaristha,Balataila(mɤrÉÉbÉÉiÉ-AlÉÑuÉÉxÉlÉ-xÉÑ.ÍcÉ.5/19).
Khirabalataila nasya(AÌSïiÉ-xÉÑ.ÍcÉ.5/22)
Charak:
Valya mahakashaya(ch su 4/18)
Vrimhaniya mahakashaya(ch su 4/28)
xÉÉaÉëÉÌWûMü uÉsrÉ uÉÉiÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/40)
Rasayan,vajikaran(ch.chi 1.2.12)
Shukra sruti vridhikar (Dalhan)
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9. Chemical Content
Ephedrin(sympathomimetic) steroids, triterpenoids, alkaloids,
saponins,flavonoids,
A)On Female Libido
Methanolic extract of areal parts of Abutilon indicum was investigated
for the libido enhancement activity at doses 100, 200 and 400 mg/kg
using automated runway methodology and copulatory behavior models.
The results revealed that the extract significantly improved the runway
parameters and copulatory behavior exhibiting its effectiveness in
enhancing the female libido1
B)As Immunomodulatory
In an experimental study the rasayana drugs namely
atibala.bala,mahabala,bhumibala, have been screened for their
immunonenhancing properties,Animals of drug treated group showed
statistically an enhanced properties of Anti S typhi O antibodies,Abutilon
indicumwasbestinaugmentingantibodyproduction.2
1) Effect of Abutilon indicum extract on FemaleLibido in Rats Khadabadi SS1* and Bhajipale NS2Kirtikar
K.R, Basu B.D;
2) IndianMedicinal Plants. Allahabad, India.1956, p. 314-316.
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11. Formulation:
Balachatrubhadra churna
Chemical: Atisenol,Heteratishin
Research
In a clinical trial comprising 30 patients,Ativisha is found to be
effective in Atisara. the ant-diarrheal activity of roots of A. heterophyllum
may be attributed to an antisecretory and anti-enteropooling type effect
as a result of reactivation of Na + and K + ATPase activity mediated
through NO pathway. EAH causes either a decrease in mucosal secretion
or increase in mucosal absorption, which allows the feces to become desic
cated thus retarding its movement through the colon. The above activity
was well supported with a potential antibacterial activity. Thus, the
present study justifies the use of roots of A. heterophyllum in treatment of
diarrhea.
Antisecretory and antimotility activity of Aconitum heterophyllum and its significance in treatment of
. diarrhea
Siva Hemalatha, Divya Jain, Dinesh K Patel, Satyendra K Prasad,Alakh N SahuIndian Journal of Pharmacology,Vol. 46, No. 1,
January-February, 2014, pp. 82-87
मधुनाऽतिविषाश्रृङ्गीविप्िलीलेहयेच्छिशुम ् ।
एकाां िाऽतिविषाां कासज्िरछिर्दिभिरर्दििम ् ।।
(अ.हृ.उ.2.57)
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12. AeÉÑïlÉ
Latin Name: Terminalia arjuna
Family Name:Combretaceae
™SìÉåaÉuÉåËU(Sa)
µxÉlÉåxuÉU(K.N)
AeÉÑïlÉxrÉ iuÉcÉÉ ÍxÉkÉqÉ ¤ÏUqÉ rÉÉåerÉqÉ ¾èSÉqÉrÉå
ÍxÉiÉrÉÉ mÉlcÉqÉÑsrÉÉ uÉÉ oÉsÉrÉÉ qÉkÉÑMåülÉ uÉÉ (ÌuÉë.qÉÉ)
Milk processed withsarkara,panchamula,bala, and madhuka should
be used in cardiac disorders.
cÉÑlÉïqÉ MüMÑüxiÉoÉqÉÏxjÉqÉ uÉxÉ¢üxÉqÉ pÉÌoÉiÉqÉ uÉÉWÒûuÉÉUqÉ
bÉëÏiqÉkÉÑÍxÉiÉÉåmÉsÉqÉ sÉåWûqÉ ¤rÉxuÉÉzÉMüÉxÉÌmÉiÉWûUqÉ
(pÉÉ.mÉë UeÉrZqÉÉ ÍcÉ 12/29)
Powdered Arjun bark impregnated with vasa juice several times should be
taken with ghee honey sugarcandy.it alleviates cough,swasa,pitta etc.
Chemical content
Arjunic acid,Tannins,Arjunolic acid drrout.sibaprasad@gmail.com,24/06/2016
Friday
13. The present study demonstrated prophylactic and
therapeutic potential of Terminalia arjuna bark extract in
isoproterenol (ISO)-induced chronic heart failure (CHF).
Fifteen days after injection of ISO (85 mg/kg twice at an
interval of 24 h, s.c), rats showed fall of left ventricular
pressure, cardiac contractility index (LV (dP/dt)max/LVP),
and rise in cardiac output ,LV end-diastolic pressure. CHF
rats showed a significant increase in serum creatine kinase
isoenzyme-MB (CK-MB) increased level of cytokine tumour
necrosis factor-α (TNF-α) along with histological changes in
heart were also observed in CHF rats. . Cardioprotective
action of T. arjuna was comparable to fluvastatin, a synthetic
drug. The results suggest that T. arjuna bark extract has a
significant prophylactic and therapeutic beneficial effect on
protection of heart against ISO-induced CHF possibly
through maintaining endogenous antioxidant enzyme
activities, inhibiting lipid peroxidation and cytokine levels.
mÉ
Mechanistic Clues in the Cardioprotective Effect of Terminalia Arjuna Bark Extract in Isoproterenol-Induced . . .
. Chronic Heart . . . Failure in Rats
Adila Parveen, Rashmi BabbarSarita AgarwalAnita Kotwani Mohammad Fahim
mÉÉjÉï ¤ iÉå AÌlÉsÉå pÉalÉå U£üxiÉqpÉå oÉsÉåÌWûiÉ(zÉÉå.ÌlÉ)drrout.sibaprasad@gmail.com,24/06/2016
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14. AzÉÉåMü
Latin Name_Saraca ashoka
Family Name-Caesalpinacea
xiÉUÏÌmÉërÉ: used in all gynaecological disorders
AzÉÉåMü:lÉ zÉÉåMüÉxqÉÉiÉ
xqÉUÉÍkÉuÉÉxÉ: xqÉU xqÉëÑÌiÉ iÉzrÉ AÍkÉuÉÉxÉ
Chemical content:
arjunic acid,fredelin,tannin
अशोकवल्कलक्वाथश्रृतं दुग्धं सुशीतल्
यथाबलं पिबेत प्रातस्तीव्रासृग्दरनाशन् . ,
(वृ.्ा.63.5)
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15. Research
Oxytocic activity of the plant was seen in rat and
human isolated uterine preparations. Estrogen-primed or
gravid uterus was more sensitive to the action of the
alcoholic extract. The bark of Saraca ashoka, which is the
real potent drug, is reported to have a stimulating effect
on the endometrium and ovarian tissue tonic contraction
and is therefore very valuable in treating problems like
menorrhagia due to uterine fibroids, in leucorrhea and in
internal bleeding. Ashoka or Saraca indica is helpful in all
cases of uterine bleeding.(B.N GHOSH,PMMT)
(http:// www. da-academy org/dagardenssaraca1.html. )
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16. Anti convulsant activity of methanolic extract of leaf of
Saraca indica Linn shows that it could have blocked the
seizure spread by inhibiting Na+ channels and glutamatergic
excitation through NMDA enhancement of GABA activity
[26]. Hence from the results indicated the presence of
anxiolytic activity inthe Saraca indica Linn. leaf extract by act
through potentiating the GABA inhibition in the CNS as that
of standard drug diazepam.
Neuropharmacological Screening of Saraca Indica leaves
Talever Singh*, Snigdha Gupta, Milind Pande, Mrs Akansha Singh Guru Drone Journal of Pharmacy and
Research. 2014; 2(2): 30 -37
S. Ashoka extracts typically relieve pain by acting on
both the central and peripheral nervous systems
Experimental evaluation of analgesic property of bark skin of Saraca
indica (Ashoka) and Shorea robusta (Shal)
Poonam S. Mohod1, C. R. Jangde2, S. D. Narnaware3, Subhash Raut4
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17. AµÉaÉlkÉÉ
Latin name:Withania somnifera Dunal
Family Name:Solanacea
mÉѧÉSÉ(ÌlÉ.AÉ):mÉѧÉÇ SSÉÌiÉ zÉÑ¢üuÉkÉïlÉÉjÉï
ÇqÉÉÂiÉÎblÉ(xÉÉå)
MüÉqÉÂÌmÉÍhÉ(UÉ.ÌlÉ):
MüÉqÉxrÉ ÂmÉÇ pÉuÉirÉxrÉuÉÉ
It promotes complexion
uÉsrÉÉ(kÉ.ÌllÉ),ÌuÉëwrÉÉ(Måü.ÌlÉ)
Vajikaran(pÉÉ.mÉë)
Shukrala:(zÉÉ)
cÉUMü
Valya,vrihmaniya
Alepan in Rajyakhma
(ch.chi 8/77)
अश्िगन्धाकषायेण कलकक ैः क्षीरां चिुगुिणम ् ।
घृिां िक्िां िु िािघ्नां िृष्यां माांसवििधिनम ् ।। (िृ.मा.22.73)
Vatavyadhi;
Ashwagandha kashaya with four times ghee and milk
pacifies the vata
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18. Rasayan-One who takes the powder of aswagandha root in
late winter mixed with honey & ghee along with milk
regains the youthfulness.
Sedative effect:
In a very high dose, it may have sedative effect.
Hence some experts advice to avoid it during day
िीताऽश्वगन्धा ियसाऽधध्ासं घृतेनं तैलेन सुखाा्बुना वा
कृ शस्य िुपटं विुषो पवधत्ते बालस्य सस्यस्य यथा सुवृपटिः
(अ.हृ.उ.39.158)
Chemical:
Withanol:Aphrodisiac
Enhygriene: Lowering B.P
Somniferin:Sedative Effect
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19. It enhances the function of the brain and nervous system and improves
the memory.
It improves the function of the reproductive system promoting a healthy
sexual and reproductive balance.
Being a powerful adaptogen, it enhances the body’s resilience to stress.
Ashwagandha improves the body’s defense against disease by improving
the cell-mediated
immunity. It also possesses potent antioxidant properties that help
protect against cellular damage caused by free radicals
Withania somnifera treatment prevents, decrease of adrenal cortisol and
ascorbic acid.
Ashwagandha given to a group of mice with milk injection produced
reduction in leucocytosis.
Anabolic effects:
Cognition Promoting Effect
roots of Ashwagandha
significantly reversed ibotenic acid induced cognitive defects in
Alzheimer’s disease model (Bhattacharya et al., 1995)
Anxiolytic effect
Singh et al., Afr J Tradit Complement Altern Med. (2011) 8(S):208-213 208
AN OVERVIEW ON ASHWAGANDHA: A RASAYANA (REJUVENATOR) OF AYURVEDA
Narendra Singh#, Mohit Bhalla, Prashanti de Jager* and Marilena Gilca**
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20. असनैः (बीजकैः)
Latin Name: Pterocarpus marsupium Roxb.
Family name: Fabaceae
MüÉzrÉï: it causes emaciation.
Sesamum oil in the morning with decoction of heartwood . .
of asana mixed with honey effective in sthaulya.
अपतस्थूलशरीरो यपस्तलतैलं mÉëÉगे पिबेत
पिबेदसनसारस्य क्वाथं वा ्धुसंयुत् (वै.्.12.30)
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22. अच्थिसांहारैः
Latin name:Cissus quadrangularis Linn
Family name:Vitaceae
AÎxiÉxÉÇrÉÉåeÉMü:(pÉÉ.mÉë):AÎxiÉÌlÉ pÉalÉxÉÇWûÉUrÉÌiÉ rÉÉåeÉrÉÌiÉ CÌiÉ
Cures fractures, dislocation and causes reunion in fractures.
सघृिेनाच्थिसांहारां लाक्षाां गोधूममजुिनम ् ।
सच्न्धमुक्िेऽच्थििग्ने च विबेि् क्षीरेण मानिैः । (िृ.मा.46.8)
One should take the combination of asthisamhara, lac,wheat
flour,Arjun with milk added with ghee in case of dislocation of joints and
bone fracture.
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23. Research
The anabolic steroids from Cissus quadrangularis
showed marked influence in the rate of fracture healing by
influencing early regeneration of all connective tissues
involved in the healing and quicker mineralization of callus.1
Systemic use of Cissus quadrangularis restores fracture in
four weeks in trial group while the controls required six
weeks. That is due to increase in mucopolysaccharides
level,proliferation of osteoblastic, chondroblastic and cartilage
proliferation, increased mineralization in the callus. Thus the
parenteral administration of the total extract of Cissus
quadrangularis not only neutralized the anti-anabolic effect of
cortisone in healing of fractures but also enhances the
mineralization of the callus possibly due to its vitamin
contents.2
Udupa K.N., and Prasad G., Biochemical and studies on the effect of cissus quadrangularis in fracture repair, lndian J. Med.
Res., 1964, 52, (5) 480-487.Udupa K. N., and Prasad G. C., Further studies on the effect of Cissus quadrangularis in acceleratingGarima Mishra
et al /Int.J. PharmTech Res.2010,2(2) 1308 fracture healing, Indian J. Med. Res., 1964, 52,
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24. आमलकी
Latin Name_Emblica officinalis Gaertn
Family :Euphorbiacea
AqÉëÑiÉÉ(ÌlÉ.AÉ):lÉ ÍqÉërÉiÉå AlÉrÉÉ CÌiÉ
If it is consumed,no untimely death
AÉqÉsÉÌMü(ÌlÉ.AÉ):AÉ xÉqÉÉliÉÉiÉ qÉsÉiÉå kÉÉUrÉÌiÉ
UxÉÉrÉlÉaÉÑhÉÉlÉ CÌiÉ(full of rasayan properties)
uÉrÉxiÉÉ(pÉÉ.mÉë)
ÌuÉëwrÉÉ(pÉÉ.mÉë)
Chemical Content
Hydrolyzable tannins
Emblicanin A,B
Ellagic acid(inhibits the mutation of genes and reduce
chromosomal abnormalities.
AÉqÉsÉMüÐ uÉrÉxiÉÉmÉlÉÉÇ(cÉ.xÉÑ25/40)
ÌlÉirÉ xÉåuÉÌlÉrÉ SìurÉ(cÉ.xÉÑ 5/12)
AÉqÉsÉMüÐ cÉÑhÉï:uÉwÉïzÉiÉqÉ AeÉUÇ(cÉ.ÍcÉ1/1/8)
U£üÌmÉ¨É mÉëqÉåWûblÉ mÉUÇ ÌuÉëwrÉ UxÉÉrÉlÉ (pÉÉ.mÉë)
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25. Research
The fruits extracts of Emblica officinalis (Amla) has
been reported to have strong anti-oxidant properties..
Chromium (Cr), an immunosuppressive agent results in
enhanced cytotoxicity, free radical production, lipid
peroxidation and decreased glutathione peroxidase (GPx)
activity and diminished glutathione (GSH) levels. There was a
significant inhibition concanavalin-A-stimulated lymphocyte
proliferation. Chromium also inhibited Con A .Amla
significantly inhibited Cr-induced free radical production and
restored the anti-oxidant status back to control level. Amla
also inhibited apoptosis and DNA fragmentation induced by Cr.
Interestingly, Amla relieved the immunosuppressive effects of
Cr on lymphocyte proliferation and even restored the IL-2 and
γ-IFN production considerably.
Ram, M. Sai, et al. "Cyto-protective and immunomodulating properties of Amla (Emblica officinalis) on lymphocytes: an
. in-vitro study." Journal of Ethnopharmacology 81.1 (2002): 5-10.
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26. आरग्िधैः
L.N: Cassia fistula Linn
Family:Leguminoseae
AÉUauÉkÉ(ÌlÉ.AÉ);AÉUaÇ UÉåaÉxÉÇMüÉqÉÌmÉ WûÎliÉ
it eliminates the diseases with mere doubt
AÉUuÉåiÉ- AÉ UåuÉrÉÌiÉ ÌlÉÈxÉÉUrÉÌiÉ qÉsÉqÉ xÉÉUYiuÉÉiÉ.
It acts as laxative.
MÑü¸xÉÑSèlÉ(Ra.Ni), euÉUÉliÉMü(sodhal)
AÉqÉWûÉ(shodhal), urÉÉÍkÉbÉÉiÉ(K.N)
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27. आरग्िधे िा ियसा मृद्िीकानाां रसेन िा।
त्रििृिाां िायमाणाां िा ियसा ज्िररिैः विबेि् ।।
(च.चच. 3.232)
Aragwadha with milk and grape juice alleviates jwar.
आरग्िधथय ििाणण आरनालेन िेषयेि् ।
दद्रुककर्ििकु ष्ठातन हच्न्ि भसध्मानमेि च ।।
(बां.से.कु ष्ठ.63)
Leaves of aragwadha pounded with sour gruel and applied
on the part of ring worm,kitibha,kustha,sidhma .
आरग्िधथय ििाणण िृष्िातन किुिकलिैः ।
आमघ्नातन नरैः कु यािि ् सायां िक्िािृिातन च ।।
(िा.प्र.चच.26.52)
Leaves of aragvadha fried with mustard oil and taken in
evening followed by meal.It alleviates ama.
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28. Research The plant contains more or less same
components such as saponin,
triterpenoids, steroids, glycosides,
anthraquinone, flavonoids, gum,
mucilage, proteins and aminoacids.
From the above results, the activity of
hydroalcoholic extracts of C. fistula
shows significant antibacterial and
antifungal activity. The chloroform
extracts, whose purity level is good as
compared to hydroalcoholic extract
and porosity is lower than
hydroalcoholic extract, found to be
more active against fungal strains.
Results shows that this plant is rich in
tannin and phenolic compounds have
been shown to possess antimicrobial
activities against a number of
microorganisms.
In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts
N. R. Bhalodia, P. B. Nariya,1 R. N.Acharya,2 andV. J. Shukla3
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29. इङ्गदी
Latin name:Balanites aegyptica L.Delie
Family:Simarubaceae
ChaÉÑÌS(Ni.Adrsha):
CaÉqÉ MÑü¸pÉÑiÉaÉëWûÉÌSlÉÉzlÉqÉ
It removes the dosas and cures conditions like kustha
ÌuÉwÉÎblÉ(sodhal):Antipoisonous
MüÉzrÉmÉ-ÍzÉzrÉÉåmÉlÉrÉlÉ xÉÇxMüÉU
xÉÑ´ÉÑiÉ-UÉåqÉxÉÉiÉlÉ(xÉÑ.ÍcÉ1/108)
cÉUMü-mÉëxÉÑiÉÉaÉëÑëWû(cÉ.zÉÉ8/34)
कु ष्ठेषु हितान्यािुChaÉÑÌSस्तैलम् (च.हच.7.119)
मूवषकविषे
भशरीषेङ्गदकलकन्िु भलह्यात्ति समाक्षक्षकम ् । (सु.क.7.12)
Ingudi fruit kalka with shirish and honey useful in Rat
poisoning. drrout.sibaprasad@gmail.com,24/06/2016
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30. Research
Alcoholic extracts fruit of B. aegyptiaca have remarkable
antimicrobial potential and thus can be used to derive
antimicrobial agents especially against S. aureus, E. coli,S.
typhi and S. paratyphi A. Hence, it can be used in the
treatment of enteric fever, diarrhea, wound infections and
urinary tract infections.
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Friday
31. इन्द्रिारुणी
Latin name:Citrullus colocynthesis Linn
Family name: Cucurbitaceae
ClSìèuÉÉÂÍhÉ:ClSìÉ zÉÌ£üxÉqmÉlÉÉï uÉÉÂÍhÉ eÉsÉUåcÉÌlÉ.
ÌuÉzÉÉsÉÉ(ÌlÉ.AÉ):
ÌuÉzÉåwÉåhÉ zsÉÌiÉ- cÉsÉÌiÉ MüÉqÉsÉÉÌSUÉåaÉiÉÌlÉuÉUÉÌrÉiÉÑ
It spreads all over body to cure the conditions like jaundice
etc.
ÌuÉwÉÎblÉ:(xÉÉå):ÌuÉwÉqÉ WûÎliÉ
र्हिा गिाक्षी सगुडा च शुण्ठी (सु.उ.44.30)
Indravaruni mixed with jaggery & shunthi useful in kamala.
ccc
cÉUMü
qÉÑÍsÉÌlÉ(xÉÑ/1/77,ÌuÉUåcÉlÉ(xÉÑ/2/9)
xÉÑ´ÉÑiÉ
AkÉÉåuÉÉaÉWûU(xÉÑ.xÉÑ.39/4)
Colocynthin acts as
gastrointenstinal
irritant,produces abdominal
pain,watery stool
drrout.sibaprasad@gmail.com,24/06/2016
Friday
32. ESÒqoÉU
Latin Name: Ficus glomerata Roxb.
Family Name:Moracea
ESÒqoÉU(pÉÉ.mÉë):
ESÒqoÉsÉ mÉë¢Ñü¹oÉsÉMüU CirÉijÉï
The ripe fruit eaten promotes strength to body.
qÉsÉrÉÑ:(ÌlÉ.AÉ): qÉsÉqÉ ÍµÉ§ÉqÉ ÌlÉWûÎliÉ.(It cures leucoderma.).
(Kakudumbar:ficus hispida)
1st Brahmarasayan
Patra-udumbar
(ch.chi1/1/57)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
33. एरण्डैः
Latin Name:Ricinus communis Linn
Family:Euphorbiacea
LUhQû:(pÉÉ.mÉë): LUrÉÌiÉ uÉÉrÉÑqÉ CÌiÉ
uÉÉiÉÉËU (R.N);uÉÉiÉxrÉ AËU zɧÉÑ lÉÉzÉMüÉå CÌiÉï
zÉÑsÉzɧÉÑ:(Sa.Ni)
cÉUMü:uÉëÑwrÉuÉÉiÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/0)
xÉÑ´ÉÑiÉ:AkÉÉåuÉÉaÉWûU(xÉÑ.xÉÑ.39/4)
U.U.xÉ/pÉÉ.mÉë:AÉqÉuÉÉiÉ
P.V Sharma_vedanasthapan LUhQû zÉÉåTüzÉÑsÉblÉ ÌuÉëwrÉ uÉÉiÉWûUÇ mÉUÇ(UÉ.ÌlÉ)
The mechanism of analgesic effect of ricinolic acid could probably be
due to inhibition of the effect of endogenous substances
that induces pain at nerve endings similar to that of NSAIDs.
r,
1,*
ÌuÉश्व्ेरण्डजं ्ूलं क्वाथपयत्वा जलं पिबेत
प ंगुसौवर्धलोिेतं सद्यिः शूलपनवारण् (भा.प्र.पर्.30.57)
One should take decoction of shunthi,root of errand,
hingu & rock salt, gets instant colic relief
drrout.sibaprasad@gmail.com,24/06/2016
Friday
34. Research
Central analgesic activity:
The crude extract of root bark of R. communis possesses central
analgesic activity in tail flick response model to radiant heat at a dose of
250mg/kg. The ethanolic extract of pericarp of root bark of R. communis
possesses typical CNS stimulant and neuroleptic effects. The stimulant
effects, such a exophthamus, hyperreactivity (evidenced by tremors or by
the pinna and grip-strength reaction), memory improvement and clonic
seizures, seem to be due to the presence of the alkaloid ricinine. On the other
hand,compounds other than ricinine may be responsible for the neuroleptic-
like effects of the extract,because ricinine did not cause reduction of
locomotor activity or catalepsy in the mice.
Ferraz A.C., Angelucci M.E.M., Da Costa M.L., Batista I. R., De Oliveira B.H. and Da Cunha C. Pharmacological Evaluation of
Ricinine, a Central Nervous System Stimulant Isolated from Ricinus communis. Pharmacology Biochemistry and Behavior1999; Vol.
63: No. 3: 367–375.
drrout.sibaprasad@gmail.com,24/06/2016
Friday
35. MüOÒûMüÉ
L.N: Pichrohiza Kurroa Royle ex. Benth
F.N- SCROPHULARACEAE
MüOÒûMüÉ(pÉÉ.) MüOûÌiÉ UÉåaÉqÉ ÌuÉëhÉÉÌiÉ CÌiÉ
It engulfs the diseases.
AËU¹(kÉ.ÌlÉ):lÉ ËU¹qÉÉzÉÑpÉxrÉ
AÉqÉÎblÉ(kÉ.ÌlÉ) it pacifies the ama.
अम्लवित्ते
किुकाभसिा ऽिलेह्या ििोलविश्िां च क्षौद्रसांयुक्िम ्(िृ.मा.53.14)
ÌlÉrÉÌiÉ MüÉÍsÉMü euÉU-pÉÉ.ÌlÉ
वित्तज्िरघ्नी किुका श्र्लेक्ष्णविष्िा सशकि रा । (अ.सां.चच. 1.76)
cÉ
cÉUMü:sÉåZÉÌlÉrÉ,pÉåSÌlÉrÉ
xÉÑ´ÉÑiÉ:qÉÑxiÉÉÌS,mÉOûÉåsÉÉÌS-AÉqÉÌiÉxÉÉUlÉÉzÉlÉqÉ
ÌuÉzÉåwÉÉiÉ SÉåwÉmÉÉcÉlÉ
ÌmÉë.zÉ-ÌmɨÉÌuÉUåcÉMü
M.C of Arogyvardhini
Total use-28 diseases(B.R)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
36. Research
Iridoid glycosides like kutkin, Picroliv, Picrisides I, II, III&IV,Kutkosides
are the chemical moieties that may be responsible for
Antipyreticactivity.
Ghisalberti E.L, Biological and Pharmacological activity of naturallyoccurring Iridoids and Secoiridoids,Phytomedicine 5, 147-163, 1998.drrout.sibaprasad@gmail.com,24/06/2016
Friday
37. MühOèMüÉËU
Latin name-Solannum surattens Burm f
Family:Solanacea
MüÉxÉÎblÉ(pÉÉ.)
SìÉuÉÍhÉ:(A.ÌlÉ) zsÉåwqÉÉhÉÉqÉ SìÉuÉrÉÌiÉ
(MüTü ÌlÉxÉÑSlÉqÉ xÉÑ.xÉÑ,38)
urÉÉÍbÉ((pÉÉ.)ë:urÉÉÎeÉbÉëÌiÉ aÉlkaÉëWûhÉqÉ MüUÉåÌiÉ
It improves olfactory function
(Bapal Vaidya)
ÌlÉÌSÎakÉMüÉ(ÌlÉ.AÉ)-ÌlÉiÉUÉqÉ ÌS½iÉåxqÉ,EwlÉiuÉÉÌS aÉÑhÉå CÌiÉ
Owing to its ushna tikshna ,it spreads
all ovder body easily,alleviates diseases.
Major chemical constitutes:
BCarotene,Disgenin,
Solanocarpine(Solanine-S), Tomatidienol etc.
Charaka
Kasahara Hikkanigrahana
Kanthya
A.H:MüÉxÉåÌlÉÌSÎakÉMüÉ(A.¾û.E )
ÌmÉë.ÌlÉ-MüÉxÉWûU
िीनसे ;व्याघ्रीतैल् (शा.सं.2.9.180)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
38. Gautam et al. 2008 studied effects of Solanum xanthocarpum extract on some of
the parameters like smooth muscle relaxation, and antagonism of asthma mediators
such as histamine, eiosinophils and protection against mast cell degranulation which
seemed to be prominent in pathophysiology of asthma. Further they showed that
ethanol extract of Solanum xanthocarpum shown a significant antihistaminic activity
in histamine induced contractionin goat tracheal chain preparation.Thus, the
significant inhibition of histamine induced contractions produced by ethanol extract
of Solanum xanthocarpum flower on isolated goat tracheal chain preparation indicates
that the Solanum xanthocarpum flower has antihistaminic (H1- receptor antagonist)
action.While screening the all three extracts of flowers of Solanum xanthocarpum,
results were indicative that only ethanolic extract of Solanum xanthocarpum at a dose
of 50 and 100 mg / kg reduced milkinduced eiosinophilia of statistical significance.
Solanum xanthocarpum at a dose of (50- 100 mg/kg, i.p) showed significant mast cell
stabilization as compared to standard drug
Disodiumchromoglycate (DSCG).
Vadnere GP, Gaud RS, Singhai AK; Evaluation of Anti-Asthmatic Property of Solanum Xanthocarpum Flower Extracts. Pharmacology
online, 2008; 1: 513-522.
कण्टकारीरसे पसद्धो ्ुद्गयूषिः सुसंस्कृ तिः
सगौरा्लकिः सा्लिः सवधकासपभषपग्जत् (र्.पर्. 18.184)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
39. MüÌmÉMücNÒûBotanical name: Mucuna pruriens Hook.
Family: Fabaceae
MühQÒûUÉ(pÉÉ.)
ÌuÉëwÍpÉ((pÉÉ.)
ÌuÉëzrÉÌuÉeÉÉ(kÉ.ÌlÉ)
Charak;Valya mahakashya(ch.su 4/7)
Vrihmani gutika,apatyakar swaras-vajikara(ch.chi)
Amritprasghreet,2nd sarpiguda-kshatkhina(ch.chi 11
Sarangdhar:Vajikar dravya
Mucuna Pruriens L Dopa crosses BBB,decarboxylated
& converted into Dopamine.
L-Dopa
DOPAMINE INHIBITS PROLACTIN AND PRESERVES TESTOSTERONE
Deficiency of L
Methyl Dopa causes
Parkinsonism.
Kapikachu D.O.C IN
Parkinsonism
% of L-DOPA at
Velvet Bean
Outer Pericarp:3-6%
Endocarp:5.3%
ADR
GastricUpset,Breathlessn
es,Insomnia,Headache,
Local irritation
drrout.sibaprasad@gmail.com,24/06/2016
Friday
40. Methanolic extract of Mucuna pruriens seed was
tested for their possible androgenic activity in
Wistermale albino rats. The methanolic extract of
M. pruriens plant was gavaged separately into 2
group of ratat similar doses of 1000 mg/kg b.wt and
1500 mg/kg b.wt for 30 days. At the end of the
treatment, the animals were killed and the blood,
testis, epididymis, seminal vesicles and prostate
were collected for biochemical analysis. The
methanolic extracts of M. pruriens significantly
increased the relative weight of the testis, serum
and testicular testosterone level, protein level in
the testis and epididymis, and epididymal alkaline
phosphatase activity. The methanolic extracts of
M.pruriens possess androgenic activity.
Evaluation of androgenic activity of Mucuna pruriens in male rats
K. Muthu1* and P. Krishnamoorthy2
वानरी वपटका (भा.प्र.पर्.72.71-75)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
42. Ethanolic extract of Mallotus philippinensis fruit
(200 mg/kg) was administered orally, once daily for
10 days .MPE was found safe when given to rats upto
10 times of optimal effective dose. Mallotus
philippinensis has been tested in-vitro for wound
healing activity by examining the proliferation,
migration of mesenchymal stem cell by secreting
various cytokines to wounded site from bone
marrow to systemic circulation and finally remodel
wounded tissues
Mallotus philippinensis Muell. Arg fruit glandular hairs extract promotes wound healing on different wound model in rats
BMC Complementary and Alternative Medicine Sampledoi:10.1186/s12
drrout.sibaprasad@gmail.com,24/06/2016
Friday
43. MÑÇüMÑüqÉ
L.N:Crocus Sativus Linn
F.N:Iridaceae
MÑÇüMÑüqÉ:MÑüYrÉiÉå AÉÌSrÉiÉå ÍzÉUÉåÂaÉ uÉëhÉÌSlÉÉzÉlÉjÉï
It is used in headache,wound etc.(ni.adarsh)
uÉhrÉïqÉ(pÉÉ.mÉë)
Excess intake of saffron at
pregnancy might cause
contraction of uterus leading to
possible miscarriage.
Headache,Anxiety,Skin
allergies,Dryness of mouth
Stomach upset if saffron taken
more.
शकध राकु ङक्श्रृतं घृतं पित्तासृगन्वये (अ.हृ.उ.24.7)
Headache caused due to pitta=rakta to be aleeviated with
intake of snuff of ghee cooked with sarkara and kumkuma
drrout.sibaprasad@gmail.com,24/06/2016
Friday
44. MÑüOûeÉ
zÉ¢ü:zÉYlÉÉåÌiÉ CÌiÉ AÌiÉxÉUÉÌS UÉåaÉÉlÉ
(ÌlÉ.AÉ)
xÉlaÉëÉÌWû:mÉÑËUwÉqÉ xÉlaÉëÉëWûÌiÉ
mÉÑÇMÑüOûeÉ Îx§ÉMÑüOûeÉ
(H.antidysenterica) (Wrightia tomentosa)
ÌuÉëWûiÉ TüsÉ zrÉÉqÉ
µÉåiÉmÉÑwmÉ TüsÉÌuÉëliÉ AhÉÑ
ÎxlÉakÉmÉ§É AÂhÉmÉÑwmÉ
ÌiÉ£ü UxÉ qÉkÉÑU
Acharya Dalhan strictly opines that pum kutaj to be used in the
management of Atisara(Diarrhoea)
Charak
Arshoghna,Kandughna
MÑüOûeÉiuÉMü
zsÉåwqÉÌmÉiÉU£üxÉÉÇaÉëÉÌWûMüÉåmÉzÉÉåwÉÉhÉÉqÉ
(cÉ.xÉÑ25/40)
Isolated use of Kurchicine as antidiarrhoel is not safe as Kutajghanvati in atisaradrrout.sibaprasad@gmail.com,24/06/2016
Friday
45. H. antidysenterica produces gastrointestinal tract
stimulation by activation of histamine receptors and
relaxes the gastrointestinal tract by Ca++ channel
blockade, which provided the basic ground for its
usefulness in gut motility problems such as
constipation, colic and diarrhea [8]. The alkaloid
conessin posseses Ach inhibitory activity and act as
antidiarrhoeal.
The present study concludes that ethanolic extract
of H. antidysenterica seeds is effective against
noninfectious as well as infectious diarrhea as it
possesses antimicrobial and antidiarrheal property.
Evaluation of antidiarrheal activity of ethanolic extract of Holarrhena antidysenterica seeds in rats
Dushyant Kumar Sharma, Vinod Kumar Gupta, Surendra Kumar, Vet World. 2015 Dec; 8(12): 1392–1395drrout.sibaprasad@gmail.com,24/06/2016
Friday
47. Research:
The ethanolic extract of seeds of A. longifolia was
administered to groups of rats in 100, 150 and 200 mg
kg⁻¹ doses for a period of 28 days, and the action
compared with control rats. The ethanolic extract
exhibited pronounced anabolic effects in treated animals,
as evidenced by gains in the body and reproductive organ
weights. Increased spermatogenesis due to treatment with
extracts was also witnessed in transverse section. The
treatment further markedly affected sexual behaviour of
the animals, as reflected by the reduction of ML, increase
in MF and enhanced attractability towards females. A
significant increase in the sperm count as well as fructose
levels of seminal vesicles was noted.
Effect of Asteracantha longifolia seeds on the sexual behaviour of male rats.
Chauhan NS1, Sharma V, Dixit VKNat Prod Res. 2011 Sep;25(15):1423-31. doi: 10.1080/14786410802588493. Epub 2011
Jul 8.
drrout.sibaprasad@gmail.com,24/06/2016
Friday
48. ZÉÌSU
L.N:Acacia catechu
F.N:Mimosaceae
MÑüwPèblÉ(pÉÉ.)
aÉsÉUÉåaÉÌlÉëiÉ(xÉÉå)
SliÉkÉÉuÉlÉ(pÉÉ)
qÉåSÉåblÉ(xÉÉå)
uÉëhzÉÉåkÉlÉ(UÉ.ÌlÉ)
व्रणशोधने(cÉ.ÍcÉ.25/84)
त्रिफला खर्दरो दािी न्यग्रोधार्दबिला कु शैः। (च.चच.199-206)
तनम्बकोलकििाणण कषायाैः शोधनाैः मिाैः । मुखरोगे;खदिरादिगुडिका,
Heartwood is used to yield concentrated aqueous extract i.e. Cutch
and Katha. The cutch and Katha (extract) possess astringent, cooling
and digestive properties; and is commonly used in throat, ulcers by
reducing inflammation etc
The Pharma Research (T. Ph. Res.), (2011), 5(2); 273-293 ACACIA CATECHU WILLD–A GIFT FROM AYURVEDA TO MANKIND” –
A REVIEWLakshmi.T , Anitha Roy
Use of Acacia catechu C.I in breast feeding.
Side Effect:Hypotension
खर्दरथय ििा क्िािो यिाlÉÏक्िाि एि च
क्िािश्र्च तनम्बमूलथय दन्िरोगतनिारणैः
।। (हा.सां.3.46.14)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
49. Research
Significant reduction of blood glucose level was observed in non
diabetic albino rats following single dose treatment with the test drug at a
dose of 500 mg/kg, p.o. ( P <0.01). Significant reduction of blood glucose
level was also evident in diabetic rats at doses of 250 and 500 mg/kg
( P <0.001). In the present study, preliminary phytochemical screening
of Acacia catechu found the presence of flavonoids and reports
substantiate the presence of
catechutanicacid, quercetin,catechin,pseudotannin,phlabotannin,polypheno
ls, epicatechin and cyanidanol compounds in A. catechu . The antimicrobial
and hypoglycaemic properties of Acacia catechu may be described to the
presence of flavonoids, It is thought that catechu may contain chemicals
that can decrease inflammation and kill bacteria.
which have been shown to inhibit cyclooxygenases and promote β-cell
regeneration besides having insulin secretagogues and antioxidant
properties.
Antipyretic, antidiarrhoeal, hypoglycaemic and hepatoprotective activities of ethyl acetate extract of Acacia catechu Willd. in albino
rats
D Ray1, Kh. Sharatchandra2, IS Thokchom3
drrout.sibaprasad@gmail.com,24/06/2016
Friday
50. Active constituent
Tannins
Acts topically as astringent to mucosal surfaces and following oral
ingestion it consequently get hydrolyzed and alter the fluidity of the
bowel contents (so used in anti-diarrheal remedies) .They are also
attributed with anti-hemorrhagic, anti-inflammatory and antacid
properties. Catechin Have significant antioxidant and antimicrobial
effects. It is considered to be the best antioxidant
Flavonoids
Increase secretion of insulin and inhibit cycloxygenase and
lipoxygenase .Thus it possesses anti diabetic and anti-inflammatory
effect.
Taxifolin Potent Antibacterial agent.
Noreen et. al; Planta Medica 64, 1998; United States. 29.Hocking D. 1993. Trees for Drylands. Oxford & IBH
Publishing Co. New Delhi. drrout.sibaprasad@gmail.com,24/06/2016
Friday
52. Research
Several possible mechanisms have been proposed for hypolipidemic
activity of guggulsterone. cholesterol 7α-hydroxylase (CYP7A1) the rate-
limiting enzyme in the classic pathway of bile acid synthesis from
cholesterol in the liver (he expression of CYP7A1 is negatively regulated
by bile acids through a negative feedback circuit involving Conversion of
cholesterol to bile acids and subsequent excretion through the
enterohepatic circulation represent a major pathway to remove excessive
cholesterol from the body (Russell 2003). The is several nuclear receptors
including bile acid sensor FXR, liver receptor homolog 1 (LRH-1),
Recent studies have established that guggulsterone is an FXR antagonist
has been suggested as a mechanism for the cholesterol-lowering effect of
guggulsterone
Bile acid sensor(FXR)-Liver receptor homolog(LRH1)-Small
heterodiametre partner-cholesterol 7 alpha hydroxylase
Russell 2003; Fuchs 2003). T(Urizar et al. 2002; Wu et al. 2002) (Urizar et al. 2002)
(Lu et al. 2000; Goodwin et al. 2000; Davis et al. 2002) drrout.sibaprasad@gmail.com,24/06/2016
Friday
53. aÉÑQÒûÍcÉ
aÉÑQÒûÍcÉ(Bh.P): aÉÑQûÌiÉ UZrÉÌiÉ CÌiÉ aÉÑQû UZÉhÉå
It protects the body against various diseases.
euÉUlÉÉÍzÉÌlÉ(xÉÉå)
UxÉÉrÉÌlÉ(pÉÉ)
uÉrÉxjÉÉ(pÉÉ)
ÌuÉwÉÎblÉ(pÉÉ)
aÉÑQÒûÍcÉ euÉU pÉÑiÉÎblÉ uÉÍsÉmÉÍsÉiÉlÉÍzÉÌlÉ(zÉÉå)
uÉrÉxiÉÉmÉlÉ,SÉWûmÉëzÉqÉlÉ(cÉ.xÉÑ4)
xÉuÉïeuÉUWûU(pÉÉ.mÉë)
AqÉëÑiÉÉxuÉUxÉ-ÎeÉhÉïeuÉUWûU(zÉÉ)
euÉU SÉWû lÉÉzÉlÉ(rÉÉå.U)
पवष्ज्वरे:पिफलायािः कषायं वा गुडूच्या रस्ेव वा (र्.पर्.3.299)
रसायने (र्.पर्.1/3/31)
मण्डूकण्यायाः स्वरसाः प्रयोज्याः क्षीरेण यष्टीमकुकस्य चूणयम्
रसो गुडूच्यास्तु समूलपुष्पयााः कल्काः प्रयोज्याः खलु शंखपुष्पयााः
L.N:Tinospora cordifolia,(Willd)
F.N: Menispermaceae
,
xÉÑ´ÉÑiÉ:
uÉåÎssÉiÉMü xÉÏuÉlÉ(xÉÑ.xÉÑ.25/21)
drrout.sibaprasad@gmail.com,24/06/2016
Friday
54. Research
Enhanced lysozyme production was reported at different time intervals
Ethanolic extract of stem and leaves of T.Cordifolia
exhibits the significant antipyeretic activity(vedavathy
,rao)
Int J Ayurveda Res. 201
0
Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) – validation of the Ayurvedic pharmacology through
experimental and clinical studiesAvnish K. Upadhyay, Kaushal Kumar,1 Arvind Kumar,2 and Hari S. MishraAudrrout.sibaprasad@gmail.com,24/06/2016
Friday
55. aÉÉåZÉÑU
L.N:Tribullus terestriss(Zygophallaceae)
mÉsÉlMüwÉÉ(pÉÉ):mÉsÉÇ qÉÉÇxÉÇ ÌWûlÉÉÎxiÉ AÌiÉ MÇüOûÌMüiuÉÉiÉ
cÉUMü
qÉѧÉÌuÉUåcÉÌlÉrÉ,zÉÉåjÉWûU
qÉѧɢÑüdlÉ
AÌlÉsÉWûUÉhÉÉqÉ(cÉ.xÉÑ.25/40)
Yatra Akrutihi, tatra gunaaha
vasanti.
Tribulus fruits have quite
resemblance with oxalate stones of
kidney and bladder
Oxalate stone structure T. Fruit
Interesting Fact
drrout.sibaprasad@gmail.com,24/06/2016
Friday
56. Research
Anti-cholestrolemic effect: Saponin fraction
of dried root, administered by gastric intubation
to rabbits decreased the development of protein,
carbohydrate, lipid dystrophy of the liver vs
cholesterol loaded animals. [12]
Hypoglycemic and hypolipidemic
effects: The extract of both T alatus and T
terrestris significantly decreased the blood glucose
levelsin diabetic rats. [29]
drrout.sibaprasad@gmail.com,24/06/2016
Friday
57. cÉ¢üqÉSï
L.N:Cassia tora f.n: Caesalpinacea
MÑü¸WûÉ(pÉÉ.mÉë)
SSìÓblÉ(pÉÉ.mÉë)
mÉÉmÉbÉÉÌiÉ(xÉÉ
Kharjughna(Dh.Ni)
चक्रमदिकबीजातन जीरकां च समाांशकम ् ।
थिोकां सुदशिनामूलां दद्रुकु ष्ठविनाशनम ् ।। (बां.से.कु ष्ठ.67)
Seed paste with jeerak and sarkara in equal quantity is applied
externally in eczema,leprosy, tinea, allergic
dermatitis, psoriasis, å)
Eng.Name: Ring worm plant
Dadrukanduhara, Kantikara:Dh.Ni
drrout.sibaprasad@gmail.com,24/06/2016
Friday
58. Research
The major antifungal compound was identified as
chrysophanic acid-9-anthrone, the structure of
which was assigned on the basis of its chemical
properties and uv, ir, nmr and mass spectral
analysis. The compound was active against
Trichophyton rubrum, T. mentagrophytes,
Microsporum canis, M. gypseum and Geotrichum
candidum.Opportunistic diseaseas.
Isolation of chrysophanic acid-9-anthrone, the major antifungal principle of Cassia tora.
Acharya TK, Chatterjee IB drrout.sibaprasad@gmail.com,24/06/2016
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63. Anti-inflammatory activity-
An experimental study was carried out(Rajashekar M et al;
2006) to evaluate the effect of oral administration of root
powder of O. turpethum and its polyherbal formulation
Avipattikar churna on rat paw edema in albino rats. Results
indicated that pretreatment with the root powder of O.
turpethum and Avipattikara churna (100 mg/kg body
weight)reduced the formalin induced edema volume tothe
extent of 36.45% and 27.11%respectively.
Rajashekar M. Bhande, Laakshmayya,Pramod Kumar, Nitin K. Mahurkar, & S.Ramachandra Setty, Pharmacological
Screening of Root of OperculinaTurpethum and its Formulations. Acta Pharmaceutica Sciencia, 48: 11-17, (2006).drrout.sibaprasad@gmail.com,24/06/2016
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64. SÉÂWûËUSìÉ
Botanical name – Berberis aristata Dc.,
Family – Berberidaceae
Ì¢üÍqÉWûUÉ(xÉÉå)
mÉÇcÉmÉÇcÉÉ(pÉÉ):
mÉÉMüÉlÉliÉUÇ mÉcÉÌiÉ kÉÉiÉÑmÉÉMÇü MüUÉåÌiÉ rÉ¢ÑüiÉ E¨ÉåeÉMü
MüUÉåÌiÉ cÉ
ÌuÉzÉÉåÍkÉlÉÏ(Måü.ÌlÉ)
SÉuÉÏïï iuÉcÉÇ MüsMåülÉ mÉëkÉÉlÉÇ uÉëhÉUÉåmÉhÉqÉ (cÉ¢üS¨É)
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व्रणे
दुवाधस्वरसपसद्धं वा तैलं कप्िल्लके न वा
दावीत्वर्श्च कल्के न प्रधानं व्रणरोिण् (र्.पर्.25.93)
65. Research
The main constituents of root were identified as
berberine, berbamine and palmatine through HPTLC.
The extract besides being safe, lowered the blood
glucose significantly without any hypoglycemic effect on
their control counterparts. It increased CAT, SOD,
GPx, GR activity significantly and reduced lipid
peroxidation (41.6%) and protein carbonylation
(30.15%). It also increased the glucokinase and glucose-
6-phosphate dehydrogenase activities Thus, the extract
of Berberis sristata (root) has strong potential to
regulate glucose homeostasis through decreased
gluconeogenesis and oxidative stress.
Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in
diabetic rats
Jyotsna Singh, Poonam Kakkar
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66. The aqueous root extract of Berberis aristata
showed good hepato protective activity when
administered at doses of 10mg/kg and 20 mg/kg; i/p
and the effects were dose dependent. Serum ALT,
AST, ALP activities significantly decreased in a dose-
dependent manner The present study demonstrates
that berberine possesses hepatoprotective effects
against CCl4-induced hepatotoxicity and that the
effects are both preventive and curative.
HEPATOPROTECTIVE ACTIVITY OF BERBERISARISTATA ROOT EXTRACT AGAINST CHEMICAL INDUCED ACUTE
HEPATOTOXICITY IN RATS
Navdeep Dehar, Rani Walia, R.BVerma, Pinky Pandeydrrout.sibaprasad@gmail.com,24/06/2016
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67. SìɤrÉÉ
L. n – Vitis vinifera Linn
Family-Vitaceae
uÉëÑÇWûÍhÉ(Mãü.ÌlÉ)
rɤqÉÎblÉ(zÉÉå.ÌlÉ)
´ÉqÉÉmÉWûÉ(pÉÉ.mÉë)
Resveratrol present in grapes is a very
potent anti – oxidant. Grapes are rich
sources of vitamin E (anti-oxidant vitamin)
MüÉxÉWûU,euÉUWûU,´ÉqÉWûU qÉWûMüwÉÉrÉ(cÉ.xÉÑ4),
xÉÇiÉmÉïÍhÉrÉ (cÉ.xÉÑ 23/38)
TüsÉÉå¨ÉqÉÉ(cÉ.xÉÑ 25/39)
uÉëÑWÇûÍhÉ ÌuÉëwrÉÉ(cÉ.xÉÑ 27/125)
द्राक्षाबिल्वशिवािीनाां फलां िुष्कां गुणाचिकम् ||५१||
– Bhavaprakasha
grapes with milk is best avoided
(samjog virudha)(ch su 26/19)
Gostani variety draksha best
Draksha help to strengthen lungs.
Expectoration of kapha or
Phlegm achieved with the help of
this fruit. Thus grapes main
ingredients ayurvedic
respiratory conditions like
Tuberculosis, cough, bronchitis
क्षयरोगे(सु.उ.41.40)
द्राक्षापसता्ागपधकावले िः सक्षौद्रतैलिः क्षयरोगघाती
drrout.sibaprasad@gmail.com,24/06/2016
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68. ÌlÉqoÉ
L.N: Azadirachta indica A.Juss
F.N: Meliaceae
AËU¹(pÉÉ.)lÉ ËU¹qÉzÉÑpÉqÉxqÉÉiÉ,xÉuÉïUÉåaÉlÉÉzÉMü
¢ÑüÍqÉblÉ(Mãü.ÌlÉ)
NûSïlÉ(Mãü.ÌlÉ)
ÌmÉcÉÑqÉSï(pÉÉ.mÉë):
ÌmÉcÉÑqÉ MÑü¸qÉ qÉSïrÉÌiÉ lÉÉzÉrÉÌiÉ
mÉÑrÉÉËU(zÉ.)
Charaka Samhita
Kandughna(ch.su4)
Tiktaskandha(ch.vi 8/143)
Kusthanashak kasaya
(ch.chi 7/92)
Jantudagdha,Lashikaprasut
kustha:Nimba-vidang pana &
lepa with gomutra(ch.chi 8/157)
Neem seed oil and leaf extract is
spermicidal,
inhibits spermatogenesis,
antiimplantation,abortificient properties
wchich enables to prepare contraceptive
from neem oil(Sinha Et all.1984)
YONI DHUPANWITH
NIMBA KASTHA BEFORE
VYAVAYA
CONTRACEPTIVE
(YOGATANAKAR)
यिः खाादेदभयाररट्ररटा्लकं तथा
स जयेत सवधकु ष्ठापन ्ासादूर्ध्वं न संशयिः (ग.पन.2.36.87)
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69. कक्रभमरोगे
तनम्बििसमुद्िूिां रसां क्षौद्रयुिां विबेि् ।
धत्तूरििजां िावि कक्रभमनाशनमुत्तमम ् ।। (िा.प्र.चच.7.24)
In vitro ovicidal and larvicidal activity of Azadirachta indica
extracts on Haemonchus contortus
drrout.sibaprasad@gmail.com,24/06/2016
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71. mÉÑlÉlÉïuÉÉ
zÉÉåjÉÎblÉ(pÉÉ)
xɱÉåÌuÉzÉÉåÌwÉ(Måü);xÉkrÉÉå zÉÉåjÉ ÌuÉzÉÉåwÉrÉÌiÉ
xÉÉËUÍhÉ(xÉÉå)
ÌuÉwÉÎblÉ(UÉ):It is hepatoprotective and detoxifies the toxins
mÉÑlÉlÉïuÉÉ zÉÉMü-ÌuÉzÉåwÉÉiÉ zÉÉåTülÉÉzlÉ(xÉÑ.E.46/255)
िुननधवापन्बिटोलशुण्ठीपतक्ता्ृतादाव्यधभयाकषायिः
सवाधङगशोफोदरकासशूलश्वासापन्वतं िाण्डु गदं पन पन्त (वृ.्ा.38.3)
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72. Research
Ethanol extract of leaves at dose of 400mg/kgexhibited
maximum anti-inflammatory effect with30.4, 32.2, 33.9 and
32% with carrageenin,serotonin, histamine and dextran
induced rat pawedema models, respectively.Ethanol extract
of stembark also exhibited COX-1 and IC50value of
100ng/ml proving the drug use in thetreatment of
inflammatory condition. Antiinflammatoryactivity was
assessed using extract of latex of plant by using a carragenan
induced inflammatory model.47
Anti-inflammatory activity of Boerhaavia
diffusa.48 Bhalla, T.N., Gupta, M.B., Sheth, P.K., and Bhargava,
K.P., Antiinflammatory activity of Boerhaavia diffusa. Indian
Journal of Physiology and Pharmacology 1968; 12:37
drrout.sibaprasad@gmail.com,24/06/2016
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74. Mode of Action
The drug Bakuchi dilates the arterioles of the
subcapillary plexuses, so that the plasma is increased in
this area. The skin becomes red and the melanoblasts
(pigment-forming cells) are stimulated. In leukoderma,
melanoblasts do not function properly and their
stimulation by the drug leads them to form and exudate
pigments, which gradually diffuse into the white
leukodermic patches. Psoralen has been found to
intercalate into DNA, where they form mono- and di-
adducts in the presence of long wavelength UV light
and thus are used for the treatment of hypo-pigmented
lesions of the skin, such as leukoderma. [57]
Vaidya AD. Reverse Pharmacological correlates of Ayurvedic drug actions. Indian J
Pharmacol 2006;38:311-5
drrout.sibaprasad@gmail.com,24/06/2016
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76. Evaluation of anthelmintic activity of nuts of
Semecarpusanacardium
The anthelmintic activity of different extracts of nuts
of Semecarpus anacardium were evaluated separately on adult
Indian earthworm (Pheritima posthuma). It was found that
petroleum ether, chloroform extract of S. anacardium (PESA
and CESA, respectively) showed better anthelmintic activities
than ethanol (EESA) and aqueous (AESA) extract of it.
Antimicrobial activity of Semecarpus anacardium Linn.
nut extract
Alcoholic extract of dry nuts of S.anacardium showed dose
dependent antimicrobial activity in vitro against Aspergillus fumi
gatus andCandida albicans. At 400 mg/ml concentration, growth
of both the fungi was inhibited and considerable reduction in
size of cells and hyphae was observed.
Analgesic activity and acute toxicity study of Semecarpus
anacardium stem bark extracts using mice
Sharma, Kanika Shukla, Sunil DuttMehta, PoojaBhatnagar, Maheep
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