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Fissural cysts of oral origin
 Nasopalatine duct cyst
 Median palatal cyst
 Globulomaxillary cyst
 Median mandibular cyst
 Nasolabial cyst
 Palatal and alveolar cyst of new born (Epstein’s pearls and Bohn’s nodules)
 Thyroglossal cyst
 Epidermal inclusion cyst
 Dermoid cyst
 Heterotopic oral gastrointestinal cyst
Lymphoepithelial cyst
 Most common non odontogenic cyst
 Midline anterior maxilla
 Persistence of epithelial remnants
 Stimulus – trauma, infections
Clinical features
 Males, wide age range
 Small cyst- asymptomatic
 Large cyst- fluctuant swelling, discharge & pain
 Salty taste in mouth, devitalization of pulp
 Tooth displacement
 Extra bony cyst- soft tissue of incisive papilla- bluish colour dome shaped swelling
Treatment : enucleation
 Line of fusion of palatal processes of maxilla
 Mid line of hard palate between lateral palatal
processes
 Swelling – asymptomatic
 Radiographic- well circumscribed radiolucent area
bordered by sclerotic bone
 H/P- stratified squamous epithelium, dense fibrous
connective tissue, chronic inflammatory cell
infiltration.
 Pseudostratified ciliated columnar epithelium –
occasionally
 Treatment – surgical removal + curettage
 Between maxillary lateral incisor and canine
 Epithelial entrapment between medial nasal
process and maxillary process
 Bone suture between premaxilla and maxilla
 Often asymptomatic, pain – if infected
 Incidental finding in radiograph
 Inverted pear shape radiolucency between lateral
incisor and cuspid causing divergence of roots
Treatment
Surgical removal with
preservation of teeth
 Rare swelling in the mucolabial fold and in the floor of
the nose
 not visible on radiograph
 h/p – pseudostratified columnar epithelium, sometimes
with stratified squamous epithelium
 Treatment – careful surgical excision to prevent
perforation of the floor of the nose
 Extremely rare
 Midline of mandible
 Epithelial remnants entrapped in the median
mandibular fissure
 Asymptomatic expansion of cortical plates
 Incidental radiographic finding
 Unilocular / multilocular, well circumscribed
radiolucency
 h/p – thin, stratified squamous epithelium with many
folds
 Treatment – surgical excision with preservation of
teeth
Epstein’s pearls Bohn’s nodules
Entrapment of epithelial remnants From Palatal glandular structures
h/p – thin stratified squamous epithelium, connective tissue stroma,
Lumen- filled with keratin (onion rings)
Treatment – no treatment required
 Rare, benign, midline neck mass
 Dilation of a remnant at the site where the primitive thyroid
descended from its origin at the base of the tongue to the neck
 Palpable, asymptomatic, moves with swallowing
 h/p – stratified squamous epithelium, ciliated columnar
epithelium, connective tissue wall containing patches of
lymphoid tissue, thyroid tissue and mucous glands
 Treatment – antibiotics, if infected,
surgical excision of cyst, path’s tract and
branches
 Implantation of epidermal elements
 Source is often the infundibulum of hair follicle
 Asymptomatic, slow growth
 3rd to 4th decade of life
 Foul smelling , cheesy discharge
 Firm, round, mobile, subcutaneous nodules
 In oral location, it causes difficulty in feeding, swallowing
and phonation
 h/p – stratified squamous epithelium with glandular
differentiation, filled with keratin
Calcifications in connective tissue, malignant
transformation of epithelium is common
 Treatment – surgical removal
 Prognosis – malignant transformation: poor prognosis
 Hamartomatous tumor, multiple sebaceous
glands, skin adnexa (nails, dental, cartilage,
bone)
 Occurs on skin of face, neck, scalp
 Intra cranial, intra abdominal, ovary,
 3 sub classes : epidermoid cyst, dermoid
cyst & teratoid cyst
 h/p – lined by epidermis possessing
epidermal appendages, hair projecting in
lumen, sebaceous glands
 Treatment – surgical excision
 Esophagus, small intestine, thoracic cyst,
pancreas, gall bladder
 Oral cysts lined by gastric or intestinal
mucosa
 Tongue, floor of the mouth
 Any age, males
 Asymptomatic small nodule
 h/p – lined by stratified squamous epithelium as well
as gastric mucosa
 Treatment – surgical excision
 Benign lymphoid aggregate
 Cervical – branchial cleft cyst
 Entrapped duct epithelium in the lymph nodes
 Movable painless sub mucosal nodule, 0.6cm in
diameter
 Intra orally floor of the mouth, tongue, soft
palate, tonsils
 Ruptured to release foul tasting cheesy
keratinaceous material
 Clinically mimic dermoid or epidermoid cyst
 h/p – atrophic stratified squamous epithelium, no
rete ridges, minimal granular layer, goblet cells
 Treatment – surgical excision, no malignant
potential.
Non odontogenic cyst

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Non odontogenic cyst

  • 1.
  • 2.
  • 3. Fissural cysts of oral origin  Nasopalatine duct cyst  Median palatal cyst  Globulomaxillary cyst  Median mandibular cyst  Nasolabial cyst  Palatal and alveolar cyst of new born (Epstein’s pearls and Bohn’s nodules)  Thyroglossal cyst  Epidermal inclusion cyst  Dermoid cyst  Heterotopic oral gastrointestinal cyst Lymphoepithelial cyst
  • 4.  Most common non odontogenic cyst  Midline anterior maxilla  Persistence of epithelial remnants  Stimulus – trauma, infections Clinical features  Males, wide age range  Small cyst- asymptomatic  Large cyst- fluctuant swelling, discharge & pain  Salty taste in mouth, devitalization of pulp  Tooth displacement  Extra bony cyst- soft tissue of incisive papilla- bluish colour dome shaped swelling
  • 6.  Line of fusion of palatal processes of maxilla  Mid line of hard palate between lateral palatal processes  Swelling – asymptomatic  Radiographic- well circumscribed radiolucent area bordered by sclerotic bone  H/P- stratified squamous epithelium, dense fibrous connective tissue, chronic inflammatory cell infiltration.  Pseudostratified ciliated columnar epithelium – occasionally  Treatment – surgical removal + curettage
  • 7.  Between maxillary lateral incisor and canine  Epithelial entrapment between medial nasal process and maxillary process  Bone suture between premaxilla and maxilla  Often asymptomatic, pain – if infected  Incidental finding in radiograph  Inverted pear shape radiolucency between lateral incisor and cuspid causing divergence of roots
  • 9.  Rare swelling in the mucolabial fold and in the floor of the nose  not visible on radiograph  h/p – pseudostratified columnar epithelium, sometimes with stratified squamous epithelium  Treatment – careful surgical excision to prevent perforation of the floor of the nose
  • 10.  Extremely rare  Midline of mandible  Epithelial remnants entrapped in the median mandibular fissure  Asymptomatic expansion of cortical plates  Incidental radiographic finding  Unilocular / multilocular, well circumscribed radiolucency  h/p – thin, stratified squamous epithelium with many folds  Treatment – surgical excision with preservation of teeth
  • 11. Epstein’s pearls Bohn’s nodules Entrapment of epithelial remnants From Palatal glandular structures
  • 12. h/p – thin stratified squamous epithelium, connective tissue stroma, Lumen- filled with keratin (onion rings) Treatment – no treatment required
  • 13.  Rare, benign, midline neck mass  Dilation of a remnant at the site where the primitive thyroid descended from its origin at the base of the tongue to the neck  Palpable, asymptomatic, moves with swallowing  h/p – stratified squamous epithelium, ciliated columnar epithelium, connective tissue wall containing patches of lymphoid tissue, thyroid tissue and mucous glands  Treatment – antibiotics, if infected, surgical excision of cyst, path’s tract and branches
  • 14.  Implantation of epidermal elements  Source is often the infundibulum of hair follicle  Asymptomatic, slow growth  3rd to 4th decade of life  Foul smelling , cheesy discharge  Firm, round, mobile, subcutaneous nodules  In oral location, it causes difficulty in feeding, swallowing and phonation  h/p – stratified squamous epithelium with glandular differentiation, filled with keratin Calcifications in connective tissue, malignant transformation of epithelium is common  Treatment – surgical removal  Prognosis – malignant transformation: poor prognosis
  • 15.  Hamartomatous tumor, multiple sebaceous glands, skin adnexa (nails, dental, cartilage, bone)  Occurs on skin of face, neck, scalp  Intra cranial, intra abdominal, ovary,  3 sub classes : epidermoid cyst, dermoid cyst & teratoid cyst  h/p – lined by epidermis possessing epidermal appendages, hair projecting in lumen, sebaceous glands  Treatment – surgical excision
  • 16.  Esophagus, small intestine, thoracic cyst, pancreas, gall bladder  Oral cysts lined by gastric or intestinal mucosa  Tongue, floor of the mouth  Any age, males  Asymptomatic small nodule  h/p – lined by stratified squamous epithelium as well as gastric mucosa  Treatment – surgical excision
  • 17.  Benign lymphoid aggregate  Cervical – branchial cleft cyst  Entrapped duct epithelium in the lymph nodes  Movable painless sub mucosal nodule, 0.6cm in diameter  Intra orally floor of the mouth, tongue, soft palate, tonsils  Ruptured to release foul tasting cheesy keratinaceous material  Clinically mimic dermoid or epidermoid cyst  h/p – atrophic stratified squamous epithelium, no rete ridges, minimal granular layer, goblet cells  Treatment – surgical excision, no malignant potential.