Ten minute talk to the Staff Scientist and Staff Clinicians from NCI regarding bioinformatics resources.

1. Bioinformatics Resources An Incomplete List April 11, 2011, SS/SC Retreat Sean Davis, M.D., Ph.D. Genetics Branch, Center for Cancer Research National Cancer Institute National Institutes of Health

2. Normal Karyotype TumorKaryotype

3. The Central Dogma

4. Patient and Population Characteristics Gene Expression Gene Copy Number Transcriptional Regulation phenotype DNA Methylation Chromatin Structure and Function Sequence Variation

5. Overview Hardware Software Online databases Training and Education Getting Answers

6. Hardware Computers Current desktops quite capable High-performance resources Helix/Biowulf (CIT) Advanced Biomedical Computing Center (ABCC) Amazon EC2 Storage Local storage Helix/Biowulf NCI group drives

7. Software Commercial Open Source

8. Software

9. Software Bioconductor Bio-[Python, Java, Ruby, Perl] BRB ArrayTools GenePattern And the list goes on….

10. Software

11. Online Databases

12. Online Databases

13. Training and Education Google CIT/Helix training http://training.cit.nih.gov NIH Library http://nihlibrary.nih.gov/ResearchTools/Pages/Bioinformatics.aspx Cold Spring Harbor, AACR, OpenHelix, BioConductor, ….

14. Getting Answers Google http://seqanswers.com/ http://biostar.stackexchange.com/ http://bioinformatics.nci.nih.gov/ CCR Bioinformatics Core http://ccrifx.cancer.gov/

15. Contact and Acknowledgements