Trustworthiness of AI based predictions Aachen 2024
State-of-the-Art Overview of COPD and its Management
1. State-of-the-Art Overview of COPD and its Management David J Pierson MD Professor of Medicine University of Washington Seattle, WA, USA December, 2008
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5. Consensus Standards and Practice Guidelines for COPD Management GOLD : Respir Care . 2001 Aug;46(8):798-825; Updated Eur Respir J . 2003 Jul;22(1):1-2. www.goldcopd.com American Thoracic Society - European Thoracic Society : Eur Respir J . 2004 Jun;23(6):932-46. www.thoracic.org (Other national guidelines from Australia–New Zealand, Canada, Finland, France, Germany, India, Malaysia, South Africa, Switzerland, the UK, and others) Review and comparison of current guidelines: Pierson DJ, Respir Care 2006 (Mar);51(3):277-288.
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8. Change in Age-Adjusted US Death Rates, 1965-1998* *www.goldcopd.com Percentage of 1965 Rate 50 100 150 200 250 Coronary Heart Disease Stroke Other CVD All Other Causes COPD -59% -64% -35% +163% -7%
9. Deaths from COPD in the US *Mannino DM, Respir Care 2003;48(12):1185-91
21. Prognostic Value of Spirometry in COPD Survival among patients with COPD as a function of FEV 1 when first enrolled in cohort * = FEV 1 > 1.25 L = FEV 1 1.25-0.75 L = FEV 1 < 0.75 L (Correspond approximately to 2003 GOLD Stages II/III/IV) *Diener CF, Burrows B. Am Rev Respir Dis 1975;111:719-24
34. Effect of Long-Acting Beta 2 -Agonists on COPD Exacerbations* *Sin DD et al, JAMA 2003;290:2301-12 Meta-analysis of 9 clinical trials (4198 patients)
35. Effect of Tiotropium on COPD Exacerbations* *Sin DD et al, JAMA 2003;290:2301-12 Meta-analysis of 5 clinical trials (3574 patients)
36. Relationship Between FEV 1 and Effect of Inhaled Corticosteroids in Preventing COPD Exacerbations* Greater Effect in More Severely Obstructed Patients *Sin DD et al, JAMA 2003;290:2301-12
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44. Effect of Pulmonary Rehabilitation on Health-Related Quality of Life in COPD* *Sin DD et al, JAMA 2003;290:2301-12 Meta-analysis of 6 clinical trials (491 patients) SGRQ, St George’s Respiratory Questionnaire
45. Effects of Pulmonary Rehabilitation on Functional Exercise Capacity* *Lacasse Y et al, Cochrane Database Syst Rev 2006;Oct 18(4):CD007793
46. Effects of Pulmonary Rehabilitation on Dyspnea* *Lacasse Y et al, Cochrane Database Syst Rev 2006;Oct 18(4):CD007793
47. Effects of Pulmonary Rehabilitation on St Georges Respiratory Questionnaire (Total)* *Lacasse Y et al, Cochrane Database Syst Rev 2006;Oct 18(4):CD007793