2. INTRODUCTION
• Haemorrhagic disease of the newborn, also known
as vitamin K deficiency bleeding (VKDB), is
a coagulation disturbance in newborn infants due
to vitamin K deficiency.
• As a consequence of vitamin K deficiency there is an
impaired production of coagulation factors II, VII, IX,
X, protein C and protein S by the liver, resulting in
excessive bleeding (hemorrhage).
3. SIGNS&SYMPTOMS
• increased risk of bleeding.
• The most common sites of bleeding are
the umbilicus, mucous membranes gastrointestinal tract
circumcision and venopunctures.
4. CAUSES
• low vitamin K stores at birth
• vitamin K passes the placenta poorly
• levels of vitamin K in breast milk are low and the gut
flora has not yet been developed (vitamin K is normally
produced by intestinal bacteria).
5. CONGENITAL ANEMIA
• Congenital dyserythropoietic anemia (CDA) is an
inherited blood disorder that affects the development of
red blood cells.
• This disorder is one of many types of anemia, which is a
condition characterized by a shortage of red blood cells.
6. • This shortage prevents the blood from carrying an
adequate supply of oxygen to the body's tissues. The
resulting symptoms can include tiredness (fatigue),
weakness, pale skin, and other complications.
7. HEMOLYTIC ANEMIA
• Hemolysis is the premature destruction of erythrocytes. A
hemolytic anemia will develop if bone marrow activity
cannot compensate for the erythrocyte loss.
8. HYDROPS FETALIS
• Hydrops fetalis is a condition in the fetus characterized
by an accumulation of fluid, or edema, in at least
two fetal compartments. By comparison, hydrops
allantois or hydrops amnion is an accumulation of
excessive fluid in the allantoic or amniotic space,
respectively.
9. ICD-10-CM GUIDELINES
• Newborn affected by intrauterine (fetal) blood loss- P50
• Umbilical hemorrhage of newborn-P51
• Intracranial nontraumatic hemorrhage of newborn- P52
• Hemorrhagic disease of newborn- P53
• Other neonatal hemorrhages- P54
10. • Hemolytic disease of newborn- P55
• Hydrops fetalis due to hemolytic disease- P56
• Kernicterus-P57
• Neonatal jaundice due to other excessive hemolysis-
P58
• Neonatal jaundice from other and unspecified causes-
P59
11. • Disseminated intravascular coagulation of newborn- P60
• Other perinatal hematological disorders- P61
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