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Hacking My Gut
Microbiome
Richard Sprague
June 4, 2016
I’m not a doctor
• Disclaimer
• The following presentation and discussion is not intended to diagnose, treat, cure, or pre...
You
Weight
Human Non-Human
Cells
Human Non-Human
Genes
Human Non-Human
You
Weight
Human Non-Human
Cells
Human Non-Human
Genes
Human Non-Human
3 pounds
Find which microbes you have
{
"ubiome_bacteriacounts": [
{
"count": 611672,
"count_norm": 1008824,
"parent": 0,
"tax_rank": "root",
"tax_color": null,...
{
"ubiome_bacteriacounts": [
{
"count": 611672,
"count_norm": 1008824,
"parent": 0,
"tax_rank": "root",
"tax_color": null,...
Making science news personal
Bacteroides
Plebeius
Hacking my microbiome
0
10000
20000
30000
40000
50000
60000
70000
1 2 3 4 5
Count(normalized)
Sample
Bifidobacterium
Start Stop
Microbiome and sleep
Reseeding
Date Calories Carbs Fat Protein Cholesterol Sodium Sugars Fibre
15-Oct-15 2542 332 79 104 165 3339 53 48
17-Oct-...
My new friends
Abiotrophia Bacillus Catonella
Christensenella Parvimonas
What I Learned
• My gut microbiome recovers quickly
• Amounts and ratios change, but not the
organisms
• A few intriguing,...
Thank you!
• http://ubiome.com
@sprague
Biohackers Seattle June 2016 Microbiome Hacking
Biohackers Seattle June 2016 Microbiome Hacking
Biohackers Seattle June 2016 Microbiome Hacking
Biohackers Seattle June 2016 Microbiome Hacking
Biohackers Seattle June 2016 Microbiome Hacking
Biohackers Seattle June 2016 Microbiome Hacking
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Biohackers Seattle June 2016 Microbiome Hacking

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Details of my biohacking experiments with the microbiome.

Veröffentlicht in: Gesundheit & Medizin
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Biohackers Seattle June 2016 Microbiome Hacking

  1. 1. Hacking My Gut Microbiome Richard Sprague June 4, 2016
  2. 2. I’m not a doctor • Disclaimer • The following presentation and discussion is not intended to diagnose, treat, cure, or prevent any disease. • The material in my talk is provided for informational purposes only and is not medical advice. • Always consult your physician before beginning any diet or exercise program. • uBiome • uBiome sampling kits and data is designed to be a tool for personal research - not a diagnostic tool. uBiome cannot predict the implications of your results for your long-term health, nor will you be able to use your results to diagnose, treat, cure, or prevent any medical condition. • uBiome offers the opportunity to gain a better understanding of the human microbiome and see the bacteria in your own samples. • uBiome’s platform enables you to visualize your results, as they compare to other participant groups and your own samples over time.
  3. 3. You Weight Human Non-Human Cells Human Non-Human Genes Human Non-Human
  4. 4. You Weight Human Non-Human Cells Human Non-Human Genes Human Non-Human 3 pounds
  5. 5. Find which microbes you have
  6. 6. { "ubiome_bacteriacounts": [ { "count": 611672, "count_norm": 1008824, "parent": 0, "tax_rank": "root", "tax_color": null, "avg": null, "taxon": 1, "tax_name": "root" }, { "count": 606322, "count_norm": 1000000, "parent": 131567, "tax_rank": "superkingdom", "tax_color": null, "avg": null, "taxon": 2, "tax_name": "Bacteria“ },
  7. 7. { "ubiome_bacteriacounts": [ { "count": 611672, "count_norm": 1008824, "parent": 0, "tax_rank": "root", "tax_color": null, "avg": null, "taxon": 1, "tax_name": "root" }, tax_name tax_rank May-14 Jun-14 Oct-14 Jan-15 Feb-15 21-Apr 28-Apr Jun-15 Aug-15 Firmicutes phylum 62.288% 46.338% 58.450% 71.836% 67.930% 79.980% 68.885% 67.761% 63.708% Bacteroidetes phylum 25.573% 29.927% 27.485% 16.424% 14.900% 9.684% 13.602% 21.760% 18.289% Proteobacteria phylum 2.976% 15.625% 0.359% 0.982% 7.514% 1.584% 3.853% 2.111% 1.280% Actinobacteria phylum 1.097% 0.832% 6.562% 7.616% 0.771% 1.041% 0.382% 1.098% 0.967% Tenericutes phylum 0.636% 0.249% 0.043% 0.065% 0.071% 0.098% 0.647% 0.530% 0.003% Verrucomicrobia phylum 3.135% 1.965% 0.770% 0.664% 0.013% 1.155% 0.957% 0.236% 4.418% Euryarchaeota phylum 0.000% 0.000% 0.000% 0.000% 0.000% 2.425% 0.227% 0.225% 0.637% Lentisphaerae phylum 0.170% 0.000% 0.118% 0.017% 0.009% 0.018% 0.024% 0.107% 0.108% Cyanobacteria phylum 0.001% 0.000% 0.003% 0.005% 0.031% 0.005% 0.000% 0.096% 0.012% { "count": 606322, "count_norm": 1000000, "parent": 131567, "tax_rank": "superkingdom", "tax_color": null, "avg": null, "taxon": 2, "tax_name": "Bacteria“ }, 0% 20% 40% 60% 80% 100% May-14 Jun-14 Oct-14 Jan-15 Feb-15 21-Apr 28-Apr Jun-15 Aug-15 PhylumComposition Euryarchaeota Verrucomicrobia Tenericutes Actinobacteria Proteobacteria Bacteroidetes Firmicutes
  8. 8. Making science news personal
  9. 9. Bacteroides Plebeius
  10. 10. Hacking my microbiome
  11. 11. 0 10000 20000 30000 40000 50000 60000 70000 1 2 3 4 5 Count(normalized) Sample Bifidobacterium Start Stop
  12. 12. Microbiome and sleep
  13. 13. Reseeding Date Calories Carbs Fat Protein Cholesterol Sodium Sugars Fibre 15-Oct-15 2542 332 79 104 165 3339 53 48 17-Oct-15 1290 194 32 38 76 2907 58 19 18-Oct-15 0 0 0 0 0 0 0 0 19-Oct-15 0 0 0 0 0 0 0 0 20-Oct-15 2644 292 119 102 557 3266 61 41 21-Oct-15 2497 234 98 103 422 2593 89 44 22-Oct-15 2017 280 43 62 110 1577 58 29 23-Oct-15 2674 369 78 122 75 1305 49 36 24-Oct-15 2238 182 82 174 365 3123 62 30 25-Oct-15 1582 160 48 110 239 3084 38 19 26-Oct-15 1876 226 63 73 186 920 52 33 27-Oct-15 1771 173 62 97 767 1301 33 22 28-Oct-15 2190 291 88 100 252 1043 65 32 29-Oct-15 1768 161 88 90 267 1664 54 22 30-Oct-15 938 107 37 43 114 781 34 10 31-Oct-15 1637 251 42 94 223 4184 17 11 1-Nov-15 2133 198 69 100 380 1953 53 9 2-Nov-15 2142 269 76 60 306 2193 46 30 3-Nov-15 2019 300 97 70 255 2532 160 34 Cleans e
  14. 14. My new friends Abiotrophia Bacillus Catonella Christensenella Parvimonas
  15. 15. What I Learned • My gut microbiome recovers quickly • Amounts and ratios change, but not the organisms • A few intriguing, new organisms appeared. • It’s hard to significantly change your microbiome
  16. 16. Thank you! • http://ubiome.com @sprague

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