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AI Medical image Diagnostic Support Technology

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AI Medical image Diagnostic Support Technology

  1. 1. CEO Yuki Shimahara Ph.D. AI Medical Image Diagnostic Support Technology EIRL
  2. 2. 2 Company Name LPIXEL Inc. Foundation  March 4, 2014 Headquarters Tokyo, Japan Capital 2.07 Billion JPY (includes capital reserves) Investors CANON MEDICAL SYSTEMS CORPORATION, CYBERDYNE INC, FUJIFILM Corporation, JAFCO Co., Ltd., Mistletoe Inc., Olympus Corporation, SBI Investment, TECHMATRIX CORPORATION, TomyK, Toray Engineering Co., Ltd., Awards J-Startup, RED HERRING Global, SWITCH Employees 60 (pharmacists, and researchers) COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. Branch Office Boston, US
  3. 3. COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. 3 No.1
  4. 4. COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. 4 Workload of Radiologists 2008 2018 60 OVER% Serious shortage of doctors! Radiogram Interpretation An alternative solution to diagnosis is required MINISTRY OF HEALTH, LABOUR AND WELFARE DATA(2016)
  5. 5. 5COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. EIRL is the next medical image diagnostic support technology to catalyze the coming generation of medical diagnosis.
  6. 6. COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. 6 BRAIN SCREENING Aneurysm Stenosis Brain Measurements
  7. 7. 7COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. EIRL aneurysm • AI-assisted software for detecting brain aneurysms from brain MRA • Designed to reduce the number of overlooked lesions • Japan’s first deep learning-assisted SaMD to be approved by the PMDA
  8. 8. COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. 8 TECHNOLOGY This system is approved in accordance with the Act on Securing Quality, Efficacy and Safety of Products including Pharmaceuticals and Medical Devices (Pharmaceuticals and Medical Devices Law) in Japan. This system is not FDA cleared.
  9. 9. COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. 9 93 CAD Sensitivity “Deep learning for MR angiography: automated detection of cerebral aneurysms” Ueda D et al. Radiology 2018. 91% % 13 CAD Improved detection 4.8% % Sensitivity on 683 Aneurysms Presented at: The 77th Annual Meeting of the Japan Radiological Society Supported by: Osaka City University Graduate School of Medicine and Faculty of Medicine Department of Diagnostic and Interventional Radiology
  10. 10. 10COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. EIRL aneurysm: Radiologists’ Feedback It really helped when theAI identified lesions for the cases I was unsure of. “ “ It has an advantage in reducing the number of overlooked lesions that come from human error.“ “ I am satisfied with the analysis speed. “ “
  11. 11. 11COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. Colonoscopy • Together with the Jikei University School of Medicine, LPIXELis developing an 
 AI-assisted colonoscopy system that analyzes images in real-time for the 
 detection and differential diagnosis of colonic lesions
 • This national project is funded by the JapanAgency for Medical Research and 
 Development (AMED) 
 • TheAI is anticipated to lower the risk of colorectal cancer by reducing the 
 number of overlooked lesions and misdiagnosed cases
  12. 12. COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. 12 TECHNOLOGY This system is not FDA cleared.
  13. 13. COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. 13 98 91Detection Sensitivity % % Classification Sensitivity This system was able to detect 95 out of 102 lesions within 2 seconds of appearing in the colonoscopic image. Presented at: The 95th Congress of the Japan Gastroenterological Endoscopy Society, Digestive Disease Week Supported by: The Jikei University School of Medicine
  14. 14. 14COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. Future Vision
  15. 15. 15COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. Develop medical AI for other diseases Chest X-ray Mammography
  16. 16. 16COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. Cultivate a society where AI will become the norm • DevelopAI technologies and deliver them to the global market • CompileAI technologies from the world and bringing them medical institutions all across Japan through RAQA, sales and technical support
  17. 17. COPYRIGHT © LPIXEL INC. ALL RIGHTS RESERVED. Thank you for your kind attention

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