Dna Replication

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Jessica Leung Block D DNA Replication http://farm3.static.flickr.com/2272/2073342439_cfecc98a58.jpg

Nucleic Acids Storage, Transmission, and use genetic information Types: DNA and RNA Made of Nucleotides A pentose sugar, phosphate group, and a nitrogen-containing base Phosphodiester linkages http://upload.wikimedia.org/wikipedia/commons/2/2c/RNA_chemical_structure.GIF

DNA Structure: 4 Key Points Double stranded helix Right handed Anti-Parallel Outer edges of the nitrogenous bases are exposed in minor and major grooves http://upload.wikimedia.org/wikipedia/commons/9/9d/Water_drop_on_a_leaf.jpg http://farm4.static.flickr.com/3131/2849019437_d670cd8086.jpg http://farm4.static.flickr.com/3041/2735339035_62c0c6216d_o.jpg http://images.wellcome.ac.uk/indexplus/obf_images/6a/1b/dba050918296decdf63926d0b3af.jpg

Complementary Base PairingsMajor groove Minor groove 3’ 5’

Base Pairings DNA: Adenine, Cytosine, Guanine, Thymine RNA: Adenine, Cytosine, Guanine, Uracil

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Dna Replication

1. Jessica Leung Block D DNA Replication http://farm3.static.flickr.com/2272/2073342439_cfecc98a58.jpg

2. Basic Information About DNA

3. Nucleic Acids Storage, Transmission, and use genetic information Types: DNA and RNA Made of Nucleotides A pentose sugar, phosphate group, and a nitrogen-containing base Phosphodiester linkages http://upload.wikimedia.org/wikipedia/commons/2/2c/RNA_chemical_structure.GIF

4. DNA Structure: 4 Key Points Double stranded helix Right handed Anti-Parallel Outer edges of the nitrogenous bases are exposed in minor and major grooves http://upload.wikimedia.org/wikipedia/commons/9/9d/Water_drop_on_a_leaf.jpg http://farm4.static.flickr.com/3131/2849019437_d670cd8086.jpg http://farm4.static.flickr.com/3041/2735339035_62c0c6216d_o.jpg http://images.wellcome.ac.uk/indexplus/obf_images/6a/1b/dba050918296decdf63926d0b3af.jpg

6. Right handed

7. Anti-Parallel

8. Complementary Base PairingsMajor groove Minor groove 3’ 5’

9. Base Pairings DNA: Adenine, Cytosine, Guanine, Thymine RNA: Adenine, Cytosine, Guanine, Uracil

10. DNA REPLICATION!

11. DNA Replication in Two Steps (the Idea) Double Helix is unwound New Nucleotides are added http://images.wellcome.ac.uk/indexplus/obf_images/1f/db/51ca61b971d466050f9ed7d38edb.jpg http://upload.wikimedia.org/wikipedia/commons/7/78/DNA.three-models.1.jpg

12. The Big Idea Ligase Sliding DNA Clamp http://upload.wikimedia.org/wikipedia/commons/5/51/Leading_strand_replication.png http://www.multiplemomsrock.com/images/clamp.jpg http://www.tsl.state.tx.us/ld/projects/trc/2006/manual/illos/glue.jpg

13. Bibliography Sadava, David, H. Craig Heller, Gordon H. Orians, William K. Purves, and David M. Hillis. Life The Science of Biology. New York: W. H. Freeman, 2006. Print.