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Post R et al. Dietary Fiber for the
Treatment of Type 2 Diabetes Mellitus:
A Meta-Analysis
J Am Board Fam Med 2011; 25:16-23
http://twitter.com/pronutritionistPage 1
Page 2
Pronutritionist’s background
• High intake of fiber is linked to improved cardiovascular outcomes in
prospective cohort trials (Mente et al. 2009)
• Current dietary guidelines emphasize the role of dietary fiber in the
treatment of type diabetes (American diabetes association, 2008)
• Exact magnitude of the effect of increased fiber intake, in the context of
stable carbohydrate, fat and protein intake, is not known
http://twitter.com/pronutritionistPage 2 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
Methods (patients)
• A metal-analysis of controlled randomized trials
• Primary outcomes:
– Fasting glucose
– HbA1c
• Participants: Type 2 diabetics
• 15 trials included
• On average, observed difference in fiber intake was 18,3 grams/day
(40 grams per day)
• Follow up: 3-12 weeks
• Some trials used fiber supplements, some changed quality of bread or
cereals
• Both trials using soluble and in-soluble fiber were used
http://twitter.com/pronutritionistPage 3 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
Results
http://twitter.com/pronutritionistPage 4
0,85
mmol/l
0,26
%
Fasting blood glucose HbA1c
Effect of increased fiber intake (18,3 g/d) vs placebo in T2D
Post R et al. J Nutr. 2011 Dec;141(12):2180-5
Pronutritionist’s discussion
• This is the first meta-analysis to show the effect of increased fiber intake
in the control of type 2 diabetes in randomized setting
• The trials included were short. None of trials lasted more than 3 months.
More long term data is needed
• The meta-analysis supports the benefits of proposed high fiber intake in
the current diabetes guidelines
• If a diabetic patient is not able to increase use of vegetables, fruit and
whole grain, supplementation of fiber is justified according to this meta-
analysis
• It will be interesting to see if novel approaches to control blood glucose
will deliver similar effects, such as meal-time or bed-time vinegar intake
(Liatis et al. 2010)
http://twitter.com/pronutritionistPage 5 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
Please read the whole paper at
J Am Board Fam Med 2011;
25:16-23
http://twitter.com/pronutritionistPage 6
12/05/14
http://twitter.com/pronutritionist
http://www.facebook.com/pronutritionist
http://www.pronutritionist.net
Reijo Laatikainen, Authorized Nutritionist, MBA,
Dietitian
http://twitter.com/pronutritionistPage 7
Post R et al. J Nutr. 2011 Dec;141(12):2180-5

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Fiber and glycemia in type 2 diabetes

  • 1. Post R et al. Dietary Fiber for the Treatment of Type 2 Diabetes Mellitus: A Meta-Analysis J Am Board Fam Med 2011; 25:16-23 http://twitter.com/pronutritionistPage 1
  • 2. Page 2 Pronutritionist’s background • High intake of fiber is linked to improved cardiovascular outcomes in prospective cohort trials (Mente et al. 2009) • Current dietary guidelines emphasize the role of dietary fiber in the treatment of type diabetes (American diabetes association, 2008) • Exact magnitude of the effect of increased fiber intake, in the context of stable carbohydrate, fat and protein intake, is not known http://twitter.com/pronutritionistPage 2 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
  • 3. Methods (patients) • A metal-analysis of controlled randomized trials • Primary outcomes: – Fasting glucose – HbA1c • Participants: Type 2 diabetics • 15 trials included • On average, observed difference in fiber intake was 18,3 grams/day (40 grams per day) • Follow up: 3-12 weeks • Some trials used fiber supplements, some changed quality of bread or cereals • Both trials using soluble and in-soluble fiber were used http://twitter.com/pronutritionistPage 3 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
  • 4. Results http://twitter.com/pronutritionistPage 4 0,85 mmol/l 0,26 % Fasting blood glucose HbA1c Effect of increased fiber intake (18,3 g/d) vs placebo in T2D Post R et al. J Nutr. 2011 Dec;141(12):2180-5
  • 5. Pronutritionist’s discussion • This is the first meta-analysis to show the effect of increased fiber intake in the control of type 2 diabetes in randomized setting • The trials included were short. None of trials lasted more than 3 months. More long term data is needed • The meta-analysis supports the benefits of proposed high fiber intake in the current diabetes guidelines • If a diabetic patient is not able to increase use of vegetables, fruit and whole grain, supplementation of fiber is justified according to this meta- analysis • It will be interesting to see if novel approaches to control blood glucose will deliver similar effects, such as meal-time or bed-time vinegar intake (Liatis et al. 2010) http://twitter.com/pronutritionistPage 5 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
  • 6. Please read the whole paper at J Am Board Fam Med 2011; 25:16-23 http://twitter.com/pronutritionistPage 6
  • 7. 12/05/14 http://twitter.com/pronutritionist http://www.facebook.com/pronutritionist http://www.pronutritionist.net Reijo Laatikainen, Authorized Nutritionist, MBA, Dietitian http://twitter.com/pronutritionistPage 7 Post R et al. J Nutr. 2011 Dec;141(12):2180-5