SlideShare a Scribd company logo
1 of 36







Genetic material of living organisms is either
DNA or RNA.
DNA – Deoxyribonucleic acid
RNA – Ribonucleic acid
Genes are lengths of DNA that code for
particular proteins.

Monday, December 09,
2013

Pranabjyoti Das

1





Both DNA and RNA are polynucleotides.
They are made up of smaller molecules called
nucleotides.
DNA is made of two polynucleotide strands:

Nucleotide

Nucleotide

Nucleotide

Nucleotide

Nucleotide

Nucleotide

Nucleotide

Nucleotide

Nucleotide

Nucleotide



RNA is made of a single polynucleotide strand:

Nucleotide

Nucleotide

Monday, December 09,
2013

Nucleotide

Pranabjyoti Das

Nucleotide

Nucleotide

2
A nucleotide is made of 3
components:
 A Pentose sugar
 This is a 5 carbon
sugar
 The sugar in DNA is
deoxyribose.
 The sugar in RNA is
ribose.

Monday, December 09,
2013

Pranabjyoti Das

3



A Phosphate group
Phosphate groups are
important because
they link the sugar on
one nucleotide onto
the phosphate of the
next nucleotide to
make a
polynucleotide.

Monday, December 09,
2013

Pranabjyoti Das

4


A Nitogenous base



In DNA the four bases are:







Thymine
Adenine
Cytosine
Guanine

In RNA the four bases are:






Uracil
Adenine
Cytosine
Guanine

Monday, December 09,
2013

Pranabjyoti Das

5
Pyramidines

Purines

Thymine - T
Cytosine - C
Uracil - U

Adenine - A
Guanine - G

Monday, December 09,
2013

Pranabjyoti Das

6
Monday, December 09,
2013

Pranabjyoti Das

7
Monday, December 09,
2013

Pranabjyoti Das

8
Monday, December 09,
2013

Pranabjyoti Das

9




Nucleotides are
connected to each other
via the phosphate on
one nucleotide and the
sugar on the next
nucleotide
A Polynucleotide

Monday, December 09,
2013

Pranabjyoti Das

10
Monday, December 09,
2013

Pranabjyoti Das

11


The Nitrogenous
Bases pair up with
other bases. For
example the bases of
one strand of DNA
base pair with the
bases on the opposite
strand of the DNA.

Monday, December 09,
2013

Pranabjyoti Das

12
Monday, December 09,
2013

Pranabjyoti Das

13
Monday, December 09,
2013

Pranabjyoti Das

14
Monday, December 09,
2013

Pranabjyoti Das

15






Adenine always base pairs with Thymine (or
Uracil if RNA)
Cytosine always base pairs with Guanine.

This is beacuse there is exactly enough room
for one purine and one pyramide base between
the two polynucleotide strands of DNA.

Monday, December 09,
2013

Pranabjyoti Das

16
Purines

Pyramidines

Adenine
Adenine

Thymine
Uracil

Guanine

Cytosine

Monday, December 09,
2013

Pranabjyoti Das

17






Property 1 - it must contain, in a stable form,
information encoding the organism’s
structure, function, development and
reproduction
Property 2 - it must replicate accurately so
progeny cells have the same genetic makeup
Property 3 - it must be capable of some
variation (mutation) to permit evolution

Monday, December 09,
2013

Pranabjyoti Das

18




Speed of DNA replication:
3,000 nucleotides/min in human
30,000 nucleotides/min in E.coli
Accuracy of DNA replication:
Very precise (1 error/1,000,000,000 nt)

Monday, December 09,
2013

Pranabjyoti Das

19
Monday, December 09,
2013

Pranabjyoti Das

20
Monday, December 09,
2013

Pranabjyoti Das

21
Monday, December 09,
2013

Pranabjyoti Das

22
3H-labelled

after one further replication
Pranabjyoti Das
in unlabelled media 23

chromosomes

Monday, December 09,
2013
Monday, December 09,
2013

Pranabjyoti Das

24
Monday, December 09,
2013

Pranabjyoti Das

25
Monday, December 09,
2013

Pranabjyoti Das

26
Origins initiate
replication at
different
times.

Monday, December 09,
2013

Pranabjyoti Das

27
Monday, December 09,
2013

Pranabjyoti Das

28
Monday, December 09,
2013

Pranabjyoti Das

29
Monday, December 09,
2013

Pranabjyoti Das

30
Monday, December 09,
2013

Pranabjyoti Das

31
Monday, December 09,
2013

Pranabjyoti Das

32
Monday, December 09,
2013

Pranabjyoti Das

33
Monday, December 09,
2013

Pranabjyoti Das

34
Monday, December 09,
2013

Pranabjyoti Das

35
Monday, December 09,
2013

Pranabjyoti Das

36

More Related Content

What's hot

What's hot (20)

GENETIC CODE
GENETIC CODEGENETIC CODE
GENETIC CODE
 
Genetic codons
Genetic codonsGenetic codons
Genetic codons
 
Genetic code
Genetic codeGenetic code
Genetic code
 
Dna Basics
Dna BasicsDna Basics
Dna Basics
 
Prosyn1
Prosyn1Prosyn1
Prosyn1
 
Prosyn1
Prosyn1Prosyn1
Prosyn1
 
Genetic code
Genetic codeGenetic code
Genetic code
 
1. From Gene to Protein
1. From Gene to Protein1. From Gene to Protein
1. From Gene to Protein
 
Genetic code
Genetic codeGenetic code
Genetic code
 
Genetica molecular
Genetica molecularGenetica molecular
Genetica molecular
 
12.18.09 Theis Lab Group Presentation
12.18.09 Theis Lab Group Presentation12.18.09 Theis Lab Group Presentation
12.18.09 Theis Lab Group Presentation
 
12.3 dna, rna, and protein
12.3  dna, rna, and protein12.3  dna, rna, and protein
12.3 dna, rna, and protein
 
Suguna
SugunaSuguna
Suguna
 
Dna history
Dna historyDna history
Dna history
 
Genetic code
Genetic codeGenetic code
Genetic code
 
Autobiography of frederick sanger double nobel prize winner
Autobiography of frederick sanger   double nobel prize winnerAutobiography of frederick sanger   double nobel prize winner
Autobiography of frederick sanger double nobel prize winner
 
Synthesis of gene
Synthesis of geneSynthesis of gene
Synthesis of gene
 
RNA structure
RNA structureRNA structure
RNA structure
 
Dna polymerase
Dna polymeraseDna polymerase
Dna polymerase
 
genetic code
genetic codegenetic code
genetic code
 

Viewers also liked (7)

About The Gene Therapy
About The Gene TherapyAbout The Gene Therapy
About The Gene Therapy
 
Gene therapy
Gene therapyGene therapy
Gene therapy
 
si-RNA delivery
si-RNA deliverysi-RNA delivery
si-RNA delivery
 
Genetic screening & gene therapy
Genetic screening & gene therapyGenetic screening & gene therapy
Genetic screening & gene therapy
 
Gene therapy
Gene therapyGene therapy
Gene therapy
 
Gene therapy
Gene therapy Gene therapy
Gene therapy
 
Gene therapy
Gene therapyGene therapy
Gene therapy
 

Similar to Structure of DNA

Nucletides and Nucleic acids.ppt
Nucletides and Nucleic acids.pptNucletides and Nucleic acids.ppt
Nucletides and Nucleic acids.ppt
Perfect40
 

Similar to Structure of DNA (20)

Nucleic Acids (DNA & RNA)
Nucleic Acids (DNA & RNA)Nucleic Acids (DNA & RNA)
Nucleic Acids (DNA & RNA)
 
Nucleic acid
Nucleic acidNucleic acid
Nucleic acid
 
Structure of dna and replication2009
Structure of dna and replication2009Structure of dna and replication2009
Structure of dna and replication2009
 
Nucleic Acid
Nucleic AcidNucleic Acid
Nucleic Acid
 
DNA Grade 12
DNA Grade 12DNA Grade 12
DNA Grade 12
 
Molecular basis of life: Structures and function of DNA and RNA
Molecular basis of life: Structures and function of DNA and RNAMolecular basis of life: Structures and function of DNA and RNA
Molecular basis of life: Structures and function of DNA and RNA
 
The Structure Of A Double Helix
The Structure Of A Double HelixThe Structure Of A Double Helix
The Structure Of A Double Helix
 
DNA vs RNA Top 8 Common Differences!.pdf
DNA vs RNA  Top 8 Common Differences!.pdfDNA vs RNA  Top 8 Common Differences!.pdf
DNA vs RNA Top 8 Common Differences!.pdf
 
200L MBBS, NUCLEOSIDES ETC-1.pptx
200L MBBS, NUCLEOSIDES ETC-1.pptx200L MBBS, NUCLEOSIDES ETC-1.pptx
200L MBBS, NUCLEOSIDES ETC-1.pptx
 
Nucleic acids
Nucleic acids Nucleic acids
Nucleic acids
 
nucleic acids chap.5 biochemistry.pdf
nucleic acids chap.5 biochemistry.pdfnucleic acids chap.5 biochemistry.pdf
nucleic acids chap.5 biochemistry.pdf
 
Dna and rna
Dna and rnaDna and rna
Dna and rna
 
Chapter 6 biology 20 12-15
Chapter 6 biology 20 12-15Chapter 6 biology 20 12-15
Chapter 6 biology 20 12-15
 
Nucletides and Nucleic acids.ppt
Nucletides and Nucleic acids.pptNucletides and Nucleic acids.ppt
Nucletides and Nucleic acids.ppt
 
Genetics lec
Genetics lecGenetics lec
Genetics lec
 
RNA PRESENTATION.pptx
RNA PRESENTATION.pptxRNA PRESENTATION.pptx
RNA PRESENTATION.pptx
 
DNA structure and replication molecular biology
DNA structure and replication molecular biologyDNA structure and replication molecular biology
DNA structure and replication molecular biology
 
Nucleic acid
Nucleic acidNucleic acid
Nucleic acid
 
physiology...protein
physiology...proteinphysiology...protein
physiology...protein
 
Dna Cloning
Dna CloningDna Cloning
Dna Cloning
 

More from Dr. Pranabjyoti Das

More from Dr. Pranabjyoti Das (20)

Arunodoi Jr College, Tangla at a glance.
Arunodoi Jr College, Tangla at a glance.Arunodoi Jr College, Tangla at a glance.
Arunodoi Jr College, Tangla at a glance.
 
CAREER POINT
CAREER POINTCAREER POINT
CAREER POINT
 
Surface Tension for Beginners
Surface Tension for BeginnersSurface Tension for Beginners
Surface Tension for Beginners
 
DEGRADATION OF THE RIVERINE ECOSYSTEM OF NAIKA RIVER
DEGRADATION OF THE RIVERINE ECOSYSTEM OF NAIKA RIVERDEGRADATION OF THE RIVERINE ECOSYSTEM OF NAIKA RIVER
DEGRADATION OF THE RIVERINE ECOSYSTEM OF NAIKA RIVER
 
Municipal Dumping Site and Its Health Hazards to the proximate communities at...
Municipal Dumping Site and Its Health Hazards to the proximate communities at...Municipal Dumping Site and Its Health Hazards to the proximate communities at...
Municipal Dumping Site and Its Health Hazards to the proximate communities at...
 
Science is Awesome
Science  is  AwesomeScience  is  Awesome
Science is Awesome
 
Excretory system in Human (Class 10)
Excretory system in Human (Class 10)Excretory system in Human (Class 10)
Excretory system in Human (Class 10)
 
Acids, Bases and Salts
Acids, Bases and SaltsAcids, Bases and Salts
Acids, Bases and Salts
 
Aspects of Solar Geyser in saving Energy & Nature
Aspects of Solar Geyser in  saving Energy & NatureAspects of Solar Geyser in  saving Energy & Nature
Aspects of Solar Geyser in saving Energy & Nature
 
Evolution of Heart
Evolution of HeartEvolution of Heart
Evolution of Heart
 
Carbon and Its Compound
Carbon and Its CompoundCarbon and Its Compound
Carbon and Its Compound
 
Photosynthesis
Photosynthesis Photosynthesis
Photosynthesis
 
Cell Division
Cell DivisionCell Division
Cell Division
 
Occurance of Metals
Occurance of MetalsOccurance of Metals
Occurance of Metals
 
Chemical Properties of Metals (Class 10)
Chemical Properties of Metals (Class 10)Chemical Properties of Metals (Class 10)
Chemical Properties of Metals (Class 10)
 
Metal and Nonmetal (Class 10)
Metal and Nonmetal (Class 10)Metal and Nonmetal (Class 10)
Metal and Nonmetal (Class 10)
 
Cell Signaling
Cell SignalingCell Signaling
Cell Signaling
 
Flight Mechanism in Birds
Flight Mechanism in BirdsFlight Mechanism in Birds
Flight Mechanism in Birds
 
Flight Muscles of Birds
Flight Muscles of BirdsFlight Muscles of Birds
Flight Muscles of Birds
 
Science is awesome
Science  is  awesomeScience  is  awesome
Science is awesome
 

Recently uploaded

The basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptxThe basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptx
heathfieldcps1
 
Salient Features of India constitution especially power and functions
Salient Features of India constitution especially power and functionsSalient Features of India constitution especially power and functions
Salient Features of India constitution especially power and functions
KarakKing
 

Recently uploaded (20)

The basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptxThe basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptx
 
Towards a code of practice for AI in AT.pptx
Towards a code of practice for AI in AT.pptxTowards a code of practice for AI in AT.pptx
Towards a code of practice for AI in AT.pptx
 
Application orientated numerical on hev.ppt
Application orientated numerical on hev.pptApplication orientated numerical on hev.ppt
Application orientated numerical on hev.ppt
 
NO1 Top Black Magic Specialist In Lahore Black magic In Pakistan Kala Ilam Ex...
NO1 Top Black Magic Specialist In Lahore Black magic In Pakistan Kala Ilam Ex...NO1 Top Black Magic Specialist In Lahore Black magic In Pakistan Kala Ilam Ex...
NO1 Top Black Magic Specialist In Lahore Black magic In Pakistan Kala Ilam Ex...
 
Sensory_Experience_and_Emotional_Resonance_in_Gabriel_Okaras_The_Piano_and_Th...
Sensory_Experience_and_Emotional_Resonance_in_Gabriel_Okaras_The_Piano_and_Th...Sensory_Experience_and_Emotional_Resonance_in_Gabriel_Okaras_The_Piano_and_Th...
Sensory_Experience_and_Emotional_Resonance_in_Gabriel_Okaras_The_Piano_and_Th...
 
Food safety_Challenges food safety laboratories_.pdf
Food safety_Challenges food safety laboratories_.pdfFood safety_Challenges food safety laboratories_.pdf
Food safety_Challenges food safety laboratories_.pdf
 
Fostering Friendships - Enhancing Social Bonds in the Classroom
Fostering Friendships - Enhancing Social Bonds  in the ClassroomFostering Friendships - Enhancing Social Bonds  in the Classroom
Fostering Friendships - Enhancing Social Bonds in the Classroom
 
Graduate Outcomes Presentation Slides - English
Graduate Outcomes Presentation Slides - EnglishGraduate Outcomes Presentation Slides - English
Graduate Outcomes Presentation Slides - English
 
Mehran University Newsletter Vol-X, Issue-I, 2024
Mehran University Newsletter Vol-X, Issue-I, 2024Mehran University Newsletter Vol-X, Issue-I, 2024
Mehran University Newsletter Vol-X, Issue-I, 2024
 
ICT Role in 21st Century Education & its Challenges.pptx
ICT Role in 21st Century Education & its Challenges.pptxICT Role in 21st Century Education & its Challenges.pptx
ICT Role in 21st Century Education & its Challenges.pptx
 
Micro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdfMicro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdf
 
Wellbeing inclusion and digital dystopias.pptx
Wellbeing inclusion and digital dystopias.pptxWellbeing inclusion and digital dystopias.pptx
Wellbeing inclusion and digital dystopias.pptx
 
Google Gemini An AI Revolution in Education.pptx
Google Gemini An AI Revolution in Education.pptxGoogle Gemini An AI Revolution in Education.pptx
Google Gemini An AI Revolution in Education.pptx
 
Basic Civil Engineering first year Notes- Chapter 4 Building.pptx
Basic Civil Engineering first year Notes- Chapter 4 Building.pptxBasic Civil Engineering first year Notes- Chapter 4 Building.pptx
Basic Civil Engineering first year Notes- Chapter 4 Building.pptx
 
Sociology 101 Demonstration of Learning Exhibit
Sociology 101 Demonstration of Learning ExhibitSociology 101 Demonstration of Learning Exhibit
Sociology 101 Demonstration of Learning Exhibit
 
Accessible Digital Futures project (20/03/2024)
Accessible Digital Futures project (20/03/2024)Accessible Digital Futures project (20/03/2024)
Accessible Digital Futures project (20/03/2024)
 
Salient Features of India constitution especially power and functions
Salient Features of India constitution especially power and functionsSalient Features of India constitution especially power and functions
Salient Features of India constitution especially power and functions
 
HMCS Max Bernays Pre-Deployment Brief (May 2024).pptx
HMCS Max Bernays Pre-Deployment Brief (May 2024).pptxHMCS Max Bernays Pre-Deployment Brief (May 2024).pptx
HMCS Max Bernays Pre-Deployment Brief (May 2024).pptx
 
SOC 101 Demonstration of Learning Presentation
SOC 101 Demonstration of Learning PresentationSOC 101 Demonstration of Learning Presentation
SOC 101 Demonstration of Learning Presentation
 
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
 

Structure of DNA