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EASTBIO, Dundee, Scotland, 2019-06-13
Early Career Researchers and Open Bioscience*
Peter Murray-Rust1,2
[1]University of Cambridge[2]TheContentMine [peter@contentmine.org]
Start Early, Be Open, Be Brave
20-30 ECRs I have had the privilege of knowing and the stories of some.
*flavours: synthetic biology, informatics, plants
Themes for ECRs / Synbio
• ECR journeys
• Advocacy
• Community
• Infrastructure
• Tools
– Knowledge
– Materials
– Hardware
1 2
A
C
I
K
M
H
(ContentMine) software can do a simple triage in a few minutes
Ellie: “there were 10,000 abstracts and due
to time pressures, we split this between 6
researchers. It took about 2-3 days of work
(working only on this) to get through
~1,600 papers each. So, at a minimum this
equates to 12 days of full-time work (and
would normally be done over several weeks
under normal time pressures).”
The Knowledge Problem…you can’t read this
Systematic Literature ReviewsK
(2x digital music industry!)
ContentMine is an OpenLocked Non-Profit company
Millions of Open facts
The Right to Read is the Right to Mine
ContentMine automates knowledge extraction
K
Synthetic Biology, Cambridge
Jim Haseloff, Jenny Molloy Google search
K M H
1
Panton Authors and Fellows
Jenny
Molloy
(undergrad)
Panton Arms
Pub Cambridge
2009 Panton Principles
For Open Science Data
Ross Mounce
Sophie Kay-Kershaw
Sam Smith
Open publishing
Peter Kraker
Open Knowledge
Maps
Panton Fellowship program
1
32
K
Oxford 2013
Berlin 2014
Delhi 2014
ContentMine-ing
Community
Gita Yadav
4
15 years
later
Jenny
goes to
India
Why Open?
• Better Science (in every aspect)
• Quicker
• Flexible
• Inclusive
• Preservable
• Principled
• Open comes from the heart
• ACT: Advocacy , Community, Tools
A C
Community
PMR’s Shuttleworth Flash Grantees
• Erin McKiernan (Open Access)
• Daniel Mietchen (Wikimedian)
• Joe McArthur (Right to Research, SPARC)
• Chris Hartgerink (Text mining)
• Pinkie Chan* (Fighting land grabs in Cambodia w OpenData)
• Heather Piwowar (Impact Story, Unpaywall)
• Sophie Kay-Kershaw (OSTI, reproducibility)
• Corina Logan (Bullied into Bad Science)
• Jon Tennant (Open Science MOOC)
• Lorraine Chuen (Opencon)
Alongside formal study / research
A
K
A
A
I
I
A
I
A
Unpaywall
Jason
Priem
Heather
Piwowar
https://unpaywall.org/products/extension
A gamechanger. Professionally run and hopefully reaching the stage where
publishers can’t afford NOT to be in unpaywall.
Expect more APIs and discovery over the next year.
I
Daniel Mietchen, Wikimedia
https://en.wikipedia.org/wiki/Wikipedia:Wikipedia_Signpost/2011-07-25/Wikimedian_in_Residence_interview
https://en.wikipedia.org/wiki/User:Daniel_Mietchen
https://commons.wikipedia.org/wiki/User:Daniel_Mietchen
Thesupermat - Own work Intervention de Daniel Mietchen aux Rencontres Wikimedia France. CC BY-SA 3.0
File:Rencontres Wikimedia France - Intervention de Daniel Mietchen.JPG Created: 4 December 2010
K
#DontLeaveItToGoogle
Peter Kraker An Open Infrastructure is essential
Or…
...Mendeley
…WebOfScience
…Scopus
… Elsevier
…Springer-Nature
https://elephantinthelab.org/google-and-research-data/
Repositories: BASE , EuropePMC
Free articles: Unpaywall
Preprints: arXiv, bioRxiv, medRxiv
Indexing: Crossref
Scraping: getpapers, quickscrape
Text analysis: OpenKnowledgeMaps, ami
2
I
getpapers
Rik Smith-Unna
To install the software see http://github.com/petermr/tigr2ess
I
Julia Reda, Pirate MEP, running ContentMine
software to liberate science 2016-04-16A
5-year fight for liberating EU copyright
WE HAVE FAILED!
#article11 #article13/17
Hyperlinks Upload filters
6 ContentMine Fellows for 6 months in 2016
Alexandra Bannach-Brown
 Edinburgh, Neuroscience
 Problem: huge body of works in animal studies about depressions. systematic review is the main
approach for getting insight.
 Wants: identify papers in systematic review of depressive behaviour in animals. What
drugs, what methods, what outcomes and signs/phenotypes. Use outcomes for document
clustering.
 and expedite scientific advances."
 Corpus: 70.000 Papers
K
Lars Willighagen
 15 years old (NL)
 Wants: data about conifers and phytochemicals
 Outcome: database with webpage containing conifer properties
 Table Facts Visualiser DEMO
 Card DEMO
 Word Cloud
 „ I applied to this fellowship to learn new things and combine the ContentMine with two previous
projects I never got to finish, and I got really excited by the idea and the ContentMine at large.“
3
I
Giulia Arsuffi (Cambridge)
3-month DTP/PIPS intern
with ContentMine
Marchantia, a model organism for plant synthetic biology
Automatically extracting Marchantia
knowledge from hundreds of Open articles
K
Poster at OpenPlant 2018
4
1-day ContentMine workshop developed by ECRs in Delhi
Extracting knowledge for crops (wheat, rice millets)
K I
4
Ambarish has to lookup thousands
of species and chemicals.
PMR tweets “help!
2 Ross Mounce replies in <10 minutes.
K
Makespace -> Biomakespace
Jenny Molloy: Practical affordable synthetic biology for all
A
M H
Open Bioeconomy, Jenny Molloy 1
M
Challenges artificial scarcity (patents, supplier monopolies)
H
Maker technology (3-D printing, laser cutting, Raspberry PI…)
@Senficon (Julia Reda) :Text & Data mining in times of
#copyright maximalism:
"Elsevier stopped me doing my research"
http://onsnetwork.org/chartgerink/2015/11/16/elsevi
er-stopped-me-doing-my-research/ … #opencon #TDM
Elsevier stopped me doing my research
Chris Hartgerink
ECRs often feel pressured into taking actions
against our ethics to pursue an academic career
(e.g., publishing in particular journals)
ECRs: Sign the petition to help us change academic culture
Non-ECRs: Join the supporters by valuing open practices, especially
when making decisions about hiring, promotion, and grants
Leading individuals and institutions
in adopting open practices to
improve research rigor
We won’t be…
Corina Logan & Laurent
Gatto
BIBS Leading Team: Dr. Laurent Gatto, Dr. Ross Mounce, Dr. Stephen Eglen, Dr. Adrian
Currie, Dr. Lauren Maggio
www.BulliedIntoBadScience.org | Twitter: #BulliedIntoBadScience
ContentMine.org
Systematic review technology
Open Thoughts for ECRs
An Open presence:
Blog, reviews, software, data resources, advocacy, activism.
Think globally. Redalyc (Latam), africarxiv, GOSH
Collaborate.
Work with/in industry
Write code or collect Open data
Create Makespaces
Go to Open Science meetings, hacks
Imagine futures.
Have fun
Other options than becoming an academic?
Believe in yourself!
Resources :
http://sparcopen.org is good starting place. Also the ECRs mentioned are
very approachable.
ContentMine.org
• Systematic reviews
• Extracting data from diagrams
• Internships
• Training
• Collaborative proposals
END
I am a statistician interested in detecting potentially problematic research such as data fabrication,
which results in unreliable findings and can harm policy-making, confound funding decisions, and
hampers research progress.
To this end, I am content mining results reported in the psychology literature. Content mining the
literature is a valuable avenue of investigating research questions with innovative methods. For
example, our research group has written an automated program to mine research papers for errors in
the reported results and found that 1/8 papers (of 30,000) contains at least one result that could
directly influence the substantive conclusion [1].
In new research, I am trying to extract test results, figures, tables, and other information reported in
papers throughout the majority of the psychology literature. As such, I need the research papers
published in psychology that I can mine for these data. To this end, I started ‘bulk’ downloading research
papers from, for instance, Sciencedirect. I was doing this for scholarly purposes and took into account
potential server load by limiting the amount of papers I downloaded per minute to 9. I had no intention
to redistribute the downloaded materials, had legal access to them because my university pays a
subscription, and I only wanted to extract facts from these papers.
Full disclosure, I downloaded approximately 30GB of data from Sciencedirect in approximately 10 days.
This boils down to a server load of 0.0021GB/[min], 0.125GB/h, 3GB/day.
Approximately two weeks after I started downloading psychology research papers, Elsevier notified my
university that this was a violation of the access contract, that this could be considered stealing of
content, and that they wanted it to stop. My librarian explicitly instructed me to stop downloading
(which I did immediately), otherwise Elsevier would cut all access to Sciencedirect for my university.
I am now not able to mine a substantial part of the literature, and because of this Elsevier is directly
hampering me in my research.
[1] Nuijten, M. B., Hartgerink, C. H. J., van Assen, M. A. L. M., Epskamp, S., & Wicherts, J. M. (2015). The
prevalence of statistical reporting errors in psychology (1985–2013). Behavior Research Methods, 1–22.
doi: 10.3758/s13428-015-0664-2
Chris Hartgerink’s blog post
Opening Knowledge overcomes
injustice
• Open comes from the heart.
• Closed Access Means People Die.
• Megacorporations are pwning the knowledge
infrastructure/
• The Right to Read is the Right to Mine
• Young people change the world. Give them
the chance.
• ACT: Advocacy , Community, Tools
Ross Mounce
Bioscientist and palaeontologist
Tireless champion of Open and gadfly of
publishers.
When still a grad student he championed “The
Right to Mine” in The European Commission,
defeating the publishers’ “Licences for Europe”
Early Career Reseachers in Science. Start Early, Be Open , Be Brave
Early Career Reseachers in Science. Start Early, Be Open , Be Brave
Early Career Reseachers in Science. Start Early, Be Open , Be Brave
Early Career Reseachers in Science. Start Early, Be Open , Be Brave
Early Career Reseachers in Science. Start Early, Be Open , Be Brave

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Early Career Reseachers in Science. Start Early, Be Open , Be Brave

  • 1. EASTBIO, Dundee, Scotland, 2019-06-13 Early Career Researchers and Open Bioscience* Peter Murray-Rust1,2 [1]University of Cambridge[2]TheContentMine [peter@contentmine.org] Start Early, Be Open, Be Brave 20-30 ECRs I have had the privilege of knowing and the stories of some. *flavours: synthetic biology, informatics, plants
  • 2. Themes for ECRs / Synbio • ECR journeys • Advocacy • Community • Infrastructure • Tools – Knowledge – Materials – Hardware 1 2 A C I K M H
  • 3. (ContentMine) software can do a simple triage in a few minutes Ellie: “there were 10,000 abstracts and due to time pressures, we split this between 6 researchers. It took about 2-3 days of work (working only on this) to get through ~1,600 papers each. So, at a minimum this equates to 12 days of full-time work (and would normally be done over several weeks under normal time pressures).” The Knowledge Problem…you can’t read this Systematic Literature ReviewsK
  • 4. (2x digital music industry!) ContentMine is an OpenLocked Non-Profit company Millions of Open facts The Right to Read is the Right to Mine ContentMine automates knowledge extraction K
  • 5. Synthetic Biology, Cambridge Jim Haseloff, Jenny Molloy Google search K M H 1
  • 6. Panton Authors and Fellows Jenny Molloy (undergrad) Panton Arms Pub Cambridge 2009 Panton Principles For Open Science Data Ross Mounce Sophie Kay-Kershaw Sam Smith Open publishing Peter Kraker Open Knowledge Maps Panton Fellowship program 1 32 K
  • 7. Oxford 2013 Berlin 2014 Delhi 2014 ContentMine-ing Community Gita Yadav 4 15 years later Jenny goes to India
  • 8. Why Open? • Better Science (in every aspect) • Quicker • Flexible • Inclusive • Preservable • Principled • Open comes from the heart • ACT: Advocacy , Community, Tools A C
  • 10. PMR’s Shuttleworth Flash Grantees • Erin McKiernan (Open Access) • Daniel Mietchen (Wikimedian) • Joe McArthur (Right to Research, SPARC) • Chris Hartgerink (Text mining) • Pinkie Chan* (Fighting land grabs in Cambodia w OpenData) • Heather Piwowar (Impact Story, Unpaywall) • Sophie Kay-Kershaw (OSTI, reproducibility) • Corina Logan (Bullied into Bad Science) • Jon Tennant (Open Science MOOC) • Lorraine Chuen (Opencon) Alongside formal study / research A K A A I I A I A
  • 11. Unpaywall Jason Priem Heather Piwowar https://unpaywall.org/products/extension A gamechanger. Professionally run and hopefully reaching the stage where publishers can’t afford NOT to be in unpaywall. Expect more APIs and discovery over the next year. I
  • 12. Daniel Mietchen, Wikimedia https://en.wikipedia.org/wiki/Wikipedia:Wikipedia_Signpost/2011-07-25/Wikimedian_in_Residence_interview https://en.wikipedia.org/wiki/User:Daniel_Mietchen https://commons.wikipedia.org/wiki/User:Daniel_Mietchen Thesupermat - Own work Intervention de Daniel Mietchen aux Rencontres Wikimedia France. CC BY-SA 3.0 File:Rencontres Wikimedia France - Intervention de Daniel Mietchen.JPG Created: 4 December 2010 K
  • 13. #DontLeaveItToGoogle Peter Kraker An Open Infrastructure is essential Or… ...Mendeley …WebOfScience …Scopus … Elsevier …Springer-Nature https://elephantinthelab.org/google-and-research-data/ Repositories: BASE , EuropePMC Free articles: Unpaywall Preprints: arXiv, bioRxiv, medRxiv Indexing: Crossref Scraping: getpapers, quickscrape Text analysis: OpenKnowledgeMaps, ami 2 I
  • 14. getpapers Rik Smith-Unna To install the software see http://github.com/petermr/tigr2ess I
  • 15. Julia Reda, Pirate MEP, running ContentMine software to liberate science 2016-04-16A 5-year fight for liberating EU copyright WE HAVE FAILED! #article11 #article13/17 Hyperlinks Upload filters
  • 16. 6 ContentMine Fellows for 6 months in 2016
  • 17. Alexandra Bannach-Brown  Edinburgh, Neuroscience  Problem: huge body of works in animal studies about depressions. systematic review is the main approach for getting insight.  Wants: identify papers in systematic review of depressive behaviour in animals. What drugs, what methods, what outcomes and signs/phenotypes. Use outcomes for document clustering.  and expedite scientific advances."  Corpus: 70.000 Papers K
  • 18. Lars Willighagen  15 years old (NL)  Wants: data about conifers and phytochemicals  Outcome: database with webpage containing conifer properties  Table Facts Visualiser DEMO  Card DEMO  Word Cloud  „ I applied to this fellowship to learn new things and combine the ContentMine with two previous projects I never got to finish, and I got really excited by the idea and the ContentMine at large.“ 3 I
  • 19. Giulia Arsuffi (Cambridge) 3-month DTP/PIPS intern with ContentMine Marchantia, a model organism for plant synthetic biology Automatically extracting Marchantia knowledge from hundreds of Open articles K Poster at OpenPlant 2018
  • 20. 4 1-day ContentMine workshop developed by ECRs in Delhi Extracting knowledge for crops (wheat, rice millets) K I
  • 21. 4 Ambarish has to lookup thousands of species and chemicals. PMR tweets “help! 2 Ross Mounce replies in <10 minutes. K
  • 22. Makespace -> Biomakespace Jenny Molloy: Practical affordable synthetic biology for all A M H
  • 23. Open Bioeconomy, Jenny Molloy 1 M Challenges artificial scarcity (patents, supplier monopolies)
  • 24. H Maker technology (3-D printing, laser cutting, Raspberry PI…)
  • 25. @Senficon (Julia Reda) :Text & Data mining in times of #copyright maximalism: "Elsevier stopped me doing my research" http://onsnetwork.org/chartgerink/2015/11/16/elsevi er-stopped-me-doing-my-research/ … #opencon #TDM Elsevier stopped me doing my research Chris Hartgerink
  • 26. ECRs often feel pressured into taking actions against our ethics to pursue an academic career (e.g., publishing in particular journals) ECRs: Sign the petition to help us change academic culture Non-ECRs: Join the supporters by valuing open practices, especially when making decisions about hiring, promotion, and grants Leading individuals and institutions in adopting open practices to improve research rigor We won’t be… Corina Logan & Laurent Gatto BIBS Leading Team: Dr. Laurent Gatto, Dr. Ross Mounce, Dr. Stephen Eglen, Dr. Adrian Currie, Dr. Lauren Maggio www.BulliedIntoBadScience.org | Twitter: #BulliedIntoBadScience
  • 28. Open Thoughts for ECRs An Open presence: Blog, reviews, software, data resources, advocacy, activism. Think globally. Redalyc (Latam), africarxiv, GOSH Collaborate. Work with/in industry Write code or collect Open data Create Makespaces Go to Open Science meetings, hacks Imagine futures. Have fun Other options than becoming an academic? Believe in yourself! Resources : http://sparcopen.org is good starting place. Also the ECRs mentioned are very approachable.
  • 29. ContentMine.org • Systematic reviews • Extracting data from diagrams • Internships • Training • Collaborative proposals
  • 30. END
  • 31.
  • 32. I am a statistician interested in detecting potentially problematic research such as data fabrication, which results in unreliable findings and can harm policy-making, confound funding decisions, and hampers research progress. To this end, I am content mining results reported in the psychology literature. Content mining the literature is a valuable avenue of investigating research questions with innovative methods. For example, our research group has written an automated program to mine research papers for errors in the reported results and found that 1/8 papers (of 30,000) contains at least one result that could directly influence the substantive conclusion [1]. In new research, I am trying to extract test results, figures, tables, and other information reported in papers throughout the majority of the psychology literature. As such, I need the research papers published in psychology that I can mine for these data. To this end, I started ‘bulk’ downloading research papers from, for instance, Sciencedirect. I was doing this for scholarly purposes and took into account potential server load by limiting the amount of papers I downloaded per minute to 9. I had no intention to redistribute the downloaded materials, had legal access to them because my university pays a subscription, and I only wanted to extract facts from these papers. Full disclosure, I downloaded approximately 30GB of data from Sciencedirect in approximately 10 days. This boils down to a server load of 0.0021GB/[min], 0.125GB/h, 3GB/day. Approximately two weeks after I started downloading psychology research papers, Elsevier notified my university that this was a violation of the access contract, that this could be considered stealing of content, and that they wanted it to stop. My librarian explicitly instructed me to stop downloading (which I did immediately), otherwise Elsevier would cut all access to Sciencedirect for my university. I am now not able to mine a substantial part of the literature, and because of this Elsevier is directly hampering me in my research. [1] Nuijten, M. B., Hartgerink, C. H. J., van Assen, M. A. L. M., Epskamp, S., & Wicherts, J. M. (2015). The prevalence of statistical reporting errors in psychology (1985–2013). Behavior Research Methods, 1–22. doi: 10.3758/s13428-015-0664-2 Chris Hartgerink’s blog post
  • 33. Opening Knowledge overcomes injustice • Open comes from the heart. • Closed Access Means People Die. • Megacorporations are pwning the knowledge infrastructure/ • The Right to Read is the Right to Mine • Young people change the world. Give them the chance. • ACT: Advocacy , Community, Tools
  • 34. Ross Mounce Bioscientist and palaeontologist Tireless champion of Open and gadfly of publishers. When still a grad student he championed “The Right to Mine” in The European Commission, defeating the publishers’ “Licences for Europe”